ライフサイエンスコーパス: C chemokine

1 ve to CC chemokines, which is unique to CX(3)C chemokines.

2 are a rich source of eosinophil-selective C-C chemokines.

3 decrease in the production of a number of C-C chemokines.

4 anced expression of a profile of C-C and C-X-C chemokines.

5 on the discrete target cell selectivity of C-C chemokines.

6 dus-2 also had unusual characteristics for C-C chemokines.

7 vivo chemoattractant activity of different C-C chemokines.

8 in response to these two closely related C-X-C chemokines.

9 t broadly recognizes human and murine CC and C chemokines.

10 kine genes, including TNFalpha, IL6, and C-X-C chemokine 10 (CXCL10) Exosomes engineered with elevate

11 tively, elevated serum concentrations of C-X-C chemokine 10 (CXCL10), a potent chemoattractant for an

12 ternative macrophage activation-associated C-C chemokine (AMAC) 1, or dendritic cell-derived C-C chem

13 XCL1 is a C chemokine and plays a specific and important role in t

14 Up-regulation of the three C-C chemokines and down-modulation of cell surface CCR5 we

15 helial cells (PMC) to release C-X-C and/or C-C chemokines and express adhesion molecules that initiat

16 he mammalian enzyme, fungal DppIVA cleaved C-C chemokines and GM-CSF.

17 h increased expression of genes encoding C-X-C chemokines and inflammatory cytokines when compared wi

18 ells from normal and HIV-1+ donors produce C-C chemokines and other unidentified factors that can inh

19 The data suggest that a dual mechanism of C-C chemokines and specific Abs may engage and down-modula

20 owed distinct differences in expression of C-C chemokines and their receptors between children with H

21 We hypothesized that IL-2 alters cytokine, C-C chemokine, and adhesion molecule expression in associa

22 rendered susceptible by neutralization of C-C chemokines, and addition of C-C chemokines did not con

23 tory protein-1alpha (MIP-1alpha) and other C-C chemokines, and that addition of anti-CD28 gives very

24 C-C chemokines are a structurally defined family of chemoa

25 These data indicate that multiple C-C chemokines are involved in the recruitment of particul

26 The C-C chemokines are major mediators of chemotaxis of monocy

27 C-X-C chemokines are potent chemoattractants that are believ

28 9 cells induced mRNA for several C-C and C-X-C chemokines as well as IFNs and GM-CSF.

29 We observed that Stx1 induces multiple C-X-C chemokines at the mRNA level, including interleukin-8

30 th the rapid but transient expression of C-X-C chemokines by epithelial cells infected with invasive

31 is overproduction of eosinophil-promoting C-C chemokines by sinus epithelium, perhaps driven in part

32 gulated expression of twelve C-X-C, C-C, and C-chemokines by human colon epithelial cells was charact

33 Previous studies have suggested that the C-C chemokine C10 is involved in the chronic stages of hos

34 Unlike other C-C chemokines, C10 levels in the peritoneal wash were inc

35 hage inflammatory protein [MIP]-1alpha), C-X-C chemokines (cytokine induced neutrophil chemoattractan

36 mokine (AMAC) 1, or dendritic cell-derived C-C chemokine (DCCK) 1).

37 ization of C-C chemokines, and addition of C-C chemokines did not consistently suppress endogenous vi

38 Its unique CX(3)C chemokine domain is attached to a 241-amino acid mucin

39 racterized by elevated IgE, Th2 cytokines, C-C chemokines, eosinophilic inflammation, and persistent

40 The C-C chemokine eotaxin is a potent chemoattractant for eosi

41 in response to i.p. administration of the C-C chemokine, eotaxin, was studied in vivo.

