ライフサイエンスコーパス: ATP hydrolysis

1 ry to unwind DNA, in a process that requires ATP hydrolysis.

2 Reverse operation generates PMF via ATP hydrolysis.

3 A unwinding without negatively affecting the ATP hydrolysis.

4 aking them unavailable for actin binding and ATP hydrolysis.

5 are likely to be the basis of inhibition of ATP hydrolysis.

6 unt of DNA translocation by Sth1 relative to ATP hydrolysis.

7 leotide-binding domain closure necessary for ATP hydrolysis.

8 through conformational changes brought on by ATP hydrolysis.

9 or ATP through feedback from the products of ATP hydrolysis.

10 s revealed a peristaltic pumping motion upon ATP hydrolysis.

11 n they translocate solutes at the expense of ATP hydrolysis.

12 e and increase the free energy released from ATP hydrolysis.

13 nanodiscs at 37 degrees C while it performs ATP hydrolysis.

14 ing to SERCA uncouples Ca(2+) transport from ATP hydrolysis.

15 ghtly coupled to priming the active site for ATP hydrolysis.

16 e site that positions catalytic residues for ATP hydrolysis.

17 pounds out of the cell using the energy from ATP hydrolysis.

18 promotes uncoupling of Ca(2+) transport from ATP hydrolysis.

19 tein conformational changes that result from ATP hydrolysis.

20 hen remodels these substrates in response to ATP hydrolysis.

21 djacent microtubules, and it does so without ATP hydrolysis.

22 ent with conformational asymmetry induced on ATP hydrolysis.

23 hese mutants are defective in RNA-stimulated ATP hydrolysis.

24 tial for stimulation of omega2.parS-mediated ATP hydrolysis.

25 adient by utilizing the energy released from ATP hydrolysis.

26 transports Ca(2+) and H(+) at the expense of ATP hydrolysis.

27 and promotes its disassembly by stimulating ATP hydrolysis.

28 strate through their central pore powered by ATP hydrolysis.

29 lved in copper binding and those involved in ATP hydrolysis.

30 e dissociation required little or no further ATP hydrolysis.

31 Thus, substrate is released prior to ATP hydrolysis.

32 sengagement, of the catalytic site following ATP hydrolysis.

33 his ring are perfectly designed for inducing ATP hydrolysis.

34 ted by Sec17 and Sec18:ATP without requiring ATP hydrolysis.

35 nction is species-specific and requires RecN ATP hydrolysis.

36 e (5NT), rather than AP, was responsible for ATP hydrolysis.

37 ross cell membranes with energy derived from ATP hydrolysis.

38 r, such that the buckled conformation favors ATP hydrolysis.

39 substrate binding primes the transporter for ATP hydrolysis.

40 ularly at a checkpoint before RFC commits to ATP hydrolysis.

41 ds on a process driven out of equilibrium by ATP hydrolysis.

42 g is strictly coupled to phosphorylation and ATP hydrolysis.

43 model for the 26S functional cycle driven by ATP hydrolysis.

44 that does not catalyze additional rounds of ATP hydrolysis.

45 ctions within the MBD1-3 group and activates ATP hydrolysis.

46 degrade unassembled EMRE using the energy of ATP hydrolysis.

47 mical energy from adenosine 5'-triphosphate (ATP) hydrolysis.

48 is process relies on adenosine triphosphate (ATP) hydrolysis.

49 ors exhibited 1.8- to 2.5-fold lower rate of ATP hydrolysis, 2.5- to 4.5-fold lower DNA packaging vel

50 The main site of ATP hydrolysis, AAA1, is the only site considered by mos

51 Using the energy of ATP hydrolysis, ABC transporters catalyze the trans-memb

52 The reduced ATP hydrolysis activated AMPK activity in IF1 KO hearts,

53 .6 muM and that an Nbp35 mutant deficient in ATP hydrolysis activity also displays an increased KD fo

54 This protein displays ATP hydrolysis activity and is capable of unwinding dupl

55 ruled out the possibility that the observed ATP hydrolysis activity might result from a contaminatin

56 d rac-cryptopleurine with Hsc70 promotes the ATP hydrolysis activity of Hsc70 in the presence of the

57 ex6 recruitment to peroxisomes, inhibits the ATP-hydrolysis activity of Pex1/Pex6.

