ライフサイエンスコーパス: C-kinase

1 fied protein, RACK-1 (receptor for activated C kinase).

2 collectively RACKs (receptors for activated C-kinase).

3 teins, STICKs (substrates that interact with C-kinase).

4 zyme-specific RACKs (receptors for activated C-kinase).

5 tively called RACKs (Receptors for Activated C-Kinases).

6 h Hesperadin, a potent inhibitor of Aurora B/C kinases.

7 Protein Interacting with C Kinase 1 (PICK1) is a Bin/Amphiphysin/Rvs (BAR) domain

8 Protein interacting with C kinase 1 (PICK1) is a PDZ and BAR domain-containing pr

9 Protein interacting with C kinase 1 (PICK1) is an AMPAR-binding protein shown to

10 ) domain-containing protein interacting with C kinase 1 (PICK1), because MF-PYR synapses in young PIC

11 protein (GRIP) and protein interacting with C kinase 1 (PICK1)-regulate the availability of AMPARs f

12 protein (ABP), and protein interacting with C kinase 1 (PICK1).

13 Z domain-containing protein interacting with C kinase 1 (PICK1).

14 Caenorhabditis elegans Receptor of Activated C Kinase 1 (RACK-1) is required for cytokinesis, germlin

15 f these proteins, the receptor for activated C kinase 1 (RACK1) and the dynein intermediate chain, co

16 p-regulated levels of receptor for activated C kinase 1 (RACK1) and the intermediate filament protein

17 In this pathway, receptor for activated C kinase 1 (RACK1) functions as a novel scaffold that bi

18 The receptor for activated C kinase 1 (RACK1) is a conserved scaffold protein that

19 Receptor for activated C kinase 1 (RACK1) is a multifunctional, WD motif-contai

20 ere, we show that the receptor for activated C kinase 1 (RACK1) is a novel pVHL-interacting protein.

21 demonstrate that the receptor for activated C kinase 1 (RACK1) serves as an adaptor for PKC-mediated

22 re we report that the receptor for activated C kinase 1 (RACK1), a novel binding protein of heterotri

23 Receptor for Activated C Kinase 1 (RACK1), a novel G betagamma-interacting prot

24 agamma interacts with Receptor for Activated C Kinase 1 (RACK1), a protein that not only binds activa

25 -3 interacts with the receptor for activated-C kinase 1 (RACK1), a scaffold protein that folds into a

26 us interacts with the receptor for activated C kinase 1 (RACK1), a scaffolding/anchoring protein impl

27 , including PKCdelta, receptor for activated C kinase 1 (RACK1), and p21.

28 ytosis, viz., receptor for activated protein C kinase 1 (RACK1), muscle integrin binding protein (MIB

29 r/scaffolding protein receptor for activated C kinase 1 (RACK1), which was previously reported to int

30 amma), as well as the receptor for activated C kinase 1 (RACK1).

31 orm is sequestered by receptor for activated C kinase 1 (RACK1).

32 hat links P0 with the receptor for activated C kinase 1 (RACK1).

33 ding protein PICK1 (protein interacting with C kinase 1) contains an N-terminal PSD-95/Discs large/ZO

34 suppressor, PICK1 (Protein interacting with C kinase 1), is a transport protein that regulates the t

35 atases, PP1 and PP2A, receptor for activated C kinase 1, and actin.

36 : Increases in c-src, receptor for activated C kinase 1, calreticulin, and caspase 3 and decreases in

37 rectly binds to the protein interacting with C-kinase 1 (PICK1) and forms a complex with alpha-amino-

38 The protein interacting with C-kinase 1 (PICK1) directly interacts with GluA2/3 subun

39 Here we show that protein interacting with C-kinase 1 (PICK1) is a downstream effector of GTP-bound

40 We show that protein interacting with C-kinase 1 (PICK1) recruits activated protein kinase Cal

41 nteraction with the protein interacting with C-kinase 1 (PICK1) to regulate NMDA receptor (NMDAR)-ind

42 rasynaptic sites by protein interacting with C-kinase 1 (PICK1), because disrupting GluR2/PICK1 inter

43 Here, we show that receptor for activated C-kinase 1 (Rack1) can bind with c-Jun and ubiquitin lig

44 e scaffold protein RACK1 (receptor activated C-kinase 1, GNB2L1) as a novel ATG5 interactor and an au

45 pha with PKC scaffold receptor for activated C-kinase 1.

