ライフサイエンスコーパス: C terminus

1 he transactivation domain (TAD) of the BMAL1 C terminus.

2 n of as few as seven amino acids from the K2 C terminus.

3 and fusing an interacting BH3 peptide to the C terminus.

4 ent with faster reverse protonation from the C terminus.

5 tion on Ser-1700 and Ser-1928 at the channel C terminus.

6 ic clash between the D1-domain and ataxin3's C terminus.

7 uction of a peptide derived from the SNAP-25 C terminus.

8 524E disrupt the regulatory role of the Cox1 C terminus.

9 TEMIS is regulated via autoinhibition by its C terminus.

10 acid activation domain (AD) within the Rap1 C terminus.

11 1-bp frameshift and generate a novel protein C terminus.

12 bition of the catalytic subunit (CNA) by its C terminus.

13 nus, in helix 1 (residues 14-24), and at the C terminus.

14 ange only in the final 20 amino acids of the C terminus.

15 ), the penultimate amino acid residue at the C terminus.

16 olves threading of the rubisco large subunit C terminus.

17 at it bears a 19-amino acid extension at the C terminus.

18 ent with faster forward deprotonation to the C terminus.

19 Arg-1336, a location relatively close to its C terminus.

20 the N terminus and a Gly-rich domain at the C terminus.

21 the rod domain, rather than ABS3 at the far C terminus.

22 ugh a novel dynein interacting site near its C terminus.

23 stop codon with 46 additional codons at the C-terminus.

24 proteins that interact with the CB1R at the C-terminus.

25 s isomerization of a single proline near the C-terminus.

26 ange in only the final 20 amino acids of the C-terminus.

27 t of pleiotrophin located near the protein's C-terminus.

28 N-terminus, the central salt bridge, and the C-terminus.

29 ts evolutionary conserved TDU2 domain at its C-terminus.

30 ects carrying a frameshift deletion in DISC1 C-terminus.

31 o areas around the hydrophobic patch and the C-terminus.

32 the archaea and that has a PIP motif at its C-terminus.

33 lently linking the domains, and the proximal C-terminus.

34 an anti-autoinhibitor domain at the extreme C-terminus.

35 ted between the glutamate-binding domain and C-terminus.

36 orylation of key serine residues in the IRF6 C-terminus.

37 f different charge and length at the protein C-terminus.

38 quires only the two cysteines closest to the C-terminus.

39 horylation at threonine-468 of a CB1R distal C-terminus 14-mer peptide reduced CB1R-CRIP1a associatio

40 ith the N-terminus (1-60 aa) of KLF4 via its C-terminus (228-355 aa) and directly targets KLF4 for ub

41 how the charge and length variations of the C-terminus affect the aggregation propensity of alpha-sy

42 single amino acid in the distal part of the C-terminus affects multiple aspects of NHE3 complex form

43 n at both its N-terminal core domain and the C-terminus alpha6 helix through two parallel ubiquitin-d

44 The N- to C-terminus amide cyclized peptide with one d-amino acid

45 It contains a helicase core domain in its C terminus and a potential KH domain in its N terminus.

46 t patients impaired the interaction with the C terminus and also affected protein stability.

47 lyzed several variants located in the GluN2B C terminus and found that three variants in patients wit

48 n conduction only from the N terminus to the C terminus and prevents reverse current under low intern

49 e-like CRY circadian regulation on the BMAL1 C terminus and the CLK PAS-B domain and demonstrate the

50 nal region (amino acids 586-660) of the NHE3 C terminus and to the NHE3 C-terminal four amino acids.

51 serine-threonine clusters in the receptor's C terminus and two conserved phosphate-binding lysines i

52 plex with peptides corresponding to the RPN2 C terminus and ubiquitin.

