ライフサイエンスコーパス: C-terminal domain

1 the various heptad repeat motifs within the C-terminal domain.

2 ugh phosphorylation of the RNA polymerase II C-terminal domain.

3 analysis to investigate the function of the C-terminal domain.

4 nsistent with a more folded and less dynamic C-terminal domain.

5 Lpro chiefly engages human ISG15 through its C-terminal domain.

6 al dinucleotide binding domain and a smaller C-terminal domain.

7 binds in the hydrophobic pocket on the Rev1 C-terminal domain.

8 omain, a hypervariable domain, and an acidic C-terminal domain.

9 ld (OB-fold) and an intrinsically disordered C-terminal domain.

10 RNA, or expression of the dominant-negative C-terminal domain.

11 ike alpha/beta/alpha sandwich and an unusual C-terminal domain.

12 domain on the cell surface and a periplasmic C-terminal domain.

13 teracting with RAD51 recombinase through its C-terminal domain.

14 tic elements are larger and contain an extra C-terminal domain.

15 identified at interdomain interfaces of the C-terminal domain.

16 icing isoform (LIG3beta) that differs in the C-terminal domain.

17 an N-terminal domain, a middle domain, and a C-terminal domain.

18 urrents when expressed in the absence of the C-terminal domain.

19 P orthologues share an extended, cytoplasmic C-terminal domain.

20 through adjacent conserved interfaces in its C-terminal domain.

21 isite for full activity and is mediated by a C-terminal domain.

22 is tightly regulated in cis by the globular C-terminal domain.

23 ture of the four-helix bundle that forms the C-terminal domain.

24 at this pore opens independent of its unique C-terminal domain.

25 omplex, which is also controlled by MARCH5's C-terminal domain.

26 istinct coiled-coil domains: the central and C-terminal domains.

27 ide a tunnel formed by the two RecA-like and C-terminal domains.

28 r RNA binding by large rearrangements of the C-terminal domains.

29 ble interaction between the protein's N- and C-terminal domains.

30 esidues located between the conserved N- and C-terminal domains.

31 mains to the ATPase, Rubisco recognition and C-terminal domains.

32 concentrated in the highly conserved N- and C-terminal domains.

33 N-terminal, globular, and long, unstructured C-terminal domains.

34 t it bound strongly to monomeric CRP via its C-terminal domains.

35 h the binding affinities of conserved N- and C-terminal domains.

36 currently circulating H1N1 viruses, and its C-terminal domain (38 amino acids).

37 antibody fragment show that the doublecortin C-terminal domain adopts the same well defined ubiquitin

38 he interaction of the Msm RNAP alpha-subunit C-terminal domain (alphaCTD) with DNA, and we provide ev

39 lin or IGF-1 treatment, for which the unique C-terminal domain (amino acids 223-276) is essential.

40 q/11 Here, we identified a region within the C-terminal domain (amino acids 852-876) that is necessar

41 ed by the protein's intrinsically disordered C-terminal domain and an incipient amphipathic alpha-hel

42 d two decavanadate-binding sites, one in the C-terminal domain and another in the intersubunit MHR in

43 Another VHH appears to recognize the LF C-terminal domain and exhibits a kinetic effect on subst

44 y, the protective variant lacks a functional C-terminal domain and is unable to recruit the E3 ubiqui

45 on in translation termination depends on its C-terminal domain and its interaction with the N-terminu

46 +) during hyperosmotic stress latter via its C-terminal domain and regulates transport activity accor

47 tween TMR (donor) bound to a cysteine in the C-terminal domain and the carotenoid (acceptor) increase

48 Biochemical data showed that Rad26 uses its C-terminal domain and the flanking kinase-docking motif

49 id-protein interactions, especially with the C-terminal domain and the functional important gating he

50 proenzyme's interface between the shielding C-terminal domain and the main core provides insights in

51 ted in the linker region, between the N- and C-terminal domains and a single C-terminal residue.