46 lated in neurons by protein interacting with C kinase-1 (PICK1) and protein kinase C (PKC), and show

47 Receptor for activated C kinase-1 (RACK1) and protein kinase C-alpha (PKCalpha)

48 The receptor for activated C kinase-1 was also found to associate with the spectrin

49 beta, PKC theta, and receptor for activated C kinase-1) cotranslocate to the uropod.

50 es implicate PICK1 (protein interacting with C kinase-1) in activity-dependent internalization of Glu

51 th respect to RACK-1 (receptor for activated C kinase-1), an adaptor protein that has been proposed t

52 s 1) protein PICK1 (protein interacting with C kinase-1).

53 protein or ABP) and protein interacting with C-kinase-1 (PICK) regulate subunit trafficking and plast

54 n (GRIP)/(ABP), and protein interacting with C-kinase-1 (PICK1) that interact with the GluR2 subunit

55 e PDZ domain of the protein interacting with C-kinase-1 (PICK1).

56 raction of TRPC3 with receptor for activated C-kinase-1 (RACK1) not only determines plasma membrane l

57 ion of PKCepsilon and receptor for activated C-kinase 2 (RACK2).

58 we show that PICK1 (protein interacting with C kinase), a PDZ domain-containing protein, interacts wi

59 , we created a genetically encoded reporter (C kinase activity reporter (CKAR)) to visualize the rate

60 gy transfer-based reporter for PKC activity, C kinase activity reporter (CKAR), to the plasma membran

61 recruitment of MCAK and inhibition of Aurora C kinase activity respectively.

62 t of protein kinase B/Akt and protein kinase C kinase activity, but dependent on calcium/calmodulin s

63 ishmania homologue of receptor for activated C kinase) Ag has been shown to be more durable than vacc

64 Protein that interacts with C-kinase alpha (PICK1) is a PDZ domain protein that inte

65 oshin-2 from chromosome arms by the Aurora B/C kinase, an event crucial for the efficient resolution

66 e identified RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins

67 shmania homologue of receptors for activated C kinase) and an intradermal murine infection model empl

68 actions with PICK1 (protein interacting with C-kinase) and by dephosphorylating protein kinase C alph

69 SRBC (sdr-related gene product that binds to c-kinase) and two other family members [PTRF (Pol I and

70 protein epsilonRACK (receptor for activated C-kinase), and PKC isozyme-selective inhibitors and acti

71 on) bound to RACK1, a receptor for activated C kinase, and RACK1 bound to the human Na(+)/H(+) exchan

72 eishmania homolog of receptors for activated C kinase) antigen is of interest as a vaccine candidate

73 rotein RACK1 (receptor for activated protein C kinase) as a PTPmu interacting protein.

74 large lobe, and the protein kinase A, G, and C kinase C-tail greatly impaired receptor phosphorylatio

75 on agonist psiepsilon receptor for activated C kinase caused mitoK(ATP)-dependent inhibition of MPT o

76 ember of a family of receptors for activated C kinase collectively called RACKs.

