ライフサイエンスコーパス: C-terminal tail

1 rs that contained only one tyrosine in their C-terminal tail.

2 rdering of a generally disordered 20-residue C-terminal tail.

3 americ N-terminal domain and an unstructured C-terminal tail.

4 residues on a surface patch and the flexible C-terminal tail.

5 tory amino acid residues located in the Cx43 C-terminal tail.

6 nteracted with the inhibitory phosphorylated C-terminal tail.

7 tion with clarin-1 transcript, requiring its C-terminal tail.

8 our-helix bundle fold stabilized by its long C-terminal tail.

9 phosphorylated at four serines in its 18-aa C-terminal tail.

10 ortant of which is the autoinhibition by its C-terminal tail.

11 (K40) or detyrosination of the alpha-tubulin C-terminal tail.

12 9), Ser(350), Ser(357), and Ser(360)) in the C-terminal tail.

13 Golgi membranes through interaction with the C-terminal tail.

14 s in that Dexras1 contains an extended 7 kDa C-terminal tail.

15 ghly conserved globular core and a divergent C-terminal tail.

16 a truncated form of Drs2p, which lacked the C-terminal tail.

17 despite the presence of an exposed cytosolic C-terminal tail.

18 quent in the membrane-proximal region of the C-terminal tail.

19 1N through a membrane-proximal domain in the C-terminal tail.

20 I (FNIII)-like domain attached to a flexible C-terminal tail.

21 egulatory domain and phosphorylation of H1.2 C-terminal tail.

22 ted to extend the Ser65 loop and shorten the C-terminal tail.

23 tor phosphorylation, often at the receptor's C-terminal tail.

24 ed S-shaped Myo1c with Neph1 attached to its C-terminal tail.

25 panning regions and a required intracellular C-terminal tail.

26 cies measured to the alpha1S II-III loop and C-terminal tail.

27 ining motifs homologous to the alpha-tubulin C-terminal tail.

28 two G domains together at their unstructured C-terminal tails.

29 wap involving the two N-terminal helices and C-terminal tails.

30 ts of GroES and the GroEL apical domains and C-terminal tails.

31 s well as to the normally unstructured GroEL C-terminal tails.

32 been linked to a "tubulin code" in which the C-terminal tail, a region of substantial sequence diverg

33 sphorylated on four clustered Ser/Thr on its C-terminal tail (aa 380-385) and these phosphorylations

34 es a PDZ domain, a BAR domain, and an acidic C-terminal tail (ACT).

35 AE1's C-terminal tail (AE1C) contains multiple potential membr

36 e punctuated by a cytoplasmic loop, with the C-terminal tail also occupying the cytoplasm.

37 The C-terminal tails also impact the conformational state of

38 s to cognate peptides within their partners' C-terminal tails, analogous to the "safety belt" binding

39 Truncations of the intracellular C-terminal tail and an AAA substitution of the putative

40 d with increased PTEN phosphorylation in the C-terminal tail and its localization to chromatin.

41 completed by His103 and His105 of the S100A9 C-terminal tail and previously identified as the high-af

42 interacts with and neutralizes VapC via its C-terminal tail and regulate TA operon transcription via

43 onstrate that spinophilin interacts with the C-terminal tail and second intracellular loop of Group I

44 estriction factor SAMHD1 at either its N- or C-terminal tail and targets it for destruction by the ce

45 A17 is phosphorylated exclusively within the C-terminal tail and that this region is a direct substra

46 nds the large FtsZ globular core rather than C-terminal tail, and the presence of two adjacent pocket

47 omain, rather than the presence of the N- or C-terminal tails, appears to be important for p53-CRM1 i

48 To determine whether these C-terminal tails are intrinsically disordered regions, w

49 each provide evidence that the EGFR and HER3 C-terminal tails are intrinsically disordered with exten

50 ates in the intrinsically disordered tubulin C-terminal tails, are crucial for the biogenesis and sta

