ライフサイエンスコーパス: AT

1 AT burden was highest in complex CHD, such as single ven

2 AT couplon "super-hubs" thus underlie faster excitation-

3 AT significantly reduced lung expression of CCN1 and alt

4 AT termination rates for distributed illumination were l

5 AT-RvD1-treated mice had lower total cell counts and neu

6 DNA sequences with base composition of 100% AT, 80% AT and 100% GC in the presence of [Ru(NH3)6]3(+)

7 at they carried the FTO risk allele (level 3 AT/AA carriers) than in the nonpersonalized group (level

8 in a side-by-side orientation to RF where 3 AT-hooks act as a clamp to wrap around a distorted RF.

9 METHODS AND We prospectively studied 33 AT (post- atrial fibrillation ablation or surgical mitra

10 d (5802 FineVision in 2901 patients and 4282 AT Lisa in 2141 patients).

11 ss the P. falciparum reference genome (80.6% AT).

12 In 32/49 (67%) ATs, electrograms were nonfractionated, and <50% of tach

13 mitochondrial DNA (kDNA), comprising of >70% AT base pairs.

14 uences with base composition of 100% AT, 80% AT and 100% GC in the presence of [Ru(NH3)6]3(+) as a re

15 pants were stratified into risk carriers (AA/AT) and nonrisk carriers (TT) of the FTO gene for analys

16 However, use of a standalone trans-acting AT to complement modules with catalytically deficient AT

17 -month mean (+/- standard deviation) acuity: AT Lisa, binocular uncorrected distance visual acuity (U

18 that inactivation of a cis-acyltransferase (AT) domain to circumvent its native extender unit prefer

19 In addition, AT-RvD1-treated mice showed changes in temporal regulati

20 basic patch and that the BRD and an adjacent AT-hook make multivalent contacts with DNA, leading to r

21 associations between rigorously adjudicated AT/AF and predefined clinical events, including stroke.

22 However, AF/AT was associated with a borderline decreased risk of mo

23 Postrandomization AF/AT was associated with risk of heart failure hospitaliza

24 In adjusted models, postrandomization AF/AT was not associated with the primary outcome (hazard r

25 Postrandomization AF/AT, which remained paroxysmal in 69.5%, did not reduce b

26 nction with raised auditory thresholds after AT.

27 eatment with the potent NOP receptor agonist AT-202 (0.3-3 mg/kg) increased nicotine lever pressing o

28 amilies allatostatin A (AstA), allatotropin (AT), short neuropeptide F (sNPF), and tachykinin (TK) as

29 entrainment pathways, whereas allatotropin (AT) only delayed locomotor rhythms at the early night.

30 In mouse AM, AT structures triggered Ca2+ release from the SR approxi

31 -amino butyric acid (GABA)-aminotransferase (AT) inhibitor, shows comparable pharmacokinetics, improv

32 BD) harboring the conserved CENP-C motif, an AT hook, and RK clusters (clusters enriched for arginine

33 response calculations, and experiments on an AT-sequence, we show that the ICD of minor-groove-bound

34 nucleoid-associated protein that binds to an AT-rich conserved DNA sequence motif and regulates both

35 oleoresins improved the stability of AX and AT to a greater extent in oleoresins with a monounsatura

36 around the dwarf novae Z Camelopardalis and AT Cancri, but direct evidence for considerable mass-tra

37 triking interplay between leukemic cells and AT to create a unique microenvironment that supports the

38 on with serum total and LDL cholesterol, and AT lipidomics.

39 The DT and AT networks were distinct for each tissue type, with no

40 the pituitary, suggesting that locally- and AT-produced adipokines might comprise a regulatory circu

41 exposure in male Wistar rats' metabolism and AT biology, assessing a range of metabolic, biochemical

42 , and phosphorylated tau (AT-270 pThr181 and AT-180 pThr231).

43 e dyad, engaging with both Cse4 residues and AT-rich nucleosomal DNA.