53 This interaction is mediated by the Dbf4 C terminus and was successfully reconstituted in vitro.

54 a single positive charge from the lysine at C-terminus and causes aggregation of citrate anion-stabi

55 Casein kinase 2 (CK2) binds to the NHE3 C-terminus and constitutively phosphorylates a downstrea

56 sistent with an interaction between the Art1 C-terminus and the Mup1 acidic patch.

57 including unfolding initiated at the tagged C-terminus and translocation via a power stroke mechanis

58 nation of helices I-V from ChR1, without its C-terminus, and helices VI-VII from ChR2, is used as a t

59 s of fluorescent proteins to alpha-synuclein C-terminus are often used in cellular and animal studies

60 Expression of the K2 C terminus as an extension of membrane-anchored P-select

61 through a yeast two-hybrid assay using NKCC2 C terminus as bait.

62 (> 6) and to reduced polarity around the TM3 C terminus as confirmed by fluorescence spectroscopy.

63 interactions with the CaV2.1 alpha1 subunit C-terminus at the active zone, the role of these interac

64 Two amphipathic helices within the Naa60 C terminus bind the membrane directly in a parallel posi

65 This C-terminus binds to the Groucho/TLE co-repressor, and al

66 The helix at the C-terminus binds to the well-known p53-binding pocket in

67 RS-CoV S protein fused to the RABV G protein C terminus (BNSP333-S1).

68 dynamics is observed, decreasing from N- to C-terminus, both in the presence and absence of TFE.

69 ll bind to K2 and displace the endogenous K2 C terminus but may not restore the conformation needed f

70 However, the humoral response to the PfCSP C terminus (C-PfCSP) is less well characterized.

71 inimal syntaxin 1A-binding sequence of Kv2.1 C terminus (C1aB) was first identified via a far-Western

72 The IFT46 C-terminus can assemble into and stabilize IFT-B but doe

73 missense mutations, mainly localized at the C terminus, cause dominant distal arthrogryposis 3 (DA3)

74 the catalytic cysteine 12 A closer to the Ub C terminus compared with previous Uba1 structures.

75 tein CAR-DCN was engineered with an extended C-terminus comprised of CAR homing peptide that recogniz

76 ted between the conserved domains and at the C terminus, contain sites for phosphorylation by multipl

77 verexpressed, and identified a region in the C terminus containing a putative amphipathic helix (APH)

78 ion of two acidic sequences within the MRE11 C terminus containing serines 558/561 and 688/689.

79 The C terminus contains two regulatory domains, the autoinhi

80 of kinesin-1 directly interacts with the APC C-terminus, contributing to the peripheral localisation

81 Peptides mimicking the CB1R C-terminus could bind to both CRIP1a in cell extracts as

82 The proximal Kv7.1 C terminus (CT) binds calmodulin (CaM) and phosphatidyli

83 aphanous-autoregulatory domain (DAD) and the C terminus (CT) of formins have also been shown to regul

84 These mutations, as well as C terminus deletion (Cox1DeltaC15), reduced binding of M

85 y) to characterize the binding of two Sema3A C-terminus-derived basic peptides (FS2 and NFS3) to hepa

86 Deletion of the K2 C terminus did not affect its binding to the integrin be

87 on of the last 10 amino acids from the pUL33 C terminus did not affect viral replication or the inter

88 e-splicing variant missing 90 amino acids at C-terminus does not promote LD fusion or TAG accumulatio

89 eraction between the channel's intracellular C-terminus domain and the SNARE (soluble N-ethylmaleimid

90 al change of the GluN1 subunit intracellular C-terminus domain.

91 lgs) and human BCL9 and B9L to show that the C-terminus downstream of their adaptor elements is cruci

92 t and hydrophobic spacer peptide (SP) at its C-terminus early in the maturation process, which is pro

93 levels of EIN2 protein and demonstrate EIN2 C terminus (EIN2-C) is sufficient to rescue the levels o

94 The C terminus encompassing the nuclear localization signal

95 364 and distal sequences located at the ICP0 C terminus enhance the degradation of PML II.

