ライフサイエンスコーパス: Acanthamoeba

1 otential of the facultative amoebal parasite Acanthamoeba.

2 bor dormant-resistant stages of Fusarium and Acanthamoeba.

3 tive against bacteria than fungal species or Acanthamoeba.

4 d by several free-living amebae of the genus Acanthamoeba.

5 ydrostigmasterol or any other phytosterol in Acanthamoeba.

6 , cloned, and characterized a novel MBP from Acanthamoeba.

7 mology 3 (SH3) domain of type I myosins from Acanthamoeba.

8 oscopy are helpful for diagnosing fungus and Acanthamoeba.

9 definite fungus; kappa was 0.72 for definite Acanthamoeba.

10 lpha-demethylase as the target for azoles in Acanthamoeba.

11 the eye is uninflamed and medically cured of Acanthamoeba.

12 ts suggest that promoter elements within the Acanthamoeba 5S RNA gene are somewhat redundant, with th

13 The promoter region of the Acanthamoeba 5S rRNA gene was analysed by in vitro trans

14 s hypothesized to have had insufficient anti-Acanthamoeba activity.

15 person with dual Balamuthia mandrillaris and Acanthamoeba amebic encephalitis with neurotoxoplasmosis

16 IV infection and Balamuthia mandrillaris and Acanthamoeba amebic encephalitis with Toxoplasma gondii

17 profiles documented the efficient uptake of Acanthamoeba amino acids into the LCV and further into L

18 Acanthamoeba amoeba in 16 solutions (80 %) collected fro

19 Nine ATCC strains of Acanthamoeba and 40 delinked, biobanked, surplus corneal

20 The largest known DNA viruses infect Acanthamoeba and belong to two markedly different famili

21 genes) determined the genotypic diversity of Acanthamoeba and found that many named species of Acanth

22 There have been epidemic increases in Acanthamoeba and fungal keratitis associated with partic

23 ich might both promote the immune evasion of Acanthamoeba and limit the induced inflammatory response

24 Truncated myosins from Acanthamoeba and other model organisms have been visuali

25 cluding Megavirus, Mimivirus (both infecting acanthamoeba), and a virus infecting the marine microfla

26 lso showed that cofilins from fission yeast, Acanthamoeba, and human sever actin filaments optimally

27 luding strains of Legionella, Mycobacterium, Acanthamoeba, and Pseudomonas, are now frequently cited

28 t been observed in environmental isolates of Acanthamoeba, and their natural ecological niche is unkn

29 hamoeba and found that many named species of Acanthamoeba are associated with particular genotypes.

30 Pathogenic isolates of Acanthamoeba are medically relevant as the causative age

31 Both Fusarium and Acanthamoeba at concentrations tested above 10(3) per mL

32 completely killing 15 different isolates of Acanthamoeba at time points of 24, 48, and 72 hours in c

33 More than 20 species of Acanthamoeba belonging to morphological groups I, II, an

34 e sequencing of the mimivirus, a parasite of Acanthamoeba, blurs the boundary between viruses and cel

35 ve a specific organism present (10 fungus, 1 Acanthamoeba) but had negative results via culture and l

36 our results indicating that intoxication of Acanthamoeba by these exotoxins does not require a recep

37 red strains of genomic model taxa including: Acanthamoeba, Cafeteria, Cercomonas, Chlamydomonas, Chlo

38 Free-living amoebae of the genus Acanthamoeba can cause severe and chronic infections in

39 rse soil amoebas including Dictyostelium and Acanthamoeba can host intracellular bacteria.

40 RMIL homology 3 (CAH3) domain from mouse and Acanthamoeba CARMIL rapidly and potently restores actin

41 Acanthamoeba CARMIL was previously shown to co-purify wi

42 is and when assessing the persistent rise in Acanthamoeba cases in the United States since 2003.

