ライフサイエンスコーパス: AAA protein

1 associated with diverse cellular activities (AAA proteins).

2 of evolutionary change that characterize the AAA proteins.

3 exameric ring organisation characteristic of AAA proteins.

4 tide-related allosteric signals in a class-1 AAA+ protein.

5 ns, aligns with a key catalytic Arg found in AAA+ proteins.

6 insights into the mechanisms of MgsA family AAA+ proteins.

7 stinguishes it from other clamp loader clade AAA+ proteins.

8 ary dystonia, is called the torsin family of AAA+ proteins.

9 (54) activators as pre-sensor 1 beta-hairpin AAA+ proteins.

10 reviously found only in distinct families of AAA+ proteins.

11 ilarity with the large and diverse family of AAA+ proteins.

12 e to identify similar residue pairs in other AAA(+) proteins.

13 orII helix in PspF, which may apply to other AAA(+) proteins.

14 vation in the origin of those events amongst AAA(+) proteins.

15 similar to adaptor-binding domains of other AAA(+) proteins.

16 Rubisco activase is an AAA(+) protein, a superfamily with members that use a "S

17 hown that the modular domain architecture of AAA proteins allows for precise control of cellular acti

18 dentification of an evolutionarily conserved AAA+ protein, ANCCA/pro2000, endowed with a bromodomain

19 multiple cell types appear to utilize torsin AAA+ proteins and differential expression of torsinB may

20 The common oligomeric structures of AAA+ proteins and the creation of the active site for AT

21 ing and helical lid domains (conserved among AAA+ proteins) and a tetramerization domain.

22 Torsins are developmentally essential AAA+ proteins, and mutation of human torsinA causes the

23 The AAA proteins are characterized by the presence of a 230

24 spindle formation, but functions for the SF7 AAA proteins are largely unknown.

25 AAA proteins are molecular chaperones that facilitate a

26 AAA proteins are oligomeric and often have multiple ATPa

27 AAA(+) proteins are ubiquitous mechanochemical ATPases t

28 r II helix that has been implicated in other AAA+ proteins as sensing changes in the nucleotide durin

29 Mutations in the AAA+ protein (ATPase associated with a variety of cellul

30 The AAA proteins (ATPases Associated with a variety of cellu

31 that bears similarity to the FtsH family of AAA proteins (ATPases associated with diverse cellular a

32 They belong to the family of AAA+ proteins (ATPases associated with various cellular

33 hI and BchD subunits belong to the family of AAA+ proteins (ATPases associated with various cellular

34 AAA+ proteins (ATPases associated with various cellular

35 ymes as members of the clamp loader clade of AAA+ proteins, but structural information defining the f

36 of particular interest for understanding how AAA+ proteins carry out multiple ATP driven functions.

37 VAT), the archaeal homolog of the ubiquitous AAA+ protein Cdc48/p97, functions in concert with the 20

38 o this event, two of the three subunits, the AAA(+) proteins ChlI and ChlD, form a ChlID-MgATP comple

39 ication factor C (RFC) is a heteropentameric AAA+ protein clamp loader of the proliferating cell nucl

40 l partially explained by the presence of the AAA(+) protein ComGA, which is also required for the bin

41 The AAA+ protein disaggregase Hsp104 can sever the amyloid f

42 ome formation and identified novel mammalian AAA+ protein disaggregases RuvbL1 and RuvbL2.

43 ot have a C-terminal helical domain as other AAA proteins do.

44 associated with various cellular activities (AAA) proteins, especially in the mononucleotide binding

45 These activators belong to the large AAA protein family and the majority of them consist of a

46 t AMP-AlF(x) is a powerful new tool to study AAA(+) protein family members and, more generally, Walke

47 transcription activators that belong to the AAA(+) protein family.

48 e ATPase associated with diverse activities (AAA) protein family and is involved in mitochondrial mor

49 associated with diverse cellular activities (AAA) protein family, and contains a microtubule interact

50 r the C terminus of torsinA, a member of the AAA+ protein family (ATPases associated with a variety o

51 r binding proteins (bEBP) are members of the AAA+ protein family and have a highly conserved 'DE' Wal

52 ic peptidase B homolog ClpB, a member of the AAA+ protein family.