44 Lovaza treatment restored AT-RvD3 and AT-LXB4 and gave levels of RvD6 and aspirin-triggered pr

45 a demonstrate protective actions of RvD3 and AT-RvD3 for injured mucosa that accelerated restoration

46 r counterregulation of NF-kappaB by RvD3 and AT-RvD3 was seen in vitro and by AT-RvD3 in vivo.

47 insulin resistance, metabolic syndrome, and AT inflammation.

48 Antithrombin (AT) is an anticoagulant serpin that irreversibly inactiv

49 a homologous aspartate aminotransferase (Asp-AT) from Escherichia coli as a control.

50 uctures of the Eb/O-PLP-AFPA complex and Asp-AT-PLP-AFPA complex revealed that GabR is incapable of f

51 Immunofluorescence staining against AstA, AT, and TK in the brain revealed arborizations of AstA-

52 on of highly phosphorylated RyR2 clusters at AT-SR junctions and earlier, more rapid shortening of ce

53 (Lin-/Sca+/c-Kit+; LSK phenotype) in the AT (AT-LSK) has been reported.

54 ently slowed or suppressed 100% of automatic ATs.

55 enomes exhibited similar AT nucleotide bias, AT-, GC-skews and codon usage.

56 nsplantation of control AT-LSK improves both AT-inflammation and glucose homeostasis in HFD mice.

57 Overall, both AT and EZT attenuated diabetic nephropathy; however, AT

58 brown AT mass (5.96 versus 4.50 mg/g), brown AT showed reduced activity with decreased uncoupling pro

59 In HFpEF, despite a larger brown AT mass (5.96 versus 4.50 mg/g), brown AT showed reduced

60 by RvD3 and AT-RvD3 was seen in vitro and by AT-RvD3 in vivo.

61 ruited to infected wounds were unaffected by AT production and were activated to expand PMN numbers i

62 nsin II receptor type 1 (AGTR1), in the Ca2+/AT-IIR/alpha-AR signaling pathway.

63 de substitution, which would naturally cause AT content to equilibrate close to the level seen across

64 RBP4 elevation causes AT inflammation by activating innate immunity, which eli

65 e pairing leading to ejection of the central AT bases, while placing the proreactive centers of 1 in

66 ibility of nucleosome linkers in the compact AT-IN arrays.

67 hat the Ml proteins studied bind a conserved AT-rich site in the promoter region of the exoY gene fro

68 In contrast, AT-OUT nucleosome arrays formed less compact structures

69 Conversely, the transplantation of control AT-LSK improves both AT-inflammation and glucose homeost

70 target in each individual (i.e. the critical AT isthmus).

71 of RvD6 and aspirin-triggered protectin D1 (AT-PD1) twice as high (resolvin E2 approximately 5 fold)

72 thesized that aspirin-triggered resolvin D1 (AT-RvD1) would dampen NTHi-induced inflammation while st

73 plement modules with catalytically deficient AT domains leads to enzyme acylation with the fluoromalo

74 Independent risk factors for developing AT were univentricular physiology, previous intracardiac

75 Mutations in known cancer drivers AT-rich interaction domain 1A (ARID1A) and BRCA1 associa

76 The interactions of these processes during AT expansion reflect both a linear progression as well a

77 For each AT, 25 684+/-14 276 EGMs were automatically annotated.

78 ggests that for the NOP receptor, the entire AT-076 scaffold is crucial for high binding affinity, bu

79 models, we attempted to terminate re-entrant AT (induced via rapid pacing) via optogenetic stimulatio

80 ntified larger B-cell clusters in epicardial AT of human patients with coronary artery disease in com

81 ymphoid clusters were examined in epicardial AT of humans with or without coronary artery disease.

82 inical outcomes remains unclear.We evaluated AT transcriptome alterations during an LCD and the assoc

83 articular attention because of their extreme AT-content.