43 Infection of EpiCorneal cells with Acanthamoeba castellanii 50493 and A. polyphaga 50372 le

44 decreased by nearly 3 orders of magnitude in Acanthamoeba castellanii amoebae and nearly 2 orders of

45 atest overall inhibition for all isolates of Acanthamoeba castellanii and Acanthamoeba polyphaga test

46 against two potentially pathogenic species, Acanthamoeba castellanii and Acanthamoeba polyphaga, and

47 umophila promotes intracellular infection of Acanthamoeba castellanii and Hartmannella vermiformis, t

48 cells, including macrophages and the amoebae Acanthamoeba castellanii and Hartmannella vermiformis.

49 Following encystment in Acanthamoeba castellanii and reversion of cysts to amoeb

50 Pathogenic mycobacteria lyse Acanthamoeba castellanii in an Esx-1-dependent manner.

51 coded Stx efficiently kills the bacteriovore Acanthamoeba castellanii in co-culture.

52 stinct hosts, the mutants were evaluated for Acanthamoeba castellanii invasion.

53 Acanthamoeba castellanii is a ubiquitous free-living amo

54 MS), we demonstrate that the major sterol of Acanthamoeba castellanii is ergosterol and identify nove

55 f the TATA box binding protein (TBP) gene in Acanthamoeba castellanii is regulated by TATA box bindin

56 Here we report that the eukaryote Acanthamoeba castellanii lacks the G(-1) identity elemen

57 Acanthamoeba castellanii mannose-binding protein (MBP) m

58 We describe a quantitative analysis of Acanthamoeba castellanii myosin II rod domain images col

59 catalytic motor domain of the heavy chain of Acanthamoeba castellanii myosin-2 and the phosphomimetic

60 eplicated less efficiently in phytate-loaded Acanthamoeba castellanii or Dictyostelium discoideum, an

61 in this group, which is capable of infecting Acanthamoeba castellanii Pacmanvirus A23 has a linear co

62 closest homolog in Pandoraviruses and 10% in Acanthamoeba castellanii probably through horizontal gen

63 examined possible mechanisms to explain why Acanthamoeba castellanii remains restricted to the corne

64 f amino acids from the natural host organism Acanthamoeba castellanii to Legionella pneumophila under

65 ft] were tested for their efficacies against Acanthamoeba castellanii trophozoites and cysts by using

66 When Acanthamoeba castellanii trophozoites are grown in methy

67 Acanthamoeba castellanii trophozoites were grown in pept

68 Acanthamoeba castellanii were exposed to varying strengt

69 -2006 keratitis outbreak and trophozoites of Acanthamoeba castellanii were inoculated into commercial

70 Infection in murine macrophages, amoebae (Acanthamoeba castellanii), nematodes (Caenorhabditis ele

71 Among these, Acanthamoeba castellanii, A. polyphaga, and A. hatchetti

72 tected by certain individual assays included Acanthamoeba castellanii, Acanthamoeba culbertsoni, and

73 at five FLA species (Acanthamoeba polyphaga, Acanthamoeba castellanii, Acanthamoeba lenticulata, Verm

74 ir L. pneumophila growth in the amoebal host Acanthamoeba castellanii, demonstrating a host-specific

75 n intracellular multiplication in the amoeba Acanthamoeba castellanii, indicating that certain dotA/B

76 The animals were then infected via Acanthamoeba castellanii-laden contact lenses.

77 intracellular growth in the unicellular host Acanthamoeba castellanii.

78 nea and Cbu.L1951 from lower eukaryotes like Acanthamoeba castellanii.

79 ic cell line U937 and the environmental host Acanthamoeba castellanii.

80 hamsters resistant to corneal infection with Acanthamoeba castellanii.

81 red for full virulence in the protozoan host Acanthamoeba castellanii.

82 viously for this fungus with macrophages and Acanthamoeba castellanii.

83 t phenotype (REP) in the free-living amoeba, Acanthamoeba castellanii.

84 eement with in vivo competition assays using Acanthamoeba castellannii or human macrophage-like U937

85 The soil amoebae Acanthamoeba causes Acanthamoeba keratitis, a severe sig

86 to the putative membrane-binding domains of Acanthamoeba class I myosins.

