ライフサイエンスコーパス: BN rat

1 athways in BN-J rats compared with wild-type BN rats.

2 n adult (3 months) and aged (24 months) F344/BN rats.

3 ectable in the vitreous, lens, and cornea of BN rats.

4 anin-like activity was 100-fold less than in BN rats.

5 oximately 1.5-fold higher in SD rats than in BN rats.

6 in magnitude and of shorter duration than in BN rats.

7 induced retinal neovascularization in SD and BN rats.

8 the F(2) progeny of BB(DR) and CIA-resistant BN rats.

9 it TNF-alpha bioactivity in virus-inoculated BN rats.

10 induced by laser treatment in Brown Norway (BN) rats.

11 Dahl Salt-Sensitive (DSS), and Brown Norway (BN) rats.

12 re harvested and purified from Brown-Norway (BN) rats.

13 selective COX-2 inhibitor) to Brown Norway (BN) rats.

14 reversed the renoprotective effects in SS.5(BN) rats.

15 susceptibility in DA/Bkl (DA) and BN/SsNHsd (BN) rats.

16 Male Wistar-Kyoto (WKY) and Brown Norway (BN) rats (11-12 weeks, n = 184) received an injection of

17 arizes our clinical and biochemical control (bNED) rates after conformal radiotherapy (RT).

18 ular brown adipose tissue (IBAT) from F344 x BN rats ages 3, 12, 18, 24, and 30 months (n = 8/age).

19 BN rats also had greater numbers of bronchiolar macropha

20 Given the unique T-helper-2 bias in BN rats, altered sympathetic-immune communication may be

21 e to compare virus-susceptible brown Norway (BN) rats and virus-resistant F344 rats and to determine

22 at) were administered periocularly in SD and BN rats, and celecoxib levels in these eye tissues were

23 r basis of the neuromodulatory deficiency in BN rats, and further suggest an important functional rol

24 peptide levels were significantly reduced in BN rats, and injections of the stable TRH analogue Talti

25 ble Han:SPRD(cy/+) and control Brown Norway (BN) rats, and performed a whole-genome scan in 182 PKD a

26 ive abilities of aging (24-month-old) F344 x BN rats are generally good, but are more vulnerable to t

27 in startle amplitude was seen in CRF-treated BN rats but not in CRF-treated WKY rats.

28 ed significant retinal neovascularization in BN rats but not in SD rats, as demonstrated by fluoresce

29 BN rats, but not BN/Ka rats, showed a 56% reduction in c

30 ormalized the ventilatory CO2 chemoreflex in BN rats, but TAL did not affect CO2 sensitivity in contr

31 A and the AT(2)-ant blocked these effects in BN rats, but the B(2)-ant did not.

32 nonreactivity was produced in Brown-Norway (BN) rats by transplantation of Lewis (LEW) liver, bone m

33 BN rat carotid bodies have naturally higher CO and lower

34 Reducing CO levels in BN rat carotid bodies increased H2S generation, restorin

35 In CRF-treated BN rats, clozapine-enhanced PPI.

36 upnoeic breathing and CO2 sensitivity in the BN rats compared to other rat strains.We measured ventil

37 d a 35% increase in fractional shortening in BN rats compared with a 16% increase in BN/Ka rats.

38 Celecoxib kinetics in the BN rat cornea can be described by a two-compartment (per

39 bronchiolitis at an early age, Brown Norway (BN) rats develop chronic airway dysfunction consisting o

40 In oxygen-induced retinopathy (OIR), BN rats developed retinal vascular hyperpermeability fro

41 In contrast, Brown Norway (BN) rats developed severe disease when immunized with RP

42 otocin (STZ)-induced diabetes, Brown Norway (BN) rats developed sustained vascular hyperpermeability

43 ry cancer when treated continuously with E2, BN rats did not develop palpable mammary cancer during t

44 Brown Norway (BN) rats exhibit an inherent and severe ventilatory inse

45 with Sprague-Dawley (SD) rats, Brown-Norway (BN) rats exhibit impaired carotid body O2 sensing and de

46 Brown Norway (BN) rats exhibit natural PPI deficits under certain para

47 In response to decreased flow, BN rats exhibited the smallest reduction in shear stress

48 ibited a smaller response, and Brown Norway (BN) rats exhibited the smallest response.