52 that lipid binds between the N-terminal and C-terminal domains and that separation of the two domain

53 d, a dimerization domain, a middle domain, a C-terminal domain, and a centrally located open cavity.

54 the associated Zwilch subunit bind Spindly's C-terminal domain, and we identify a specific Zwilch mut

55 gE also contains an intrinsically disordered C-terminal domain, and we show here that this domain spe

56 s that serine residues 2 and 5 of the pol II C-terminal domain are O-GlcNAcylated, suggesting an over

57 lular membrane surface and the intracellular C-terminal domain are visible in the structure.

58 ved by proprotein convertases to release the C-terminal domain as an active ligand dimer.

59 a potential oligomerization interface in the C-terminal domain as well as a conserved oligomerization

60 RapZ at 3.40 A and 3.25 A, and its isolated C-terminal domain at 1.17 A resolution.

61 (PKA)-mediated phosphorylation of the STEVOR C-terminal domain at a specific serine residue (S324).

62 of RapZ possesses a kinase fold, whereas the C-terminal domain bears closest homology to a subdomain

63 e-binding N-terminal domain and a regulatory C-terminal domain binding S-adenosyl-l-methionine (AdoMe

64 In the absence of coiled-coil formation, the C-terminal domain bound liposomes and ProP concentrated

65 solution crystal structure of the human ELL2 C-terminal domain bound to its 50-residue binding site o

66 rmore, full-length GST-mu1A and the GST-mu1A C-terminal domain, but not the GST-mu1A N-terminal domai

67 ift mutation in CORO1A disrupting the last 2 C-terminal domains by replacing 61 amino acids with a no

68 RS is the single exception, with an appended C-terminal domain (C-Ala) that is conserved from prokary

69 ob1 phosphorylation at specific sites in its C-terminal domain (C-Fob1), which also regulates long-ra

70 Moreover, the free C-terminal domain can rapidly decondense ParB networks i

71 n lipoxygenases, the topologically conserved C-terminal domain catalyzes the oxidation of polyunsatur

72 -type helicases share a conserved regulatory C-terminal domain cluster that includes an oligonucleoti

73 The RNA polymerase II largest subunit C-terminal domain consists of repeated YSPTSPS heptapept

74 xpression of the multifunctional BRCT (BRCA1 C-terminal) domain-containing PTIP (Pax transactivation

75 Deletion of the C-terminal domain converted CsxA into a distributive enz

76 The function of the XND1 C-terminal domain could be partially replaced by RBR fus

77 Here, we characterized a novel cysteine-rich C-terminal domain (CRD), which is present in most class

78 ns two P1-P2 protein dimers with a conserved C- terminal domain (CTD) critical for the interaction wi

79 rough its interaction with RNA Polymerase II C-terminal domain (CTD) and affecting the expression lev

80 HKU1 virus uses its S1 subunit C-terminal domain (CTD) and not the N-terminal domain li

81 tructure shows GSK1264 buried between the IN C-terminal domain (CTD) and the catalytic core domain.

82 ranslational modifications on the RNA pol II C-terminal domain (CTD) and the chromatin template.

83 onstructs showed that both the intracellular C-terminal domain (CTD) and the loop region between the

84 major matrix-exposed loop of Tim23, with the C-terminal domain (CTD) binding Tim17 as well.

85 ains a repetitive, intrinsically disordered, C-terminal domain (CTD) composed of heptads of the conse

86 e function of Hfq's intrinsically disordered C-terminal domain (CTD) has remained unclear.

87 The C-terminal domain (CTD) is deemed dispensable for capsid

88 The H1 C-terminal domain (CTD) localizes primarily to a single

89 r connecting the N-terminal domain (NTD) and C-terminal domain (CTD) of AhpF suggests that the enzyme

90 interactions between helix 9 segments of the C-terminal domain (CTD) of CA.

