ライフサイエンスコーパス: AOS

1 AOS and epoxyalcohol synthase activities are mechanistic

2 AOS catalyses the production of an unstable epoxide (an

3 AOS converts 8R-hydroperoxyeicosatetraenoic acid to the

4 AOS of A. terreus appears to have evolved independently

5 AOS patients in participating centers underwent extensiv

6 AOS predisposes patients to aggressive and widespread ca

7 AOS was only observed in nfvPPA.

8 AOS, caused by pathogenic SMAD3 variants, is a recently

9 ced the jasmonate-responsive lipoxygenase 2, AOS, and AtVSP gene transcripts and induction was strong

10 We included 44 AOS patients from 7 families with pathogenic SMAD3 varia

11 tution in the P450 domain (C1073S) abolished AOS activity.

12 The roles of the main (MOS) and accessory (AOS) olfactory systems of garter snakes in response to a

13 ion that appear to be highly conserved among AOS sequences from other plants but are not conserved am

14 ene oxides, indicating that the enzyme is an AOS.

15 sing statistics of the present climate or an AOS model approximation are developed here; these formul

16 ence of etiologic continuity between COS and AOS.

17 is of etiological continuity between COS and AOS.

18 n the presence of left parietal features and AOS, and amnestic AD could be differentiated from bvFTD,

19 e SAXS data also support a model for LOX and AOS domain orientation in the fusion protein inferred fr

20 n functional distinction between the MOS and AOS is the type of sensory information processing perfor

21 ssion of pathogenesis-related genes PR1a and AOS.

22 tructures of guayule (Parthenium argentatum) AOS (CYP74A2) and its complex with the substrate analog

23 Both AOS CoMFA and CoMSIA analyses were used to construct std

24 different concentrations and may be used by AOS neural circuitry to discriminate among naturally occ

25 both necessary and sufficient for converting AOS into a GLV biosynthetic enzyme.

26 Coral AOS achieves specificity for the allene oxide formed by

27 The data indicate that cytoplasmic AOS responds to wounding by increasing the levels of the

28 the JA-isoleucine biosynthesis enzymes DDE2/AOS and JAR1 are functional.

29 is necessary for at least two very different AOS-mediated processes: basal resistance to Peronospora

30 ients have more salient genetic risk than do AOS.

31 re an additional cause of autosomal-dominant AOS or isolated ACC and provide further evidence for a k

32 RBPJ, and NOTCH1 lead to autosomal-dominant AOS.

33 ve genes (ATEG), which may code for a 9R-DOX-AOS fusion protein.

34 acalis feeding group: LOX1, ASN1, eIF3, DXS, AOS, TIM, LOX5, BBTI2, BBTI11, BBTI12, BBTI13, Cl-1B, TP

35 argeting of tomato (Lycopersicon esculentum) AOS (LeAOS) and HPL (LeHPL) to isolated chloroplasts.

36 transgenic plants constitutively expressing AOS, wound-induced JA levels were 50-100% higher compare

37 agnetic circular dichroism spectra of ferric AOS and of its cyanide and azide complexes, and the elec

38 t region for all three derivatives of ferric AOS are almost the mirror image of those in catalase.

39 transgenic tobacco plants containing a flax AOS cDNA without a chloroplast transit sequence under th

40 er, in wounded tissues overexpressing a flax AOS, levels of JA and the transcript of a pathogenesis-r

41 Induction of the flax AOS gene in transgenic plants with chlor-tetracycline (T

42 Overexpression of the flax AOS in induced transgenic plants did not increase JA lev

43 cline (Tc) led to the expression of the flax AOS mRNA and protein, which resulted in high level of me

44 lar fractionation demonstrated that the flax AOS protein and activity were associated with the cytoso

45 en compared to those not expressing the flax AOS.

46 formations is widely implicated although for AOS reactions, without direct experimental support.

47 ve genes have been identified as a cause for AOS prior to this report.

48 to find suitable ferromagnetic materials for AOS.

49 iological significance requires a functional AOS.

