ライフサイエンスコーパス: ALE

1 ALE is released as open source software under the UoI/NC

2 ALE pinpoints synthetic errors in both single and metage

3 ALE-1, a homologue of lysostaphin, is a peptidoglycan hy

4 ALE-1-targeting domain binding studies employing various

5 Unlike AGEs, very little is known about ALE effects in vitro.

6 , and accumulation of the immunoreactive AGE/ALE N( epsilon )-(carboxymethyl)lysine (CML).

7 st in part, by trapping intermediates in AGE/ALE formation and propose a mechanism for PM inhibition

8 trap reactive carbonyl intermediates in AGE/ALE formation, thereby inhibiting the chemical modificat

9 rded evidence of the key role of heme in AGE/ALE formation.

10 propose a mechanism for PM inhibition of AGE/ALE formation involving cleavage of alpha-dicarbonyl int

11 These results indicate that the AGE/ALE inhibitor PM protected against a range of pathologic

12 Our data suggest that the AGE/ALE inhibitory activity and the therapeutic effects of P

13 O and GLA and inhibited formation of the AGE/ALE N(epsilon)-(carboxymethyl)lysine during reaction of

14 uch's membrane, which is associated with AGE/ALE formation.

15 Levels of AGE/ALEs are increased in diseases like diabetes.

16 ced glycation/lipoxidation end products (AGE/ALEs).

17 ced glycation/lipoxidation endproducts (AGEs/ALEs) in 63 postmortem human donors.

18 PM, as a potent inhibitor of both AGE and ALE formation, may prove useful for limiting the increas

19 Raman spectra from a broad range of AGEs and ALEs, each with a characteristic fingerprint.

20 Pooling of results by ALE meta-analyses was stratified for population (mood di

21 essfully fabricated after one- and two-cycle ALE of the trilayer graphene, respectively.

22 Using real Pacific Biosciences data, ALE identifies 12 of 12 synthetic errors in a Lambda Pha

23 At the single-base level with Illumina data, ALE recovers 215 of 222 (97%) single nucleotide variants

24 At the genome level with real-world data, ALE identifies three large misassemblies from the Spiroc

25 Surprisingly, gene-distal ALE isoforms were four times more often localized to neu

26 have developed the Boulder ALignment Editor (ALE), which is a web-based RNA alignment editor, designe

27 ctive lead (antibacterial ligand efficiency (ALE)>0.4).

28 oci for an activation likelihood estimation (ALE) analysis.

29 conducted activation likelihood estimation (ALE) meta-analyses directly comparing the voxelwise conv

30 antitative Activation Likelihood Estimation (ALE) meta-analysis.

31 Activation likelihood estimation (ALE) was used to perform a quantitative meta-analysis of

32 f the graphene layers, atomic layer etching (ALE), a cyclic etching method achieved through chemical

33 e present an Assembly Likelihood Evaluation (ALE) framework that overcomes these limitations, systema

34 Following adaptive laboratory evolution (ALE), the knockouts increase their growth rate by up to

35 lines and found that alternative last exons (ALEs) often confer isoform-specific localization.

36 forms, incorporating alternative last exons (ALEs) that are more proximal to the transcription start

37 Binding of ALE-1 to S. aureus cells through its C-terminal 92 resid

38 d 50% identity with the N-terminal region of ALE-1 from Staphylococcus capitis EPK1.

39 hibited lysine modification and formation of ALEs during copper-catalyzed oxidation of low density li

40 hich the linkage between genomic position of ALEs and subcellular localization enables coordinated in

41 en BD-youths and BD-adults identified by our ALE meta-analyses are useful as brain-based diagnostic o

42 AGE) and advanced lipoxidation end products (ALE) in tissue proteins during aging and in chronic dise

43 otein by advanced lipoxidation end products (ALEs) during lipid peroxidation reactions in vitro.

44 n of the advanced lipoxidation end products (ALEs) N(epsilon)-(carboxymethyl)lysine, N(epsilon)-(carb

45 oducts (AGEs) and lipoxidation end products (ALEs), to protect against diabetes-induced retinal vascu

46 rom a protein-coding ASCC3 mRNA to a shorter ALE isoform of which the RNA, rather than an encoded pro

47 Synthetic ALE (malondialdehyde-lysine [MDA-Lys]) (50 micromol/l) c

48 We also conclude that ALEs derived from polyunsaturated fatty acids are increa

49 We hypothesized that ALEs can have proinflammatory effects in monocytes.

50 These new results suggest that ALEs can promote monocyte activation and vascular compli

51 The ALE-1-targeting domain belongs to the SH3b domain family

52 In this study, we demonstrated the ALE process of graphene layers without noticeably damagi

53 In summary, the ALE framework provides a comprehensive, reference-indepe

54 We believe that the ALE technique presented herein can be applicable to all

55 e false clusters better than the widely used ALE method by performing numerical experiments, and that