ライフサイエンスコーパス: AFP

1 AFP also inhibited transcription of the miR-29a/b-1 locu

2 AFP confirms the performance evidenced in other studies,

3 AFP level was evaluated against patient characteristics,

4 AFP responders at 1 mo had better overall survival than

5 AFP surveillance indicators were assessed at the nationa

6 AFP surveillance quality in children aged <15 years impr

7 AFP was incubated in Ab1-coated wells; unbound AFP was t

8 AFPs have gained a large interest for their use in antif

9 nt (P < 0.001); KPS improvement (P < 0.001); AFP improvement (P < 0.001)] and reduction of therapeuti

10 onders, at 8.5 mo versus 4.8 mo (P = 0.018); AFP responders at 3 mo had overall survival of 13.3 mo,

11 ents with cirrhosis, results from at least 1 AFP test, and 6 months of follow-up.

12 R >/= 5 (P < 0.0001, hazard ratio, HR: 6.2), AFP > 200 (P < 0.0001, HR: 3.8), and Size >3 cm (P < 0.0

13 ies, Gunma, Japan) and AFP (IMMULITE(R) 2000 AFP, Siemens Healthcare Diagnostics, Tarrytown, New York

14 During 2010-2012, AFP cases were reported from all provinces but not every

15 could be expanded to the TTV (</=115 cm(3) )/AFP (</=400 ng/mL) criteria in centers with at least 8-m

16 tis C virus-related cirrhosis in whom 35,494 AFP tests were performed, and 987 patients developed HCC

17 idation cohort (AUROC: urinary panel = 0.72; AFP = 0.58).

18 t (Maximum Mid-Expiratory Flow, MMEF25-75%), AFP and CEA for never smokers, light and never smokers w

19 Of 40 926 AFP cases reported in LAC from 1992-2011, we identified

20 s were isolated from stool specimens of 9263 AFP cases and 1059 contacts, respectively.

21 tion of age, tumor site, and stage in > 94%, AFP in 12%, and YST in 27% of the replications.

22 limited value In diagnosing nvHCC, Having a AFP value over 400 ng/ml was associated with aggressive

23 Absolute AFP values did not correlate with SUV parameters (P = 0.

24 eptides, the assay can quantify low abundant AFP expression (0.5 ng) with good correlation with conve

25 break immune tolerance and potently activate AFP-specific CD8 T cells, generating effective antitumor

26 Although AFP surveillance met national performance standards, wid

27 We constructed an AFP-based algorithm that included these factors to ident

28 n in the TCLT and in a model derived from an AFP-negative relapsing HB.

29 ater than 18 months (HR, 1.6; P = 0.043) and AFP greater than 400 at HCC diagnosis (HR, 3.0; P < 0.00

30 methylation profiling reveals that AFP+ and AFP- HCC tumors have distinct global DNA methylation pat

31 ain the autonomous regulation of albumin and AFP genes in the liver after birth.

32 d interaction terms between AFP and ALT, and AFP and platelets), best discriminated between patients

33 ch as family history of lung cancer, CEA and AFP for light smokers, and lung function test (Maximum M

34 tion of two major cancer biomarkers (CEA and AFP) in different approaches.

35 Both DCP and AFP were tested using enzyme immunoassay methods.

36 EXT III, PRETEXT IV, metastatic disease, and AFP concentration of 100 ng/mL or lower at diagnosis.

37 ples were tested for both GPC3 by ELISA, and AFP by immunometric assay.

38 gy differs considerably between AFP+ HCC and AFP- HCC; AFP is a functional antagonist of miR-29, whic

39 criteria, macroscopic vascular invasion, and AFP score>2 were independent predictors of recurrence, w

40 o-Biological Laboratories, Gunma, Japan) and AFP (IMMULITE(R) 2000 AFP, Siemens Healthcare Diagnostic

41 logen (Vio) electrochemical redox marker and AFP monoclonal antibody (mAb) on the surface of Au-PAMAM

42 Comparing the two groups, AUC for OPN and AFP were 0.51 (95 % CI: 0.39-0.63) and 0.79 (95 % CI: 0.

43 by baseline liver function, tumor size, and AFP level.