87 inite fungus (kappa: 0.88-0.95) and definite Acanthamoeba classification (kappa: 0.63-0.90).

88 Here, we asked whether Acanthamoeba clinical isolates from non-AK infections ar

89 Infection is usually initiated by Acanthamoeba-contaminated contact lenses and produces ex

90 einases are responsible for the induction of Acanthamoeba CPE, led us to propose that human mucosal s

91 Acanthamoeba culbertsoni is an opportunistic pathogen th

92 al assays included Acanthamoeba castellanii, Acanthamoeba culbertsoni, and Acanthamoeba lenticulata.

93 Four clinical samples were Acanthamoeba culture negative and real-time PCR positive

94 aPA activity of Acanthamoeba cultures was quantitated by radial diffusio

95 volume of drug was inoculated with 0.1 mL of Acanthamoeba cysts (range, 1-3 x 10(6)/mL) (determined w

96 the presence or absence of fungal hyphae or Acanthamoeba cysts by the confocal microscopist who perf

97 etermining the depth of fungal filaments and acanthamoeba cysts in infectious keratitis.

98 ucibility for detecting fungal filaments and Acanthamoeba cysts in moderate to large corneal ulcers i

99 We describe here the ability of Acanthamoeba cysts to survive desiccation for more than

100 ns device was constructed and used to expose Acanthamoeba cysts to various levels of UV irradiation.

101 an average log reduction of over 3.5 log of Acanthamoeba cysts when the lens and solution inside of

102 as able to provide a marked log reduction to Acanthamoeba cysts, one of the most resistant ocular dis

103 extraction protocol enabled us to detect 0.7 Acanthamoeba cysts/10 microl and 2.3 Acanthamoeba tropho

104 monstrating that the pathogenic potential of Acanthamoeba directly correlates with the expression lev

105 eveloped for the detection of genus-specific Acanthamoeba DNA but lacked clinical validation.

106 Acanthamoeba DNA is nucleosomal with a repeat of approxi

107 s no standard in vitro test to evaluate anti-Acanthamoeba drugs.

108 We investigated the potential effect of Acanthamoeba-endosymbiont coinfection in a human corneal

109 of trophozoites of five different species of Acanthamoeba exhibiting various degrees of pathogenic po

110 r genotypic identification of 29 isolates of Acanthamoeba from non-AK infections.

111 d with trophozoites of a clinical isolate of Acanthamoeba (genotype T4) or stimulated with amoeba-der

112 T2, T4, and T5 genotypes of Acanthamoeba have been identified, and T4 isolates were

113 equences are both suitable for genotyping of ACANTHAMOEBA: However, the mitochondrial sequences are s

114 ngal infection was detected in 176 (74%) and Acanthamoeba in 17 (7%) by microbiological methods.

115 part of an anti-predator strategy; it kills Acanthamoeba in co-culture.

116 the potential to provide protection against Acanthamoeba-induced CPE by an additional mechanism that

117 IgA-depleted milk inhibited the Acanthamoeba-induced CPE in a concentration-dependent ma

118 The antibody also inhibited the Acanthamoeba-induced CPE on host cells.

119 potential to provide protection against the Acanthamoeba-induced cytopathic effect (CPE) by an addit

120 4-, and TLR2/4-deficient mice indicated that Acanthamoeba-induced proinflammatory cytokine production

121 Accordingly, IL-17A neutralization in Acanthamoeba-infected wild-type mice or Acanthamoeba inf

122 as to gain insight into the pathogenicity of Acanthamoeba infection as well as to determine whether o

123 MBP plays a key role in the pathogenesis of Acanthamoeba infection by mediating host-parasite intera

124 mal injection-induced AK model, we show that Acanthamoeba infection induces a strong CD4(+) T effecto

125 We also demonstrate that corneal Acanthamoeba infection induces IL-17A expression and tha

126 n in Acanthamoeba-infected wild-type mice or Acanthamoeba infection of mice lacking IL-17A resulted i

127 article suggest that IL-17A production after Acanthamoeba infection plays an important role in host p

128 Dissecting the immunology of Acanthamoeba infections has been considered problematic

129 enotype T4 is the primary genotype in non-AK Acanthamoeba infections, as was the case in AK infection

130 es/macrophages are thought to be involved in Acanthamoeba infections, but little is known about how t

131 cknowledged as playing a significant role in Acanthamoeba infections, little is known about how this

132 elopment of the inflammatory response during Acanthamoeba infections.