91 A-site tRNA, including contacts between the C-terminal domain (CTD) of EF-4 and the acceptor helical

92 Many of these proteins bind the C-terminal domain (CTD) of FtsZ, which serves as a hub f

93 malian cells, capsid assembly depends on the C-terminal domain (CTD) of HBc, in contrast to other ass

94 The C-terminal domain (CTD) of hepadnavirus core protein is

95 .IMPORTANCE The phosphorylation state of the C-terminal domain (CTD) of hepatitis B virus (HBV) core

96 of VSV by its polymerase are provided by the C-terminal domain (CTD) of P.

97 the changing phosphorylation pattern on the C-terminal domain (CTD) of polymerase subunit Rpb1 durin

98 The C-terminal domain (CTD) of RNA polymerase II in eukaryot

99 The C-terminal domain (CTD) of RNAP II recruits chromatin mo

100 atively regulated by ATP, which binds to the C-terminal domain (CTD) of Sirt1.

101 The C-terminal domain (CTD) of Ska1 binds microtubules and w

102 ssembly and maturation switch that spans the C-terminal domain (CTD) of the capsid (CA) region and th

103 lves the catalytic core domain (CCD) and the C-terminal domain (CTD) of the integrase.

104 h the post-translational modification of the C-terminal domain (CTD) of the largest subunit of RNA po

105 topo II-targeted drugs is influenced by the C-terminal domain (CTD) of the topo II isoforms and by a

106 ent work showed that the enzymatically inert C-terminal domain (CTD) of TOP2 and its posttranslationa

107 The Ska1 C-terminal domain (CTD) recruits protein phosphatase 1 (

108 horylation of the RNA polymerase II (Pol II) C-terminal domain (CTD) regulates transcription of prote

109 The GluN2B cytoplasmic C-terminal domain (CTD) represents an alternative therap

110 y folded in an N-terminal domain (NTD) and a C-terminal domain (CTD) separated by a central ionic lay

111 ment to gene promoters and decreased RNAP II C-terminal domain (CTD) Ser2 phosphorylation during VHSV

112 proteins, SlmA interacts with the conserved C-terminal domain (CTD) that is connected to the FtsZ co

113 Hfq possesses an intrinsically disordered C-terminal domain (CTD) that may tune the function of th

114 RNA polymerase II contains a long C-terminal domain (CTD) that regulates interactions at t

115 Mfa5 is predicted to have a C-terminal domain (CTD) that uses the type IX secretion

116 find that Rbfox interacts with LASR via its C-terminal domain (CTD), and this domain is essential fo

117 avirus (PV) E1 helicase contains a conserved C-terminal domain (CTD), located next to its ATP-binding

118 ctor PCF11 on its RNA polymerase II (Pol II) C-terminal domain (CTD)-interacting domain (CID).

119 P-TEFb-associated RNA polymerase II (RNAPII) C-terminal domain (CTD)-Ser7 phosphorylation at the WNT3

120 -fold higher abundance of a novel ('-12-40') C-terminal domain (CTD)-variant in the SCN.

121 l degradation through dynamic effects on the C-terminal domain (CTD).

122 robial activity through a peptide within its C-terminal domain (CTD).

123 e interactions are negatively regulated by a C-terminal domain (CTD).

124 e phosphorylation state of its large subunit C-terminal domain (CTD).

125 t disrupt its kinase activity and remove its C-terminal domain (CTD).

126 ral ILS target even in the absence of Ntr1's C-terminal-domain (CTD) and Ntr2.

127 important differences in how the Rb and p107 C-terminal domains (CTDs) associate with the coiled-coil

128 ures, such as the exonuclease/polymerase and C-terminal domains (CTDs) of catalytic subunits bound to

129 We have made three mouse lines where the C-terminal domains (CTDs) of endogenous AMPA receptors (

130 ator complex subunit 9 (IntS9) through their C-terminal domains (CTDs).