44 r staging, CPS, ECOG performance status, and AFP.

45 rence in tumor stage between ultrasound- and AFP-detected tumors (P = 0.53).

46 Such a combination of trehalose and AFPs also provides a novel approach for cold protection

47 The capture anti-AFP (Ab1) was coated onto polystyrene well plates and bo

48 ts were used to label one member of the anti-AFP pair (Ab2) via amine-amine coupling using glutaralde

49 VAPP was defined as any AFP case with residual paralysis 60 days following onset

50 Polio cases were defined as AFP cases with stool specimens positive for WPV.

51 e 5 cm or smaller, solitary lesion, baseline AFP level lower than 100 ng/dL, and Eastern Cooperative

52 ed fish AFGPs (AFGP8, AFGP1-5), and a beetle AFP (DAFP1) with increasing antifreeze activity as poten

53 s also a feature of the similar-sized beetle AFP that is a beta-helix with seven 12-residue coils and

54 The midge and beetle AFPs are not homologous and their ice-binding sites are

55 Tumor biology differs considerably between AFP+ HCC and AFP- HCC; AFP is a functional antagonist of

56 we examine the molecular recognition between AFP and trehalose crystal interfaces using molecular dyn

57 e of AFP test (and interaction terms between AFP and ALT, and AFP and platelets), best discriminated

58 43.8% were detected by ultrasound, 31.2% by AFP, and 25.0% by both surveillance tests.

59 Stratifying patients by AFP status in addition to radiological criteria may impr

60 enografts showed expression of beta-catenin, AFP, and Glypican-3 (GPC3).

61 In contrast, AFP showed significant differences among different group

62 to further improve accuracy of conventional AFP-L3 tests.

63 al analysis was performed using a decreasing AFP of at least 20% as a standard of reference for thera

64 rived normal AFP (nAFP) or HCC tumor-derived AFP (tAFP), and DC phenotype and function were assessed.

65 ricated immunosensor could accurately detect AFP concentration in human serum samples demonstrated by

66 found that the proposed method could detect AFP antigen at a wide linear range (0.001-45 ng mL(-1))

67 ed device was successfully applied to detect AFP in human serum.

68 e predictive accuracy increased at different AFP cutoffs compared with AFP alone.

69 ut nonmetastatic, HCC and initially elevated AFP, possibly enabling early therapy monitoring independ

70 measured in expression of PAPPA, FLT1, ENG, AFP, PGF, and LGALS14, but not LGALS13 or the lineage ma

71 et that is classified by an extreme EpCAM(+) AFP(+) gene expression signature and associated with poo

72 serve as a key molecular target for EpCAM(+) AFP(+) HCC subtype.

73 coprotein specifically activated in EpCAM(+) AFP(+) HCC.

74 erum 25OH-vitamin D, serum alfa-fetoprotein (AFP)) were performed on a cohort of 200 Egyptian CHC pat

75 rs, and 8 years or older; alpha fetoprotein (AFP) concentration of 100 ng/mL or lower and 101-1000 ng

76 er of 3 to 5 cm and serum alpha fetoprotein (AFP) greater than 100 ng/mL at transplant yielded a 50%

77 rveillance ultrasound and alpha fetoprotein (AFP) tests have minimal direct harm, downstream harms fr

78 antigen (CEA), bilirubin, alpha fetoprotein (AFP), and c-reactive protein (CRP) were identified and i

79 Elevated alpha-fetoprotein (AFP) >/= 10,000 ng/mL was associated with worse outcome,

80 ents with a high level of alpha-fetoprotein (AFP) (>100 ng/dL) was conducted.

81 serum tumor markers were alpha-fetoprotein (AFP) 2.0 ng/mL, human chorionic gonadotropin (hCG) 151,1

82 sed two model biomarkers [alpha-fetoprotein (AFP) and cancer antigen 125 (CA125)] to demonstrate the

83 Serum levels of alpha-fetoprotein (AFP) are influenced not only by the presence of hepatoce

84 ree patients had elevated alpha-fetoprotein (AFP) at diagnosis.