58 makes them unavailable for actin binding or ATP hydrolysis, although a small fraction of the myosin

59 Hsp90 is a homodimeric protein that requires ATP hydrolysis and a host of accessory proteins termed c

60 suggest that the binding of Lmod2 stimulates ATP hydrolysis and accelerates actin nucleation and poly

61 Pase activity, suggesting uncoupling between ATP hydrolysis and activation of the gate.

62 Indeed, an altered pattern of ATP hydrolysis and altered allosteric signaling between

63 preceding two strongly endothermic steps of ATP hydrolysis and attachment of M.ADP.Pi to actin.

64 vestigate the role of the N and C termini in ATP hydrolysis and auto-inhibition of the yeast flippase

65 BD1/CL1 binding is a crucial requirement for ATP hydrolysis and channel function.

66 ecades of research, the mechanism connecting ATP hydrolysis and chaperone function remains elusive.

67 we propose a model where direct coupling of ATP hydrolysis and conformational flipping rearranges cl

68 The open conformation is induced by ATP hydrolysis and corresponds to the post-hydrolysis tr

69 vestigations have described the mechanism of ATP hydrolysis and defined the architecture of ABC expor

70 (kcat) is limited by slow, near-irreversible ATP hydrolysis and even slower subsequent phosphate rele

71 R3 with a thiol-reactive fluorophore blocked ATP hydrolysis and exhibited no PC stimulation.

72 ve TATA-binding protein (TBP) from DNA using ATP hydrolysis and in so doing exerts global effects on

73 ect of retinoschisin on Na/K-ATPase-mediated ATP hydrolysis and ion transport.

74 eir degradation, supporting a model in which ATP hydrolysis and linked mechanical function in the Hsl

75 al models implicating the P-loop arginine in ATP hydrolysis and mechanochemical coupling.

76 e Arp5-Ies6 module stimulates INO80-mediated ATP hydrolysis and nucleosome sliding in vitro.

77 This binding mode suggests that ATP hydrolysis and phosphate release may proceed by a st

78 In vitro ATP hydrolysis and proton transport were reduced by 35%

79 ed a wild-type-like enzyme turnover rate for ATP hydrolysis and rate of cellular K(+) uptake.

80 r in combination with direct manipulation of ATP hydrolysis and release.

81 ker of eIF4AI regulates the coupling between ATP hydrolysis and RNA unwinding.

82 l PilB mutant variant, which is deficient in ATP hydrolysis and T4P assembly, supports EPS production

83 n why maintaining the OC requires continuous ATP hydrolysis and the function of TFIIH in promoter esc

84 The first mechanism requires ATP hydrolysis and the protein conducting channel cpSecY

85 T cells (from CD39(-/-) mice) did not alter ATP hydrolysis and very likely involves pyrophosphatases

86 ynthesis capabilities but, failed to restore ATP hydrolysis and was insensitive to various inhibitors

87 CD39-induced ATP hydrolysis and/or adenosine generation contribute to

88 he hyperactive state is only reached through ATP hydrolysis, and not ATP binding.

89 Quantitative kinetic measurements of ET, ATP hydrolysis, and Pi release during the presteady-stat

90 s dependent on the p97 adaptor NPLOC4-UFD1L, ATP hydrolysis, and substrate ubiquitination, with branc

91 ound to dsRNA in a manner dependent on their ATP hydrolysis, and that this activity assists a dsRNA-d

92 pose that modest domain motions accompanying ATP hydrolysis are amplified, through changes in electro

93 ants, we find that Spa47 oligomerization and ATP hydrolysis are needed for complete T3SS apparatus fo

94 the presence of ATP, binding, cleavage, and ATP hydrolysis are optimal with BLT termini compared to

95 Here we investigate the regulation of ATP hydrolysis as well as the interdependence of the two

96 of DNA at sites of protein adducts requires ATP hydrolysis at both sites, as does the stimulation of

97 troduction of sensor-1 mutations that reduce ATP hydrolysis at NBD1 (T317A) or NBD2 (N728A).