131 at atmospheric pressure for a mutant of the C-terminal domain (CTL9) from pressure dependent ZZ-exch

132 te the mitotic DSB repair properties of Ctp1 C-terminal domain (ctp1-CD) mutants that were reported t

133 inal domains (D1-D4) and the first predicted C-terminal domain (D5) of MtTOP1 was expressed and found

134 ed in an apparent conformational change by a C-terminal domain-derived alpha-helix.

135 pendent, and phosphomimetic mutations in the C-terminal domain did not result in unmasking of the cat

136 ycobacterial F-ATP synthases deletion of the C-terminal domain enabled ATPase and proton-pumping acti

137 However, the C-terminal domain failed to transfer manganese transport

138 arest the membrane) and is arranged with its C-terminal domain (FliGC) resting on the middle domain (

139 Four cytosolic C-terminal domains form an umbrella-like structure with

140 ity mutants interacted with the SaPIbov1 Stl C-terminal domain, formed DutNM1-Stl heterodimers, and c

141 med between two IN tetramers, with a pair of C-terminal domains from flanking tetramers completing th

142 ng demonstrate that only the top part of the C-terminal domain (from the residue A110 to E118) dissoc

143 ved N-terminal ATP PPase domain and a unique C-terminal domain harboring the putative catalytic site.

144 i-motif binding activity, implying that the C-terminal domain has a distinct substrate specificity.

145 ring (SAXS) data revealed that the protein's C-terminal domain has a PG-binding-competent conformatio

146 gamma-glutamyl ligase activity, whereas the C-terminal domain has sequence similarity to an FMN-depe

147 The HlyII toxin has a unique 94 amino acid C-terminal domain (HlyIIC).

148 expressed a dominant-negative form of a 4.1N C-terminal domain (HSV 4.1N-CTD), which prevents endogen

149 ritical role for the 15 residues in the PA-X C-terminal domain in degrading mRNAs in both the cytopla

150 The roles of phospholipids and the C-terminal domain in subcellular localization of ProP we

151 a Mycobacterium-specific, 36-amino acid long C-terminal domain in the nucleotide-binding subunit alph

152 and its implications for the role of N- and C-terminal domains in catalysis.

153 the role of its RASGAP C-terminal (RGCT) and C-terminal domains in the interactions with RHO proteins

154 e to the absence of electron density for the C-terminal domains in the x-ray structure.

155 demonstrate the importance of intact CORO1A C-terminal domains in thymic egress and T-cell survival,

156 tamate-gamma-semialdehyde dehydrogenase, and C-terminal domains, including an extended interdomain tu

157 nti-PrP antibodies targeting epitopes in the C-terminal domain induce currents, and cause degeneratio

158 ongly dependent on both intracellular N- and C-terminal domains; insertions of an unstructured peptid

159 phosphatase activities, and both the N- and C-terminal domains interact with substrates to increase

160 rate liposomes, the overall structure of the C-terminal domain is in good agreement with crystallogra

161 The C-terminal domain is involved in oligomeric interactions

162 ed on the face of the beta-helix whereas the C-terminal domain is likely involved in carbohydrates bi

163 terocomplex (SEPT2/SEPT6/SEPT7), the role of C-terminal domain is not fully established, and this is

164 The C-terminal domain is permissive to cytoplasmic shuttling

165 The C-terminal domain is relatively unstructured in the mono

166 on of excitation energy quenching, while the C-terminal domain is the regulatory domain that senses l

167 CL59 binds to the C-terminal domain IV of gH, while CL40 binds to a site o

168 -length IL1RAPL1 and mutants lacking part of C-terminal domains leads to simplified neuronal arboriza

169 of NTD, and name this truncated variant the C-terminal domain-like carotenoid protein (CCP).

170 cessed by CO2 in a manner dependent on a key C-terminal domain located in its transactivation domain.

171 monstrates that two basic loops in the mVP40 C-terminal domain make important contributions to anioni

172 m formation by Bordetella lacking the mature C-terminal domain (MCD), suggesting the direct interacti

173 etween their N-terminal domains, whereas the C-terminal domains mediate longitudinal interactions wit

174 matics predicts that MOSP consists of N- and C-terminal domains, MOSP(N) and MOSP(C).