42 We show that the C-C chemokines, eotaxin and RANTES (regulated upon activat

43 man colonic epithelial cells produce the C-X-C chemokine epithelial neutrophil-activating peptide-78

44 Up-regulation of C-C chemokine expression characterizes allergic inflammati

45 hat Th1 and Th2 cytokines may regulate the C-C chemokine expression in PMCs and thus play a biologica

46 , we examined the effect of MIP-1 gamma, a C-C chemokine family member, on receptor activator of NF-k

47 he present study, we present data that the C-C chemokine family members may be a factor influencing t

48 possibility that the sole member of the CX(3)C chemokine family, fractalkine (fkn), induces angiogene

49 site regulation of MCP-1, a member of the C-C chemokine family, in a rat model of volume-overload co

50 chemoattractant (CINC), a member of the C-X-C chemokine family, in intact rats.

51 Fractalkine, the first member of the CX(3)C chemokine family, induces leukocyte chemotaxis through

52 RANTES, a member of the C-C chemokine family, is a potent chemoattractant for T ly

53 ological activities for this member of the C-C chemokine family.

54 R1 is a specific receptor for the novel CX(3)C chemokine fractalkine (FKN) (neurotactin).

55 chemokine lymphotactin, and the murine CX(3)C chemokine fractalkine with high affinity (K(d) = 1.6 t

56 2 cells may induce selective production of C-C chemokines from epithelium and indicate that glucocort

57 mine lung tissue for expression of CXC and C-C chemokine genes and bronchoalveolar lavage (BAL) fluid

58 determine the effect of Stx1 on various C-X-C chemokine genes in IECs.

59 ed in increased expression of both CXC and C-C chemokines genes in lung tissues.

60 MDM, we found that the production of the C-X-C chemokine growth-regulated oncogene alpha (GRO-alpha)

61 However, the human C-X-C chemokines growth-regulated oncogene (GROalpha) and IL

62 inophil activation; however, mRNA for this C-C chemokine has been shown to be constitutively expresse

63 The data suggest that C-X-C chemokines have important pathogenic potential in both

64 Hemofiltrate C-C chemokine (HCC)-1 is a recently cloned C-C chemokine t

65 The C-C chemokines human monocyte chemoattractant protein-1 an

66 lammation with increases in Th2 cytokines, C-C chemokines, IgE production, and mucous cell metaplasia

67 challenge with increases in Th2 cytokines, C-C chemokines, IgE production, and mucous cell metaplasia

68 Eotaxin is a C-C chemokine implicated in the recruitment of eosinophils

69 mononuclear cells (CBMC) to secrete these C-C chemokines in comparison to adult blood mononuclear ce

70 ease mRNA and protein levels of multiple C-X-C chemokines in IECs, with increased mRNA stability at l

71 The CCR5 Abs were complementary to the C-C chemokines in inhibiting HIV replication in vitro.

72 usly shown that Stxs can induce multiple C-X-C chemokines in intestinal epithelial cells in vitro, in

73 Binding assays using 125I-labeled C-C chemokines in mammalian cells indicated that CHEMR1 di

74 This study examined the role of C-X-C chemokines in PMN infiltration into P. aeruginosa-infe

75 Recent studies suggest a role for C-X-C chemokines in the pathogenesis of neutrophilic hepatit

76 G (monokine induced by IFNgamma) gene, a C-X-C chemokine, in mouse macrophages.

77 D4-specific chemoattractant, and RANTES, a C-C chemokine, in response to GD-specific IgG (GD-IgG).

78 cyte chemoattractant, IL-16, and RANTES, a C-C chemokine, in their fibroblasts.

