ライフサイエンスコーパス: B. suis

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1 B. suis primarily infects pigs and is pathogenic to huma

2 avillous trophoblasts (EVTs), B. abortus and B. suis replicated within single-membrane acidic lysosom

3 ents were shared between only B. abortus and B. suis, B. abortus shared more fragments and had fewer

4 al isolates (no species name), B. canis, and B. suis, confirmed that all but the latter two species c

5 ucella abortus, B. melitensis, B. canis, and B. suis.

6 Brucella abortus, B. melitensis, and B. suis are pathogenic to humans, whereas B. ovis and B.

7 ersistence of B. abortus, B. melitensis, and B. suis in mice up to 4 weeks after infection, since del

8 n, and unlike B. abortus, B. melitensis, and B. suis, B. neotomae has not been observed to infect hum

9 ella species: B. abortus, B. melitensis, and B. suis.

10 ests of Brucella abortus, B. melitensis, and B. suis.

11 of infected macrophages and rough attenuated B. suis strain VTRS1 (a vaccine candidate) induced stron

12 Extensive gene synteny between B. suis chromosome 1 and the genome of the plant symbion

13 ts previously identified as unique to either B. suis or B. melitensis were present in the B. abortus

14 sed of Wb and S708 phages that are lytic for B. suis, B. abortus and B. neotomae.

15 s share a common ancestor that diverged from B. suis.

16 Furthermore, B. suis was determined to be paraphyletic in our analyse

17 We have investigated how B. suis and B. melitensis enter human monocytes and in w

18 B. abortus, B. melitensis, B. suis, and B. canis produced identical PCR interspace

19 lla species-Brucella abortus, B. melitensis, B. suis, B. canis, and B. ovis-using whole-genome compar

20 ermore, B. melitensis but not B. abortus nor B. suis interfered with the invasive capacity of EVT-lik

21 ency with cell morphology and attenuation of B. suis.

22 Comparison of B. suis with Brucella melitensis has defined a finite se

23 Genome sequencing of B. suis and B. melitensis revealed that both are complet

24 necessary for the intracellular survival of B. suis.

25 Only B. suis 1330 appears to have an intact beta-ketoadipate

26 Only B. suis and B. canis isolates clustered together and cou

27 enge with virulent B. abortus strain 2308 or B. suis strain 1330 but no protection against B. meliten

28 field isolates compared to the newly revised B. suis 1330 reference genome identified on average 13,

29 lassic infectious Brucella reference strain, B. suis 1330, was also used.

30 leen and liver, but were less efficient than B. suis 1330.

31 eotide polymorphisms with B. melitensis than B. suis.

32 We found that B. suis is a highly divergent clade with extensive intra

33 The B. suis CtpA protein shared up to 77% homology with CtpA

34 Analysis of the B. suis genome reveals transport and metabolic capabilit

35 In contrast to B. suis and B. melitensis, it was found that B. neotomae

36 Our studies showed that smooth virulent B. suis strain 1330 (S1330) prevented programmed cell de

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