50 In the past, however, AOS devices required higher activation energies, and hen

51 In AOS, aspirin acetylates three serine residues near the C

52 y, ferromagnetic material is demonstrated in AOS under multiple pulses.

53 in the context of cardiovascular features in AOS-affected individuals.

54 ands showed a higher rate than that found in AOS probands (P<0.0001).

55 support a common tyrosinate-ligated heme in AOS as in catalase, significant differences exist in the

56 tide (NT-proBNP) was significantly higher in AOS patients compared with matched controls (p < 0.001).

57 oxygen bond with formation of compound II in AOS and compound I in 5,8-LDS are influenced by Asn and

58 in this pathway might also be implicated in AOS pathogenesis.

59 ide H synthase, the three serine residues in AOS are not thought to line the putative substrate chann

60 ations in the four genes with known roles in AOS pathology (ARHGAP31, RBPJ, DOCK6, and EOGT), we foun

61 zymes that was hitherto not known to include AOSs.

62 tudies provide both structural insights into AOS and related P450s and a structural basis to understa

63 to overexpression of the cytoplasm-localized AOS, while (Z)-3-hexenal and (Z)-3-hexenyl acetate appea

64 The systemic induction of LOX2, AOS, and vegetative storage protein was lower in the PLD

65 Many AOS neurons respond selectively to bile acids that are v

66 sulfated steroids, recently discovered mouse AOS ligands, caused widespread activity among vomeronasa

67 ron paramagnetic resonance spectra of native AOS (high-spin, g = 6.56, 5.22, 2.00) and of its cyanide

68 In addition, the cyanide affinity of native AOS (K(d) = 10 mM at pH 7) is about 3 orders of magnitud

69 nd identify bile acids as a class of natural AOS ligands.

70 ular cloning and characterization of a novel AOS-encoding cDNA (LeAOS3) from Lycopersicon esculentum

71 time-dependent inhibition and acetylation of AOS, which leads the irreversible inactivation of this e

72 ecular mechanisms underlying the assembly of AOS circuits critical for moving image perception.

73 in the understanding of the genetic basis of AOS, for the majority of affected subjects, the underlyi

74 tions in NOTCH1 are the most common cause of AOS and add to a growing list of human diseases that hav

75 e report the cloning and characterization of AOS (LeAOS) and HPL (LeHPL) cDNAs from tomato (Lycopersi

76 ed to identify novel genetic determinants of AOS.

77 probands, each with a clinical diagnosis of AOS.

78 e protein components operating downstream of AOS that mediate any of these processes.

79 for tyrosinate ligation to the heme iron of AOS as has been established for catalases.

80 ities of CNS are an unusual manifestation of AOS.

81 Partitioning of AOS and HPL to different envelope membranes suggests dif

82 ocognitive impairments found in relatives of AOS probands.

83 ort that mouse faeces are a robust source of AOS chemosignals and identify bile acids as a class of n

84 sults identify faeces as a natural source of AOS information, and suggest that bile acids may be mamm

85 vival and reproduction, but understanding of AOS function is limited by a lack of identified natural

86 fabrication of parallel, laterally oriented AOS nanoribbons based on lift-off and nano-imprinting.

87 lthy siblings and with adult-onset patients (AOS), carry significantly more rare chromosomal copy num

88 lthy siblings and with adult-onset patients (AOS), carry significantly more rare chromosomal copy num

89 rmation of compound II in analogy with plant AOS (CYP74) and prostacyclin synthase (CYP8A1).

90 may be a downstream target which potentiates AOS production by altering NAD(H)/NADP(H) homeostasis.

91 ally studied both single- and multiple-pulse AOS under different coupling strength between spins and

92 An information metric to quantify AOS model errors in the climate is proposed here which i

93 in EOGT and DOCK6 cause autosomal-recessive AOS, whereas mutations in ARHGAP31, RBPJ, and NOTCH1 lea

94 d N964D mutants both showed markedly reduced AOS activity, suggesting that Asn(964) may facilitate ho

95 teps by a non-polar residue markedly reduces AOS activity and, unexpectedly, is both necessary and su

96 EY1 and HES1, indicating that NOTCH1-related AOS arises through dysregulation of the Notch signaling

97 o be due to a vasculopathy in NOTCH1-related AOS.