79 Three C-C chemokines inhibit human immunodeficiency virus (HIV)

80 The expression and secretion of the C-X-C chemokines interleukin-8 (IL-8) and GROalpha were dete

81 Production of the C-X-C chemokines interleukin-8 (IL-8) and growth-regulated o

82 Interleukin-8 (IL-8), a C-X-C chemokine, is induced by TNF-alpha and initiates injur

83 TCA3, a C-C chemokine, is produced by Ag-activated T cells and is

84 of the monocyte chemotactic and activating C-C chemokine JE/monocyte chemotactic protein-1 has been p

85 ion at 90 minutes; the generation of the C-X-C chemokine KC (2.86 +/- 0.30 ng/mL at 5 hours); sinusoi

86 this study, we assessed the role of the C-X-C chemokine KC in lung antibacterial host defense using

87 factor alpha and interleukin (IL-12) and C-X-C chemokines KC and macrophage inflammatory protein 2 th

88 Among C-C chemokines known to chemoattract different leukocyte p

89 ytokines with myelogenic potential such as C-C chemokine ligand (CCL)2, interleukin (IL)-6, and VEGF-

90 a, tumor necrosis factor-alpha, IL-6, or C-X-C chemokine ligand 1 in blood or brain, but systemic IL-

91 Crystal structures of M3 in complex with C chemokine ligand 1/lymphotactin and CC chemokine ligan

92 racterize the homologues of human eotaxin (C-C chemokine ligand 11) and CCR3 from other species, such

93 at anti-VEGFR2 therapy up-regulates both C-X-C chemokine ligand 12 (CXCL12) and C-X-C chemokine recep

94 Binding of its ligand, C-X-C chemokine ligand 12 (CXCL12), results in receptor inte

95 4, telomerase reverse transcriptase, and C-X-C chemokine ligand 12 compared with NS-deficient mammary

96 xis requires either of the cognate ligands C-C chemokine ligand 19 (CCL19) or CCL21.

97 identify the T-cell activation regulators C-C chemokine ligand 19 and C-C chemokine receptor 7 as po

98 obesity activates hepatocyte expression of C-C chemokine ligand 2 (CCL2/MCP-1) leading to hepatic rec

99 h) monocytes accrue in response to a brief C-C chemokine ligand 2 burst.

100 s, presumably via a mechanism of decreased C-C chemokine ligand 2 levels in the cerebrospinal fluid.

101 e the role of the C-C chemokine receptor 6/C-C chemokine ligand 20 (CCR6/CCL20) chemokine axis in med

102 n in many inflammatory chemokines, such as C-C chemokine ligand 5, CXC ligand 9 (CXCL9), and CXCL10.

103 F-deficient mice had reduced expression of C-C chemokine ligand 5, CXCL9, and CXCL10 at early time po

104 Protein levels of C-C chemokine ligand-2 (CCL-2)/monocyte chemotactic protei

105 uman CXC chemokine interleukin-8, the murine C chemokine lymphotactin, and the murine CX(3)C chemokin

106 t not TGF-beta2 or TGF-beta3, and elevated C-C chemokines macrophage chemoattractant protein-1, macro

107 The role the C-X-C chemokines macrophage inflammatory protein (MIP)-2 and

108 macrophage inflammatory protein-2 and the C-C chemokines macrophage inflammatory protein-1alpha and

109 ity by induction of the cysteine-cysteine (C-C) chemokine macrophage inflammatory protein 1beta (MIP-

110 on with a decrease in lung levels of the C-X-C chemokine, macrophage inflammatory protein-2 and the C

111 cells may be critical effector cells, and C-C chemokines may play important roles in the initiation

112 Lung mRNA expression of the C-C chemokine MCP-1 was increased in OVA-indomethacin mice

113 ese results suggest that the production of C-C chemokines (MCP-1 or MIP-1 alpha) during an immune res

114 is considerable sequence homology to other C-C chemokines, MCP-2 appears to have unique functional pr

115 functions, has been shown to induce the C-X-C chemokines Mig and IP-10.

116 the receptor for the IFN-gamma-inducible C-X-C chemokines MIG/CXCL9, IP-10/CXCL10, and I-TAC/CXCL11.

117 but had only minor effects on the related C-C chemokines MIP-1 alpha and RANTES.