51 on is cell autonomous and is mediated by its C-terminal tail, as only Kif5Aa and chimeric motors cont

52 Increased negative charge in this C-terminal tail balances positively charged residues, al

53 we serendipitously discovered that its free C-terminal tail binds PDZ domains (when unphosphorylated

54 that a peptide corresponding to the Atlastin C-terminal tail binds to membranes as a parallel alpha h

55 s showed that the large central loop and the C-terminal tail both reside in the cytoplasm and are sep

56 imultaneously bind DNA in the absence of the C-terminal tail, but the tail modulates DNA binding and

57 Src is inhibited via phosphorylation of its C-terminal tail by another kinase, C-terminal Src kinase

58 in which beta5-strand slippage retracts the C-terminal tail by two residues into the Ub core.

59 f the microtubule surface, including tubulin C-terminal tails by CAP-Gly.

60 al tyrosine-based motif localized within the C-terminal tail (C-tail) domain.

61 The C-terminal tail (C-tail) of AGC kinase domains is a high

62 se upon deletion of the non-conserved acidic C-terminal tail (C-tail) of the CTDs has been reported.

63 ain, followed by an acidic region (AR) and a C-terminal tail (C-tail) that have been shown to regulat

64 ly disordered linkers (IDLs) within the four C-terminal tails connected to the ssDNA binding domains.

65 interact strongly with beta-arrestins via a C-terminal tail containing clusters of serine/threonine

66 chemical characterization suggested that the C-terminal tail containing the GG motif interacts with t

67 The extramembrane C-terminal tail contains a completely conserved proline,

68 how that the K(2P)2.1 (TREK-1) intracellular C-terminal tail (Ct), a major sensory element of the cha

69 II is associated with phosphorylation of its C-terminal tail (CTD).

70 Bioinformatics analyses indicated that the C-terminal tails (CTs) of Toc159 possess physicochemical

71 , Drosophila cryptochrome (dCRY), contains a C-terminal tail (CTT) helix that binds beside a FAD cofa

72 ulin, or whether proteolytic cleavage of the C-terminal tail (CTT) of alpha- and beta-tubulin, the lo

73 Here, we provide evidence that the C-terminal tail (CTT) of eIF1A, which we previously impl

74 vation of arginine relative to lysine in the C-terminal tail (CTT) of HIV-1 envelope (Env).

75 by eliminating the last two residues of the C-terminal tail (CTT) of Rps16, believed to contact init

76 Mutations in the C-terminal tail decrease fusion activity in vitro, but n

77 The C-terminal tails demonstrate more rapid deuterium exchan

78 by tethering multiple Stim1 domains to Orai1 C-terminal tail, demonstrating that alpha-SNAP regulates

79 es clustered in two separable regions of the C-terminal tail, designated cluster 1 (Thr(347), Thr(349

80 This C-terminal tail displays the binding site for partner pr

81 erize the function of the EBV gB cytoplasmic C-terminal tail domain (CTD) in fusion, we used a previo

82 However, when the C-terminal tail domain (CTD) is deleted, the majority of

83 n our current studies, we characterized a gB C-terminal tail domain (CTD) mutant truncated at amino a

84 Here we have examined the role of the C-terminal tail domain of Cin8 in regulating directional

85 Furthermore, the C-terminal tail domain of keratin 8 is shown to be essen

86 on-catalytic domain of separase binds to the C-terminal tail domain of three homologs of the centrome

87 onsists of an N-terminal 'head' domain and a C-terminal tail domain that contains several predicted c

88 metavinculin-specific insert is part of the C-terminal tail domain, the actin-binding site of both i

89 core domain and an intrinsically disordered C-terminal tail domain.

90 rostatic in nature and depends on the acidic C-terminal tail (E-hook) of tubulin.

91 The intrinsically disordered eIF1A C-terminal tail (eIF1A-CTT) binds to eIF5B Domain-4 (eIF

92 ), while the other two selectively truncated C-terminal tails encoded by either exon 4 (mE4M mice) or

93 yers with its flexible N-terminal domain and C-terminal tail exposed to the outside.