98 hindrance; Nas6 clashes with the lid in the ATP-hydrolysis-blocked proteasome, but clashes instead w

99 Stochasticity of ATP hydrolysis breaks the initial symmetry in ParA distr

100 hanism of condensin depends on the energy of ATP hydrolysis but how this activity specifically promot

101 e, the alpha-helices are proposed to inhibit ATP hydrolysis by assuming an "up" state, where the alph

102 We find that double-stranded DNA stimulates ATP hydrolysis by hMRN over approximately 20-fold in an

103 These allosteric effects thus reduce ATP hydrolysis by inactive proteasomes and nonspecific p

104 from BiP 6-fold and abolished stimulation of ATP hydrolysis by J-domain cofactor.

105 ssium transport through KdpA is coupled with ATP hydrolysis by KdpB remains poorly understood.

106 ATP hydrolysis by MCM is required for loading and the po

107 try and bound to ATP until ORC-Cdc6 triggers ATP hydrolysis by MCM, promoting both Cdt1 ejection and

108 We also found that Rif2 enhances ATP hydrolysis by MRX and attenuates MRX function in end

109 ATP hydrolysis by Pex1 is highly coordinated with that o

110 The rate of ATP hydrolysis by Pif1 is reduced when bound to a parall

111 pha7 anchors ribose and controls the rate of ATP hydrolysis by retarding the expulsion of ADP.

112 ompletely understood mechanism that involves ATP hydrolysis by RIG-I's RNA translocase domain.

113 ABL) that is critical for the stimulation of ATP hydrolysis by RNA.

114 However, the mechanism through which ATP hydrolysis by SecA is coupled to directional movemen

115 and sarcolipin on calcium translocation and ATP hydrolysis by SERCA under conditions that mimic envi

116 otes, the drive for translocation comes from ATP hydrolysis by the cytosolic motor-protein SecA, in c

117 ATP hydrolysis by the D1 ring is important for subsequen

118 eraction of the polyubiquitin chain with UN, ATP hydrolysis by the D2 ring moves the polypeptide comp

119 We show that ATP hydrolysis by the ESX ATPase is required for secreti

120 haperone Sgt2 and kinetic proofreading after ATP hydrolysis by the targeting factor Get3.

121 The removal of RecA from DNA also requires ATP hydrolysis by the UvrD helicase but not by RecA prot

122 We provide evidence that ATP hydrolysis by UPF1 is required for efficient transla

123 Our results reveal that ATP hydrolysis by UPF1 modulates a functional interactio

124 ATP hydrolysis by WT proteasomes is activated if they bi

125 To elucidate the catalytic mechanism of ATP hydrolysis by YchF, we have taken a two-pronged appr

126 ata, we propose that adenosine triphosphate (ATP) hydrolysis by CglI produces translocation on DNA pr

127 hat insight into its allosteric mechanism of ATP hydrolysis can be achieved by Arrhenius analysis.

128 tes, providing a paradigm of how energy from ATP hydrolysis can be used for client remodeling.

129 DNA-bound RecA protein increases the rate of ATP hydrolysis catalysed by RecN during the DNA pairing

130 ens the pore, and dimer disruption following ATP hydrolysis closes it.

131 some, but clashes instead with the CP in the ATP-hydrolysis-competent proteasome.

132 To achieve this, p97 requires ATP hydrolysis, cooperates with the Ufd1-Npl4 ubiquitin-

133 ding member of DEAD-box helicases, undergoes ATP hydrolysis-coupled conformational changes to unwind

134 nce of Tpm1.12 extends the time required per ATP hydrolysis cycle 3.7-fold, whereas it is shortened b

135 formational changes in human P-gp during the ATP hydrolysis cycle has not been directly demonstrated,

136 PRNT reveals two mechanical substates of the ATP hydrolysis cycle of the superfamily 2 helicase Hel30

137 rge conformational rearrangements during its ATP hydrolysis cycle that differ dramatically from the c

138 nalogs that can mimic multiple states in the ATP hydrolysis cycle.