118 The C-C chemokines MIP-1alpha, MIP-1beta, and RANTES have been

119 Importantly, the C-C chemokines MIP-1alpha, MIP-1beta, and RANTES were resp

120 To elucidate the role of C-C chemokines, MIP-1 alpha and MCP-1, we have used both a

121 The C-C chemokine monocyte chemoattractant protein-1 (MCP-1) i

122 Fractalkine (FKN), a CX(3)C chemokine/mucin hybrid molecule on endothelium, functi

123 Fractalkine is a unique CX(3)C chemokine/mucin hybrid molecule that functions like se

124 Interestingly, the C-X-C chemokine murine macrophage inflammatory protein-2, as

125 age inflammatory protein-2, as well as the C-C chemokines murine monocyte chemoattractant protein-1 a

126 The C-X-C chemokines of the IL-8 family possess potent chemotact

127 CHEMR1 may be a receptor for unidentified C-C chemokine or a low-affinity receptor for MIP-1alpha.

128 cribe cellular and tissue targets of rat C-X-C chemokine peptides.

129 emonstrating that mesothelial cell-derived C-C chemokines play a biologically important role in the r

130 Thus, although C-C chemokines play a broad role in influencing inflammati

131 C-C chemokines play an important role in recruitment of T

132 Lymphotactin (Lptn) is a C chemokine produced predominantly by NK and CD8-positiv

133 -infected epithelial cells suggests that C-X-C chemokines produced by those cells contribute to the m

134 The kinetics of C-X-C chemokine production by C. parvum-infected epithelial

135 We studied the regulation of C-C chemokine production by CD28 costimulatory signals by

136 erived chemokine, MIP-2, and LPS-induced C-X-C chemokine production in the lungs.

137 on; and TNF-alpha, IL-6, and LPS-induced C-X-C chemokine production in the lungs.

138 ncy of resistant cultures without reducing C-C chemokine production.

139 on, and could be neutralized by removal of C-C chemokines (RANTES (regulated upon activation, normal

140 PBM and AM increases the production of the C-C chemokine, RANTES.

141 The three C-C chemokines, RANTES, macrophage-inflammatory protein-1a

142 protein (MCP) 1 are mediated by binding to C-C chemokine receptor (CCR) 2.

143 Here we show that ligation of the C-C chemokine receptor (CCR) 5 can provide a major signal

144 The frequency of homozygous C-C chemokine receptor (CCR) 5- Delta 32 was higher in ES

145 major histocompatibility complex class II, C-C chemokine receptor (CCR) type 1, CCR2, CX3C chemokine

146 chemokine (C-C motif) ligand (CCL)2, CCL4, C-C chemokine receptor (CCR)1, and CCR5, which are involve

147 revealed that HCC-1 specifically activated C-C chemokine receptor (CCR)1, but not closely related rec

148 -) T cells were activated CD69(+)CD45RA(-) C-C chemokine receptor (CCR)7(-) effector memory and perfo

149 s been shown to increase the production of C-C chemokine receptor (CCR5)-binding chemokines under cer

150 The C-C chemokine receptor (CCR7) G protein-coupled receptor i

151 zyme cyclooxygenase-2, the IL-8 receptor C-X-C chemokine receptor (CXCR) 1, and the intracellular kin

152 leukocytes after binding to its receptor C-X-C chemokine receptor (CXCR) 3.

153 The chemokine CXCL16 and its receptor, C-X-C chemokine receptor (CXCR6), affect tumor progression t

154 C-C chemokine receptor 1 (CCR1) is a chemokine receptor th

155 tudy addressed the role of their receptor, C-C chemokine receptor 1 (CCR1), in this model.

156 ME-treated mice expressed higher levels of C-C chemokine receptor 2 (CCR2) and CCR3 mRNA and containe

157 ed with single nucleotide polymorphisms of C-C chemokine receptor 2 (CCR2) gene.