84 e of atrial tachycardia and/or fibrillation (AT/AF) of any duration in patients with pacemakers and i

85 Finally, AT-RvD1 decreases lymphocytic infiltration into the sali

86 the time lapse between surgery and the first AT episode varied among the most common CHD.

87 ably identifies specific mechanisms of focal AT.

88 Absence of adenosine effect on focal AT identifies tachycardia due to microreentry.

89 The remaining 17 focal ATs had localized fractionated electrograms (>/=35% of t

90 at remote contact frequencies are higher for AT-rich and methylated DNA, suggesting that direct DNA-D

91 pid to lysosomes in ATMs and is required for AT homeostasis.

92 robust affinity and moderate specificity for AT-rich elements.

93 panel of 11 proteins to distinguish CRC from AT.

94 with the E-cadherin promoter in kidneys from AT-, relative to EZT- or vehicle-treated rats.

95 Furthermore, AT from obese mice exhibits an increased sensitivity to

96 mma-aminobutyric acid aminotransferase (GABA-AT; GabT) upon interactions with pyridoxal-5'-phosphate

97 concentration indicates the reversible GABA-AT resynthesis following drug washout.

98 Elevated expression of high-mobility group AT hook 2 (HMGA2) has also been frequently observed in p

99 tin architectural factor High Mobility Group AT-hook 1 (HMGA1) in pulmonary arterial endothelial cell

100 eta-catenin coactivator, high-mobility group AT-hook 1 protein (HMGA1), was detected in significantly

101 eta-catenin coactivator, high-mobility group AT-hook 1 protein (HMGA1), was readily detected in a sub

102 High mobility group AT-hook 2 (HMGA2) protein is composed of three AT-hook d

103 netic drivers, including high mobility group AT-hook 2 (HMGA2) rearrangements, mediator complex subun

104 ; high lin-28 homolog B, high mobility group AT-hook 2, spalt-like transcription factor 4, and alpha-

105 trand- and sequence-context-dependent GC --> AT transitions.

106 LD1-R689W are GC-->TA transversions and GC-->AT transitions, with transversions showing a strong stra

107 In conclusion, high AT content in P. falciparum is driven by a systematic mu

108 falciparum genome has an exceptionally high AT content compared to other Plasmodium species and euka

109 pted a nucleoid-associated protein with high AT recognition to serve as a mediator of cell cycle prog

110 proteins bind incoming DNA that has a higher AT content than the host genome.

111 ences flanking the binding peak had a higher AT nucleotide content, implying that broader DNA structu

112 nd preferentially to DNA sequences of higher AT content.

113 Significantly higher AT-content in sequences of the same species was also obt

114 However, AT was significantly more effective than EZT at reducing

115 ZT attenuated diabetic nephropathy; however, AT exhibited greater efficacy despite a similar reductio

116 ventions led to decreased TSHB mRNA in human AT, whereas excess cholesterol up-regulated TSHB mRNA in

117 arallel with cholesterol metabolism in human AT.

118 Here, we identified AT-rich interactive domain 5B (ARID5B) as a collaboratin

119 In AT, T. cruzi resides inside adipocytes, T. brucei is fou

120 Given that obesity increases autophagy in AT and contributes to lipid catabolism in other cells, i

121 NAseq), we analyzed transcriptome changes in AT from 191 obese, nondiabetic patients within a multice

122 TSHB mRNA was consistently detected in AT from euthyroid subjects, and positively associated wi

123 fatty acids (FAHFAs), which were elevated in AT and serum of AG4OX mice.

124 (Il4ra) and its ligand IL-13 are elevated in AT of obese C57BL/6 mice.

125 fection with wild-type S. aureus enriched in AT reduced PMN recruitment and resulted in sustained bac

126 bolic properties, are strikingly enriched in AT, and are protected from chemotherapy by the GAT micro

127 Activation of hepatic mTOR in AT mice decreased lipid accumulation attenuated HIRI as

128 he mechanisms of immunometabolic response in AT from cancer cachexia.