98 ase in plant growth-promoting rhizobacteria, AOS in coral, and epoxyalcohol synthase in amphioxus.

99 ination associated with Athabasca oil sands (AOS) mining operations has on the surrounding boreal for

100 activities in Canada's Athabasca oil sands (AOS) region has led to concerns about emissions of conta

101 ) is a variant of adult-onset schizophrenia (AOS) by determining if first-degree relatives of COS pro

102 ) is a variant of adult-onset schizophrenia (AOS) by determining whether parents of COS probands show

103 cumented risk for adult onset schizophrenia (AOS), autism, epilepsy and/or ID.

104 suite of imperfect Atmosphere Ocean Science (AOS) computer models is a central issue in climate chang

105 conventional CoMFA, all orientation search (AOS) CoMFA, and CoMSIA were applied to the training sets

106 Inorganic amorphous oxide semiconductor (AOS) materials such as amorphous InGaZnO (a-IGZO) posses

107 The American Ophthalmological Society (AOS) is 1 of the 3 founding organizations of the America

108 th development of the active oxygen species (AOS) burst.

109 Active oxygen species (AOS) generated in response to stimuli and during develop

110 erest were: limb apraxia, apraxia of speech (AOS), and left parietal symptoms of dyslexia, dysgraphia

111 All-optical switching (AOS) of magnetization induced by ultrafast laser pulses

112 wo affected sibs with Adams Oliver syndrome (AOS) (OMIM 100300).

113 Adams-Oliver syndrome (AOS) is a rare developmental disorder characterized by t

114 Adams-Oliver syndrome (AOS) is a rare disorder characterized by congenital limb

115 ated individuals with Adams-Oliver syndrome (AOS), a rare disease with major features of aplasia cuti

116 families affected by Adams-Oliver syndrome (AOS), a rare multiple-malformation disorder consisting p

117 velopmental disorder, Adams-Oliver syndrome (AOS), characterized by the combination of aplasia cutis

118 pe of the aneurysms-osteoarthritis syndrome (AOS) and to provide clinical recommendations.

119 xygenase (9R-DOX) and allene oxide synthase (AOS) activities in membrane fractions.

120 We identified novel allene oxide synthase (AOS) activity and a by-product that provides evidence of

121 Allene oxide synthase (AOS) and fatty acid hydroperoxide lyase (HPL) are plant-

122 Allene oxide synthase (AOS) and hydroperoxide lyase (HPL) are related cytochrom

123 response pathway, the allene oxide synthase (AOS) and hydroperoxide lyase (HPL) branches, which are r

124 Although allene oxide synthase (AOS) and hydroperoxide lyase are atypical cytochrome P45

125 8R-Lipoxygenase and allene oxide synthase (AOS) are parts of a naturally occurring fusion protein f

126 t a cytosol-localized allene oxide synthase (AOS) can promote JA biosynthesis, transgenic tobacco pla

127 e, and the N-terminal allene oxide synthase (AOS) domain promotes the conversion of the hydroperoxide

128 rate lipoxygenase and allene oxide synthase (AOS) domains of the coral protein in Escherichia coli (B

129 Allene oxide synthase (AOS) is a cytochrome P-450 (CYP74A) that catalyzes the f

130 Allene oxide synthase (AOS) is a P450 enzyme that plays a key role in the biosy

131 but had no effect on allene oxide synthase (AOS) or hydroperoxide lyase in wounded leaves.

132 Coral allene oxide synthase (AOS), a hemoprotein with weak sequence homology to catal

133 etitive inhibitors of allene oxide synthase (AOS), the cytochrome P450 that initiates plant oxylipin

134 ynthetic gene CYP74A (allene oxide synthase, AOS) using reverse genetics screening methods.

135 This action observation system (AOS) is thought to encode neutral voluntary actions, and

136 system (MOS) and accessory olfactory system (AOS) detect and process pheromonal stimuli, yet the func

137 The accessory olfactory system (AOS) guides behaviours that are important for survival a

138 mary role of the accessory olfactory system (AOS).