53 associated with various cellular activities (AAA+) protein family, are required to remodel the transc

54 classifying this gene as a new member of the AAA-protein family (ATPase associated with diverse activ

55 ontrast, Methanosarcina mazei contains seven AAA proteins, five of which, both PAN proteins, two out

56 Many other AAA proteins form ring-shaped hexamers and contain pore

57 Fidgetin is the first mutant AAA protein found in a mammalian developmental mutant, t

58 is a dynamic ring translocase and hexameric AAA+ protein found in yeast, which couples ATP hydrolysi

59 Hsp104, a conserved hexameric AAA+ protein from yeast, solubilizes disordered aggregat

60 The homologous hexameric AAA(+) proteins, Hsp104 from yeast and ClpB from bacteri

61 NSF and p97 are related AAA proteins implicated in membrane trafficking and orga

62 a new member of the cdc48p/VCP subfamily of AAA proteins in Drosophila.

63 p97(E578Q)) to compare the function of these AAA proteins in the secretory pathway of mammalian cells

64 mutation (WB(EQ)) that typically stabilizes AAA+ proteins in a substrate-bound state causes torsinA

65 dimer adopts a novel oligomeric assembly for AAA+ proteins in which the arginine finger, crucial for

66 to the establishment of different functional AAA proteins, including proteasomal regulatory, NSF/Sec,

67 Several AAA+ proteins, including ClpB/Hsp104, possess a pair of

68 A feature common to AAA+ proteins is the formation of oligomeric rings that

69 greatest similarity to the VCP subfamily of AAA proteins, is widely expressed, and encodes a nuclear

70 tumor antigen (LTag) of simian virus 40, an AAA(+) protein, is a hexameric helicase essential for vi

71 TorsinA is an AAA(+) protein located predominantly in the lumen of the

72 TorsinA is an AAA+ protein located predominantly in the lumen of the e

73 g/remodeling by this conserved and essential AAA+ protein machine and their adaption and possible bio

74 nce when considering how activities of other AAA(+) proteins might be controlled.

75 n motor domain is constructed from a ring of AAA protein modules, with the C-terminal module position

76 ease is allosterically activated by HslU, an AAA protein of the Clp/Hsp100 family consisting of three

77 Human AAA(+) protein p97 consists of an N-domain and two tande

78 For one type of member AAA(+) protein (phage shock protein F, PspF), we identif

79 AAA+ proteins play crucial roles in diverse biological p

80 c AAA ATPase p97 is perhaps the best studied AAA protein, playing an essential role in various import

81 dent interactions and consideration of other AAA+ proteins provide insight into activator mechanochem

82 ssociated with assorted cellular activities (AAA+) proteins, raising the possibility that expression

83 Here, we investigated the mechanism of the AAA+ protein Rubisco activase (Rca) in metabolic repair

84 AAA proteins share a conserved active site for ATP hydro

85 Precedence to other AAA(+) proteins suggests that Mcm ATPase active sites ar

86 p60 katanin, an AAA protein that severs and depolymerizes microtubules,

87 TIP48 and TIP49 are two related AAA(+) proteins that are essential for the formation of

88 trates a reverse-chaperoning activity for an AAA+ protein that can act as a template for the assembly

89 Regulatory ATPase variant A (RavA) is a MoxR AAA+ protein that functions together with a partner prot

90 similarity of Aquifex aeolicus DnaA to other AAA+ proteins that are oligomeric, it was proposed that

91 tivators of the bacterial sigma(54)-RNAP are AAA+ proteins that couple ATP hydrolysis to restructure

92 A subgroup of the AAA+ proteins that reside in the endoplasmic reticulum a

93 taining Domain (CAD) proteins (also known as AAA proteins) that are involved in a wide variety of cel

94 TorsinA is an "AAA" protein thought to reside in the endoplasmic reticu

95 hydrolysis of ATP is universally required by AAA+ proteins to underpin their mechano-chemical work.

96 By contrast to other AAA+ proteins, torsin proteins contain two conserved cys

97 A glutamic acid deletion (DeltaE) in the AAA+ protein torsinA causes DYT1 dystonia.

98 03)) in the carboxyl-terminal portion of the AAA+ protein, torsinA.

99 rally applicable to the examination of other AAA+ protein translocases involved in a variety of impor

100 associated with various cellular activities (AAA) protein Vps4.

101 4 is a member of the CDC48p/VCP subfamily of AAA proteins which are involved in homotypic fusion of t

102 two related and highly conserved eukaryotic AAA(+) proteins with an essential biological function an