ライフサイエンスコーパス: Apicomplexa

1 logy associated with parasites of the phylum Apicomplexa.

2 at are both synthesized and scavenged by the Apicomplexa.

3 ent within protozoan parasites of the phylum Apicomplexa.

4 e, are unique to C. parvum within the phylum Apicomplexa.

5 nd directionality of gliding motility in the Apicomplexa.

6 nus arose from an early branching within the Apicomplexa.

7 data from protozoan parasites in the phylum Apicomplexa.

8 contents appears to be ubiquitous among the Apicomplexa.

9 m and potential virulence for this and other apicomplexa.

10 ate intracellular pathogen within the phylum Apicomplexa.

11 uences that are apparently restricted to the Apicomplexa.

12 us protein (TRAP) that has homologs in other Apicomplexa.

13 call this new organelle the secondary ER of apicomplexa.

14 rotein EXP2 and conserved across PV-residing Apicomplexa.

15 p3 in early-branching protozoa in the phylum Apicomplexa.

16 a CTLD-containing protein in protozoa and in Apicomplexa.

17 minent intracellular parasites of the phylum Apicomplexa.

18 for fundamental and applied research on the Apicomplexa.

19 as an additional death promoting pathway in Apicomplexa.

20 s, such as plants or parasites of the phylum Apicomplexa.

21 he regulated disassembly of filaments in the Apicomplexa.

22 a protozoan parasite belonging to the phylum Apicomplexa.

23 verged member of the Tic20 protein family in Apicomplexa.

24 eukaryotic cells before the early diverging Apicomplexa.

25 ommon regulatory machinery across the phylum Apicomplexa.

26 re secretory organelles unique to the phylum Apicomplexa.

27 ate of recombination commensurate with other Apicomplexa.

28 ria, identifying a new protein family in the Apicomplexa.

29 ecretory proteins in parasites of the phylum Apicomplexa.

30 site conserved in similar proteins of other Apicomplexa.

31 at this is a widely conserved feature of the Apicomplexa.

32 Toxoplasma gondii is a member of the phylum Apicomplexa, a diverse group of intracellular parasites

33 We propose that Apicomplexa abandoned flagella for most stages yet retai

34 gether, these observations indicate that the Apicomplexa acquired a plastid by secondary endosymbiosi

35 cating conservation of Sec insertion between Apicomplexa and animals.

36 coplast exists in most members of the phylum Apicomplexa and has its own genome along with organelle-

37 novel biological features of members of the Apicomplexa and hence offer great potential for biologic

38 Toxoplasma gondii belongs to the phylum Apicomplexa and is an important cause of congenital dise

39 e considerable phylogenetic distance between Apicomplexa and other Eukaryotes is reflected by profoun

40 ondii are widely studied parasites in phylum Apicomplexa and the etiological agents of severe human m

41 tabolic pathways among members of the phylum Apicomplexa and these parasites and their human hosts ar

42 plasmic transport in these parasites (phylum Apicomplexa), and this study marks the first demonstrate

43 identified a clade of R2 subunits unique to Apicomplexa, and determined its phylogenetic position.

44 ed rhomboids have now been identified within Apicomplexa, and one Toxoplasma rhomboid has been locali

45 The Apicomplexa are a large phylum which contains various pa

46 apical and surface-exposed zoite Ags of the Apicomplexa are critical to infectivity and targets of p

47 suggest that secreted kinases unique to the Apicomplexa are crucial in the host-pathogen interaction

48 Parasites of the phylum Apicomplexa are highly successful pathogens of humans an

49 Apicomplexa are important pathogens that include the cau

50 Apicomplexa are intracellular parasites that cause impor

51 Many protozoans of the phylum Apicomplexa are invasive parasites that exhibit a substr

52 Apicomplexa are known to contain greatly reduced organel

53 Apicomplexa are obligate intracellular parasites that ca

54 The apicomplexa are parasitic protozoa that are responsible

55 Apicomplexa are parasitic protozoa that cause important

56 Apicomplexa are protist parasites of tremendous medical

57 The approximately 6000 species in phylum Apicomplexa are single-celled obligate intracellular par

58 Members of the eukaryotic phylum Apicomplexa are the cause of important human diseases in

59 arvum, C. meleagridis and C. hominis (phylum Apicomplexa) are enteric pathogens of humans.

