ライフサイエンスコーパス: ASV

1 ASV pol X binds the dsDNA with a site-size of n=10(+/-2)

2 ASV with CPE gave a 20x decrease (4.0 ppb) in the detect

3 ASV-SECM can thus be used to detect and study induced di

4 2.03 +/- 9.70 vs. 12.52 +/- 7.43; p = 0.005; ASV: 12.84 +/- 10.48 vs. 13.76 +/- 8.69; p < 0.0001).

5 Comparison of the HIV-1, ASV and PFV CCD structures highlighted both conserved as

6 The avian sarcoma virus 16 (ASV 16) is a retrovirus that induces hemangiosarcomas in

7 ) in ASV versus stable or decreasing (</=2%) ASV.

8 e CRF2 receptor antagonist antisauvagine-30 (ASV-30).

9 (500 ng or 1 mug/side) or antisauvagine-30 (ASV-30; 500 ng/side) into the VTA.

10 ert in the genome of avian sarcoma virus 31 (ASV 31) and functions as the oncogenic determinant of th

11 with moderate-to-severe sleep apnea, adding ASV to OMT did not improve 6-month cardiovascular outcom

12 nd in the present study to be active against ASV IN as well as HIV-1 IN.

13 titatively the transduction efficiency of an ASV vector in naturally arrested mouse hippocampal neuro

14 l fragment of Chmp6 inhibited both HIV-1 and ASV Gag release in a dominant negative manner.

15 integration site selection of the HIV-1 and ASV integrases in opposite ways.

16 Among 9,572 patients, SD and ASV were significantly lower with atorvastatin 80 mg/day

17 ate stable interactions between HMG-I(Y) and ASV IN or between HMG-I(Y) and HIV-1 IN.

18 ith (n = 3) or without (n = 13) asunaprevir (ASV; PI).

19 nts were not significantly different between ASV and control.

20 against both IN proteins was shown to block ASV IN DNA binding and end fraying, with similar dose re

21 ttle effect on HIV-1 Gag release but blocked ASV Gag release.

22 transcription factors HNF3 and GATA4 blocked ASV DNA integration in extended nucleosome arrays, local

23 rcoma virus genome, precise deletion of both ASV dr1 elements results in a very low level of virus re

24 each 1-SD increase in LDL-C variability (by ASV) increased the risk of any coronary event by 16% (ha

25 HIV-1 IN conferred partial ability to cleave ASV substrates with a concomitant loss in the ability to

26 For conducting ASV on-line with ICPMS, the DIHEN was found to be more a

27 (Hg-GC) electrodes were compared for the CPE-ASV.

28 with cirrhosis; 1 had previously failed DCV-ASV plus Peg-IFN and RBV).

29 to the analysis in complex matrices, duplex ASV-QDs-based determination of bovine casein and bovine

30 The ECVDEP was also normalized as the ECV/ASV ratio.

31 oanalytical tools cannot efficiently examine ASV and PTM events simultaneously, which limits understa

32 mid acceptor, purified bacterially expressed ASV integrase (IN), and human high-mobility-group protei

33 with the pH vs activity profile observed for ASV IN.

34 ults are consistent with a possible role for ASV IN in nuclear targeting.

35 ion of the LTR termini, the amino acids from ASV IN were substituted into the structurally equivalent

36 behaviour of sucrose has been discussed from ASV and ASIC parameters, as these parameters, which are

37 However, viral reporter gene expression from ASV-based vectors was substantially higher in the Daxx-n

38 the proteolytic degradation of GFP[AAV], GFP[ASV], and GFP[LVA], which are popular variants of GFP wi

39 was determined as interval increase (>2%) in ASV versus stable or decreasing (</=2%) ASV.

40 These results suggest the dr1 elements in ASV act to selectively inhibit src splicing and that bot

41 Daxx was not required for early events in ASV replication, including integration, as Daxx-null cel

42 endoleaks, there was an interval increase in ASV.

43 surements in indicating interval increase in ASV.

44 s can substitute for Nedd4 family members in ASV Gag release.

45 the chromosomal features that may influence ASV integration and support the idea that distinct, viru

46 ore domain of avian sarcoma virus integrase (ASV IN) have provided the most detailed picture so far o

47 ore domain of avian sarcoma virus integrase (ASV IN) were solved at 1.9- to 2.0-A resolution at two p

48 is included 323 proteoforms for the 14.1 kDa ASV alone.