175 he MAD2-interaction motif (MIM), both N- and C-terminal domains (NTD and CTD) of MAD1 also contribute

176 but is atypical in having a non-homologous, C-terminal domain of approximately 20 kDa and at least o

177 The positively charged C-terminal domain of ArfA anchors in the mRNA entry chan

178 mouse model carrying a mutation in the BRCA1 C-terminal domain of BRCA1.

179 1, via amino acids 20-90, interacts with the C-terminal domain of BRCA2, and that this interaction is

180 ylation and facilitates RAD51 binding to the C-terminal domain of BRCA2.

181 f the compounds showed potent binding to the C-terminal domain of CA and were found to block viral re

182 zed novel splice variants of the cytoplasmic C-terminal domain of Cav1.4 Ca(2+) channels that regulat

183 AA) into the CaS protein-binding site in the C-terminal domain of CaV2.1 channels in mice, and tested

184 5, 279/282, 365, 368, and 373 located in the C-terminal domain of connexin43 (Cx43) into glutamic aci

185 roteolysis of spheroplasts revealed that the C-terminal domain of CpaB is exposed to the periplasm, s

186 We conclude that the C-terminal domain of Ctp1 is required for both efficient

187 the elucidation of the NMR structures of the C-terminal domain of EB1 in the free form and complexed

188 The MoMLV RT interacts with the C-terminal domain of eRF1 via its RNase H domain to ster

189 induce a conformational rearrangement in the C-terminal domain of ExoU.

190 We also present crystal structures of the C-terminal domain of FbiB in apo-, F420-0-, and FMN-boun

191 We show that the rotated C-terminal domain of FIN219 alters ATP binding and the c

192 To further humanize these clones, the C-terminal domain of gpASNase1 was replaced with that of

193 Previously, we have shown that the C-terminal domain of Haemophilus influenzae LpoA (HiLpoA

194 ependent conformational rearrangement of the C-terminal domain of heme binding protein (PhuS) is requ

195 thermal calorimetry, which suggests that the C-terminal domain of hISG15 is principally responsible f

196 Lpro was solved to 2.4 A in complex with the C-terminal domain of hISG15.

197 nown dodecapeptide assembly inhibitor to the C-terminal domain of HIV-1 CA (capsid).

198 Unexpectedly, the C-terminal domain of KorA is structurally similar to the

199 sion and that CHMP7 can bind directly to the C-terminal domain of LEM2 in vitro.

200 s an important role in PB formation, but the C-terminal domain of Lsm4 in most eukaryotes is an RGG d

201 We show that the C-terminal domain of lyspersin, a subunit of BLOC-1-rela

202 arboxymethylation-that is carried out by the C-terminal domain of MccB and the MccS enzyme that produ

203 terminal domain of MotA [MotA(NTD)], and the C-terminal domain of MotA [MotA(CTD)]), molecular modeli

204 Recruitment of A20 to the C-terminal domain of NEMO represents a novel mechanism l

205 c family tyrosine kinase, interacts with the C-terminal domain of NOX4.

206 The C-terminal domain of nsp5 was shown to be required for t

207 Our work reveals a dual role for the C-terminal domain of ParB as both a DNA binding and brid

208 The C-terminal domain of Pdc is located outside the central

209 Endorepellin, the C-terminal domain of perlecan, is an angiostatic molecul

210 A polymerase (RNAP), also interacts with the C-terminal domain of PigR, thus anchoring the (MglA-SspA

211 tion in yeast are mediated through the small C-terminal domain of Pol3.

212 structural model of DnaB complexed with the C-terminal domain of primase, we found that Ile-85 is lo

213 this inhibitory effect required the globular C-terminal domain of PrP(C), which has not been previous

214 ough fibrils in the inoculum lack the entire C-terminal domain of PrP, brains of clinically sick mice

215 ts N-terminal prion-like domain (PLD) to the C-terminal domain of RNA polymerase II.