94 runcated ACTN4 mutant 1-890, which lacks the C-terminal tail, fails to rescue the amoeboidal morpholo

95 nal propeller needs to be able to engage the C-terminal tail for vesicle clustering to occur.

96 in B-stimulated neutrophils produce multiple C-terminal tail FPR1 Ser/Thr phosphorylations but have l

97 f FPR1 phosphorylation can be monitored with C-terminal tail FPR1-phosphospecific antibodies.

98 with the N-terminal domain of Nup82 and the C-terminal tail fragment of Nup159.

99 decoupled, with the intrinsically disordered C-terminal tail fragment of ODC being required only for

100 that WASP displaces the autoinhibitory Arp3 C-terminal tail from a hydrophobic groove at Arp3's barb

101 this additional negative charge prevents the C-terminal tail from interacting with the substrate and

102 nding at this unique site shields the S100A9 C-terminal tail from proteolytic degradation by proteina

103 on event within the last few residues of the C-terminal tail generates a posttranslational modificati

104 intermolecular NTD-CTD interactions, and the C-terminal tail, have substantial static or dynamical di

105 the anionic semiquinone (ASQ) restructures a C-terminal tail helix (CTT) that otherwise inhibits inte

106 phosphorylated on Yck consensus sites in its C-terminal tail in a Yck-dependent manner and that this

107 olved the high-resolution structure of DISC1 C-terminal tail in complex with its binding domain of Nd

108 plained by the lack of an acidic, disordered C-terminal tail in human mtSSB protein.

109 tation of nanoscale motion at the tip of the C-terminal tail in the phosphomimic S339D/S340D mutant.

110 ersely, the interaction of RecQ with the SSB C-terminal tail increases the on-rate of RecQ-DNA bindin

111 Here we demonstrate that the Arp3 C-terminal tail is a structural switch that prevents Arp

112 able lipid bilayers, the requirement for the C-terminal tail is abrogated.

113 We show that the TubZ C-terminal tail is an unstructured domain that fulfills

114 The function of the C-terminal tail is conserved in human Atlastin.

115 Their C-terminal tail is especially important in enabling the

116 ic resonance spectroscopy establish that the C-terminal tail is essential for high-affinity Mn(II) co

117 protein S/TFPI interaction and that the TFPI C-terminal tail is not essential for this enhancement.

118 It contains nine tyrosines in its C-terminal tail, many of which are phosphorylated and bi

119 activity compared with ADAMTS13 lacking its C-terminal tail (MDTCS) or its CUB1-2 domains (WTDeltaCU

120 ed a threonine phosphorylation site within a C-terminal tail motif, which is targeted by the Akt/seru

121 The C-terminal tail of a second ubiquitin molecule is locate

122 mplex module for PM association found in the C-terminal tail of AAPs.

123 The C-terminal tail of AE1 has an important role in its pola

124 hat the RXR-type dibasic motif in the distal C-terminal tail of an HIV coreceptor GPR15 negatively re

125 We find that the C-terminal tail of Asf1 enhances the interaction of Asf1

126 In addition, we show that the C-terminal tail of Asf1 is phosphorylated at T270 in yea

127 In particular, the role of the amphipathic C-terminal tail of Atlastin is still unknown.

128 These data suggest that the C-terminal tail of Atlastin locally destabilizes bilayer

129 Although the C-terminal tail of beta' is dispensable for cofactor for

130 ion occurs when the intrinsically disordered C-terminal tail of beta-spectrin binds the N-terminal ta

131 Kindlin-2 linkage to the C-terminal tail of beta3 completed the outside-in circui

132 Thus, the dissociation of BiP from the C-terminal tail of bZIP28 is a major switch that activat

133 BiP binding sites in the C-terminal tail of bZIP28 were identified in a phage dis

134 ons from random-coil chemical shifts for the C-terminal tail of capsid and SP1, both in the absence a