77 otein kinase/protein kinase G/protein kinase C) kinases, controls the processing phosphorylation of c

78 a biallelic splice-site mutation in protein C kinase delta (PRKCD), causing the absence of the corre

79 2-N), (b) kinase-like domain (CD16/Jak2-B), (c) kinase domain (CD16/Jak2-C), or (d) amino-terminal an

80 horing protein RACK1 (receptor for activated C kinase) eliminated the 5-HT(2) modulation of GABA(A) c

81 (for RING-finger protein that interacts with C kinase) from a yeast two-hybrid screen using the amino

82 RACK1, the first receptor for activated C kinase identified in our lab, is a selective anchoring

83 nRACK (tat-psiepsilon-receptor for activated C kinase), increased the rate of oxygen consumption in t

84 reated cells does not act in the presence of C-kinase inhibitors or cycloheximide, suggesting that si

85 e, positively or negatively, the activity of C kinase isozymes.

86 Leishmania homolog of activated receptor for c-kinase (LACK) 158-173.

87 ishmania homologue of activated receptor for c-kinase (LACK), as is the case when these mice are immu

88 its interaction with receptor for activated C kinase, or by suppressing the expression of PKCepsilon

89 e antagonistic (RACK; receptor for activated C kinase) peptide significantly inhibited GPVI and PAR-i

90 and PKC, as well as protein interacting with C kinase (PICK-1) in mGluR-LTD.

91 Z domain-containing Protein interacting with C kinase (PICK1) and N-ethylmaleimide sensitive fusion p

92 ia interactions with Protein Associated with C Kinase (PICK1).

93 otein (ABP), and protein that interacts with C-kinase (PICK1), but not the PDZ domain protein PSD-95,

94 I regulatory light chain phosphorylation and C-kinase-potentiated protein phosphatase inhibitor phosp

95 agonist, psi epsilon receptor for activated c kinase (psiepsilonRACK) can be prevented, but not reve

96 tapeptide, psiepsilon receptor for activated C-kinase (psiepsilonRACK), derived from an epsilonPKC se

97 ding proteins such as receptor for activated C kinase (RACK) 1 are involved in the targeting of signa

98 In mammalian cells the receptor of activated C kinase (RACK1) is an important scaffolding protein for

99 R, but does bind to a receptor for activated C kinase (RACK1), a 37-kDa scaffold protein, and that RA

100 1.5, K(v)beta1.3, the receptor for activated C kinase (RACK1), PKCbetaI, PKCbetaII, and PKCtheta in H

101 omal subunit protein, receptor for activated C kinase (RACK1), that are not phosphorylated in uninfec

102 olog of the mammalian receptor for activated c kinase (RACK1), that is important for parasite thermot

103 The receptor for activated C-kinase (RACK1), a conserved protein implicated in nume

104 Here we report that a receptor for activated C kinase, RACK1, is a component of messenger ribonucleop

105 of PKCepsilon and its receptor for activated C kinase, RACK2, illustrated a peroxynitrite-dependent i

106 ng proteins, such as receptors for activated C kinase (RACKs), play an important role in regulating t

107 ing proteins such as receptors for activated C kinase (RACKs).

108 -anchoring proteins (receptors for activated C kinases (RACKs)) and demonstrates a direct connection

109 tor (psiepsilonRACK [receptors for activated C kinase]) specifically targeting PKCepsilon.

110 crophage-enriched myristoylated alanine-rich C kinase substrate (MacMARCKS), a membrane-associated PK

111 crophage-enriched myristoylated alanine-rice C kinase substrate (MacMARCKS), a membrane-associated PK

112 ne binding of the myristoylated alanine-rich C kinase substrate (MARCKS) [10], but to our knowledge i

113 The myristoylated alanine-rich C kinase substrate (MARCKS) and MARCKS-related protein (

114 te domains of the myristoylated alanine rich C kinase substrate (MARCKS) and neuromodulin.

115 to phosphorylate myristoylated alanine-rich C kinase substrate (MARCKS) and release phosphatidylinos

116 C at Thr(514) and myristoylated alanine-rich C kinase substrate (MARCKS) and these effects were aboli

117 Here, we identify myristoylated alanine-rich C kinase substrate (MARCKS) as novel PSA binding partner

118 ffector domain of myristoylated alanine-rich C kinase substrate (MARCKS) binds strongly to membranes

119 redistribution of myristoylated alanine-rich C kinase substrate (MARCKS) in neurites.