49 d, and stearic acid at C78 of the 17.125 kDa ASV.

50 cterization workflow resolved four known MBP ASVs and hundreds of differentially modified states from

51 merican Society for Virology Annual Meeting (ASV), the International Herpesvirus Workshop (IHW), the

52 Using a modified ASV encoding a murine leukemia virus amphotropic env gen

53 CAT-HF (Cardiovascular Improvements With MV-ASV Therapy in Heart Failure) trial investigated whether

54 In the structures of native ASV IN at pH 6.0 and below, as well as in all structures

55 ted at low pH for the crystals of the native ASV IN core domain.

56 We also identified two novel ASVs from an alternative transcriptional start site (ATS

57 ffusion phenomena may relate to the observed ASV-SECM behavior.

58 roup analysis suggested a positive effect of ASV in patients with HF with preserved ejection fraction

59 nals and identifying differential effects of ASV in patients with HF with preserved ejection fraction

60 d efficient accumulation of nuclear forms of ASV DNA in gamma-irradiation-arrested cells.

61 Translational fusion of ASV Gag with an L domain deletion (Deltap2b) to proteins

62 rming that nuclear import and integration of ASV DNA can occur in the absence of mitosis.

63 mitosis in nuclear import and integration of ASV DNA.

64 cells revealed that the expression levels of ASV target genes were similar to the median level for al

65 integration, underscoring the preference of ASV for compacted chromatin.

66 To identify the region of ASV IN that specifies nuclear localization, various subd

67 on is necessary for efficient replication of ASV in culture.

68 tacts with the LTRs and that substitution of ASV IN amino acids at many of the analogous positions in

69 oding genes) appear to be favored targets of ASV integration.

70 ool of Vps37C (ESCRT-I) had little effect on ASV but blocked HIV-1 Gag release.

71 lear import mechanism for the oncoretrovirus ASV and suggest that this mechanism can operate in both

72 y of the chimeras to 3 ' process U5 HIV-1 or ASV duplex oligos was determined.

73 We found no evidence for preferred ASV integration sites over the length of genes and immed

74 nd end fraying, with similar dose responses; ASV IN substitutions that reduced DNA binding also reduc

75 In addition, a single ASV-SECM image is shown to produce unique concentration

76 The results found pointed out that both SW-ASV approaches were suitable and easy-to-use method to m

77 square wave anodic stripping voltammetry (SW-ASV) conducted at both solid gold electrode (SGE) and a

78 The resultant hyphenated technique (ASV-DIHEN-ICPMS) is capable of analyzing select heavy me

79 was also found to be required for long-term ASV silencing maintenance and full viral DNA methylation

80 Taken together, these results indicate that ASV and HIV-1 Gag utilize different combinations of ESCR

81 The results indicate that ASV is able to transduce these differentiated neurons ef

82 Lastly, we observed that ASV can transduce postmitotic mouse neurons.

83 Here we report that ASV integrase (IN) expressed as a fusion to beta-galacto

84 int did not differ significantly between the ASV and control groups (p = 0.92 Wilcoxon).

85 ased from 35.7/h to 2.1/h at 6 months in the ASV group versus 35.1/h to 19.0/h in the control group (

86 Analysis of the ASV 16 genome revealed that it encodes an oncogene that

87 The transduction efficiency of the ASV vector was found to be intermediate between the rela

88 These analyses showed that the ASV IN protein possesses a functional nuclear localizati

89 We have used the ASV and HIV-1 reconstituted systems to compare the mecha

90 (4.0 ppb) in the detection limit compared to ASV without CPE.

91 In contrast to ASV Gag, HIV-1 Gag containing an L domain inactivating m

92 DGT measured similar labile fractions to ASV, with detailed differences being consistent with a t

93 ate-to-severe sleep apnea were randomized to ASV plus optimized medical therapy (OMT) or OMT alone (c

94 ng dimer" previously described for wild type ASV apoIN and resembles the inner, substrate binding dim

95 e mutant of Vps4 ATPase similar to wild type ASV Gag.

96 of the U5 ASV substrate closer to wild type ASV IN compared with chimeras with individual amino acid

97 Unlike wild type, ASV Gag/Deltap2b -ESCRT chimeras failed to co-immunoprec

98 s showed a specificity of cleavage of the U5 ASV substrate closer to wild type ASV IN compared with c

99 as induced in an interferon-like manner upon ASV infection.