49 tuarial survival, disease-free survival, and bNED rates for the entire population were 80.5%, 70.0%,

50 Treg function and protects Themis1-deficient BN rats from spontaneous IBD development.

51 luding 32 that distinguish the Brown Norway (BN) rat from the other strains studied.

52 BN rats had increase pulmonary mRNA levels of TGF-beta 1

53 Virus-inoculated BN rats had increased TNF-alpha pulmonary mRNA levels (P

54 Brown Norway (BN) rats have a relatively specific deficit in CO2 sensi

55 Brown Norway (BN) rat heart or kidney allografts were transplanted int

56 Lewis rats transplanted with Brown Norway (BN) rat hearts were treated with different dose levels o

57 CO was examined in a fully allogeneic LEW to BN rat heterotopic heart transplantation (HHTx) model.

58 In BN rats, ICF was reduced and LVEF increased by AT(1)-ant

59 y, AA and W men had similar 5-year actuarial bNED rates in favorable (78% v 79%, P: = .91), intermedi

60 Administration of HgCl2 to naive BN rats induced marked autoantibody production, systemic

61 BN rats infected with virus developed increases in respi

62 haloperidol or clozapine to determine if the BN rat is a useful animal model with predictive validity

63 ventilatory insensitivity to hypercapnia in BN rats is due to altered raphe gene expression and the

64 the development of severe acute rejection in BN rat lungs, transplanted into LEW recipients.

65 This drug response profile suggests that the BN rat may be useful for detecting atypical antipsychoti

66 formation of 20-HETE from the Brown Norway (BN) rat onto the SS genetic background increased renal 2

67 49163 but not haloperidol facilitated PPI in BN rats (p < .001).

68 s) or morphological changes in Brown Norway (BN) rat pituitaries.

69 In contrast, BN rats pretreated with HgCl2-resistant allogeneic Lewis

70 BN rats received subcutaneous injections of either salin

71 They were compared with BN rats receiving either no pretreatment (naive) or FK50

72 odel of allergic lung disease, Brown Norway (BN) rats sensitized to HDM with alum and Bordetella pert

73 The BN rat sequence is the third complete mammalian genome t

74 The hyperoxia-treated BN rats showed a significant reduction in retinal PEDF,

75 BN rats showed less PPI than WKY rats, and neither antip

76 e ACI strain and the unrelated Brown Norway (BN) rat strain.

77 ere the genome sequence of the Brown Norway (BN) rat strain.

78 appa 1, and glutathione peroxidase) than the BN rat, suggesting that the LEW rat maintains cellular o

79 P = 0.001) and 2-fold (P = 0.0001) higher in BN rats than in SD rats.

80 We found that compared to the uninfected BN rat, the uninfected LEW rat has inherently higher tra

81 However, compared to the Brown Norway (BN) rat, the Lewis (LEW) rat is extremely resistant to T

82 Indeed, by contrast with BN rats, Themis1 deficiency in Lewis rats neither impair

83 Treg) function and predisposes Brown-Norway (BN) rats to spontaneous inflammatory bowel disease (IBD)

84 In HCC of genetically resistant BN rats, very low changes in the Mat1A:Mat2A ratio, CpG

85 elanin in choroid-RPE, sclera, and retina of BN rats were 200 +/- 30, 12 +/- 4, and 3 +/- 0.2 mug/mg

86 Higher CO levels in BN rats were associated with higher substrate affinity o

87 BN rats were low responders to PII and resistant to CIA

88 body weight and blood glucose, Brown Norway (BN) rats were divided into three groups.

89 BN/Ka rats and wild-type Brown Norway (BN) rats were exposed to local heart irradiation with a

90 Brown-Norway (BN) rats were pretreated with a syngeneic or allogeneic

91 ognostic risk category, the 5-year actuarial bNED rates were 78.7% for favorable, 57.7% for intermedi

92 ly attenuated laser-induced CNV formation in BN rats when initiated 3 days before or within 1 hour af

93 tional defects were also observed in LEW and BN rats, which are susceptible to induced autoimmunity,

94 pathetic activity/tone in male Brown Norway (BN) rats, which live longer and have a strikingly differ

95 We treated BN rats with haloperidol or clozapine to determine if th

96 ies of Sprague Dawley (SD) and Brown Norway (BN) rats with ischemia-induced retinal neovascularizatio

97 equencing analysis of the LEW rat versus the BN rat, with or without T. gondii infection, in order to