133 We have shown that Acanthamoeba interacts with a mannosylated protein on co

134 k was intended to test the classification of Acanthamoeba into genotypes based on nuclear ribosomal R

135 Acanthamoeba is a free-living ameba that is found throug

136 Acanthamoeba is a free-living protozoan genus found in a

137 The mannose-binding protein (MBP) of Acanthamoeba is thought to play a key role in the pathog

138 Each Acanthamoeba isolate was used to infect EpiCorneal cells

139 Environmental and corneal Acanthamoeba isolates from the American Type Culture Col

140 08.9 +/- 812.5 cells/mm(2); P < 0.0001), and Acanthamoeba keratitis (1000.2 +/- 1090.3 cells/mm(2); P

141 Quantify and describe Acanthamoeba keratitis (AK) cases in British Columbia (B

142 The incidence of acanthamoeba keratitis (AK) in the UK is some 15 times t

143 Acanthamoeba keratitis (AK) is a rare but sight-threaten

144 Acanthamoeba keratitis (AK) is a very painful and vision

145 Nearly all Acanthamoeba keratitis (AK) isolates are genotype RnsT4.

146 l microscopy diagnostic criteria to diagnose Acanthamoeba keratitis (AK) using polymerase chain react

147 lls, a key first step in the pathogenesis of Acanthamoeba keratitis (AK), a devastating corneal infec

148 as the causative agent of sight- threatening Acanthamoeba keratitis (AK), serious infections of other

149 tchetti are frequently identified as causing Acanthamoeba keratitis (AK).

150 ision-threatening corneal infection known as Acanthamoeba keratitis (AK).

151 Oral immunization with MIP133 mitigates Acanthamoeba keratitis and demonstrates the feasibility

152 pecifically, there has been an insurgence of Acanthamoeba keratitis and Fusarium keratitis.

153 entially with herpes simplex keratitis, then Acanthamoeba keratitis before referral.

154 The pathogenesis of Acanthamoeba keratitis begins when Acanthamoeba trophozo

155 (aPA) play key roles in the pathogenesis of Acanthamoeba keratitis by inducing a cytopathic effect o

156 Confirmation of Acanthamoeba keratitis by laboratory diagnosis is the fi

157 n findings can be useful for differentiating acanthamoeba keratitis from bacterial and fungal keratit

158 immune apparatus are important in preventing Acanthamoeba keratitis from progressing to become an int

159 The pathogenesis of Acanthamoeba keratitis is a complex, sequential process.

160 Acanthamoeba keratitis is a debilitating eye disease tha

161 Acanthamoeba keratitis is a serious vision-threatening d

162 Acanthamoeba keratitis is a sight-threatening infection

163 Here we show that Acanthamoeba keratitis is profoundly affected by mannosy

164 s are among the most ubiquitous amoebae, yet Acanthamoeba keratitis is remarkably rare.

165 The unexplained persistence of the Acanthamoeba keratitis outbreak in the United States, cl

166 or for case contamination among Fusarium and Acanthamoeba keratitis patients.