135 lectrostatic interactions between the acidic C-terminal tail of Cdc34 and a feature on SCF called the

136 quently, the induced folding of the flexible C-terminal tail of CP12 in the active site of GAPDH stab

137 efore, these data suggest a new role for the C-terminal tail of CRY1 in which phosphorylation rhythmi

138 Furthermore, we show that, in human, the C-terminal tail of CSN1, a segment not included in our c

139 nesis revealed that a conserved motif in the C-terminal tail of DC2 is critical for assembly into the

140 H2)-SH3-SH2 domains, which interact with the C-terminal tail of DCC, is sufficient to restore netrin-

141 are consistent with the hypothesis that the C-terminal tail of Drs2p is auto-inhibitory to Drs2p act

142 her these results suggest that, although the C-terminal tail of dSLBP does not contact the RNA, phosp

143 the process by showing that the cytoplasmic C-terminal tail of EBV BILF1 is required for reducing su

144 mutations reduce autophosphorylation of the C-terminal tail of EGFR and attenuate phosphorylation of

145 IF1A promote scanning, eIF1 and possibly the C-terminal tail of eIF1A must be displaced from the P de

146 uencing revealed a partial truncation in the C-terminal tail of Env that had emerged in the sort; how

147 , highlighting the indispensable role of the C-terminal tail of FAAP20, beyond the compact zinc finge

148 concert with structural elements within the C-terminal tail of FFA4 to allow for the recruitment of

149 e cargo-binding domain was identified in the C-terminal tail of fungal Kinesin heavy chain (KHC).

150 WL), which is located within the cytoplasmic C-terminal tail of GluN3A and mediates its binding to th

151 In addition, Gbetagamma interacts with the C-terminal tail of GPR124 and promotes the formation of

152 he nucleic acid binding site of BolA and the C-terminal tail of Grx.

153 Two short regions in the C-terminal tail of H1 and the C-terminal tail of one of

154 The C-terminal tail of H1.2 is critical for the observed eff

155 WP2A does not influence H2A.Z occupancy, the C-terminal tail of H2A.Z is one important mediator to re

156 hemical approaches, we demonstrated that the C-terminal tail of HER3 interacted with the WW domains o

157 The C-terminal tail of hPC2 contains 2 EF hand motifs, but o

158 Rather, the flexible C-terminal tail of Hsp16.5 changes its orientation relat

159 IRS-1 mediates a direct interaction with the C-terminal tail of IQGAP1.

160 omer contains a lid motif that can clamp the C-terminal tail of its dimeric binding partner against i

161 show that SEPT9 associates directly with the C-terminal tail of KIF17 and interacts preferentially wi

162 Kif5B (kinesin-1) motor domain fused to the C-terminal tail of Kif18A.

163 The C-terminal tail of Lc is not visible in any of the curre

164 te with Lck in cells and dephosphorylate the C-terminal tail of Lck, which prevents its adoption of a

165 ed by hyperphosphorylation of the inhibitory C-terminal tail of Lck.

166 A lysine residue (Lys(1112)) at the C-terminal tail of mGluR1 (a member of the group I mGluR

167 etimes required two specific leucines on the C-terminal tail of microR.

168 etween the C-terminal domain of BRD4 and the C-terminal tail of MLV IN.

169 In sum, these observations suggest that the C-terminal tail of MoaA provides an essential mechanism

170 A phosphorylation cluster in the C-terminal tail of MOPr was identified as a mediator of

171 We then identified serine 588 in the C-terminal tail of mouse CRY1 as a potential DNA-PK phos

172 nd when the human tail is substituted by the C-terminal tail of murine S100A9.

173 studies on Naa60 were unable to resolve the C-terminal tail of Naa60, which is responsible for the o

174 Arg-395 stabilizes the C-terminal tail of NCF4 and the conformation of NCF2 loo

175 hobic sequence within the loosely structured C-terminal tail of Ndc10.