85 REAT), which incorporates alpha-fetoprotein (AFP) at liver transplantation (LT), microvascular invasi

86 ted self/tumor antigen of alpha-fetoprotein (AFP) could be engineered to create an effective vaccine

87 ymphocyte ratio (NLR) and alpha-fetoprotein (AFP) have been associated with recurrence risk.

88 ild-Pugh score (CPS), and alpha-fetoprotein (AFP) in predicting individual survival.

89 nsitive and specific than Alpha-fetoprotein (AFP) in the diagnosis of HCC among the White population.

90 Alpha-fetoprotein (AFP) is a biomarker for hepatocellular carcinoma (HCC).

91 Serum alpha-fetoprotein (AFP) is a biomarker for hepatocellular carcinomas (HCCs)

92 alpha-fetoprotein (AFP) is an oncofetal Ag that is highly expressed in abno

93 the sensitivity of serum alpha-fetoprotein (AFP) is too low for this purpose.

94 atients (542 men), median alpha-fetoprotein (AFP) level at the time of LT was 8.3 ng/mL; 9.4% had mic

95 em, tumor size, and serum alpha-fetoprotein (AFP) level were investigated using Cox proportional haza

96 stases and a rising serum alpha-fetoprotein (AFP) level.

97 Alpha-fetoprotein (AFP) represents a classical model system to study develo

98 developed to detect human alpha-fetoprotein (AFP) using carbon dots (C-Dots).

99 under optimal conditions, alpha-fetoprotein (AFP) was detected at a limit of detection of 1ngmL(-1) a

100 Levels of human alpha-fetoprotein (AFP) were monitored in the serum of animals.

101 rface antigen (HBsAg) and alpha-fetoprotein (AFP) with the lowest concentration of naked-eye detectio

102 As demonstrated on alpha-fetoprotein (AFP), a serum biomarker for hepatocellular carcinoma (HC

103 ciated gene expression of alpha-fetoprotein (AFP), Albumin (Alb), Glucose-6-phosphatase (G6Pc), SRY (

104 al advantages compared to alpha-fetoprotein (AFP), but its role in the context of alcoholic cirrhosis

105 oembryonic antigen (CEA), alpha-fetoprotein (AFP), cancer antigen 125 (CA125), and carbohydrate antig

106 tides spanning the entire alpha-fetoprotein (AFP), glypican-3 (GPC-3), melanoma-associated gene-A1 (M

107 onal serum marker for HB, alpha-fetoprotein (AFP), has its limitations.

108 with elevated circulating alpha-fetoprotein (AFP), low rate of necrosis/fibrosis after treatment, and

109 Serum alpha-fetoprotein (AFP), normally highly expressed in the liver only during

110 was associated with serum alpha-fetoprotein (AFP), tumor-node-metastasis (TNM) stage, and lymph node

111 or trace level sensing of alpha-fetoprotein (AFP), which is a well know cancer biomarker.

112 umour burden score (TBS), alpha-fetoprotein (AFP), year of transplantation, underlying cause of cirrh

113 tion of cancer biomarker, alpha-fetoprotein (AFP).

114 lume (TTV; </=115 cm(3) )/alpha-fetoprotein (AFP; </=400 ng/mL) score.

115 as patients with negative alpha-fetoprotein (AFP; n = 1), resulting in 24 patients and 57 scans that

116 internal clathrate water network of the fish AFP Maxi, which extends to the protein's outer surface,

117 ZBTB20 was dispensable for AFP silencing in other tissues outside liver.

118 cluded in the immunosensor modification (for AFP: 1st and 3rd approaches: 1.36fg/ml in comparison wit

119 immunosensor exhibited high specificity for AFP detection, extremely short incubation time (5 min),

120 n efficient alternative detection system for AFP measurement with detection limit 0.5ngmL(-1) and con

121 we report a previously unidentified role for AFPs in effectively inhibiting trehalose precipitation i

122 This newly uncovered role for AFPs may help explain the long-speculated role of AFPs i

123 tober accounting for 79.3% of isolation from AFP cases with known month of specimen collection.