158 C-C chemokine receptor 2 (CCR2) is considered the major G-

159 c steatosis in obese mice deficient in the C-C chemokine receptor 2 (CCR2) that regulates myeloid cel

160 Changes in MCP-1, C-C chemokine receptor 2 (CCR2), procollagen I and III, an

161 enerate mice with a targeted disruption of C-C chemokine receptor 2 (CCR2), the receptor for MCP-1.

162 e inflammation, it remains unclear whether C-C chemokine receptor 2 (CCR2)- and Ly6C-expressing infla

163 C chemokine receptor 5 (CCR5)-Delta 32 and C-C chemokine receptor 2 (CCR2)-64I (relative hazard = 0.4

164 We investigated the role of C-C chemokine receptor 2 (CCR2)-dependent cell recruitment

165 nducible nitric oxide synthase (iNOS), and C-C chemokine receptor 2 (CCR2).

166 osuppressive chemokine, specifically binds C-C chemokine receptor 2 (CCR2).

167 gh) monocytes express heightened levels of C-C chemokine receptor 2 on their surface, avidly infiltra

168 monocyte chemoattractant protein (MCP)-1, C-C chemokine receptor 2(CCR2), interleukin (IL)-1beta, an

169 Compared with MMR- and C-C chemokine receptor 2-deficient mice, significantly hig

170 he human thrombin receptor (PAR-1) and the C-C chemokine receptor 2B.

171 The beta-chemokine receptor C-C chemokine receptor 3 (CCR3) provides a mechanism for t

172 reatment of eosinophils with an mAb to the C-C chemokine receptor 3 (CCR3).

173 The G protein-coupled receptor (GPCR) C-X-C chemokine receptor 3 (CXCR3) is a potential drug targe

174 dition to IL-17A, the chemokine receptor C-X-C chemokine receptor 3 (CXCR3) is also important to enab

175 and abolished their differentiation into C-X-C chemokine receptor 3 (CXCR3)(lo)CD43(lo) effector-like

176 Lymphocytes expressing C-X-C chemokine receptor 3 CD8 significantly correlated with

177 e found that HIV-1 coat proteins that used C-C chemokine receptor 3 or C-X-C chemokine receptor 4 as

178 ig), which like HuIP-10 is an agonist of C-X-C chemokine receptor 3, does not inhibit KSHV-GPCR signa

179 of the chemokine (C-X-C motif) ligand 12/C-X-C chemokine receptor 4 (CXCR4) and VEGF/VEGFR1 pathways

180 r the C-C chemokine receptor 5 (CCR5) or C-X-C chemokine receptor 4 (CXCR4) coreceptor.

181 h C-X-C chemokine ligand 12 (CXCL12) and C-X-C chemokine receptor 4 (CXCR4) in orthotopic murine CRC

182 The G protein-coupled protein receptor C-X-C chemokine receptor 4 (CXCR4) is an attractive target f

183 tors C-C chemokine receptor 7 (CCR7) and C-X-C chemokine receptor 4 (CXCR4) on melanoma cells undergo

184 Internalization of C-X-C chemokine receptor 4 (CXCR4), but not CXCR5, was affec

185 Aggressive human melanomas express, C-X-C chemokine receptor 4 (CXCR4), the receptor for the che

186 ns that used C-C chemokine receptor 3 or C-X-C chemokine receptor 4 as coreceptors inhibited prolifer

187 he stromal cell-derived factor-1 (SDF-1)/C-X-C chemokine receptor 4 axis, in the development of those

188 ifications of the chemokine RANTES bind to C-C chemokine receptor 5 (CCR5) and block human immunodefi

189 We have shown that mice that express the C-C chemokine receptor 5 (CCR5) have enhanced local tumor

190 s study, we demonstrate a crucial role for C-C chemokine receptor 5 (CCR5) in the accelerated recruit

191 used a B16-F10 melanoma model to show that C-C chemokine receptor 5 (CCR5) knockout (CCR5(-/-)) mice

192 we evaluated whether the disruption of the C-C chemokine receptor 5 (CCR5) locus in pigtailed macaque