139 The ATP hydrolysis cycles of its two heads are maintained ou

140 Accordingly, the ATP hydrolysis-defective dna2-K1080E mutant is less able

141 he membrane via a soluble intermediate in an ATP hydrolysis-dependent manner.

142 Here we demonstrate an additional ATP-hydrolysis-dependent association of MukBEF with the

143 ynamics simulations provide insight into how ATP hydrolysis destabilizes strand exchange products.

144 ATP hydrolysis displaces wild-type RIG-I from this self-

145 However, we show that ATP hydrolysis does provide an important function by rec

146 Our findings suggest that the ATP hydrolysis-driven conformational changes in both DNA

147 ) oligomerize through AAA(+) domains and use ATP hydrolysis-driven energy to isomerize the RNA polyme

148 nation and deprotonation of the c-ring, with ATP-hydrolysis-driven rotation causing protonation of a

149 rs on single- or double-stranded DNA and how ATP hydrolysis drives DNA unwinding remain open question

150 ATP hydrolysis drives rotation of the nucleotide-binding

151 diet had greater free energy available from ATP hydrolysis during increased work than did hearts fro

152 At room temperature, blocking ATP hydrolysis effectively abolished slow endocytosis an

153 otor on the prohead's portal vertex and uses ATP hydrolysis energy for DNA translocation.

154 r experiments reveal that in the presence of ATP hydrolysis even 75 bp sequence-matched strand exchan

155 new compound series inhibits TarH-catalyzed ATP hydrolysis even though the binding site maps to TarG

156 n quadruplex unfolding, indicating that some ATP hydrolysis events are non-productive during unfoldin

157 Repetitive cycles of sequential intra-ring ATP hydrolysis events induce axial excursions of diaphra

158 However, how ATP hydrolysis facilitates removal of TBP from DNA is no

159 and recruits BiP through the stimulation of ATP hydrolysis, forcibly disrupting IRE1 dimers.

160 upported by the observed increase in kcat of ATP hydrolysis, from 7.8 +/- 0.1 min-1 to 457.7 +/- 9.2

161 Biochemical analysis reveals that ATP hydrolysis-fueled translocation of Dna2 on ssDNA fac

162 involved in a functional cycle accompanying ATP hydrolysis has been investigated in unprecedented de

163 iscovered that the chemical free energy from ATP hydrolysis has to be strategically assigned to the M

164 ans-arginine finger, R158, indispensable for ATP hydrolysis; (iii) the location of this arginine is c

165 y the arginine finger residue that catalyzes ATP hydrolysis in a neighboring motor subunit, illustrat

166 The roles of ATP hydrolysis in electron-transfer (ET) reactions of th

167 A binding to the ARL allosterically triggers ATP hydrolysis in PriA.

168 lacking unique insertion domains facilitates ATP hydrolysis in the absence of nucleosome sliding.

169 activase, it merely enhances the kinetics of ATP hydrolysis in the algal enzyme.

170 nature of the conversion of chemical energy (ATP hydrolysis in the alpha/beta-subunits) to mechanical

171 er nucleotide release than ATP suggests that ATP hydrolysis in the bound head precedes stepping by th

172 estigate this type of force originating from ATP hydrolysis in the chaperonin GroEL, by applying forc

173 At its heart are two main ideas: i) ATP hydrolysis in the CI domain provides the thermodynam

174 of the exporter class harness the energy of ATP hydrolysis in the nucleotide-binding domains (NBDs)

175 d chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding m

176 Subsequent UvrB recruitment requires ATP hydrolysis in the proximal site.

177 ATP hydrolysis in the soluble catalytic V1 region drives

178 ficient HELLS variant to address the role of ATP hydrolysis in this process.