124 expression of AFP, or conditioned media from AFP+ cells, inhibits miR-29a expression and induces DNMT

125 the spruce budworm Choristoneura fumiferana AFP, including stereo-specific binding and consequential

126 Furthermore, AFP expression promotes tumor growth of AFP- HCC cells i

127 At any given AFP value, low numbers of platelets and ALT and older ag

128 .001) and late stage tumours (P < 0.001) had AFP over 400 ng/ml.

129 Of the 665 LT recipients, 457 (68.7%) had AFP-producing tumors, and 208 (31.3%) had non-AFP-produc

130 Having AFP below 400 ng/ml was associated with longer survival

131 considerably between AFP+ HCC and AFP- HCC; AFP is a functional antagonist of miR-29, which may cont

132 nadensis, and demonstrate that the hemolymph AFPs are crucial for inhibiting trehalose crystallizatio

133 Of 123 patients with a high AFP level (>100 ng/dL), 12 patients achieved restored no

134 .001) and non-surgical candidates had higher AFP levels.

135 His AFP level declined rapidly after resection, and computed

136 However, 2 weeks later, his AFP level rose again, and repeat MRI of the brain showed

137 0 site was highly conserved in rat and human AFP genes, but absent in albumin genes.

138 tion of in silico models for Maxi and type I AFP binding to sII hydrates.

139 Upon immunorecognition of the immobilized AFP to its antibody, the Vio peak current decreased due

140 pe-optimization created a highly immunogenic AFP and that immunization with lentivector expressing th

141 etween fluorescence and clinically important AFP concentrations (range: 0-350 ng/mL with a correlatio

142 erimentally, we found that AFP expression in AFP- HCC cells induces cell proliferation, migration, an

143 expression and induces DNMT3A expression in AFP- HCC cells.

144 phylogenetic tree signaled prolonged gaps in AFP surveillance and a likely underreporting of polio ca

145 n the proposed method and an ELISA method in AFP and CA125 measurements of serum samples were less th

146 ificantly (P<0.001) down-regulated miRNAs in AFP+ tumors.

147 ntally regulated and plays a central role in AFP postnatal repression.

148 Our data define a cognate ZBTB20 site in AFP promoter which mediates the postnatal repression of

149 Increased AFP levels correlated with tumor growth.

150 uced changes to HVCX synapses require intact AFP output.

151 with HCC recurrence: microvascular invasion, AFP at time of LT, and the sum of the largest viable tum

152 %) had non-AFP-producing tumors (the maximum AFP level before an LT was </=10 ng/mL).

153 The midge AFP is expressed as a family of isoforms at low levels i

154 The detection limits (0.06pg/mL AFP and 0.001U/mL CA125) and linear ranges (0.2pg/mL-0.6

155 CA125) and linear ranges (0.2pg/mL-0.68ng/mL AFP and 0.003-25U/mL CA125) of this method are the same

156 of HCC, based only on 20 ng/mL and 120 ng/mL AFP, were 3.5% and 11.4%, respectively.

157 d a ZBTB20-binding site at -104/-86 of mouse AFP gene, flanked by two HNF1 sites and two C/EBP sites

158 tor expressing optimized AFP, but not native AFP, completely protected mice from tumor challenge and

159 ot produce AFP (hereafter referred to as non-AFP-producing tumors), and to identify factors influenci

160 FP-producing tumors, and 208 (31.3%) had non-AFP-producing tumors (the maximum AFP level before an LT

161 with radiographically apparent HCC have non-AFP-producing tumors that have more favorable pathologic

162 Patients with non-AFP-producing tumors also had significantly superior rec

163 Patients with non-AFP-producing tumors had radiographic tumor characterist

164 ictors of recurrence among patients with non-AFP-producing tumors include radiologic (>2 tumors [HR,

165 nsplant HCC recurrence for patients with non-AFP-producing tumors is predicted by important radiologi

166 d recurrence lowest, among patients with non-AFP-producing tumors within the Milan criteria (71% surv

167 uencing recurrence in LT recipients with non-AFP-producing tumors.

