ライフサイエンスコーパス: Beckwith-Wiedemann syndrome

1 mprinting-related fetal overgrowth disorder, Beckwith-Wiedemann syndrome.

2 , with six patients not showing phenotype of Beckwith-Wiedemann syndrome.

3 , are both implicated in the pathogenesis of Beckwith-Wiedemann syndrome.

4 line balanced chromosomal rearrangements and Beckwith-Wiedemann syndrome.

5 diseases associated with imprinting such as Beckwith-Wiedemann syndrome.

6 imprinting region at 11p15.5 associated with Beckwith-Wiedemann syndrome.

7 nkage analysis to harbor the gene(s) for the Beckwith-Wiedemann syndrome.

8 Igf2 overexpression as a key determinant of Beckwith-Wiedemann syndrome.

9 ryonal tumors, including Wilms tumor, and in Beckwith-Wiedemann syndrome.

10 ilms' tumors, and tumors associated with the Beckwith-Wiedemann syndrome.

11 s in human p57(Kip2) have been implicated in Beckwith-Wiedemann syndrome, a disease that has also bee

12 ed expression of IGF2 has been implicated in Beckwith-Wiedemann syndrome, a human fetal overgrowth sy

13 se phenotypes are also seen in patients with Beckwith-Wiedemann syndrome, a pleiotropic hereditary di

14 them from the mutations of CDKN1C that cause Beckwith-Wiedemann syndrome, an overgrowth syndrome.

15 ome 11 at band p15.5, a region implicated in Beckwith-Wiedemann syndrome and a region of frequent los

16 s region to growth-related disorders such as Beckwith-Wiedemann syndrome and a variety of human cance

17 he mouse which will lead to animal models of Beckwith-Wiedemann syndrome and childhood tumours.

18 p57(Kip2) has been linked to Beckwith-Wiedemann syndrome and IMAGe syndrome in humans

19 e p57(Kip2) locus has been implicated in the Beckwith-Wiedemann syndrome and in the development of sp

20 their occasional occurrence in patients with Beckwith-Wiedemann syndrome and the case presented here

21 This locus is of specific interest, as Beckwith-Wiedemann syndrome and various childhood and ad

22 lead to serious imprinting disorders (e.g., Beckwith-Wiedemann syndrome) and is described in some ca

23 ART was found in registries of children with Beckwith-Wiedemann syndrome, Angelman syndrome, and reti

24 tes, a situation similar to that observed in Beckwith-Wiedemann syndrome, another imprinted disorder.

25 s associated with the developmental disorder Beckwith Wiedemann Syndrome (BWS) and with several cance

26 nd genotypes characterize the human disease, Beckwith--Wiedemann syndrome (BWS).

27 on and the two contrasting growth disorders, Beckwith-Wiedemann syndrome (BWS) and Silver-Russell syn

28 sociated with the human imprinting disorders Beckwith-Wiedemann syndrome (BWS) and Silver-Russell syn

29 imprinted status of the genes in the region, Beckwith-Wiedemann syndrome (BWS) and Wilms tumor are ea

30 Children with Beckwith-Wiedemann syndrome (BWS) are at increased risk

31 rearrangement breakpoints from patients with Beckwith-Wiedemann syndrome (BWS) have been mapped to 11

32 all report an unexpectedly high incidence of Beckwith-Wiedemann syndrome (BWS) in children conceived

33 Beckwith-Wiedemann syndrome (BWS) is a clinically variab

34 Beckwith-Wiedemann syndrome (BWS) is a congenital cancer

35 Beckwith-Wiedemann syndrome (BWS) is a fetal overgrowth

36 Beckwith-Wiedemann syndrome (BWS) is a hereditary human

37 Beckwith-Wiedemann syndrome (BWS) is a human stem cell d

38 Beckwith-Wiedemann syndrome (BWS) is a model human impri

39 Beckwith-Wiedemann syndrome (BWS) is an autosomal domina

40 The Beckwith-Wiedemann syndrome (BWS) is genetically linked

41 The Beckwith-Wiedemann syndrome (BWS) is marked by fetal org

42 mosome 11p15.1, centromeric to the imprinted Beckwith-Wiedemann syndrome (BWS) locus at 11p15.5.

43 1 that are associated with the human disease Beckwith-Wiedemann syndrome (BWS) may disrupt CDKN1C exp

44 ted with the Prader-Willi Syndrome (PWS) and Beckwith-Wiedemann Syndrome (BWS) where imprinting is kn

45 rearrangement breakpoints from patients with Beckwith-Wiedemann syndrome (BWS), a condition character

46 ncer and some hereditary diseases, including Beckwith-Wiedemann syndrome (BWS), a disorder of prenata

47 roblasts derived from patients with sporadic Beckwith-Wiedemann syndrome (BWS), a fetal overgrowth sy

48 enal defects, which are also features of the Beckwith-Wiedemann syndrome (BWS), a genetically complex

49 Disruption of imprinting leads to Beckwith-Wiedemann syndrome (BWS), an overgrowth and can

50 Beckwith-Wiedemann syndrome (BWS), which causes prenatal

51 chromosomal rearrangements in patients with Beckwith-Wiedemann syndrome (BWS), which causes prenatal

52 A related developmental disorder is Beckwith-Wiedemann syndrome (BWS), which increases risk

53 Beckwith-Wiedemann syndrome (BWS), which predisposes to

54 he normal kidney and tongue of patients with Beckwith-Wiedemann syndrome (BWS), which predisposes to

55 ted with a human overgrowth syndrome-namely, Beckwith-Wiedemann syndrome (BWS).

56 ergrowth and cancer predisposition condition Beckwith-Wiedemann syndrome (BWS).

57 of several pediatric and adult tumors and in Beckwith-Wiedemann syndrome (BWS).

58 und in the human foetal overgrowth syndrome, Beckwith-Wiedemann syndrome (BWS).

59 umor suppression and the cancer-predisposing Beckwith-Wiedemann syndrome (BWS).

60 associated with imprinting disorders such as Beckwith-Wiedemann syndrome (BWS).

61 ing guidelines for neurofibromatosis type 1, Beckwith-Wiedemann syndrome/ hemihypertrophy, and PTEN h

62 during childhood, including retinoblastoma, Beckwith-Wiedemann syndrome/idiopathic hemihypertrophy a

63 n of Igf2 results in most of the symptoms of Beckwith-Wiedemann syndrome, including prenatal overgrow

64 The Beckwith-Wiedemann syndrome is associated with the failu

65 implicated in the development of tumor-prone Beckwith-Wiedemann syndrome, is an effector molecule of

66 uency of ART conceptions among children with Beckwith-Wiedemann syndrome or Angelman syndrome caused

67 to develop rare epigenetic disorders such as Beckwith-Wiedemann Syndrome or Angelman Syndrome, both o

68 H analysis to map the breakpoints from three Beckwith-Wiedemann syndrome patients and a rhabdoid tumo

69 developing human brains and fibroblasts from Beckwith-Wiedemann syndrome patients.

70 n of human chromosome 11p15.5 is linked with Beckwith-Wiedemann syndrome that is associated with susc

71 ) we have found that the hereditary disorder Beckwith-Wiedemann syndrome, which predisposes to cancer

72 man chromosome 11p15.5, a region involved in Beckwith-Wiedemann syndrome, Wilms' tumor, and ovarian,