96 ) exists as a transmembrane isoform with the C-terminus facing the mitochondrial matrix and the N-ter

97 1 (K1) exhibited a similar dependence on its C terminus for integrin activation.

98 d configuration, the last 36 residues at the C-terminus form a bundle of five alpha-helices co-linear

99 In particular, the C terminus functions as a toggle switch, which affects a

100 result is consistent with the view that the C-terminus functions as a molecular sieve and stabilizer

101 fused GCSF with the Fc domain of IgG1 at the C terminus (GCSF-Fc) and with the maltose binding protei

102 6+ and its adaptor GAIP interacting protein, C terminus (GIPC) accumulate at the tips of these filopo

103 residues either at the N-terminus (BMP2) or C-terminus (HA).

104 thereby restricting it to homologous to E6AP C-terminus (HECT) and RING-in-between-RING (RBR) E3s.

105 and by the aS deletion mutant that lacks the C-terminus, i.e., aS (1-99).

106 Hyperphosphorylation of this serine in cTnI C terminus impacts heart function by depressing diastoli

107 ndings highlight the importance of the CROPs C terminus in cell-surface binding and a role for neutra

108 full-length approximately 7-kDa cytoplasmic C terminus in cultured cells and purified from Escherich

109 We present crystal structures of the eVP30 C-terminus in complex with this eNP peptide.

110 when AR retains LBD suggesting a role for AR C-terminus in E2/E3 substrate recognition.

111 out the role of dimerization and that of the C-terminus in the complete maturation of fibrillar aS.

112 Monarch mutants lacking the BMAL1 C terminus including the TAD exhibited arrhythmic eclosi

113 that bind throughout the NHE3 intracellular C-terminus, including calcineurin homologous protein, th

114 nhibition of a second Cdc20 through the Mad3 C terminus, independent of Mad2 binding to this Cdc20 mo

115 FLASH through its distant C terminus independently interacts with the C-terminal S

116 ecombinant domain 1, 1+2 (N terminus), or 4 (C terminus) independently activated myofibroblast differ

117 Thus in SMCs, the beta-catenin C-terminus indirectly represses p53, and this function i

118 eshold of positive charge in the mutant CALR C terminus influences both binding of mutant CALR to MPL

119 modified INT: 15-amino acid deletion at the C terminus (INTDeltaC15) and histidine substituted at th

120 Here we show that ParP's C-terminus integrates into the core-unit of signaling ar

121 Specifically, the TFG C terminus interacts with Sec23 through a shared interfa

122 tions, L290S and A296V, converting the FHR-1 C terminus into that of factor H (FH).

123 The ARTEMIS C terminus is dispensable for cellular V(D)J recombinati

124 Our results reveal that POT1 C terminus is essential to prevent initiation of genome

125 ocalized intracellularly, and only the short C terminus is extracellular (N cyt/C exo topology).

126 tive electrostatic charge of the mutant CALR C terminus is required for mutant CALR-mediated activati

127 omain is essential in both cases whereas the C terminus is required for recruitment via BCR stimulati

128 Moreover, we show that adding a tag to the C-terminus is detrimental to KCC2 function.

129 is that tyrosine (Y382-384) within the P2X7R C-terminus is differentially modulated by repeated morph

130 how that under physiological conditions, the C-terminus is indeed an alpha-helical bundle, located ne

131 lity during aggregation, and the hydrophobic C-terminus is involved to an intermediate extent.

132 r data suggest that polymorphism in the CagA C-terminus is responsible for differential alterations i

133 A polybasic region at the Rga6 C-terminus is responsible for its membrane localization.

134 x43 has a 20 kDa internally translated small C terminus isoform, GJA1-20k (Gap Junction Protein Alpha

135 n of 1 provided several analogs, including a C-terminus-linked coumarin derivative (22) that exhibite

136 leased to bind to the carrier domain via its C-terminus, locking the carrier in an inhibited state.