168 Nonpolio AFP rates met objectives at national and provincial leve

169 in the presence of cord blood-derived normal AFP (nAFP) or HCC tumor-derived AFP (tAFP), and DC pheno

170 41.2% (n = 160) Of patients had normal AFP level.

171 ng/dL), 12 patients achieved restored normal AFP levels (<13 ng/dL) and exhibited median overall surv

172 In addition to 12 novel AFP glycoforms, our quantification result uncovers five

173 Paradoxically, systemic accumulation of AFP-stabilized ice could also be lethal.

174 r was successfully exploited for analysis of AFP in real human blood plasma, serum and urine sample.

175 In Sokoto State, 58 cases of AFP were found from a search of 9426 households.

176 sitively correlated to the concentrations of AFP antigen.

177 rm maintenance in resource-poor countries of AFP surveillance as a platform for surveillance of vacci

178 The molecular details of AFP adsorption-inhibition is uncertain but is proposed t

179 To test the effect of AFP on DC differentiation in vitro, peripheral blood mon

180 Thus, because of the effects of AFP-induced melting inhibition, summer warming may not r

181 nted polymer was also used for estimation of AFP in the concentration range of 3.96-80.0 ng mL(-1), w

182 AFP significantly increased the frequency of AFP-specific memory CD8 T cells in the liver that were h

183 ore, AFP expression promotes tumor growth of AFP- HCC cells in nude mice.

184 ictive model that included data on levels of AFP, ALT, and platelets, along with age at time of AFP t

185 nd validated an algorithm based on levels of AFP, platelets, and ALT, along with age, which increased

186 , consistent with a more direct mechanism of AFP-mediated repression of gene expression.

187 roplanning, and management and monitoring of AFP surveillance.

188 model may be limited by the small number of AFP cases in some districts.

189 Overexpression of AFP, or conditioned media from AFP+ cells, inhibits miR-

190 onstrated that transcriptional repression of AFP gene by ZBTB20 was liver-specific.

191 r which mediates the postnatal repression of AFP gene in the liver.

192 BTB20 in vitro, as well as the repression of AFP promoter activity by ZBTB20.

193 quence-specific transcriptional repressor of AFP.

194 imilarly, the sensitivity and specificity of AFP were 62.9% and 93.3% at an ROC - derived optimum cut

195 health facilities) is a critical strategy of AFP surveillance systems for highly sensitive and timely

196 o vaccine introduction, and strengthening of AFP surveillance) that have contributed to the interrupt

197 ng Nigerian patients was higher than that of AFP for large tumours with diameter >/=3 cm.

198 99 and was significantly larger than that of AFP which was 0.85 (p < 0.001).

199 s were all significantly lower than those of AFP.

200 LT, and platelets, along with age at time of AFP test (and interaction terms between AFP and ALT, and

201 ose also enhances the antifreeze activity of AFPs.

202 ition (IRI) activity of all major classes of AFPs using cryoscopy, sonocrystallization, and recrystal

203 rowth inhibition by the different classes of AFPs: blocking fast ice growth requires rapid nonbasal p

204 tentially antagonistic pleiotropic effect of AFPs: beneficial freezing avoidance is accompanied by me

205 may help explain the long-speculated role of AFPs in freeze-tolerant species.

206 lentivector expressing the epitope-optimized AFP, but not wild-type AFP, potently activated CD8 T cel

207 zation with lentivector expressing optimized AFP, but not native AFP, completely protected mice from

208 prime-boost immunization with the optimized AFP significantly increased the frequency of AFP-specifi

209 than 10% regardless of largest tumor size or AFP.