139 analyzed by the accessory olfactory system (AOS).

140 n and connect to the accessory optic system (AOS) in the brain, which generates compensatory eye move

141 tic tract (NOT)--the accessory optic system (AOS) target controlling horizontal image stabilization.

142 e transmitted to the accessory optic system (AOS) where they initiate the optokinetic response.

143 nuclei termed the "accessory optic system" (AOS) generate slip-compensating eye movements that stabi

144 s summation of synaptic potentials at target AOS cells and thus provides a secondary mechanism by whi

145 e crystal structures of Arabidopsis thaliana AOS, free and in complex with substrate or intermediate

146 ncy in the aos mutant, our results show that AOS is critical for the biosynthesis of all biologically

147 lb neurons in ex vivo preparations show that AOS neurons are strongly and selectively activated by pe

148 Our results also suggest that AOS expression is limiting JA levels in wounded plants,

149 GFP, in which the RGCs projecting to all the AOS nuclei are fluorescently labeled.

150 Although the AOS domain has homology to catalase in primary structure

151 ves the noncovalent interactions between the AOS and LOX domains and suggests that the C2-like domain

152 e heme environment is largely conserved, the AOS heme is planar and the distal histidine is flanked b

153 r-considered anthropogenic PAH source in the AOS region.

154 first view of information processing in the AOS with respect to individual chemical cues.

155 is and an ionic reaction intermediate in the AOS-catalyzed transformation.

156 entration-dependent neuronal activity in the AOS.

157 fic proteolysis of the linker that joins the AOS and LOX domains.

158 For ferrimagnetic material, the AOS is attributed to magnetic circular dichroism and ang

159 The early history of the AOS and its role in the founding of the ABO are addresse

160 Here, we report the structure of the AOS domain and its striking structural homology to catal

161 Metabolism of the preferred substrate of the AOS domain, 8R-HPETE, is inhibited by the enantiomer 8S-

162 entation with constitutive expression of the AOS gene.

163 pothesize that the sustained activity of the AOS induces a new sensory state in the animal, reflectin

164 ective motor repertoire, but the role of the AOS' areas in processing affective kinematic information

165 to the medial terminal nucleus (MTN) of the AOS.

166 is required for the functional output of the AOS.

167 Here, we numerically study the AOS process and provide new insights into the long-stand

168 ng JA levels in wounded plants, but that the AOS hydroperoxide substrate levels, controlled by upstre

169 Here we investigated whether the AOS plays a role in representing dynamic emotional bodil

170 While the AOS CoMFA models gave the best internal predictions (cro

171 ygenase well suited for partnership with the AOS domain, which shows maximum rates of approximately 1

172 SGCs labeled in Hoxd10-GFP mice projected to AOS nuclei controlling horizontal but not vertical image

173 ibit other P450s that have motifs similar to AOS and consequently serve as potential biochemical targ

174 al sources in this region (i.e., unprocessed AOS bitumen, upgrader residual coke, forest fires, coal,

175 ssively shifting to the value of unprocessed AOS bitumen.

176 Screening a cohort of 52 unrelated AOS subjects, we detected 8 additional unique NOTCH1 mut

177 water oxidation system; the mixed valencies (AOS = 3.7); and the lowest charge transfer resistances (

178 types of RGCs project to each of the various AOS nuclei remain unresolved.

179 Despite the importance of signalling via AOS in eukaryotes, little is known about the protein com

180 and c.6049_6050delTC) in 2 kindreds in which AOS was segregating as an autosomal dominant trait.

181 rebellar cortical dysplasia in a family with AOS.

182 tional regulator for the Notch pathway, with AOS, a human genetic disorder.

183 earch to detect impairments in patients with AOS and ADHD and in the relatives of patients with AOS.

184 d ADHD and in the relatives of patients with AOS.

185 ressed plants than in wild-type plants, with AOS exhibiting a distinct pattern.

186 s (MAPKs) MPK3 and MPK6 after treatment with AOS or elicitor and is necessary for at least two very d