137 segment disk and suggests that the protein's C terminus may modulate membrane curvature-generating ac

138 an amidated arginine-phenylalanine (RFamide) C-terminus motif.

139 In both states, the ArfA C-terminus occupies the mRNA tunnel downstream of the A

140 Peptide attachment to the C terminus of 14-3-3 via an optimal linker allows its ph

141 consisting of three amino acids (IDL) to the C terminus of a fusion inhibitor to fit this new target.

142 oid group is attached to a cysteine near the C terminus of a substrate protein by protein farnesyltra

143 e extending from the catalytic domain in the C terminus of A3G to its N terminus.

144 hia coli A 12-amino acid-long peptide at the C terminus of AaRS serves as a specific localization seq

145 is ectopically expressing only exon 4 of the C terminus of AcMFT and FT.

146 de that bind fibrinogen, is conserved at the C terminus of all Coa molecules, but its functional sign

147 x that interacts with the negatively charged C terminus of alpha-Syn.

148 enH3 nucleosome binding CENPC-k motif at the C terminus of Arabidopsis thaliana KNL2, which is conser

149 Similar peptides, for example, from the C terminus of beta-actin or NLSIII of the p53 protein, s

150 Therefore, these results indicate that the C terminus of CCHFV NSs triggers mitochondrial membrane

151 When we replace the C terminus of CCR5 with the C terminus of CXCR4, R5 viru

152 ter the addition of IDL (Ile-Asp-Leu) to the C terminus of CHR peptide WQ or MT-WQ, the conjugated pe

153 n we replace the C terminus of CCR5 with the C terminus of CXCR4, R5 viruses become more susceptible

154 Interestingly, the C terminus of DOG1 is either absent or not conserved in

155 The C terminus of either the Galphas or Galphaq subunit is s

156 mino acid exchanges N456A+S457A+E458Q in the C terminus of full-length ARTEMIS resulted in unmasking

157 itic spine morphology and interacts with the C terminus of GABAB receptors (GABABRs) to control their

158 A highly conserved threonine near the C terminus of gp120 of human immunodeficiency virus (HIV

159 nd to an 11-residue peptide derived from the C terminus of HPV16 E6), were obtained.

160 Our findings indicate that the extreme C terminus of K2 is essential for integrin co-activation

161 d a 14-3-3 mode III binding site at the very C terminus of KAT1 and cocrystallized it with tobacco (N

162 at PA specifically and directly binds to the C terminus of KIF5B.

163 lectrophoretic mobility shift assay that the C terminus of KNL2 binds DNA sequence-independently and

164 e mediated by the binding of the cytoplasmic C terminus of Kv3.3 to Hax-1, an anti-apoptotic protein

165 dies indicate that the 22 amino acids at the C terminus of Loqs-PD, including an FDF-like motif, dire

166 Mtalpha(514-549), which is accessible at the C terminus of mycobacterial subunit alpha, is a promisin

167 tification of the 3Cpro cleavage site at the C terminus of N supported previous observations that PED

168 wo novel native phosphorylation sites in the C terminus of NaV1.5 that impair FGF13-dependent regulat

169 firmed this interaction and mapped it to the C terminus of NS5A of both genotype 1 and 2.

170 e complementation analyses revealed that the C terminus of OeGLU is essential for the proper assembly

171 rictly conserved arginine residue toward the C terminus of ORF52 play critical roles in its ability t

172 metric analysis, it is demonstrated that the C terminus of P10 is phosphorylated during virus infecti

173 along with a modified HA epitope tag in the C terminus of PB1 resulted in influenza A viruses (IAV)

174 acid mutations and a modified HA tag at the C terminus of PB1, which is sufficient to attenuate the

175 In the final transmembrane state, the C terminus of pHLIP gets exposed to the cytoplasm of the

176 icate that the membrane translocation of the C terminus of pHLIP, the folding step more directly rele