60 Apicomplexa belong to the Alveolata, a group that also i

61 nt in some members of the Kinetoplastida and Apicomplexa, but present in Toxoplasma gondii.

62 bligate intracellular parasite of the phylum Apicomplexa, can cause severe disease in humans with an

63 , and other parasitic protists of the Phylum Apicomplexa, carry a plastid-like genome with greatly re

64 Parasites of the phylum Apicomplexa cause substantial morbidity, mortality and e

65 an intraerythrocytic parasite of the phylum Apicomplexa, causes a febrile syndrome similar to malari

66 ribution of the insertions--which we find in apicomplexa, ciliates, land plants, and charophyte green

67 NA gene sequences of Neospora spp. and other apicomplexa coccidia, oligonucleotide primers COC-1 and

68 Phylum Apicomplexa comprises a large group of obligate intracel

69 The phylum Apicomplexa comprises numerous veterinary and medically

70 The Phylum Apicomplexa comprises thousands of obligate intracellula

71 Protozoan parasites of the phylum Apicomplexa contain three genetic elements: the nuclear

72 In the Apicomplexa, convergent evolution of an unusual LDH from

73 The apicoplast and the mitochondrion of Apicomplexa cooperate in providing essential metabolites

74 A robust forward genetic model for Apicomplexa could greatly enhance functional analysis of

75 Apicomplexa division involves several distinct phases sh

76 and human pathogens, belonging to the phylum Apicomplexa, employs a novel form of motility, known as

77 The eukaryotic phylum Apicomplexa encompasses thousands of obligate intracellu

78 Apicomplexa evolved from single celled flagellated algae

79 Apicomplexa exhibit a unique form of substrate-dependent

80 human toxoplasmosis, Babesia belongs to the Apicomplexa family.

81 domains emerged from an ancient transfer to Apicomplexa from metazoan hosts.

82 nal molecular characteristics distinguishing Apicomplexa from other eukaryotes for which complete gen

83 onstrate that TRAP-related proteins in other Apicomplexa fulfill the same function and that their cyt

84 Application of kdetrees to a set of Apicomplexa genes identified several unreliable sequence

85 Plasmodium sporozoites, and likely in other Apicomplexa, gliding locomotion and cell invasion have a

86 ntroduced hemosporidian (malaria) parasites (Apicomplexa: Haemosporida) have hastened the extinction

87 The malaria parasites (Apicomplexa: Haemosporida) of birds are believed to have

88 Protozoan parasites of the phylum Apicomplexa harbour a chloroplast-like organelle, the ap

89 iconic representatives, the protistan phylum Apicomplexa has long been defined as a group composed en

90 bligate intracellular parasite of the phylum Apicomplexa, has the unusual ability to infect virtually

91 sive gregarine gut parasites (Microsporidia, Apicomplexa) have reduced flight-muscle performance, an

92 llular parasites, which belong to the phylum Apicomplexa, have developed mechanisms to exploit their

93 geted protein determine their destination in Apicomplexa in a way similar to mammalian cells.

94 Parasites of the phylum Apicomplexa include many important human and veterinary

95 The phylum Apicomplexa includes parasites responsible for global sc

96 The phylum Apicomplexa includes thousands of species of obligate in

97 ndii and related parasites within the Phylum Apicomplexa (including Plasmodium spp., the causative ag

98 All parasites in the phylum Apicomplexa, including Toxoplasma gondii and Plasmodium

99 that occurred in the evolution of the phylum Apicomplexa--including the gain and loss of photosynthes

100 Enolase genes from land plants and apicomplexa (intracellular parasites, including the mala

101 jor goals, both for the understanding of the Apicomplexa invasion process and for the vaccine potenti

102 Apicomplexa is a large phylum of intracellular parasites

103 ligate intracellular protozoan of the phylum Apicomplexa, is estimated to infect over a billion peopl

104 refore this enzyme, conserved throughout the Apicomplexa, is likely to have been obtained via lateral

105 ed transcription Elongator complex; however, Apicomplexa lack all other Elongator subunits, suggestin

106 ontext of regulated transcriptional control (apicomplexa) or in its absence (kinetoplastids).