216 , we determined the crystal structure of the C-terminal domain of RopB.

217 We then map SUMOylation sites to the C-terminal domain of septins belonging to the SEPT6 and

218 nt and of type I IFN but required a distinct C-terminal domain of STING that activates NF-kappaB.

219 A [4Fe4S](2+) cluster in the C-terminal domain of the catalytic subunit of the eukary

220 A small C-terminal domain of the catalytic subunit Pol3 carries

221 nse variants identified in the intracellular C-terminal domain of the GluN2B NMDAR subunit.

222 We studied here the intrinsically disordered C-terminal domain of the Hendra virus nucleoprotein (NTA

223 The C-terminal domain of the human Ino80 subunit (Ino80CTD)

224 of the iron-sulfur cluster buried inside the C-terminal domain of the large primase subunit (p58C).

225 Here we show that the C-terminal domain of the large subunit (p58C) plays a ma

226 at multiple magnetic field strengths on the C-terminal domain of the nucleoprotein of Sendai virus,

227 eby shows how the kinase and its target, the C-terminal domain of the polymerase, control Med-PIC int

228 o key complexes, the human primosome and the C-terminal domain of the primase large subunit (p58C) wi

229 ggested that conformational changes within a C-terminal domain of the toxin might be involved in the

230 that MB-10 binds to a specific pocket in the C-terminal domain of Tim44 of the protein-associated mot

231 The C-terminal domain of TPX2 contributes to the localizatio

232 We found that the C-terminal domain of TPX2 contributes to the localizatio

233 polar spindle formation in vivo requires the C-terminal domain of TPX2.

234 e focus on order-disorder transitions in the C-terminal domain of troponin I, which have important im

235 The C-terminal domain of Tsc1 (998-1,164 aa) forms a homodim

236 FtsKgamma interacts with the C-terminal domain of XerD, above a cleft where XerC is t

237 The binding interface is centered on the C-terminal domain of YscU.

238 The N- and C-terminal domains of all gasdermins possess lipid-bindi

239 The N-terminal and C-terminal domains of CA (NTD and CTD, respectively) eng

240 now determined the crystal structure of the C-terminal domains of eIF2D at 1.4-A resolution.

241 Zn-binding tetracysteine motifs seen in the C-terminal domains of Escherichia coli topoisomerase I.

242 Both N- and C-terminal domains of Gal-9 bound m4-1BB, but with lower

243 two molecules of gamma-tubulin bound to the C-terminal domains of GCP2 and GCP3.

244 We show that the C-terminal domains of Gea1 and Gea2 toggle roles in the

245 s on the homo/heterotypical affinity for the C-terminal domains of human septins belonging to the SEP

246 In this study, we show that the N and C-terminal domains of Orai1 synergistically contribute t

247 ome association of peptides representing the C-terminal domains of ProP orthologues and variants in v

248 strate intramolecular docking between N- and C-terminal domains of PrP(C), revealing a novel auto-inh

249 te a direct physical interaction between the C-terminal domains of topoisomerase I (TopoI-CTDs) and t

250 We find that both the N- and C-terminal domains of TTP are involved in an interaction

251 bind ssDNA and four intrinsically disordered C-terminal domains of unknown structure that interact wi

252 s tightly into the PBS while leaving the OCP C-terminal domain on the exterior of the complex.

253 Capsid recognition is mediated by C-terminal domains on TRIM5alpha (SPRY) or TRIMCyp (cycl

254 The RNA polymerase II C-terminal domain phosphatase-like protein FIERY2 (FRY2;

255 ase-like protein FIERY2 (FRY2; also known as C-TERMINAL DOMAIN PHOSPHATASE-LIKE1 [CPL1]) plays multip

256 Here we report that the MARCH5 C-terminal domain plays a critical role in degradation o

257 , sub-states in the folded ensemble of CaM's C-terminal domain present chemically and sterically dist

258 GlyA1 includes an additional C-terminal domain previously unobserved in GH3 members,

259 that placed the cofactor-binding site in the C-terminal domain rather than the anticipated Rossmann f

260 linked through an invariant GGKGG motif to a C-terminal domain (referred to as Sde2-C).