177 currently known SIM are both located at the C terminus of PIASy, and both are required for the full

178 ates the attachment of the GPI anchor to the C terminus of precursor proteins in the endoplasmic reti

179 Additionally, our results identify the C terminus of PrP(C) as a new and potentially more drugg

180 turn, that conformational differences in the C terminus of PrP(Sc) also contribute to the phenotypic

181 e identify a polybasic motif in the proximal C terminus of retigabine-sensitive KCNQ channels that co

182 rrestin complex, in which the phosphorylated C terminus of rhodopsin forms an extended intermolecular

183 o main, previously undetected, features: the C terminus of Rpn3 protrudes into the mouth of the ATPas

184 The C terminus of Shank3 contains a sterile alpha motif (SAM

185 The data suggest that the C terminus of SPI-1 acts as a competitive inhibitor of t

186 he last four amino acids at the newly formed C terminus of SPI-1 matched both the cleavage specificit

187 We propose a model where the C terminus of TF modulates the palmitoylation of TF at t

188 maintain topological integrity of the labile C terminus of the alpha subunit (site A).

189 between intracellular loops 2 and 3 and the C terminus of the beta2AR with the GRK5 RH bundle subdom

190 nases regulated by an autoregulatory segment C terminus of the catalytic core that blocks myosin regu

191 very similar to that of the tetramer but the C terminus of the dimer is more flexible.

192 the cyclic nucleotide-binding domain and the C terminus of the HCN channel are critical for conferrin

193 immediately digested 6 amino acids from the C terminus of the longer subunit of TSLP to generate a s

194 ommon posttranslational modifications at the C terminus of the peptide in vivo to create the pathogen

195 2) installation of a clickable group at the C terminus of the recombinant protein/peptide with almos

196 rate-sensing hinge that recognizes the bound C terminus of the substrate.

197 osed state by a hydrogen bond network at the C terminus of the THBs, which is lost when the pores ass

198 o five alanine residues near either the N or C terminus of the transmembrane domain (TMD) likely prom

199 The interface residues at the C terminus of transmembrane beta-barrels form the beta-s

200 to dynamic dissociation of NHERF1/2 from the C terminus of TRPC5 as a prerequisite for DAG sensitivit

201 A2B and MMS19 physically interacted with the C terminus of viperin and used CIA1 as the primary viper

202 eviously in picornaviruses is present at the C terminus of VP1, a position where integrin binding mot

203 A short sequence of amino acids at the C terminus of ZFP809, including a single lysine residue

204 alpha1 but does not affect structure at the C-terminus of alpha2.

205 ve peptides and proteins specifically at the C-terminus of aspartic acid and at the N-terminus of cys

206 We propose a model in which the C-terminus of ATP8A2 consists of an autoinhibitor domain

207 We investigated the role of the C-terminus of ATP8A2 in its expression, subcellular loca

208 ans of immunization with NtCFlg fused to the C-terminus of Bet v 1 inhibited binding of patients' IgE

209 (NtCFlg) was genetically fused to the N- or C-terminus of Bet v 1.

210 oreover, we identify a minimal region in the C-terminus of Cac1, including the structured winged heli

211 Fusing GFP onto the C-terminus of CbiK(P) confirmed that the protein is tran

212 dominant-negative frameshift mutation at the C-terminus of choline transporter that was associated wi

213 hat substitutions at both the N-terminus and C-terminus of Cl-amidine result in >100-fold increases i

214 The C-terminus of CSB and, in particular, its ubiquitin-bind

215 ly conserved FLV motif was identified in the C-terminus of DLP1, mutation of which significantly redu

216 , we examined the structural dynamics of the C-terminus of EcMscL using site-directed spin labelling

217 Further, the Endocarpon-specific C-terminus of EpMBF1 was found to participate in stress

218 easome degradation, and fusion of GFP to the C-terminus of hClC-Kb improves protein expression.