129 In 97% of AT, ablation at the CI resulted in AT termination.

130 lied to a fragment-derived lead resulting in AT-IAP, a potent, orally bioavailable, dual antagonist o

131 nt and glucose intolerant and have increased AT macrophages and T-helper 1 cells.

132 tors, their addition progressively increased AT burden.

133 69, 0.92; P = 0.058).This study investigated AT transcriptome alterations after an LCD in a large coh

134 in the nucleosome linkers to induce inward (AT-IN) and outward (AT-OUT) bending of the linker DNA.

135 ruitment to wounds infected with an isogenic AT-deficient S. aureus strain was unimpeded, exhibiting

136 The mesenteric AT (MeAT) was collected on d 0, 4, 7 (early stage), and

137 ed alkanethiolate self-assembled monolayers (AT SAMs) and, furthermore, by up to 2 orders of magnitud

138 It colocalized GABA and MIP but not AT or ORC immunoreactivity.

139 Up to now, AT macrophages (ATM) accumulation was considered to be d

140 In 97% of AT, ablation at the CI resulted in AT termination.

141 Lipidomic analysis of AT identified a structurally unique class of lipids, bra

142 optogenetic stimulation based on analysis of AT morphology may be a reliable approach for defibrillat

143 tical determinant of the clinical benefit of AT.

144 our SAR analysis of the common chemotype of AT-076 suggests rational approaches to modulate binding

145 we established organotypic cell cultures of AT explants to study the impact of cytokine treatment on

146 the accumulation of DNA in the cytoplasm of AT and Artemis-deficient cells.

147 s low noise and allows accurate diagnosis of AT circuits.

148 We recently reported the discovery of AT-076 (1), (R)-7-hydroxy-N-((S)-1-(4-(3-hydroxyphenyl)p

149 50% of patients had at least one episode of AT/AF.

150 riate clinical response to brief episodes of AT/AF remains unclear.

151 Only short episodes of AT/AF were documented in 9% of pacemaker patients and 16

152 We show that exposure of AT to Th2 cytokines, such as IL-4, IL-13, and GM-CSF, st

153 chniques, we observed spontaneous folding of AT-IN nucleosome arrays into highly compact structures,

154 Consequently, haploinsufficiency of AT-1/SLC33A1 in the mouse rescued Alzheimer's disease, b

155 Natural history of AT differed among the most common forms of CHD.

156 RNA polymerase that diminished the impact of AT-rich DNA on host fitness reduced transcription from c

157 on of adipose tissue (AT) and an increase of AT macrophages (ATMs) that is linked to the onset of typ

158 In vivo induction of AT at around P20 disrupted IPSC and EPSC integration in

159 Our results justify further investigation of AT with kinase inhibitors.

160 In vitro, sublytic levels of AT impaired uptake of apoptotic neutrophils by purified

161 ndent manner required for the maintenance of AT; deficiency in lysosomal acid lipase (Lipa), the enzy

162 tes the incidence and clinical predictors of AT in a cohort of patients with CHD.

163 vasive means, were independent predictors of AT in adults with CHD.

164 Predictors of AT were identified by multivariable Cox regression analy

165 In vivo, the presence of AT reduced uptake of neutrophils by AMs.

166 loA promoter region revealed the presence of AT-rich direct and inverted repeats previously reported

167 Hazard rates of AT across lifetime, age at presentation, and the time la

168 Caulobacter, suggesting that recognition of AT-rich DNA is not sufficient for the asymmetric accumul

169 lizing effects of mutations in the region of AT that makes contact with the proteinase in the final a

170 e Delphian lymph node in different stages of AT were evaluated.

171 Here, we showed that the toxicity of AT-rich DNA in Escherichia coli frequently results from

172 Transplantation of AT-LSK sorted from high fat diet-fed (HFD) mice is suffi

173 fects of statins and of diet and exercise on AT TSHB mRNA were also examined.