167 tis, and 115 patients with laboratory-proven acanthamoeba keratitis seen at Aravind Eye Hospital, Mad

168 ifferentiating features were more common for acanthamoeba keratitis than for bacterial or fungal kera

169 tex beads induces a remarkable resistance to Acanthamoeba keratitis that is largely, if not entirely,

170 oscopy could be useful in cases of fungal or acanthamoeba keratitis to determine the depth of infecti

171 Acanthamoeba keratitis was defined as the presence of AK

172 Acanthamoeba keratitis was diagnosed on microbiological

173 bacterial or fungal keratitis, patients with acanthamoeba keratitis were more likely to be younger an

174 s adverse events, particularly bacterial and Acanthamoeba keratitis while using these lenses, althoug

175 with fungal keratitis, and 93 patients with acanthamoeba keratitis who had medical records available

176 dies reporting resolution or modification of Acanthamoeba keratitis without specific antiacanthamoeba

177 Acanthamoeba keratitis, a rare eye disease primarily aff

178 The soil amoebae Acanthamoeba causes Acanthamoeba keratitis, a severe sight-threatening infec

179 ial keratitis, epithelial regeneration line, Acanthamoeba keratitis, mucus plaque keratopathy, medica

180 his may provide new treatment modalities for Acanthamoeba keratitis.

181 reen new anti-infectives in the treatment of Acanthamoeba keratitis.

182 ould test the validity of this treatment for Acanthamoeba keratitis.

183 corneal scrapings from bacterial, viral, or Acanthamoeba keratitis.

184 a) inhibitors may be a therapeutic target in Acanthamoeba keratitis.

185 al-time PCR assays could be used to diagnose Acanthamoeba keratitis.

186 P-133 produce an additive protection against Acanthamoeba keratitis.

187 ubsequent steps of the pathogenic cascade of Acanthamoeba keratitis.

188 hat mediate latex bead-induced resistance to Acanthamoeba keratitis.

189 astellanii antigens fails to protect against Acanthamoeba keratitis.

190 innate immune apparatus in the resistance to Acanthamoeba keratitis.

191 ils in latex-bead-induced protection against Acanthamoeba keratitis.

192 ge amounts of mannose and is associated with Acanthamoeba keratitis.

193 o chlorhexidine, a drug widely used to treat Acanthamoeba keratitis.

194 ubsequent steps of the pathogenic cascade of Acanthamoeba keratitis.

195 nt an important immunotherapeutic target for Acanthamoeba keratitis.

196 4 patients underwent diagnostic testing for Acanthamoeba keratitis.

197 a, such as herpes simplex virus keratitis or Acanthamoeba keratitis.

198 Gel filtration experiments revealed that the Acanthamoeba lectin is a approximately 400-kDa protein t

199 hamoeba polyphaga, Acanthamoeba castellanii, Acanthamoeba lenticulata, Vermamoeba vermiformis and Dic

200 a castellanii, Acanthamoeba culbertsoni, and Acanthamoeba lenticulata.

201 In summary, we have characterized Acanthamoeba MBP and have shown that it is a major virul

202 (ii). polyclonal antibodies prepared against Acanthamoeba MBP bound to the recombinant protein.

203 nd sequencing experiments indicated that the Acanthamoeba MBP gene is composed of 6 exons and 5 intro

204 tion with our published studies showing that Acanthamoeba MBP is a major virulence protein suggest th

205 However, direct evidence showing that Acanthamoeba MBP is a virulence protein has been lacking

206 ith high affinity for mannose, revealed that Acanthamoeba MBP is itself a mannose-containing glycopro

207 aining, it was conclusively established that Acanthamoeba MBP is located on the surface membranes of

208 Hexosamine analysis revealed that Acanthamoeba MBP lacks detectable levels of GalNAc, sugg

209 ntibodies prepared against affinity-purified Acanthamoeba MBP markedly inhibit the adhesion of parasi

210 The most striking feature of the Acanthamoeba MBP sequence is the presence of a cysteine-

211 here the isolation and molecular cloning of Acanthamoeba MBP.

