ライフサイエンスコーパス: ATP-dependent protease

1 of substrate release from ClpXP, a bacterial ATP-dependent protease.

2 d that FtsZ is degraded by E. coli ClpXP, an ATP-dependent protease.

3 ifferent form after its first turnover as an ATP-dependent protease.

4 tity to the Escherichia coli Lon protein, an ATP-dependent protease.

5 ein degradation is a common feature found in ATP-dependent proteases.

6 emoved in an efficient and timely fashion by ATP-dependent proteases.

7 y Lon or any of the cell's known cytoplasmic ATP-dependent proteases.

8 ss some membranes and protein degradation by ATP-dependent proteases.

9 o protect normal proteins, is carried out by ATP-dependent proteases.

10 yotes for marking proteins to be degraded by ATP-dependent proteases.

11 Lon1 is an ATP-dependent protease and chaperone located in the mito

12 t human ClpX and ClpP constitute a bone fide ATP-dependent protease and confirm that substrate select

13 rain CB1541 there were mutations in clpP, an ATP-dependent protease, and two different hypothetical p

14 Lon ATP-dependent proteases are key components of the protei

15 Integral components of ATP-dependent proteases are motor proteins that unfold s

16 ATP-dependent proteases are processive, meaning that the

17 Self-compartmentalized ATP-dependent proteases are required for virulence of se

18 ATP-dependent proteases are responsible for most energy-

19 ATP-dependent proteases are vital to maintain cellular p

20 As multicomponent ATP-dependent proteases are widespread in nature and sha

21 to gain insight into the mechanism by which ATP-dependent proteases attain processivity in protein d

22 -oligomer and represents one of the simplest ATP-dependent proteases because both the protease and AT

23 We propose that substrates of ATP-dependent proteases bind to specific sites on the di

24 e copies of genes encoding the ClpP and FtsH ATP-dependent proteases but lacks the Lon and HslV prote

25 In the case of the bacterial ATP-dependent protease ClpAP, ATP hydrolysis by the ClpA

26 ptor protein ClpS, an essential regulator of ATP-dependent protease ClpAP, directly interacted with P

27 The Escherichia coli ATP-dependent protease, ClpAP, is composed of the hexame

28 ity and proteolytic activity for the E. coli ATP-dependent protease, ClpAP, is modulated by an adapto

29 id not inhibit the activity of other E. coli ATP-dependent proteases, ClpAP or ClpYQ.

30 ontrolled at the level of proteolysis by the ATP-dependent protease ClpXP and a substrate-binding pro

31 ytic control exerted by the adaptor YjbH and ATP-dependent protease ClpXP in Bacillus subtilis.

32 centrations during unperturbed growth by the ATP-dependent protease ClpXP.

33 lis, is under the proteolytic control of the ATP-dependent protease ClpXP.

34 es the proteolytic elimination of Spx by the ATP-dependent protease ClpXP.

35 d by proteolysis, mediated by the ubiquitous ATP-dependent protease ClpXP.

36 concentration increases in cells lacking the ATP-dependent protease, ClpXP, resulting in severe effec

37 , but is instead rapidly degraded by another ATP-dependent protease, ClpXP.

38 l et al. (2015) report that proteasomes, the ATP-dependent protease complexes that execute ubiquitin-

39 including the major chaperone proteins, five ATP-dependent protease complexes, and several cold and h

40 HslVU is a new Escherichia coli ATP-dependent protease composed of two multimeric comple

41 ATP-dependent proteases control the concentrations of hu

42 ATP-dependent proteases degrade denatured or misfolded p

43 Among other functions, ATP-dependent proteases degrade misfolded proteins and r

44 ATP-dependent proteases degrade proteins in the cytosol

45 leavage step is rate-limiting; that multiple ATP-dependent proteases degrade the cytoplasmic fragment

46 ClpXP, an ATP-dependent protease, degrades hundreds of different i

47 ATP-dependent proteases engage, translocate, and unfold

48 We have isolated a new type of ATP-dependent protease from Escherichia coli.

49 is the only membrane-anchored and essential ATP-dependent protease in Escherichia coli.

50 erved in prokaryotes, and the only essential ATP-dependent protease in Escherichia coli.

51 The proteasome is the major ATP-dependent protease in eukaryotic cells, but limited

52 that demonstrates a direct role for the Lon ATP-dependent protease in the degradation of tmRNA-tagge

53 verlapping that of the Lon protease, another ATP-dependent protease in which a single subunit contain

54 There are five known ATP-dependent proteases in Escherichia coli (Lon, ClpAP,

55 e removal of damaged or unneeded proteins by ATP-dependent proteases is crucial for cell survival in

56 Lon protease but no other known ATP-dependent proteases is required for persistence.

57 e show that PhoADelta2-22 is degraded by two ATP-dependent proteases, La (Lon) and ClpAP, and breakdo

58 Yme1p, an ATP-dependent protease localized in the mitochondrial in

59 The ATP-dependent protease Lon (La) of Escherichia coli degr

60 ium smegmatis gene encoding a homolog of the ATP-dependent protease Lon (La).

61 The ATP-dependent protease Lon was also found to negatively

62 itoxins are proteolytically regulated by the ATP-dependent proteases Lon and ClpP.

63 We found that Xis is degraded in vivo by two ATP-dependent proteases, Lon and FtsH (HflB).

64 In this study, the ATP-dependent proteases LonA and B and the regulatory AT

65 ATP-dependent proteases maintain protein quality control

66 The ClpYQ (HslUV) ATP-dependent protease of Escherichia coli consists of a

67 Compartmented ATP-dependent proteases of diverse origin share conserve

68 The 26S proteasome is a multi-subunit ATP-dependent protease responsible for degrading most sh

69 Lon protein of Escherichia coli is an ATP-dependent protease responsible for the rapid turnove

70 ls of lysosomal proteolysis or the action of ATP-dependent proteases such as bacterial lon.

71 ting the activity of mitochondrial LONP1, an ATP-dependent protease that controls the selective turno

72 Lon is an ATP-dependent protease that degrades unstructured protei

73 ClpXP is an ATP-dependent protease that denatures native proteins an

74 ClpP is the proteolytic component of an ATP-dependent protease that is essential for the proper

75 The 26S proteasome is a 2.5-MDa, 32-subunit ATP-dependent protease that is responsible for the degra

76 Proteasomes are essential and ubiquitous ATP-dependent proteases that function in eukarya, archae

77 hat mycobacterial species contain additional ATP-dependent proteases that have broad substrate specif

78 Among the ATP-dependent proteases, those of the Clp family are par

79 ities of representatives from all classes of ATP-dependent proteases to unfold a model substrate prot

80 ATP-dependent proteases translocate and unfold their sub

81 ATP-dependent proteases translocate proteins through a n

82 AAA family of proteins, is the only membrane ATP-dependent protease universally conserved in prokaryo

83 Other well-studied ATP-dependent proteases use ATP to unfold their substrat

84 also known as protease La, is an oligomeric ATP-dependent protease, which functions to degrade damag