261 n is the active part of the protein, and the C-terminal domain regulates the activity.

262 300 could completely accommodate the GstDnaB C-terminal domain (residues 301-461).

263 The C-terminal domain (residues 365-524) is sufficient to pi

264 thermodynamic stability measurements on the C-terminal domains (residues 90-231) of two PrP variants

265 Our data show that, in the intermediate, the C-terminal domain retains a folded conformation that is

266 ructure of the Saccharomyces cerevisiae Stu2 C-terminal domain, revealing a 15-nm parallel homodimeri

267 Structural analysis of the C-terminal domain reveals a dimer with a lysine-rich sur

268 The crystal structure of the GSDMB C-terminal domain reveals the structural impact of the a

269 conformational change of subunit H, with its C-terminal domain rotating ~150 degrees from a position

270 Structural insight into the C-terminal domain's architecture and localization mechan

271 e bioactive LN-511-E8 fragment carrying only C-terminal domains showed similar efficacy as full-lengt

272 Although the isolated C-terminal domain shows two-state folding, we find that

273 Headers are followed by one or more diverse C-terminal domains, such as restriction endonuclease (RE

274 correlate primarily with the dynamics of the C-terminal domain, supporting a directional preference i

275 wo separate suppressor mutations in the Art1 C-terminal domain that allele-specifically restore endoc

276 Cleavage generates a C-terminal domain that contains a sterile-alpha-motif-li

277 a series of truncation mutants, we mapped a C-terminal domain that is necessary and sufficient for C

278 d acidic N-terminal domain; and (2) a folded C-terminal domain that tethers GPIHBP1 to the cell membr

279 collagen-like neck bearing a globular head (C-terminal domain) that promotes glycoprotein trimerizat

280 B forms a subdomain between the plug and the C-terminal domain, that 'clamps' the coiled coil of the

281 domains, such as the black widow latrotoxin C-terminal domain, that are uninterrupted in bacteriopha

282 all-and-chain" architecture, with a globular C-terminal domain (the ball) preceded by a long intrinsi

283 l GTPase domain, an N-terminal domain, and a C-terminal domain; the latter is predicted to form a coi

284 d of the N-terminal domains, and a C-tier of C-terminal domains; the C-tier contains the motor.

285 onstrated that transfer of the mycobacterial C-terminal domain to a standard F-ATP synthase alpha sub

286 minus of DnaC interact with a site in DnaB's C-terminal domain to trap it as an open ring.

287 l change permitting the insertion of the LOK C-terminal domain to wedge apart the membrane and F-acti

288 the propensity of the intrinsically unfolded C-terminal domains to drive pathological aggregation.

289 icate that residues in the transmembrane and C-terminal domains together confer optimal manganese tra

290 Though the C-terminal domain was similar to DNA-binding regions of

291 The interaction between the N- and C-terminal domains was not DNA-PKcs-dependent, and phosp

292 nd valine 597 residues present in the Ldgp63 C-terminal domain were critical for binding with LdSec24

293 idues His-333 and His-350 in the cytoplasmic C-terminal domain were required for full activity.

294 We also found that some of the C-terminal domains were sufficient to direct green fluor

295 EC3G deaminates single-stranded DNAs via its C-terminal domain, whereas the N-terminal domain is cons

296 dependent condensation of the linker histone C-terminal domain, which is critical for stabilizing hig

297 agment functions to provide stability to the C-terminal domain, which is necessary for lethal toxicit

298 n vitro and increases the flexibility of the C-terminal domain, while a combination of FAD and the in

299 rized group of HRPKSs was found to contain a C-terminal domain with significant homology to carnitine

300 tion of ProP results from association of its C-terminal domain with the anionic lipid-enriched membra