179 The essential mechanistic role of Cdc6 ATP hydrolysis in this reaction is still incompletely un

180 key to the coupling of maltose transport to ATP hydrolysis in vivo, because it facilitates the progr

181 eady state, the ratio of proton transport to ATP hydrolysis increased 24% after increasing the glucos

182 uctural mechanism to convert the energy from ATP hydrolysis into a large swing of the force-generatin

183 ht on how superfamily 1 and 2 helicases turn ATP hydrolysis into motion along DNA.

184 Furthermore, once ATP hydrolysis is abolished, the R117H mutant can be tra

185 Here we report that prolonged ATP hydrolysis is beneficial to the ABC transporter BtuC

186 Displacement of MukBEF is impaired when MukB ATP hydrolysis is compromised and when MatP is absent, l

187 , to understand the molecular details of how ATP hydrolysis is coupled to calcium transport, it is ne

188 The structure suggests how ATP hydrolysis is coupled to long-range diffusion of a h

189 will be a useful tool for understanding how ATP hydrolysis is coupled to LPS transport.

190 ATP hydrolysis is critically important for remodeling th

191 ts nucleolytic processing of DNA ends, while ATP hydrolysis is essential for Mre11 endonuclease activ

192 Here, we show that although Cdc6 ATP hydrolysis is essential to initiate DNA replication,

193 reveal that the chemical energy produced by ATP hydrolysis is harnessed via the concerted motion of

194 lysis of the helicase activity revealed that ATP hydrolysis is not required because both adenosine 5'

195 Additionally, we reveal that actin ATP hydrolysis is not required for VASP-mediated filamen

196 Experiments also indicate that when ATP hydrolysis is present, flanking heterologous dsDNA r

197 ATP hydrolysis is related to detachment of EHD2 from the

198 Interconversion between these two forms by ATP hydrolysis is required for release of Rrp5 from pre-

199 ATP hydrolysis is required for the long-distance communi

200 Cdc6 ATP hydrolysis is therefore required for Cdc6 disengagem

201 upling ratio and an activated state in which ATP hydrolysis is tightly coupled to proton transport.

202 S that is still conductive, but defective in ATP hydrolysis, is not phosphorylated, suggesting that p

203 However, the rate constant for ATP hydrolysis (k+H + k-H) was reduced by approximately

204 utward-facing, closed NBD conformation), and ATP hydrolysis leads to dissociation of the NBDs with th

205 r structure answers the key questions of how ATP hydrolysis leads to linker remodelling and microtubu

206 Subsequent ATP hydrolysis leads to substrate delivery to the cytopl

207 e capture by the transporter, and subsequent ATP hydrolysis led to substrate release.

208 Kinesin-8/Kip3 uses ATP hydrolysis, like other kinesins, for stepping on the

209 rder of their response times; (3) the matrix ATP hydrolysis mass action ratio [ADP] x [Pi]/[ATP] prov

210 e prevalence of helicases in RNA regulation, ATP hydrolysis may be a widely used activity in target R

211 el an activated Spa47 oligomer, finding that ATP hydrolysis may be supported by specific side chain c

212 -induced ring closure templates a sequential ATP-hydrolysis mechanism, provide a molecular rationale

213 After stimulation of ATP hydrolysis, MinE remains bound to the membrane in a

214 mic assembly of filamentous actin, involving ATP hydrolysis, N-WASP and formin, mediates Omega-profil

215 In contrast, under conditions of ATP hydrolysis, Nas6 obstructs base-CP, but not base-lid

216 upling," and Post-HSA mutations that improve ATP hydrolysis; notably, the strongest mutations conferr

217 ATP hydrolysis occurs at a faster rate than quadruplex u

218 A remodeling activity can tolerate defective ATP hydrolysis of alternating subunits.

219 p97 N-D1 truncate has been shown to activate ATP hydrolysis of its D1-domain, although the mechanism

220 ith IC50 = 0.75 muM and stimulated the basal ATP hydrolysis of P-gp in a concentration-dependent mann

221 acting arginine-finger residue essential for ATP hydrolysis of the D1-domain.