107 to be essential for the perpetuation of two Apicomplexa parasite genera, Plasmodium and Toxoplasma,

108 A modular approach to synthesize anti-Apicomplexa parasite inhibitors was developed that takes

109 rofolate reductase (TS-DHFR) enzyme from the apicomplexa parasite, Cryptosporidium hominis.

110 or transient localization on the surface of Apicomplexa parasites are of particular interest for the

111 ural factors that govern selectivity between Apicomplexa parasites such as Toxoplasma and Plasmodium

112 letely novel in biology and is only found in Apicomplexa parasites.

113 ermine genome organization and expression in Apicomplexa parasites.

114 eomes and Sec insertion systems in protozoan Apicomplexa parasites.

115 Among the Apicomplexa phylum of obligate intracellular parasites,

116 d by parasites of the obligate intracellular Apicomplexa phylum the most deadly of which, Plasmodium

117 Parasites of the Apicomplexa phylum use an actomyosin motor to drive inva

118 Parasites of the Apicomplexa phylum, such as Plasmodium spp. and Toxoplas

119 identified in protozoan parasites within the Apicomplexa phylum.

120 This Apicomplexa protein-designated tRip (tRNA import protein

121 They are members of the Apicomplexa--protozoan pathogens that invade host cells

122 Eukaryotic parasites belonging to the phylum Apicomplexa provide an excellent example to support this

123 caformis, which share a common ancestry with Apicomplexa, provided an opportunity to study possibly a

124 Apicomplexa retain a plastid organelle (the apicoplast)

125 subtilases are present in genomes of all the Apicomplexa sequenced to date, subtilases may represent

126 A family of apicomplexa-specific proteins containing AP2 DNA-binding

127 human and veterinary pathogens in the phylum Apicomplexa, such as Plasmodium, Eimeria, and Cryptospor

128 ellular proteoglycans of gliding diatoms and apicomplexa, suggesting that slime deposition is a gener

129 Sarcocystis neurona is a member of the Apicomplexa that causes myelitis and encephalitis in hor

130 te Toxoplasma gondii, a member of the phylum Apicomplexa that includes Plasmodium spp., is one of the

131 Toxoplasma gondii is a member of the phylum Apicomplexa that includes several important human pathog

132 gondii is a protozoan pathogen in the phylum Apicomplexa that resides within an intracellular parasit

133 As APH is conserved in Apicomplexa, these findings highlight a potentially wide

134 er members of the TRAP family of proteins in Apicomplexa, they may account for the capacity of these

135 gae, as well as ciliates (close relatives of apicomplexa), to determine whether lateral transfer can

136 sp. and Haemoproteus columbae) and two other Apicomplexa (Toxoplasma gondii and Theileria parva).

137 er members of the medically important phylum Apicomplexa, Toxoplasma gondii is an obligate intracellu

138 on of rhoptries from one of the best studied Apicomplexa, Toxoplasma gondii, and we carried out a det

139 rent repertoire of rhomboid-like proteins in Apicomplexa using a nomenclature based on phylogenetic a

140 n the conservation of this protein among the Apicomplexa, we assessed whether the Plasmodium falcipar

141 everal important parasites within the phylum Apicomplexa were undertaken for the purpose of gene disc

142 bligate intracellular parasite of the phylum Apicomplexa, which also includes other parasites of clin

143 plasma is a protozoan parasite in the phylum Apicomplexa, which contains a number of medically import

144 successful protozoan parasite in the phylum Apicomplexa, which contains numerous animal and human pa

145 a gondii is the model parasite of the phylum Apicomplexa, which contains numerous obligate intracellu

146 a gondii is the model parasite of the phylum Apicomplexa, which contains obligate intracellular paras

147 We identified an unusual gene in Apicomplexa with a coding sequence for membrane-docking

148 n contributes to key biological processes in Apicomplexa with the recent palmitome of the malaria par