212 Acanthamoeba move directionally in a three-dimensional (

213 In six cases, identical Acanthamoeba mtDNA profiles were found for the clinical

214 The 466-aa tail of the heavy chain of Acanthamoeba myosin IC (AMIC) comprises an N-terminal 22

215 The tail of Acanthamoeba myosin IC (AMIC) has a basic region (BR), w

216 Acanthamoeba myosin IC (AMIC) is a single-headed myosin

217 Previously, we found that Acanthamoeba myosin IC binds to acidic phospholipids in

218 Acanthamoeba myosin II (AMII) has two heavy chains endin

219 ed previously that only filamentous forms of Acanthamoeba myosin II have actin-activated MgATPase act

220 al, we show that two nonfilamentous forms of Acanthamoeba myosin II, heavy meromyosin and myosin subf

221 Acanthamoeba myosin-II forms bipolar octamers by three s

222 ggest that the first step in the assembly of Acanthamoeba myosin-II is anti-parallel dimerization of

223 uncation constructs and point mutants of the Acanthamoeba myosin-II tail to delineate the structural

224 ute bacterial (n = 23), fungal (n = 13), and Acanthamoeba (n = 17) keratitis, and in 20 normal eyes,

225 nosis of bacterial (n=28), fungal (n=15), or Acanthamoeba (n=13) keratitis were included in the study

226 pes simplex virus, n = 16; bacteria, n = 10; Acanthamoeba, n = 5), with healthy endothelium.

227 ebae reproduce sexually, many amoebae (e.g., Acanthamoeba, Naegleria) reproduce asexually and therefo

228 Mature cysts of Acanthamoeba not evident in the inocula were observed in

229 this work was to investigate the effects of Acanthamoeba on human monocytes/macrophages during the e

230 in this study we investigated the effects of Acanthamoeba on the activation of resting macrophages.

231 iral, or immune keratitis featuring negative Acanthamoeba PCR results (control group).

232 ose-induced cytopathic protein (MIP-133) and Acanthamoeba plasminogen activator (aPA) play key roles

233 e simultaneous discovery of a giant virus of Acanthamoeba polyphaga (Lentille virus) that contains an

234 ated to Mycobacterium spp. was identified in Acanthamoeba polyphaga 50495.

235 We cultured, on Acanthamoeba polyphaga amoebae, pulmonary samples from 1

236 who failed to mount a serologic response to Acanthamoeba polyphaga is presented.

237 The genome sequence of the giant virus Acanthamoeba polyphaga mimivirus revealed the presence o

238 all isolates of Acanthamoeba castellanii and Acanthamoeba polyphaga tested.

239 Although Acanthamoeba polyphaga that is sensitive to multiple ant

240 uster resulted in virulence towards amoebae (Acanthamoeba polyphaga) and reduced colonization of plan

241 Here, we show that five FLA species (Acanthamoeba polyphaga, Acanthamoeba castellanii, Acanth

242 ogenic species, Acanthamoeba castellanii and Acanthamoeba polyphaga, and has been validated by compar

243 ular proliferation within human macrophages, Acanthamoeba polyphaga, and the ciliate Tetrahymena pyri

244 Mimivirus, a parasite of Acanthamoeba polyphaga, is the largest DNA virus known;

245 ed macrophages (hMDMs), U937 macrophages and Acanthamoeba polyphaga.

246 ithin human monocyte-derived macrophages and Acanthamoeba polyphaga.

247 r up to 8 h postinfection of macrophages and Acanthamoeba polyphaga.

248 ins produced by bacteria internalized by the Acanthamoeba predator are cytolethal; the presence of pu

249 ages cocultured with the clinical isolate of Acanthamoeba produced significantly less IL-12 and IL-6

250 complete description of sterol metabolism in Acanthamoeba, provide a putative framework for their fur

251 Acanthamoeba sclerokeratitis is associated with poor cli

252 or a chicken monoclonal antibody against the Acanthamoeba serine protease MIP-133.

253 with MIP-133 before and after infection with Acanthamoeba significantly reduced the severity of corne

254 s two parasites (Balamuthia mandrillaris and Acanthamoeba), six bacterial pathogens (Streptococcus pn

255 nation showed fungi or cysts consistent with Acanthamoeba sp.).