176 we identified a critical RXG sequence in the C-terminal tail of NgBR that is conserved and essential

177 We show that the C-terminal tail of NuMA can directly bind to the C termi

178 and the dimers are further connected by the C-terminal tail of one GRASP domain inserting into the b

179 regions in the C-terminal tail of H1 and the C-terminal tail of one of the two H2A histones are also

180 r this Golgi retention was also found in the C-terminal tail of P/rds and supported the cilia targeti

181 The regions in the C-terminal tail of P/rds are essential for this unconven

182 tein/protein docking, we discovered that the C-terminal tail of p47(phox) is critical for stabilizing

183 purified caspase-3 and -8 could release the C-terminal tail of p53R2.

184 t that this interaction involves the dynamic C-terminal tail of P7, more specifically an acidic clust

185 es within the adenosine-binding motif in the C-terminal tail of PKAc within a cluster of acidic amino

186 at this peptide is a mimic for the conserved C-terminal tail of PP2A, an important region of the phos

187 and site-specific phospho-Ser/Thr(s) in the C-terminal tail of PTEN.

188 with a portion of the natively unstructured C-terminal tail of RhlB at 2.8-A resolution, and in comp

189 sis revealed that the OB-fold domain and the C-terminal tail of Rim1 are both involved in interaction

190 , and proteolytic cleavage or removal of the C-terminal tail of SAA resulted in formation of various-

191 However, when the entire C-terminal tail of SALM1 was deleted, SALM1 was detected

192 The C-terminal tail of SERCA2b consists of an 11th transmemb

193 nds on MsRecO interaction with the conserved C-terminal tail of single-stranded (ss) DNA-binding prot

194 Based on our results, we propose that the C-terminal tail of SLN is a distinct, essential domain i

195 ionally characterized alanine mutants of the C-terminal tail of SLN using co-reconstituted proteolipo

196 ction between the tmRNA-binding core and the C-terminal tail of SmpB play an important role in tmRNA

197 PIPKIgammai2 directly interacted with the C-terminal tail of Src and regulated its subcellular loc

198 of naturally occurring protease sites in the C-terminal tail of SUMO proteins.

199 nt on targeting the AKAP5-PKA complex to the C-terminal tail of the beta1-AR.

200 rmed a high-affinity interaction between the C-terminal tail of the beta1a and RyR1.

201 ta1a490-524) corresponding to the 35-residue C-terminal tail of the beta1a subunit.

202 e we engineer phosphorylation sites into the C-terminal tail of the beta2-adrenoceptor (beta2AR) and

203 fied two phosphorylation sites at the distal C-terminal tail of the chemokine receptor CXCR4, but wer

204 The C-terminal tail of the Drosophila formin Cappuccino (Cap

205 The approximately 230-residue C-terminal tail of the epidermal growth factor receptor

206 RE domain directly binds to the proline-rich C-terminal tail of the essential snRNP core proteins SmN

207 c peptide (LLP2) sequence of the cytoplasmic C-terminal tail of the HIV-1 gp41 envelope protein inhib

208 ation between the 3rd intracellular loop and C-terminal tail of the human orexin OX(1) and OX(2) G pr

209 Phosphorylation of residues in the C-terminal tail of the micro-opioid receptor (MOPr) is t

210 The glycan binding site and the novel C-terminal tail of the mutant CALR proteins were require

211 that both apo-CaM and Ca(2+)/CaM bind to the C-terminal tail of the neuronal channel Kv7.4 (KCNQ4), w

212 r the interaction with arrestin-3 within the C-terminal tail of the receptor.

213 the SAM-binding site, whereas the conserved C-terminal tail of the second monomer provides residues

214 that mediates critical interactions with the C-terminal tail of the spliceosomal SmN/B/B' proteins in

215 , and this study shows that BiP binds to the C-terminal tail of the stress sensor/transducer bZIP28,

216 live cells to identify a short motif in the C-terminal tail of the TRPV1 subunit that governs channe

217 xpression of a short segment within the very C-terminal tail of TRIM56 inhibited the replication of i

218 lular integrin alphaVbeta3 binds RKRK at the C-terminal tail of tropoelastin.