222 was similar to the Hsp40-stimulated rate of ATP hydrolysis of wild-type Ssa1.

223 ather than being cooperative or independent, ATP hydrolysis on the two protomers is sequential and de

224 ons in the DEAD-box ATPase Dhh1 that prevent ATP hydrolysis, or that affect the interaction between D

225 lytic cycle, and demonstrate that, following ATP hydrolysis, P-gp transitions through a complete clos

226 sulted in a complex with trapped products of ATP hydrolysis: phosphate ion and ADP.

227 imal cells is vital for actively maintaining ATP hydrolysis-powered Na(+) and K(+) electrochemical gr

228 Reactivation requires ATP-hydrolysis-powered remodeling of the inhibited compl

229 Our results indicate that ATP-hydrolysis prevents recognition of self-RNA and sugg

230 r of the motor, uncoupled the release of the ATP hydrolysis product, inorganic phosphate (Pi), from d

231 /closure/release, ptDNA binding/release, and ATP hydrolysis/product release.

232 d activation of NM-2B and the release of the ATP hydrolysis products ADP and phosphate from the activ

233 ADH synthesis and respiration, feedback from ATP hydrolysis products, and stimulation by calcium were

234 tribution (>/=90%) to the total CFTR-related ATP hydrolysis rate is due to phosphorylation by PKA and

235 closed states did not affect stimulation of ATP hydrolysis rates in the absence of membrane binding,

236 embrane-targeting sequence stimulated higher ATP hydrolysis rates than the full-length protein, indic

237 ed with the repeats have altered kinetics of ATP hydrolysis relative to complexes with bona fide MMR

238 MoFe protein and includes electron transfer, ATP hydrolysis, release of Pi, and dissociation of the o

239 -associated I-2 binds to DNA, which enhances ATP hydrolysis, releasing ADP-bound I-2 from the DNA.

240 o allosterically impair J protein-stimulated ATP-hydrolysis, resulting in the inability of modified B

241 Although the data simplifies the ATP hydrolysis scheme for Type III restriction enzymes,

242 e DNA-binding channel, forming an additional ATP hydrolysis site.

243 es, most notably the slowing of the apparent ATP hydrolysis step (reduced 5-9-fold), leading to a lon

244 mic localization is driven by MinD-catalyzed ATP hydrolysis, stimulated by interactions with MinE's a

245 ion is achieved through expending energy via ATP hydrolysis, suggesting that it is coupled to TFIIH's

246 Tests for ATP hydrolysis / synthesis, oxygen consumption, glycolyt

247 s still unknown how the substrate stimulates ATP hydrolysis, the hallmark of ABC transporters.

248 With the use of the energy of ATP hydrolysis, the Na+/K+-ATPase is able to transport a

249 nce of verapamil, a substrate that activates ATP hydrolysis, the NBDs of Pgp reconstituted in nanodis

250 P-gp uses ATP hydrolysis to catalyze the transport of a broad rang

251 protein, alphaSNAP, and using the energy of ATP hydrolysis to disassemble the complex.

252 c AAA+ protein found in yeast, which couples ATP hydrolysis to disassembly and reactivation of protei

253 tin remodeling complex, uses the energy from ATP hydrolysis to disrupt nucleosomes at target regions.

254 ternary complex with TBP and DNA and can use ATP hydrolysis to dissociate the TBP-DNA complex.

255 However, how this motor couples ATP hydrolysis to DNA translocation is still unknown.

256 bstrates in a unified mechanism that couples ATP hydrolysis to DNA unwinding is unknown.

257 Fe) protein, where light harvesting replaces ATP hydrolysis to drive the enzymatic reduction of N2 in

258 re undergoes in a concerted action to couple ATP hydrolysis to ESCRT-III substrate disassembly.