120 provided that the myristoylated alanine-rich C kinase substrate (MARCKS) is a central regulatory mole

121 The myristoylated alanine-rich C kinase substrate (MARCKS) is a major cellular substrat

122 Myristoylated alanine-rich C kinase substrate (MARCKS) is a membrane-bound F-actin

123 Myristoylated alaninerich C kinase substrate (MARCKS) is a PKC substrate that cycl

124 The myristoylated alanine-rich C kinase substrate (MARCKS) is a prominent protein kinas

125 Myristoylated alanine-rich C kinase substrate (MARCKS) is an intrinsically unfolded

126 Myristoylated alanine-rich C kinase substrate (MARCKS) is an unfolded protein that

127 proteins such as myristoylated alanine-rich C kinase substrate (MARCKS) may have a role in regulatin

128 monstrated that a myristoylated alanine-rich C kinase substrate (MARCKS) peptide comprising the phosp

129 responding to the myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation site domain

130 tudy reveals that myristoylated alanine-rich C kinase substrate (MARCKS) protein coordinates activati

131 hosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) protein in these cells.

132 ne binding of the myristoylated alanine-rich C kinase substrate (MARCKS) requires both its myristate

133 tor region of the myristoylated alanine-rich C kinase substrate (MARCKS) self-assembles into membrane

134 ing domain of the myristoylated alanine rich C kinase substrate (MARCKS) were synthesized and derivat

135 or domain (ED) of myristoylated alanine-rich C kinase substrate (MARCKS) which interacts with PSA wit

136 viously found the myristoylated alanine-rich C kinase substrate (MARCKS), a key protein kinase C (PKC

137 entrations of the myristoylated alanine-rich C kinase substrate (MARCKS), a major cellular substrate

138 ffector domain of myristoylated alanine-rich C kinase substrate (MARCKS), a major protein kinase C su

139 Myristoylated Alanine-Rich C Kinase Substrate (MARCKS), a substrate of protein kina

140 tor domain of the myristoylated alanine-rich C kinase substrate (MARCKS), or a peptide corresponding

141 g a COOH-terminal myristoylated alanine-rich C kinase substrate (MARCKS)-related domain that caps and

142 KS (also known as myristoylated alanine-rich C kinase substrate (MARCKS)-related protein) is a member

143 derived from the myristoylated alanine-rich C kinase substrate (MARCKS-PSD, Calbiochem) for use in c

144 hosphorylation of myristoylated alanine-rich C kinase substrate (phospho-MARCKS) at the phosphorylati

145 of phosphorylated myristoylated alanine-rich C kinase substrate (pMARCKS) from the membrane.

146 ein 12 (AKAP12; also known as src-suppressed C kinase substrate (SSeCKS) and Gravin) is a multivalent

147 0 appears to be a myristoylated alanine-rich C kinase substrate analog.

148 of phosphorylated myristoylated alanine-rich C kinase substrate and its subsequent diffusion and deph

149 ng domains of the myristoylated alanine-rich C kinase substrate and neuromodulin were previously foun

150 hosphorylation of myristoylated alanine-rich C kinase substrate by membrane-localized PKC constitutes

151 lipid ligand MED (myristoylated alanine-rich C kinase substrate effector domain) or elevated concentr

152 PKC-dependent myristoylated alanine-rich C kinase substrate phosphorylation in epsilonPKC knock-o

153 new member of the myristoylated alanine-rich C kinase substrate protein family.

154 se anchor protein-myristoylated alanine-rich C kinase substrate protein that may facilitate localized

155 on of eGFP-tagged myristoylated alanine-rich C kinase substrate protein) required oscillatory DAG pro

156 horylation of the myristoylated alanine-rich C kinase substrate protein, a PKC substrate, in phorbol

157 ain of vertebrate myristoylated alanine-rich C kinase substrate proteins.