174 atio for patients with the rs139550538 AA or AT genotype was 1.61 (95% CI, 1.38-1.89; P = 1.87 x 10-9

175 sion Micro F (PhysIOL SA, Liege, Belgium) or AT Lisa tri 839MP (Carl Zeiss AG, Jena, Germany).

176 inkers to induce inward (AT-IN) and outward (AT-OUT) bending of the linker DNA.

177 In RBP4-Ox, AT macrophages display enhanced c-Jun N-terminal kinase,

178 in CB2(-/-) mice were limited by pericardial AT removal.

179 Leukocytes in murine hearts, pericardial AT, spleen, mediastinal lymph nodes, and bone marrow wer

180 h higher DC and T-cell counts in pericardial AT, which outnumbered DCs and T cells in lymph nodes.

181 d DCs migrate from infarcts into pericardial AT via CCR7.

182 ects was confirmed by removal of pericardial AT and ex vivo coculture with pericardial AT and granulo

183 ndritic cell (DC) trafficking on pericardial AT inflammatory responses was tested in CCR7(-/-) mice s

184 er MI, we surgically removed the pericardial AT and performed B-cell depletion and granulocyte-macrop

185 eil a new mechanism by which the pericardial AT coordinates immune cell activation, granulopoiesis, a

186 The relevance of the pericardial AT in mediating all these effects was confirmed by remov

187 al AT and ex vivo coculture with pericardial AT and granulocyte progenitors.

188 d DC and T-cell expansion within pericardial AT, and translated into reduced bone marrow granulopoies

189 factor-producing B cells within pericardial AT, but not spleen or lymph nodes.

190 Like previously identified PGX1(AT) plants, PGX2(AT) plants have longer hypocotyls and l

191 GX2-GFP localizes to the cell wall, and PGX2(AT) plants show higher total polygalacturonase activity

192 corresponding activation tagged line as PGX2(AT) .

193 previously identified PGX1(AT) plants, PGX2(AT) plants have longer hypocotyls and larger rosette lea

194 Overall, 153 (4.6%) patients presented AT.

195 we have identified a novel cellular protein (AT-rich interacting domain protein 3B [ARID3B]) that we

196 infiltration) were reduced in mice receiving AT-RvD3 1 hour after injury.

197 For reentrant AT, within the CI, bipolar EGM amplitude (0.08+/-0.11 mV

198 CI on reentrant scar-related AT showed much lower EGM amplitude with a significantly

199 pecies, primarily associated with repetitive AT-rich sequences, in addition to larger-scale structura

200 g metabolic disease, originate from resident AT-LSK.

201 ur results clearly demonstrate that resident AT-LSK are one of the key point of metabolic disease, an

202 Lovaza treatment restored AT-RvD3 and AT-LXB4 and gave levels of RvD6 and aspirin-

203 ntive treatment with Aspirin-triggered RvD1 (AT-RvD1) reduces inflammation and preserves secretory fu

204 When we attempted to terminate the same AT episodes with targeted illumination, outcomes were si

205 gh their N-terminal region and that the same AT-rich site is recognized by MucR from Brucella abortus

206 Cross-sectionally, AT TSH-beta (TSHB) mRNA was evaluated in 4 independent c

207 nce of the time of the day for how sensitive AT is to the effects of insulin.

208 more likely than those without to have short AT/AF (5.1% vs. 7.9% for pacemaker patients and 11.5% vs

209 All three mitogenomes exhibited similar AT nucleotide bias, AT-, GC-skews and codon usage.

210 Since AT-076 binds with high affinity at all four subtypes, we

211 By using transplantation of sorted AT-LSK and gain and loss of function studies we show tha

212 e found that the chromatin organizer special AT-rich sequence-binding protein-1 (Satb1) restrains PD-

213 In mice, subcutaneous AT Tshb expression levels correlated directly with circu

214 UCP1 and beige adipogenesis of subcutaneous AT in obesity.

215 ch may adhere to the blood vessels supplying AT.