256 ed fibrils surrounding their capsids, infect Acanthamoeba sp., which are ubiquitous unicellular eukar

257 Acanthamoeba species are among the most ubiquitous amoeb

258 Acanthamoeba species are infected by the largest known D

259 Acanthamoeba species can cause keratitis, a painful visi

260 Two different strains of Acanthamoeba species were tested identically.

261 Pathogenic free-living amoebae, such as Acanthamoeba species, Balamuthia mandrillaris, and Naegl

262 A virus identified so far, infecting several Acanthamoeba species.

263 more effective than edelfosine against both Acanthamoeba species.

264 es of much needed new antimicrobials against Acanthamoeba species.

265 ns wearers, is caused by free-living amebae, Acanthamoeba species.

266 It is thought that Acanthamoeba-specific IgA antibodies present in mucosal

267 d in pathogenic and nonpathogenic strains of Acanthamoeba spp.

268 ocyte-derived macrophages (hMDMs) but not in Acanthamoeba spp.

269 nt nucleotide identity with endosymbionts of Acanthamoeba spp. (order Chlamydiales).

270 lla and mycobacteria), and two amoeba hosts (Acanthamoeba spp. and Hartmanella vermiformis).

271 he, but is dispensable for growth within the Acanthamoeba spp. that synthesize the aromatic amino aci

272 um intracellulare, Pseudmonas aeruginosa, or Acanthamoeba spp.) during the entire course of the study

273 Of the isolated amoebae, 31 were Acanthamoeba spp., 21 were Hartmannella vermiformis, 13

274 tions of Legionella spp., M. intracellulare, Acanthamoeba spp., and M. avium peaked during the dry se

275 e-living amoebae, such as Naegleria fowleri, Acanthamoeba spp., and Vermamoeba spp., have been identi

276 more, we demonstrate for the first time that Acanthamoeba stimulates IL-10 production in human innate

277 annot achieve eradication in the 2 different Acanthamoeba strains examined.

278 Both Acanthamoeba strains induced a proinflammatory macrophag

279 Acanthamoeba strains that bound avidly to host cells and

280 f Legionella, reduction in P. aeruginosa and Acanthamoeba) suggest a temporally dynamic drinking wate

281 ATCC and clinical strains of Acanthamoeba that failed to be detected by certain indiv

282 For Acanthamoeba, the pooled sensitivity was 88.2% (95% CI:

283 his assay may be helpful for guiding topical Acanthamoeba therapy and providing a practical method to

284 Acanthamoeba trophozoite migration is also voltage-depen

285 method for determining the susceptibility of Acanthamoeba trophozoites and cysts to contact lens care

286 We showed that both Acanthamoeba trophozoites and soluble amoebic products i

287 enesis of Acanthamoeba keratitis begins when Acanthamoeba trophozoites bind specifically to mannosyla

288 ig corneas and was used to determine whether Acanthamoeba trophozoites could penetrate this membrane

289 Acanthamoeba trophozoites move at random in the absence

290 Acanthamoeba trophozoites move directionally in response

291 We investigated the in vitro response of Acanthamoeba trophozoites to electric fields (EFs).

292 ation in a three-dimensional culture system, Acanthamoeba trophozoites were cultured in agar, exposed

293 phages in the recognition of and response to Acanthamoeba trophozoites.

294 ect 0.7 Acanthamoeba cysts/10 microl and 2.3 Acanthamoeba trophozoites/10 microl by both real-time PC

295 a found in drinking water networks, that is, Acanthamoeba, Vermamoeba, Echinamoeba, and Protacanthamo

296 ia-like endosymbiont has previously enhanced Acanthamoeba virulence in vitro.

297 lasses of bacterial endosymbionts attenuated Acanthamoeba virulence, as indicated by decreased observ

298 of 3 well-characterized clinical strains of Acanthamoeba were exposed at 0.5, 2.0, 3.5, 5.0, and 6.5

299 FLA, including Acanthamoeba, were isolated from 24 (89%) of 27 homes, a

300 f trophozoites of four different isolates of Acanthamoeba with various degrees of in vitro pathogenic