210 reporting non-polio acute flaccid paralysis (AFP) (OR = 1.13, 95% CI 1.02-1.26 for a 1-unit increase

211 Surveillance for acute flaccid paralysis (AFP) is a fundamental cornerstone of the global polio er

212 fied with non-polio acute flaccid paralysis (AFP) reported through polio surveillance, information on

213 omplements clinical acute flaccid paralysis (AFP) surveillance for possible polio cases.

214 PEVs) isolated from acute flaccid paralysis (AFP) surveillance in Shandong Province, China from 1988

215 d information about acute flaccid paralysis (AFP) surveillance resources, training, data monitoring,

216 ntified using LAC's acute flaccid paralysis (AFP) surveillance system.

217 2009 to support the acute flaccid paralysis (AFP) surveillance system.

218 demiology of polio, acute flaccid paralysis (AFP) surveillance, and the implementation of supplementa

219 ors associated with acute flaccid paralysis (AFP) surveillance, routine immunization, and polio suppl

220 that can complement acute flaccid paralysis (AFP) surveillance.

221 A case of acute flaccid paralysis (AFP) was defined as a child <15 years of age with sudden

222 nd surveillance for acute flaccid paralysis (AFP) was suboptimal (AFP rate<1 per 100,000 population<1

223 from patients with acute flaccid paralysis (AFP) were compared by nucleotide sequencing of the VP1 c

224 ined as any case of acute flaccid paralysis (AFP) with virological confirmation of WPV1.

225 hat innervate an anterior forebrain pathway (AFP) important to feedback-dependent vocal plasticity.

226 groups of controls for each case: non-polio AFP cases ("NPAFP controls") matched to WPV1 cases by ag

227 as limited by the small numbers of non-polio AFP cases in some districts, which was reflected by larg

228 1.02-1.26 for a 1-unit increase in non-polio AFP per 100,000 persons aged <15 years).

229 te that the new fungal protease preparations AFP and FPII, bacterial protease preparation HT and the

230 fungal and bacterial protease preparations (AFP, FPII, F60K and HT) was evaluated over a range of pH

231 ng tumors or with tumors that do not produce AFP (hereafter referred to as non-AFP-producing tumors),

232 s for patients with HCCs that do not produce AFP are limited.

233 solates (HPIs) were hydrolysed by proteases (AFP, HT, ProG, actinidin and zingibain).

234 An antifreeze protein (AFP) with no known homologs has been identified in Lake

235 Since antifreeze proteins (AFPs) act as KHIs, we have used their solved x-ray cryst

236 Antifreeze proteins (AFPs) are a unique class of proteins that bind to growin

237 Antifreeze proteins (AFPs) of polar marine teleost fishes are widely recogniz

238 Antifreeze proteins (AFPs) protect certain cold-adapted organisms from freezi

239 Antifreeze proteins (AFPs), known to protect organisms from freezing by lower

240 tective capabilities of antifreeze proteins (AFPs), we hypothesized that supplementation of islets wi

241 Several ABI5/ABF binding proteins (AFPs) inhibit ABA response, resulting in extreme ABA res

242 Overexpression of ABI5/ABF binding proteins (AFPs) results in extreme ABA resistance of seeds via mul

243 Overexpression of ABI5/ABF binding proteins (AFPs) results in extreme ABA resistance of seeds via mul

244 The significance of pre-treatment AFP (pt-AFP) in non-viral HCC (nvHCC) is not clear.

245 d serum samples and in solutions of purified AFPs, and ice was found to persist inside live fishes at

246 ermore, we present the first study revealing AFP glycopeptide signatures of individual HCC patients,

247 he lungs and mediastinal nodes with a rising AFP level starting in January 2011.

248 DRC's AFP surveillance system is functional and improved durin

249 However, patients with the same AFP values (20 ng/mL and 120 ng/mL) who were 70 years ol

250 comorbidities, Child-Pugh score, BCLC, serum AFP level, and (90)Y global administered activity.

251 His serum AFP level was elevated at 47 ng/mL.

252 panel that diagnostically outperforms serum AFP.