193 o CD4 followed by engagement of either the C-C chemokine receptor 5 (CCR5) or C-X-C chemokine recepto

194 The C-C chemokine receptor 5 (CCR5) plays a crucial role in fa

195 C-C chemokine receptor 5 (CCR5), a member of G-protein-cou

196 We tested this hypothesis for C-C chemokine receptor 5 (CCR5), a molecule involved in re

197 of breast milk CD4(+) T cells expressed the C chemokine receptor 5 (CCR5), whereas 26%-73% of cells

198 -67% of the vaginal CD4(+) T cells expressed C chemokine receptor 5 (CCR5), whereas 84%-99% coexpress

199 of a protective genotype, consisted of: 1) C-C chemokine receptor 5 (CCR5)-Delta 32 and C-C chemokine

200 es in a G protein-coupled receptor (GPCR), C-C chemokine receptor 5 (CCR5).

201 iral load and could be traced to a single, C-C chemokine receptor 5-tropic founder virus with shorter

202 al autoimmune encephalomyelitis (EAE), the C-C chemokine receptor 6 (CCR6) is critical for pathogenic

203 IL17A, IL17F, retinoid-orphan-receptor C, C-C chemokine receptor 6, and the IL23 receptor.

204 s study was to investigate the role of the C-C chemokine receptor 6/C-C chemokine ligand 20 (CCR6/CCL

205 We hypothesized that chemokine receptors C-C chemokine receptor 7 (CCR7) and C-X-C chemokine recept

206 ells carry out immune functions, using the C-C chemokine receptor 7 (CCR7) and its cognate ligands, C

207 ates CXCR5 but not Bcl6, and downregulates C-C chemokine receptor 7 (CCR7) expression in T cells in v

208 C-C chemokine receptor 7 (CCR7) facilitates entry of T cel

209 ) adipose tissue immune cells that express C-C chemokine receptor 7 (CCR7) in mice and humans, and th

210 The atypical C-X-C chemokine receptor 7 (CXCR7) has been implicated in su

211 ion regulators C-C chemokine ligand 19 and C-C chemokine receptor 7 as potential mediators of immune

212 up-regulation of SDF-1, and its receptor C-X-C chemokine receptor 7, was documented on podocytes and

213 Expression of either human or simian C-C chemokine receptor CCR5 allowed the SIVmac239 envelope

214 The C-C chemokine receptor CCR5 in humans and rhesus macaques

215 The C-C chemokine receptor CCR5 serves an important function i

216 -X-C chemokine receptor type 4 (CXCR4) and C-C chemokine receptor type 1 (CCR1), which are the recept

217 Upstream to Fyn, MCP1 stimulated C-C chemokine receptor type 2 (CCR2) and Gi/o and inhibiti

218 C-C chemokine receptor type 2 (CCR2) and its ligands (CCL2

219 A comparison of the MCP-1/C-C chemokine receptor type 2 (CCR2) chemokine system betw

220 ic burned patients with a special focus on C-C chemokine receptor type 2 (CCR2) expressions on classi

221 C-C chemokine receptor type 2 (CCR2) is expressed by activ

222 whether CCX140-B, a selective inhibitor of C-C chemokine receptor type 2 (CCR2), could further reduce

223 tants of C-C motif chemokine 7 (CCL7) with C-C chemokine receptor type 2 (CCR2), monosulfated CCR2, a

224 The generated MDSC were expressed C-C chemokine receptor type 2 (CCR2), which was enhanced b

225 A C-C chemokine receptor type 2 (CCR2)-positive macrophage s

226 ting factor 1 receptor blockade diminished C-C chemokine receptor type 2 [CCR2(neg) (Ly6C(lo))] monoc

227 macrophage-1 receptor, Sialil-Lewis X, and C-C chemokine receptor type 2 expression in monocytes.