216 ally differentiate focal atrial tachycardia (AT) caused by microreentry, triggered activity, or enhan

217 efficacy of optogenetic atrial tachycardia (AT) termination in human hearts using a strategy that ta

218 togenetic termination of atrial tachycardia (AT), comparing two different illumination strategies: di

219 reentrant scar-related atrial tachycardias (AT) allows efficient radiofrequency ablation by targetin

220 Atrial tachycardias (ATs) are a significant source of morbidity in adults wit

221 teins Iba1 and CD68, and phosphorylated tau (AT-270 pThr181 and AT-180 pThr231).

222 commonly observed in ataxia telangiectasia (AT) and Artemis deficiency.

223 Ten ATs had nonfocal activation, with >/=90% of tachycardia

224 rameters included normalized active tension (AT (norm)) and active tension at the resting sarcomere l

225 ength can efficiently and reliably terminate AT if the human atria can be successfully light-sensitiz

226 ength can efficiently and reliably terminate AT in atria light-sensitized via gene delivery.

227 We conclude that AT-induced IL-1beta promotes local granulopoiesis and ef

228 rive matures to identical time-courses, that AT changes synaptic AMPARs by expression of subunits wit

229 Strikingly, we also discovered that AT-rich centromere DNA has an important role for Mif2 re

230 Our findings suggest that AT and ClfA are pathogenic factors that could be therape

231 essfully generate HEK293T cells carrying the AT genotype at the first SNP - rs4073 (alias -251), TT g

232 lls (Lin-/Sca+/c-Kit+; LSK phenotype) in the AT (AT-LSK) has been reported.

233 ovide evidence that 6mA occurs mostly in the AT motif of the linker DNA regions.

234 ation and closer nucleosome proximity in the AT-IN arrays due to inward linker DNA bending.

235 Haploinsufficiency of the AT-rich interactive domain 1B (ARID1B) gene causes autis

236 ow that light pulses lasting longer than the AT cycle length can efficiently and reliably terminate A

237 argeted light pulses lasting longer than the AT cycle length can efficiently and reliably terminate A

238 strongly and positively correlated with the AT content of the underlying DNA sequence.

239 f FANCD2, replication forks stall within the AT-rich fragility core of CFS, leading to dormant origin

240 Adaptive therapy (AT) aims to control tumour burden by maintaining therapy

241 Adenosine had no effect in these ATs.

242 -hook 2 (HMGA2) protein is composed of three AT-hook domains.

243 ic low-grade inflammation of adipose tissue (AT) and an increase of AT macrophages (ATMs) that is lin

244 ), are bioaccumulated in the adipose tissue (AT) and have been implicated in the obesity and diabetes

245 body weight loss, atrophy of adipose tissue (AT) and systemic inflammation.

246 inflammatory macrophages, in adipose tissue (AT) are deleterious in metabolic diseases.

247 The pericardial adipose tissue (AT) contains a high density of lymphoid clusters.

248 ulin sensitivity, and alters adipose tissue (AT) gene expression, yet the relation with clinical outc

249 Adipose tissue (AT) has previously been identified as an extra-medullary

250 athogenesis of dysfunctional adipose tissue (AT) in obesity: unresolved inflammation, inappropriate e

251 Adipose tissue (AT) inflammation contributes to impaired insulin action,

252 esity, inflammation of white adipose tissue (AT) is associated with diminished generation of beige ad

253 Adipose tissue (AT) is no longer regarded as an inert lipid storage, but

254 Adipose tissue (AT) macrophages (ATMs) contribute to obesity-induced inf

255 Adipose tissue (AT) regulates systemic insulin sensitivity through multi

256 lesterol metabolism in human adipose tissue (AT).

257 Adipose-tissue (AT) is an endocrine organ that dynamically secretes mult

258 gmoid colon tissue (DT) and adjacent tissue (AT) from the same colonic segment.

259 lysis of paired tumors and adjacent tissues (AT) using high-resolution Fourier-transform mass spectro

260 Dlx-containing regulatory complexes bound to AT-rich motifs.

261 degree of overexpression in CRC compared to AT was Dipeptidase 1 (DPEP1).