158 hosphorylation of myristoylated alanine-rich C kinase substrate was decreased, and mRNA levels of nuc

159 peripheral (e.g., myristoylated alanine-rich C kinase substrate) and integral (e.g., the epidermal gr

160 substrate MARCKS (myristoylated alanine-rich C kinase substrate) as a potential target molecule for k

161 e MARCKS protein (myristoylated alanine-rich C kinase substrate) is an actin- and calmodulin-binding

162 SSeCKS (Src-suppressed C kinase substrate), also called gravin/AKAP12, is a lar

163 eins (radixin and myristoylated alanine-rich C kinase substrate), and Rab proteins.

164 MDA receptors and myristoylated alanine-rich C kinase substrate).

165 crophage-enriched myristoylated alanine-rice C kinase substrate).

166 Jun was identified as SSeCKS (Src-suppressed C kinase substrate).

167 on site domain of myristoylated alanine-rich C kinase substrate, a conserved catalytic domain, and fo

168 as Raf-1 kinase, myristoylated alanine-rich C kinase substrate, and SOS.

169 Pleckstrin, the platelet and leukocyte C kinase substrate, is a prominent substrate of PKC in p

170 The myristoylated alanine-rich C kinase substrate, or MARCKS protein, is a widely expre

171 rate that Lck and myristoylated alanine-rich C kinase substrate, two main myristoylated kinases in T

172 SSeCKS (pronounced essex) for Src Suppressed C Kinase Substrate.

173 Myristoylated alanine-rich C-kinase substrate (MARCKS) and F1/GAP-43 (B-50/neuromod

174 preconditioning: myristoylated, alanine-rich C-kinase substrate (MARCKS) and fascin.

175 hosphorylation of Myristoylated alanine-rich C-kinase substrate (MARCKS) and LAMC2 protein level were

176 n-binding protein myristoylated alanine-rich C-kinase substrate (MARCKS) as a key mediator of the H(2

177 in of the protein myristoylated alanine-rich C-kinase substrate (MARCKS) bind to phosphatidylserine e

178 ns, myosin II and myristoylated alanine-rich C-kinase substrate (MARCKS) in this process.

179 phosphorylate the myristoylated alanine-rich C-kinase substrate (MARCKS) motif of DGKzeta, we tested

180 tor domain of the myristoylated alanine-rich C-kinase substrate (MARCKS) protein was examined.

181 rized MK protein, myristoylated alanine-rich C-kinase substrate (MARCKS), which was upregulated 3.4-

182 jor PKC substrate, myristolated alanine-rich C-kinase substrate (MARCKS).

183 on target is the myristoylated, alanine-rich C-kinase substrate (MARCKS).

184 ffector domain of myristoylated alanine-rich C-kinase substrate (MARCKS-ED) has been demonstrated to

185 tor domain of the myristoylated alanine-rich C-kinase substrate (MARCKS-ED) is a highly basic, unstru

186 Src-suppressed C-kinase substrate (SSeCKS, the rodent orthologue of hum

187 in mice that the myristoylated alanine-rich C-kinase substrate protein (MARCKS), a prominent cellula

188 role of MARCKS (myristoylated, alanine-rich C-kinase substrate) in dendrites of 3-week-old hippocamp

189 MARCKS (myristoylated alanine-rich C-kinase substrate) is a major substrate for protein kin

190 ylated (inactive) myristoylated alanine-rich C-kinase substrate, a PKC target that promotes arborizat

191 njury molecule 1, annexin A3, src-suppressed C-kinase substrate, and CD44) and showed a higher prolif

192 Mice lacking the myristoylated alanine-rich C-kinase substrate, or MARCKS protein, exhibit abnormali

193 of the STICK (substrates that interact with C-kinase) superfamily of PKC-binding proteins.

194 tor (sdr)-related gene product that binds to c-kinase] was isolated in a yeast two-hybrid screening,