ライフサイエンスコーパス: APC resistance

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1 ist, GR144053F, inhibited platelet-dependent APC resistance.

2 ln), that has been found in association with APC resistance.

3 or pharmacologic interventions to counteract APC resistance.

4 sent in a first degree relative who also had APC resistance.

5 ffects of fibrinogen and its gamma' chain on APC resistance.

6 ew insights into the molecular mechanisms of APC resistance.

7 a new way of measuring activated protein C (APC) resistance.

8 ents with a hypercoagulable state related to APC resistance (18 women, five men; average age, 44.5 ye

9 In the general population, APC resistance and factor V Leiden were important VTE ri

10 APC resistance and increased thrombotic risk are due to

11 Patients with APC resistance and stroke appear to differ from the gene

12 s study, we have measured platelet-dependent APC resistance and the effect of aspirin and a platelet

13 It also supports the concept that APC resistance and venous thrombosis can result from a v

14 FVNara) associated with activated protein C (APC) resistance and a severe thrombotic phenotype in a y

15 Leiden, HR2 haplotype, activated protein C (APC) resistance, and plasma factor V antigen in 335 part

16 Thus, the success of the APC-resistance assay is based on the fortuitous activati

17 s assessed to be hyperhomocysteinemic showed APC resistance in a clot-based assay.

18 We observed increased APC resistance in carriers of fibrinogen gamma gene (FGG

19 atients with venous thrombosis and confirmed APC resistance in the absence of the common Gln506 mutat

20 ntrifugation at 77,000g for 1 hour abolished APC resistance indicating that the phenotype is associat

21 ic inactivation of factors Va and VIIIa, and APC resistance is often caused by factor V Leiden.

22 APC resistance measured after predilution with factor V-

23 aPC resistance of factor (f)V due to the R506Q Leiden mu

24 Activated protein C (APC) resistance, often associated with the factor V (FV)

25 The platelet-dependent APC resistance phenotype was also observed when endogeno

26 ion and modulation of the platelet-dependent APC resistance phenotype.

27 The APC resistance ratio values (ratio of activated partial

28 ase treatment of factor V did not change the APC resistance ratio.

29 Va was cleaved by APC at R506 and gave a low APC-resistance ratio similar to Q506-rFVa in clotting as

30 reas unactivated Q306-rFV gave a near-normal APC-resistance ratio.

31 including the presence of borderline or low APC resistance ratios among patients who lack the R506Q

32 account for some of the known variability in APC resistance ratios, including the presence of borderl

33 activated partial thromboplastin time-based APC resistance ratios.

34 up, a second-generation activated protein C (APC)-resistance screening test with genetic confirmation

35 Other potential causes of APC resistance, such as a mutation at the Arg679 site an

36 generation preparations have higher acquired APC resistance than users of second-generation products.

37 APC resistance was not observed in the presence of phosp

38 APC resistance was observed in the presence of platelet-

39 In platelet rich plasma (PRP), progressive APC resistance was observed with increasing platelet act

40 patient's plasma and found to induce severe APC resistance when added to normal plasma and to factor

41 to an indirect effect on platelet-dependent APC resistance with reduced platelet retention within a

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