228 especially within the hemoglobin delta and C-C chemokine receptor type 2 genes, respectively, causing

229 The C-C chemokine receptor type 2 protein (CCR2) functions in

230 ngolimod (FTY720)-sensitive manner and use C-C chemokine receptor type 2 to accumulate in inflamed sk

231 encing of the monocyte-recruiting receptor C-C chemokine receptor type 2 with short-interfering RNA d

232 IL-13 receptor alpha1 and donor eosinophil C-C chemokine receptor type 3 (CCR3) and interleukin 1 rec

233 or this activation, and the combination of C-C chemokine receptor type 4 (CCR4) chemokine receptors a

234 tions were impaired by the inhibitors of C-X-C chemokine receptor type 4 (CXCR4) and C-C chemokine re

235 f a proposed molecular mechanism for the C-X-C chemokine receptor type 4 (CXCR4) antagonist 1 (AMD310

236 Moreover, Plg regulated C-X-C chemokine receptor type 4 (CXCR4) expression in stem c

237 aro et al demonstrate high expression of C-X-C chemokine receptor type 4 (CXCR4) mutation in Waldenst

238 The C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role

239 was associated with very high levels of C-X-C chemokine receptor type 4 (CXCR4) production.

240 ly, a pepducin selectively targeting the C-X-C chemokine receptor type 4 (CXCR4) was found to be an a

241 ed by altered expression of the cytokine C-X-C chemokine receptor type 4 (Cxcr4), an established regu

242 The C-X-C chemokine receptor type 4 (CXCR4)/stromal cell derived

243 up-regulation of c-Kit, IL-3Ralpha, and C-X-C chemokine receptor type 4 from either human ECs or emb

244 ing a hybrid beta(2)-adrenergic receptor-C-X-C chemokine receptor type 4 structure as a template, we

245 ce in collagen and elastin staining, and C-X-C chemokine receptor type 4, nuclear factor kappa beta,

246 chrome c, stromal cell-derived factor-1, C-X-C chemokine receptor type 4, vascular endothelial growth

247 studies demonstrated that ORM1 can bind to C-C chemokine receptor type 5 (CCR5) on muscle cells and d

248 cantly higher prechallenge levels of CD4(+)C-C chemokine receptor type 5 (CCR5)(+)HLA-DR(+) T cells i

249 on of the TFH program, as exemplified by C-X-C chemokine receptor type 5 (CXCR5) upregulation.

250 get T-cell population is enriched with a C-X-C chemokine receptor type 5 (CXCR5)(+)CD4(+) TFH precurs

251 Individuals homozygous for the C-C chemokine receptor type 5 gene with 32-bp deletions (C

252 ms targeting the human hemoglobin beta and C-C chemokine receptor type 5 genes have substantial off-t

253 emokine (C-C motif) ligand 5 that binds to C-C chemokine receptor type 5 on BCCs and BCCs secrete cyt

254 While frequencies of foreskin C-C chemokine receptor type 5(+) (CCR5(+)) T cells, T regu

255 SIV)-specific CD8 T cells express CXCR5 (C-X-C chemokine receptor type 5, a chemokine receptor requir

256 ied zinc finger nucleases (ZFNs) targeting C-C chemokine receptor type 5.

257 motif) ligand 16 (CXCL16) that binds to C-X-C chemokine receptor type 6 (CXCR6) on MSCs and MSCs sec

258 ion and expression of the migration marker C-C chemokine receptor type 7 (CCR7) in PGN-stimulated cel

259 e-homing molecules CD62 ligand (CD62L) and C-C chemokine receptor type 7 (CCR7), which are expressed

260 ling (CD14dimCD16(+)) monocytes, and their C-C chemokine receptor type-2 (CCR2) expression were quant

261 The C-C chemokine receptor, CCR2, has been identified as the p

262 One C-C chemokine receptor, CCR2, has been identified that med

263 emotaxis is mediated primarily through the C-C chemokine receptor, CCR3.