219 C-terminus of Hsc/p70-Interacting Protein (CHIP) is a ho

220 ggests that the key binding partners are the C-terminus of LtnA1 and pyrophosphate of lipid II.

221 de of alpha1(I) collagen (Trimer-Tag) to the C-terminus of mature human TRAIL leads to a disulfide bo

222 Here we show that the far C-terminus of MCAK plays a critical role in regulating M

223 t has extensive sequence similarity with the C-terminus of myospryn.

224 via a recently identified LEWD domain in the C-terminus of nesprin-1.

225 omain that interacts with the phosphorylated C-terminus of Pol II (CTD-interacting domain, CID).

226 d or green fluorescent proteins to the N- or C-terminus of PR, respectively.

227 Mutations near the N-terminus and C-terminus of PZase were associated with East-Asian and

228 glycine and an added GGGGSLPETGG peptide at C-terminus of SCRII, SCRII subunits were conjugated by s

229 show that a unique, conserved domain at the C-terminus of Swc5, called Bucentaur (BCNT), is essentia

230 s believed to be mediated by both the N- and C-terminus of TDP-43; however, the mechanistic basis of

231 We show that C-terminus of the CAV1 P158 protein contains a functiona

232 on of green fluorescent protein (GFP) to the C-terminus of the channel may ameliorate proteasome degr

233 significance of the interaction between the C-terminus of the Dscams and multi-PDZ domain-containing

234 c gold finger peptides were derived from the C-terminus of the HIV nucleocapsid p7 protein (NCp7-F2)

235 nisin with lipid II at the pyrophosphate and C-terminus of the pentapeptide chain.

236 es that result in coiling of the hydrophobic C-terminus of the peptide on or near the droplet surface

237 n is observed around a reverse turn near the C-terminus of the protein.

238 xin-I inhibits release by inserting into the C-terminus of the SNARE complex.

239 und to a truncated SNARE complex lacking the C-terminus of the synaptobrevin SNARE motif (SNAREDelta6

240 variants (R8272Q, S8381C and N8406K) in the C-terminus of the SYNE1 gene (nesprin-1) were identified

241 ulin with a calmodulin-binding domain in the C-terminus of TRPA1.

242 e stimulatory while its transposition to the C-terminus of TSPY results in an inhibitory hybrid prote

243 and plays a critical role in activating the C-terminus of ubiquitin or UBL, which is an essential st

244 y, deletion of the Par3-binding motif at the C-terminus of VE-cadherin impairs apicobasal polarity an

245 minantly in zinc fingers (ZF) 2 and 3 at the C-terminus of WT1, which together with ZF4 determine the

246 four additional Cys residues in TF's unique C terminus, or all nine Cys residues in TF.

247 Mutations within the p12 C terminus (p12 PM13 to PM15) block early stages in vira

248 ent alpha-helix (within the purified soluble C terminus) partitioned into membranes only when its aci

249 transmembrane segments and the intracellular C-terminus (PC1-5TMC) down-regulate the phosphorylation

250 In addition, mice expressing the C terminus phosphonull in ipRGCs reentrain faster to a d

251 acking all C-terminal phosphorylation sites (C terminus phosphonull) leads to a prolonged intrinsic l

252 trate that both the charge and length of the C-terminus play an important role at the stage of initia

253 ite the evidence that the negatively charged C-terminus plays a critical role in the regulation of al

254 We conclude that the C-terminus plays an important role in the efficient fold

255 These peptides were extended at the C terminus (POmega) and contained charged amino acids no

256 erence for small hydrophobic residues at the C terminus (POmega).

257 The POT1 C-terminus (POT1C) forms a bilobal structure consisting

258 e Arg/N-end rule pathway, which recognized a C terminus-proximal degron of Chk1.