259 multidrug transporter that uses energy from ATP hydrolysis to export many structurally dissimilar hy

260 n proposed to explain how Cdc48 might couple ATP hydrolysis to forcible unfolding, dissociation, or r

261 rse set of proteins that use the energy from ATP hydrolysis to form dynamic, linear polymers.

262 t mediate p31(comet)-Mad2 binding and couple ATP hydrolysis to local unfolding of Mad2.

263 ex mediates export; however, the coupling of ATP hydrolysis to movements of the precursor through the

264 Helicases couple ATP hydrolysis to nucleic acid binding and unwinding via

265 ndividually and synergistically that couples ATP hydrolysis to nucleosome sliding.

266 how cohesin regulators harness the energy of ATP hydrolysis to open the cohesin ring and enable dynam

267 DNA-sensing lysines trigger ATP hydrolysis to open the SMC head interface, whereas t

268 ular motor that harnesses the free energy of ATP hydrolysis to perform mechanical work on DNA.

269 p5-Ies6 assembly, which are needed to couple ATP hydrolysis to productive nucleosome movement.

270 moving force (pmf), or uses the energy from ATP hydrolysis to pump protons against the concentration

271 remodeling complexes utilize the energy from ATP hydrolysis to reorganize chromatin and, hence, regul

272 and ADP-bound states explain the coupling of ATP hydrolysis to RNA translocation, mainly mediated by

273 e the torque generated by F1, switching from ATP hydrolysis to synthesis at a very low value of 'stal

274 n structure by coupling the free energy from ATP hydrolysis to the repositioning and restructuring of

275 ity control system, coupling the energy from ATP hydrolysis to threading substrate proteins (SP) thro

276 binding cassette exporters use the energy of ATP hydrolysis to transport substrates across membranes

277 de later, other chaperones were shown to use ATP hydrolysis to unfold and solubilize stable protein a

278 the family of DExH-box helicases, which use ATP hydrolysis to unwind RNA secondary structures.

279 nesin and dynein use the energy derived from ATP hydrolysis to walk processively along microtubule tr

280 at use the energy of adenosine triphosphate (ATP) hydrolysis to remodel nucleosomes.

281 he equilibrium constant for myosin-catalyzed ATP hydrolysis toward the posthydrolysis biochemical sta

282 n of Hsp104 hexamers in ATPgammaS, ADP-AlFx (ATP hydrolysis transition-state mimic), and ADP via smal

283 uman cytoplasmic dynein-2 motor bound to the ATP-hydrolysis transition state analogue ADP.vanadate.

284 Our results show that ATP hydrolysis triggers sequential conformational waves.

285 the number of myosin motors leaving the off, ATP hydrolysis-unavailable state characteristic of the d

286 serving as an accelerator that enables rapid ATP hydrolysis upon contact with ptDNA and RFC-D Arg-101

287 transinhibition, we studied the kinetics of ATP hydrolysis using detergent-solubilized MetNI.

288 itioned loops may also couple DNA binding to ATP hydrolysis using related mechanisms.

289 Without ADP, the Hill coefficient for ATP hydrolysis was extracted to be 1.0 +/- 0.1, indicati

290 ATP hydrolysis was required for dissociation of the micr

291 g revealed a peristaltic pumping motion upon ATP hydrolysis, which drives directional substrate trans

292 onfiguration of the linker domain induced by ATP hydrolysis, which occur some 25 nm apart.

293 Analysis of ATP hydrolysis with and without conformational restraint

294 onserved motor domain that couples cycles of ATP hydrolysis with conformational changes to produce mo

295 the ARL was similar to loops known to couple ATP hydrolysis with DNA binding in a subset of other SF2

296 400E mutation did not affect the coupling of ATP hydrolysis with electron transfer (ET) between FeP a

297 ncation did not change the intrinsic rate of ATP hydrolysis with membranes.

298 Of note, our model connected the site for ATP hydrolysis with sites that ultimately utilize its fr

299 amily of ATP-driven proton pumps that couple ATP hydrolysis with translocation of protons across memb

300 activated" state overcomes its impediment in ATP hydrolysis, with the subsequent release of both of t