253 group, the BCLC staging system and the serum AFP level were associated with PFS (P = 0.04) and OS (P

254 Additional interactions between some AFPs and histone deacetylase subunits were observed in y

255 , Eastern Cooperative Oncology Group status, AFP level, and PVT extent.

256 Maintaining improvements and strengthening AFP case detection at the ZS level will provide further

257 cute flaccid paralysis (AFP) was suboptimal (AFP rate<1 per 100,000 population<15 years of age) in Tu

258 tylase activity by trichostatin A suppressed AFP effects on a small fraction of the ABI5-regulated ge

259 The synthesized AFP-imprinted polymer possesses excellent selectivity to

260 hat supplementation of islets with synthetic AFP analog antiaging glycopeptide (AAGP) would enhance p

261 r proportion of ultrasound-related harm than AFP-related harm (22.8% vs. 11.4%; P < 0.001).

262 tests-more often related to ultrasound than AFP.

263 analysis in 237 HCC cases demonstrates that AFP level predicts poor survival independent of tumor st

264 Experimentally, we found that AFP expression in AFP- HCC cells induces cell proliferat

265 We found that AFP-stabilized ice resists melting at temperatures above

266 lobal DNA methylation profiling reveals that AFP+ and AFP- HCC tumors have distinct global DNA methyl

267 who would develop HCC within 6 months of the AFP test.

268 and shows preferential strong binding of the AFP to the fast growing surfaces of the sugar crystal.

269 These findings support a model in which the AFP accesses feedback independent of HVC.

270 ed to form a sandwich immunocomplex with the AFP bound to the Ab1-coated wells.

271 Z (NINJA) protein, it was suggested that the AFPs interact with the co-repressor TOPLESS to inhibit A

272 Collectively, these results suggest that the AFPs participate in multiple mechanisms modulating ABA r

273 This study shows that the AFPs that inhibit ABA response have intrinsic repressor

274 Using this AFP-adjusted model, the predictive accuracy increased at

275 ecause of the extensive resources devoted to AFP surveillance, multiple opportunities exist for addit

276 We concluded that GPC3 is inferior to AFP as a serum marker for HB.

277 of its strategic plan and as a supplement to AFP surveillance.

278 Pre treatment AFP has a limited value In diagnosing nvHCC, Having a AF

279 The significance of pre-treatment AFP (pt-AFP) in non-viral HCC (nvHCC) is not clear.

280 er for patients beyond Milan, but within TTV/AFP (16 of 38; 42.1%), than for those within Milan (49 o

281 in Milan and 38 beyond Milan, but within TTV/AFP.

282 criteria, and 32 beyond Milan but within TTV/AFP.

283 red to patients beyond Milan, but within TTV/AFP.

284 y cross-recognized short synthetic wild-type AFP peptides, but also recognized and killed tumor cells

285 and killed tumor cells expressing wild-type AFP protein.

286 the epitope-optimized AFP, but not wild-type AFP, potently activated CD8 T cells.

287 the current HCC vaccines based on wild-type AFP.

288 P was incubated in Ab1-coated wells; unbound AFP was then washed away with Tween-20.

289 s salts and alcohols, the advantage of using AFPs as an additive is that they do not alter the physic

290 rticularly in high-density populations where AFP surveillance is of poor quality, persistent virus ci

291 h data on process indicators associated with AFP surveillance and routine immunization, showing stati

292 increased DNA methylation is associated with AFP+ HCC.

293 eased at different AFP cutoffs compared with AFP alone.

294 h radiographically apparent HCC lesions with AFP-producing tumors or with tumors that do not produce

295 Patients with AFP >400 ng/mL were excluded, and, as such, the Milan gr

296 p was modified to include only patients with AFP <400 ng/mL; these patients were compared to patients

297 e, and recurrence highest, for patients with AFP-producing tumors outside the Milan criteria (40% sur

298 cteristics similar to those of patients with AFP-producing tumors, but, pathologically, they had fewe

299 uperior survival compared with patients with AFP-producing tumors.

300 s (8.8% vs 22%; P < .001) than patients with AFP-producing tumors.