ライフサイエンスコーパス: Alexander

1 Alexander cells have integrated the hepatitis B surface

2 Alexander D. Langmuir is credited with articulating the

3 Alexander Disease (AxD) is a primary disorder of astrocy

4 Alexander disease (AxD) is a primary disorder of astrocy

5 Alexander disease (AxD) is a primary genetic disorder of

6 Alexander disease (AxD) is a rare but fatal neurological

7 Alexander disease (AxD) is a rare neurodegenerative diso

8 Alexander disease (AxD) is the only known human patholog

9 Alexander disease is a fatal neurodegenerative disease c

10 Alexander disease is a fatal neurodegenerative disorder

11 Alexander disease is a progressive, usually fatal neurol

12 Alexander disease is a rare disorder of the central nerv

13 Alexander disease therefore represents the first example

14 Alexander Langmuir, head of the Epidemiology Branch, red

15 Alexander Skutch proposed 50 years ago that higher nest

16 Alexander Tsai and colleagues highlight the complex rela

17 ttendance was 10 acupuncture sessions and 14 Alexander lessons.

18 In March 1800, Alexander von Humboldt observed the extraordinary specta

19 In 1802, Alexander von Humboldt ascended the Chimborazo volcano i

20 In 1903, Alexander Graham Bell developed a design principle to ge

21 In 1949, Alexander Langmuir became the first chief epidemiologist

22 However, studies using PRF/PLC/5 (Alexander) cells revealed that CT-2584 is cytotoxic by a

23 To honor Academician Alexander Abramovitch Krasnovsky, we present here an edu

24 National Institute on Aging, Alexander Family Professorship of Alzheimer's Disease Re

25 More than 70 years ago, Alexander Fleming discovered lysozyme and proposed that

26 US National Institute on Aging and Alexander Family Professorship of Alzheimer's Disease Re

27 hose that cause some corneal dystrophies and Alexander disease, than previously hypothesized and that

28 l of multiple sclerosis, brain ischemia, and Alexander disease.

29 Acupuncture sessions and Alexander Technique lessons both led to significant redu

30 However, as Alexander explains in his Perspective, a new fossil find

31 Since being discovered by Alexander Bell, photoacoustics may again be seeing major

32 Topology was identified by Alexander and Vassiliev degree 2 invariants.

33 rediction of response-outcome (PRO) model by Alexander and Brown claims that the mediofrontal cortex

34 The third edge was already recognized by Alexander Fleming in 1945 in his Nobel acceptance speech

35 rotein has uncovered little that would cause Alexander the Great to reach for his sword.

36 are termed Rosenthal fibers and characterize Alexander disease, a leukodystrophy caused by heterozygo

37 samples from patients representing different Alexander disease phenotypes revealed that most cases ar

38 (GFAP) lead to the rare and fatal disorder, Alexander disease (AxD).

39 ead to the fatal neurodegenerative disorder, Alexander disease (AxD), which is characterized by cytop

40 rt for their claimed Greek descent following Alexander III of Macedon's invasion of this region, and

41 aseline were 32% for acupuncture and 31% for Alexander lessons.

42 ) (P = 0.009) and 3.79 percentage points for Alexander lessons (CI, 0.91 to 6.66 percentage points) (

43 ry alteration in GFAP may be responsible for Alexander disease.

44 t the Department of Ophthalmology, Friedrich-Alexander-University Erlangen-Nurnberg, Erlangen (FAU),

45 del mice and in postmortem brain tissue from Alexander disease patients, and that blocking muscarinic

46 y directed mutagenesis and expressed in HCC (Alexander and SK-Hep-1) and CGC (TFK1) cells.

47 uscarinic cholinergic receptor expression in Alexander disease model mice and in postmortem brain tis

48 rotein deposits known as Rosenthal fibers in Alexander disease.

49 ible for the massive accumulation of GFAP in Alexander disease remain unclear.

