ライフサイエンスコーパス: ABH1

1 anisms contribute to ABA hypersensitivity of abh1.

2 tive nuclear mRNA cap-binding protein mutant abh1.

3 ring although it is a weaker suppressor than abh1.

4 vity in double mutants of sad2-1 and sad1 or abh1-7, a newly isolated allele of ABH1 also in the RD29

5 nit of the nuclear mRNA cap-binding protein, ABH1 (ABA hypersensitive1).

6 Three human homologs, ABH1, ABH2 and ABH3, have been identified, and two of th

7 bh1 and WT, which together with results from abh1/abi1-1 double-mutant analyses suggest that abh1 sho

8 d sad1 or abh1-7, a newly isolated allele of ABH1 also in the RD29A:LUC background, suggested that SA

9 Here, we show that the dimeric ABH1 and AtCBP20 subunits are ubiquitously expressed.

10 omplex genetic interactions, suggesting that ABH1 and ERA1 do not modulate the same negative regulato

11 the model that the mRNA-processing proteins ABH1 and SAD1 function as negative regulators in guard c

12 he soa1 phenotype is dominant in relation to abh1 and segregates as a single locus.

13 showed similar primary humidity responses in abh1 and WT, which together with results from abh1/abi1-

14 ing, revealed a possible link between CBP80 (ABH1) and ABI4 presented here.

15 Whole-plant growth phenotypes of abh1 are described and properties of ABH1 in guard cells

16 oles of SAD2 in relation to that of SAD1 and ABH1 are discussed.

17 By using abh1 as an enhancer of mRNA metabolism events, we identi

18 in order to decipher the interaction between ABH1 (CBP80) and other components of ABA signaling.

19 ABH1 (CBP80) encodes a large subunit of CBC (CAP BINDING

20 We find that ABH1/CBP80 is necessary to obtain proper mature miRNA le

21 s of XRN4/EIN5, a 5'-3' exoribonuclease, and ABH1/CBP80, a subunit of the mRNA cap binding complex, r

22 Stomatal apertures were smaller in abh1 compared with wild type (WT) when plants were grown

23 However, ABH1 did not show any repair activity.

24 ABH1 encodes the Arabidopsis homolog of a nuclear mRNA c

25 ABH1 encodes the large subunit of a dimeric Arabidopsis

26 Together, abh1 enhances steps in the RNA metabolism that allowed u

27 ABH1 failed to cross-link to the probes tested.

28 lines expressing a green fluorescent protein-ABH1 fusion protein demonstrate that ABH1 mainly localiz

29 potassium channel currents were decreased in abh1 guard cells compared with WT.

30 ypersensitive cytosolic calcium increases in abh1 guard cells demonstrate amplification of early ABA

31 The mutant named soa1 (suppressor of abh1 hypersensitivity to ABA 1) displayed an ABA-insensi

32 2CA cDNA fusion in abh1 partially suppresses abh1 hypersensitivity, and the data further suggest that

33 ypes of abh1 are described and properties of ABH1 in guard cells are further analyzed.

34 n unexpected role of the cap-binding protein ABH1 in miRNA biogenesis.

35 ere revealed by an early flowering mutation, abh1, in an Arabidopsis nuclear mRNA cap-binding protein

36 show here that down-regulation of AtPP2CA in abh1 is not due to impaired RNA splicing of AtPP2CA pre-

37 The serrated leaf morphology of abh1 is similar to the serrate (se) mutant and, like abh

38 The abh1 lesion affects several developmental processes, per

39 Complemented abh1 lines expressing a green fluorescent protein-ABH1 f

40 protein-ABH1 fusion protein demonstrate that ABH1 mainly localizes in guard cell nuclei.

41 ty of FRI to increase FLC mRNA levels in the abh1 mutant background.

42 subunit of CBC (CAP BINDING COMPLEX) and the abh1 mutant is drought-tolerant and hypersensitive to AB

43 r, expression of a 35SAtPP2CA cDNA fusion in abh1 partially suppresses abh1 hypersensitivity, and the

44 Consistent with these results, abh1 plants show ABA-hypersensitive stomatal closing and

45 Thus, ABH1 represents a modulator of ABA signaling proposed to

46 similar to the serrate (se) mutant and, like abh1, se is also a suppressor of FRI-mediated late flowe

47 only a few transcripts are down-regulated in abh1, several of which are implicated in ABA signaling.

48 In each case, abh1 showed altered patterns in RNA metabolism in these

49 hypersensitive signaling mutants, era1-2 and abh1, showed complex genetic interactions, suggesting th

50 1/abi1-1 double-mutant analyses suggest that abh1 shows enhanced sensitivity to endogenous ABA.

51 lated a recessive ABA hypersensitive mutant, abh1, that shows hormone specificity to ABA.

52 Unlike se, in abh1 the rate of leaf production and the number of juven

53 date, nine human AlkB homologues are known: ABH1 to ABH8 and the obesity-related FTO.

54 The suppressor mutants of abh1 were generated after chemical mutagenesis.

55 ntly characterized a new Arabidopsis mutant, abh1, which shows ABA-hypersensitive regulation of seed