100 The results obtained using ASV are in good agreement with reference values using co

101 ability: SD, average successive variability (ASV), coefficient of variation, and variation independen

102 pression of two alternative splice variants (ASV), which differ in length and in the exon/intron rete

103 y with numerous alternative splice variants (ASVs) and post-translational modifications (PTMs) report

104 or suspected alternative splicing variants (ASVs) using PCR, primer extension and matrix-assisted la

105 ventilation (MV) adaptive servo-ventilation (ASV) improved cardiovascular outcomes in hospitalized HF

106 of catalysis with both avian sarcoma virus (ASV) and human immunodeficiency virus type 1 (HIV-1) IN

107 of integrase (IN) from avian sarcoma virus (ASV) and its active-site derivative containing an Asp64

108 epeat elements (dr1) of avian sarcoma virus (ASV) and leukosis virus have the properties of constitut

109 y virus type 1 (HIV-1), avian sarcoma virus (ASV) and their close orthologs from the Lentivirus and A

110 have demonstrated that avian sarcoma virus (ASV) can transduce cycle-arrested cells.

111 scribed a reconstituted avian sarcoma virus (ASV) concerted DNA integration system with specially des

112 a model system in which avian sarcoma virus (ASV) DNA is epigenetically repressed in mammalian cells,

113 es bind the L domain in avian sarcoma virus (ASV) Gag and facilitate viral particle release.

114 everse transcription in avian sarcoma virus (ASV) initiates from the 3' end of a tRNA(Trp) primer, wh

115 arcoma virus (SIV), and avian sarcoma virus (ASV) INs predicted which of these residues were unique.

116 d as an interactor with avian sarcoma virus (ASV) integrase (IN) in a yeast two-hybrid screen.

117 nd shape of full-length avian sarcoma virus (ASV) integrase (IN) monomers and dimers in solution usin

118 al region of the 286-aa avian sarcoma virus (ASV) integrase (IN) protein has been shown previously to

119 ontrast, integration by avian sarcoma virus (ASV) integrase was more efficient after compaction by ei

120 port the mapping of 226 avian sarcoma virus (ASV) integration sites in the human genome.

121 he process by which the avian sarcoma virus (ASV) preintegration complex gains access to target chrom

122 reviously described for avian sarcoma virus (ASV) that was stimulated by the presence of HMG-1.

123 n of an oncoretrovirus, avian sarcoma virus (ASV), suggesting an active import mechanism for the inte

124 silencing of integrated avian sarcoma virus (ASV)-based vector DNAs in human HeLa cells.

125 the simple retrovirus, avian sarcoma virus (ASV).

126 simultaneous anodic stripping voltammetric (ASV) determination of Pb(II) and Cd(II) at the bismuth n

127 determined by anodic stripping voltammetry (ASV) after transferring the gold microelectrode in an aq

128 ontrast, while anodic stripping voltammetry (ASV) also revealed five peaks, peak identification was n

129 ter to perform anodic stripping voltammetry (ASV) at a thin mercury film followed by subsequent ICPMS

130 nce (SPR) with anodic stripping voltammetry (ASV) capability has been demonstrated for detecting heav

131 For anodic stripping voltammetry (ASV) of Pb, our sensor shows 21 nM (4.4 ppb) limit of de

132 Anodic stripping voltammetry (ASV) performed at Hg/Pt UMEs displayed a linear response

133 ying fast-scan anodic stripping voltammetry (ASV) to provide sensitive and selective imaging of multi

134 roscopy (AAS), anodic stripping voltammetry (ASV), and DGT.

135 n required for anodic stripping voltammetry (ASV), so cathodic stripping voltammetry (CSV) has been s

136 metal ions by anodic stripping voltammetry (ASV).

137 metal ions by anodic stripping voltammetry (ASV).

138 oelectrode and anodic stripping voltammetry (ASV).

139 um (Cd(2+)) by anodic stripping voltammetry (ASV).

140 n determined from apparent specific volumes (ASV) data at 20-45 degrees C and 0.04-0.89 mol kg(-1).Th

141 lumes, V2,varphi, apparent specific volumes, ASV, apparent molar isentropic compressibilities, Ks,2,v

142 tone deacetylases (HDACs) can associate with ASV DNA soon after infection and may act to repress vira

143 rated HNO3/30% H2O2 mixture, compatible with ASV and the iridium electrode.

144 Pre-treatment with ASV-30 blocked these effects.

145 While complexes containing HMG-I(Y), ASV IN, and donor DNA can be detected in gel shift exper