262 um, causing further enhancement of the GC to AT bias characteristic of organisms with normal MMR func

263 of autophagy in macrophages does not lead to AT atrophy or alter metabolic phenotypes in lean or obes

264 ired for lysosome lipid catabolism, leads to AT atrophy and severe hepatic steatosis, phenotypes resc

265 AX and alpha-tocopherol (AT) degradation followed a zero-order and first-order ki

266 f the secreted virulence factor alpha toxin (AT), which has been implicated in altering the antimicro

267 n monoclonal antibodies against alpha-toxin (AT) and clumping factor A (ClfA), especially in combinat

268 on and the role of pore-forming alpha-toxin (AT), a virulence factor that causes host cell lysis and

269 rsistent SHPT developed in 1 TPTX and 2 TPTX+AT patients.

270 al of 52 patients underwent TPTX and 48 TPTX+AT.

271 thyroidectomy with autotransplantation (TPTX+AT) and subtotal parathyroidectomy (SPTX) are the standa

272 = 0.95) whereas PTH rose by time in the TPTX+AT group and was significantly higher at the end of foll

273 [two phenylalanines (FF) in an acidic tract (AT)] motif.

274 omes, encodes a trans-acyltransferase (trans-AT) polyketide synthase (PKS) multienzyme that was hypot

275 al polyketide biosynthesis mediated by trans-AT polyketide synthases that lack integrated acyl transf

276 bacillaene, difficidin, and mupirocin trans-AT polyketide synthases.

277 nment tool for comparative analysis of trans-AT polyketide synthase assembly line architectures.

278 echanism that likely involves atom transfer (AT), whereas, in the absence of ligand, photoinduced act

279 hases that lack integrated acyl transferase (AT) domains.

280 Acoustic trauma (AT, loud sounds) slow AMPAR-EPSC decay times, increasing

281 Damaging levels of sound (acoustic trauma, AT) diminish peripheral synapses, but what is the impact

282 Adenosine terminated 100% of triggered ATs and transiently slowed or suppressed 100% of automat

283 atic degradation, we used aspirin-triggered (AT)-RvD3: 4S,11R,17R-trihydroxydocosa-5Z,7E,9E,13Z,15E,1

284 mal and steatotic liver using Alb-TSC1(-/-) (AT) and Alb-mTOR(-/-) (Am) transgenic mice.

285 , epithelial cells, primarily alveolar type (AT) I cells, die and slough off, resulting in enhanced p

286 nd the ECM to both "healthy" and "unhealthy" AT expansion.

287 ptome analysis comparing mesenteric visceral AT (vAT) of HF and HF/DDE groups revealed a decrease in

288 nd higher order integration centers, whereas AT immunoreactivity was restricted to the central comple

289 riuretic peptide signaling was seen in white AT of HFpEF mice.

290 ing markers (ucp-1, cidea, and eva) in white AT.

291 h serum total- and LDL-cholesterol, and with AT-specific cholesterol metabolism-associated lipids [ar

292 arasite species are uniquely associated with AT during part of their life cycle: Trypanosoma cruzi, t

293 and Basidiomycota OTUs were associated with AT while Microbacteriaceae and Ascomycota were enriched

294 H-NS, like GapR, selectively associates with AT-rich DNA, yet it does not localize preferentially to

295 s prompted studies of drugs interacting with AT-rich DNA, such as the N-phenylbenzamide bis(2-aminoim

296 ted manifestations observed in patients with AT and Artemis deficiency stem from increased type I IFN

297 and peripheral blood cells of patients with AT, Artemis deficiency, and SAVI.

298 ory manifestations observed in patients with AT, Artemis deficiency, and SAVI.

299 esults indicate that systemic treatment with AT-RvD1 diminishes the progression of the disease in sal

300 At the age of 40 years, AT-free survival in patients with 0, 1, 2, and >/=3 risk