50 y acidic protein (GFAP), which is mutated in Alexander disease (Y242D).

51 glial fibrillary acidic protein mutations in Alexander disease, we analyzed 41 new patients and anoth

52 and disorders of the CNS, and also occur in Alexander disease where the initial insult is a mutation

53 e role of glial fibrillary acidic protein in Alexander disease and of proteolipid protein in hypomyel

54 s, and that blocking muscarinic receptors in Alexander disease model mice reduces oxidative stress, e

55 ed clinical symptoms and oxidative stress in Alexander disease model flies and mice.

56 gnaling as a potential therapeutic target in Alexander disease, and possibly in other gliopathic diso

57 tic target for reducing cellular toxicity in Alexander disease, and possibly other neurodegenerative

58 In this issue of the JCI, Alexander et al. report that mice lacking the receptor f

59 rotein (GFAP), cause the rare leukodystrophy Alexander disease (AxD).

60 ter the poisoning and subsequent death of Mr Alexander Litvinenko in London, UK, in 2006.

61 lary acidic protein (GFAP), in astrocytes of Alexander disease (AxD) impairs proteasome function in a

62 We have been studying the astrocytes of Alexander disease (AxD), which is caused by heterozygous

63 In all the cases of Alexander's disease examined, strong immunolabeling of R

64 mmunohistochemically examined three cases of Alexander's disease using antibodies to a lysine-derived

65 King Philip II was the father of Alexander the Great.

66 and antigenically to the Rosenthal fibers of Alexander's disease.

67 The pathological hallmark of all forms of Alexander disease is the presence of Rosenthal fibers, c

68 ditions and are the histological hallmark of Alexander's disease.

69 ngs thus establish a simple genetic model of Alexander disease and further identify cellular pathways

70 We have created a model of Alexander disease in Drosophila by expressing disease-li

71 Here we use a simple genetic model of Alexander disease, a progressive and severe human degene

72 Using a simple Drosophila model of Alexander disease, we performed a moderate throughput ch

73 Nrf2 would be beneficial in a mouse model of Alexander disease.

74 refore, by inference, in the pathogenesis of Alexander's disease.

75 tion of RF as well as in the pathogenesis of Alexander's disease.

76 family with PAPT, raising the possibility of Alexander's disease.

77 Intelligence Service (EIS) was the vision of Alexander Langmuir, who developed a program with a vital

78 12 acupuncture sessions or 20 one-to-one Alexander lessons (both 600 minutes total) plus usual ca

79 points [CI, 2.31 to 4.38 percentage points]; Alexander lessons, 3.33 percentage points [CI, 2.22 to 4

80 Richard Alexander has argued that moral systems derive from indi

81 the enigmatic brown bears native to Alaska's Alexander Archipelago, we estimate that not only their m

82 -Franch and colleagues, Lorenz von Seidlein, Alexander Kekule, and Daniel Strickman discuss the impor

83 Almost 90 years have passed since Alexander Fleming discovered the antimicrobial activity

84 The results support the notion that Alexander's disease is a disorder of astrocytes, and pro

85 licon nitride AFM tip were measured, and the Alexander and de Gennes model of steric repulsion betwee

86 rom the Admiralty and Baranof islands of the Alexander Archipelago of southeastern Alaska and Kodiak

87 ime, two-parameter unconstrained fits of the Alexander-de Gennes brush scaling laws to the Kenworthy

88 urrent implementation of the server uses the Alexander polynomial to detect knots.

89 We delineate conditions where the Alexander-de Gennes theory of polymer brushes successful

90 We have asked two experts, Thomas Alexander of Summa Health Care, who has adopted an IGRA

91 Mutations in the GFAP gene lead to Alexander disease (AxD), a rare, fatal neurological diso

92 Here we use Alexander disease, a serious degenerative neurological d

93 Infants with Alexander disease develop a leukoencephalopathy with mac