264 The C-C chemokine receptor-1 (CKR-1), the MCP-1 receptor-A (MC

265 Ccl-2; also known as MCP-1) or its cognate C-C chemokine receptor-2 (Ccr-2) develop cardinal features

266 n immunodeficiency virus (HIV) and human C-X-C chemokine receptor-4 (CXCR4) facilitates migration of

267 antly, expression of the protumorigenic, C-X-C chemokine receptor-4 (CXCR4), was reduced in DEN-induc

268 lpha) receptor gene Scya3r and two related C-C chemokine receptor-like genes reside.

269 ed ApoE-/-OPN-/- mice expressed less CD68, C-C-chemokine receptor 2, and VCAM-1.

270 HIV-1 strains use C-C-chemokine receptor 5, CCR5, as a coreceptor for host t

271 ) joint, we investigated the expression of C-C chemokine receptors (CCR) 1-6 and C-X-C receptor 3 (CX

272 Fibronectin, C-C chemokine receptors (CCRs)2 and 7, and oxidative stres

273 filtrate by modulating the expression of C-X-C chemokine receptors 2 and 4 on peripheral blood neutro

274 n experiments using cells transfected with C-C chemokine receptors, 125I-MCP-2 bound to human embryon

275 interferon-gamma, [IFN-gamma], and IL-12), C-C chemokines (regulated upon activation, normal T cell e

276 C-X-C chemokine secretion in C. parvum-infected epithelial c

277 -gamma-inducible protein 10 (HuIP-10), a C-X-C chemokine, specifically inhibits signaling of KSHV-GPC

278 eceptor has been shown to respond to the C-X-C chemokine stromal-derived factor (SDF-1) and has recen

279 Lymphotactin, the unique member of the "C" chemokine subclass, is a highly basic protein that bi

280 e-receptor complexes across the CC, CXC, and C chemokine subfamilies.

281 otactic protein (MCP)-2 is a member of the C-C chemokine subfamily, which shares more than 60% sequen

282 tional properties in comparison with other C-C chemokines such as MCP-1 and MCP-3.

283 Levels of C-C chemokines such as monocyte chemoattractant protein-1

284 aracterization of a novel murine and human C-C chemokine termed Exodus-2 for its similarity to Exodus

285 4) is an abundant platelet alpha-granule C-X-C chemokine that has weak chemotactic potency but strong

286 C-C chemokine (HCC)-1 is a recently cloned C-C chemokine that is structurally similar to macrophage i

287 eptide-2 (NAP-2) are two closely related C-X-C chemokines that differ in their abilities to induce ch

288 moattractant protein-1 is one of the major C-C chemokines that has been implicated in liver injury.

289 t MCP-2 may share the receptors with these C-C chemokines, the actual functional receptors for MCP-2

290 yte chemoattractant protein-1 (MCP-1) is a C-C chemokine thought to play a major role in recruiting m

291 In this study, the ability of several C-C chemokines to induce transendothelial migration (TEM)

292 ral basis for pleiotropic signaling of the C-C chemokine type 5 (CCR5) G protein-coupled receptor (GP

293 ion of proinflammatory cytokines C-C and C-X-C chemokines was seen in the rats exhibiting necroinflam

294 ograft RNA expression of several C-X-C and C-C chemokines was tested during rejection of full thickne

295 e in eotaxin, a potent eosinophil-specific C-C chemokine, was also observed during fibroblast-mast ce

296 When the two C-C chemokines were individually co-incubated with Con-A-s

297 experiments provide direct evidence that C-X-C chemokines, when expressed in sufficient quantity in t

298 and cloning of a cDNA that encodes a mouse C-C chemokine with 68% amino acid identity to guinea pig E

299 nflammatory protein 1alpha (MIP-1alpha), a C-C chemokine with monocyte chemoattractant capability, in

300 ic protein-4 (MCP-4) is a newly identified C-C chemokine with potent eosinophil chemoattractant prope