259 egrees for JM22 and by a focus by F50 on the C terminus rather than the center of the MHC alpha1 heli

260 ported that the last 15 residues of the Cox1 C terminus regulate Cox1 synthesis by modulating an inte

261 el mechanism by which phosphorylation at the C terminus regulates calcium signaling by tuning the con

262 es, mostly based on their long intracellular C terminus regulating trafficking to the cell membrane,

263 ered that adding fluorescent proteins to the C-terminus resulted in constitutive anion channel activi

264 Moreover, dissection of the C terminus revealed that palmitoylation was not sufficie

265 hosphorylation at four sites within the AQP2 C terminus (Ser(256), Ser(261), Ser(264), and Thr(269)),

266 ternative 3'-end processing, whose divergent C terminus shares the CBD common to all isoforms, but la

267 Meanwhile, charge variation of the C-terminus significantly changed the rate of alpha-synuc

268 ng the channel gating, while the rest of the C-terminus stays assembled.

269 We observed that the last 18 residues of the C terminus ("tail" region) of IN (residues 1-286) determ

270 eucine motif housed in the cytoplasmic Slack C terminus that binds AP-2.

271 amino-acid-long target sequence at the UL128 C terminus that binds the 13B5 antibody with an affinity

272 accumulation of NOTCH2 carrying a truncated C terminus that escapes FBW7-mediated ubiquitination and

273 We identify a conserved region in the Ulp2 C terminus that mediates its specificity for rDNA-associ

274 ved nuclear localization signal (NLS) at its C-terminus that binds to importin-beta and is required f

275 carries a polyglutamine stretch close to the C-terminus that triggers a neurodegenerative disease in

276 In addition to the Orai C terminus, the main coupling site for STIM1, the Orai N

277 main through a 37-residue domain and the HCN C terminus through the TPR domains.

278 o a natural minimal cytochrome domain in its c-terminus to achieve direct electron transfer.

279 ntly depleted of H3K27Ac, thus DUX4 uses its C-terminus to induce a global reorganization of H3K27 ac

280 es a rearrangement that apposes the BCL9/B9L C-terminus to TCF.

281 arcade gene cluster, binds tightly with its C-terminus to the hydrophobic groove of crenactin.

282 a its N terminus binds to STING and, via its C terminus, to TBK1.

283 slocated to the plasma membrane, whereas the C-terminus truncated (DeltaC) form localized in the cyto

284 at selective expression of dominant-negative C-terminus-truncated human DISC1 (mutant DISC1) in astro

285 This dependence on the C terminus was also observed in activation of endogenous

286 A peptide corresponding to the C terminus was unstructured in solution and only folded

287 alpha2, likely its 80-kDa fragment from the C terminus, was found to be transported across the semin

288 t, peptides containing tyrosine in the N- or C-terminus, were rapidly oxidized forming multimer units

289 Abeta42 and Abeta40 differ only near the C-terminus, where curcumin interacts, while Zn(2+) inter

290 erved sortase A-dependent cell wall-anchored C terminus, whereas the surface-exposed N terminus is hi

291 a conserved threonine in the cytosolic AMT1 C terminus, which allosterically inactivates AMT1 trimer

292 ns a unique 29-amino acid insertion near the C terminus, which folds as a separate domain in the stru

293 ice and one in the R peptide at the envelope C terminus, which is removed during virus assembly.

294 aches to lipid cargoes via a PX motif at its C-terminus, which has nanomolar affinity for bilayers co

295 of S3, the S4-S5 interdomain linker, and the C-terminus, which is associated with regulation of openi

296 nserved Ser/Thr cluster in the more proximal C-terminus, which was responsible for the beta-arrestin-

297 DAT inhibitors, whereas substituting the DAT C terminus with that of SERT affected neither substrate

298 agate from the N terminus all the way to the C terminus, without destabilizing the dimeric state.

299 zing label or placement of the labels at the C terminus would further improve the targeting propertie

300 Placement of a label at the C terminus yields the best biodistribution features for