219 have used this microarray to interrogate the C-terminal tails of a small group of candidate proteins

220 nd bundle MTs by interacting with the acidic C-terminal tails of beta-tubulin.

221 The C-terminal tails of beta2 are predominantly responsible

222 The C-terminal tails of CysE and CdiA-CT each insert into th

223 The conserved C-terminal tails of GroEL are thus important for protein

224 y because of the interaction with the acidic C-terminal tails of the tubulin monomers.

225 microtubule binding was not dependent on the C-terminal tails of tubulin.

226 d, a construct composed of the B box and the C-terminal tail only bent DNA at higher protein concentr

227 rsely, the overexpression of a competing CD9 C-terminal tail peptide in REH cytoplasm decreased RAC1

228 next generation sequencing, we show that the C-terminal tail peptide region of MLV IN is important fo

229 that this requires the unstructured anionic C-terminal tail peptides found on both alpha- and beta-t

230 extension of HMO1 as truncation of the HMO1 C-terminal tail phenocopies hmo1 deletion.

231 stinct mechanisms, characterized by elevated C-terminal tail phosphorylation or by covalent dimerizat

232 gion 3 (CBR3) loop, the Calpha2 loop and the C-terminal tail phosphorylation site.

233 ructural understanding of PTEN regulation by C-terminal tail phosphorylation, we used protein semisyn

234 Unexpectedly, the Cmicro4 domain and its C-terminal tail piece are responsible and sufficient for

235 p47(phox) C-terminal tail plays a key role in stabilizing intramol

236 Leu(496)-Leu(500)-Trp(503) within the beta1a C-terminal tail plays a nonessential role in the bidirec

237 311)) in the membrane-proximal region of the C-terminal tail plays a pivotal role in mediating the an

238 Structural comparison also suggests that the C-terminal tail plays a role in the enzymatic function t

239 ing in vitro enzyme assays, we show that the C-terminal tail portion of these peptides is dispensable

240 Rather, deletion of a 63-residue-long C-terminal-tail portion of TRIM56 abrogated the antivira

241 two trimer-of-dimer discs stabilized by the C-terminal tails, possibly through tail-to-tail interact

242 n-treated cardiomyocytes) displays decreased C-terminal tail priming-site phosphorylation, increased

243 inal tail and the adjacent SAM domain or the C-terminal tail proceeding the HD domain are targeted by

244 llographic structure of NV protease with the C-terminal tail redesigned to mimic P4 to P1 of another

245 nstructured segment in Nup53 and show that a C-terminal tail region binds to a putative helical fragm

246 ndependent of the presence or absence of the C-terminal tail region of CDK9, unlike the binding of th

247 merization and reveal a critical role of the C-terminal tail region of IN in higher order oligomeriza

248 on dimer formation; however deletion of the C-terminal tail region prevented dimer formation in vivo

249 ound predicted to bind to PC2 in the PC1:PC2 C-terminal tail region with helix:helix interaction.

250 ne knot (ICK) backbone region and a flexible C-terminal tail region, similar to previously described

251 We further showed that the N- and C-terminal "tail" regions of the peptide are important f

252 We propose that Cu binding to the Ctr1 C-terminal tail regulates Cu transport into the cytoplas

253 a directed orientation of the beta and beta' C-terminal tails relative to alpha within the holoenzyme

254 NV protease construct, we observed that the C-terminal tail, representing the native substrate posit

255 interaction between Ca(2+)/CaM and the Kv7.4 C-terminal tail requires only the B segment.

256 istone H3 in vivo and, further, that loss of C-terminal tail residues 211 to 279 weakens yAsf1-histon

257 Phosphorylation was detected at rhodopsin C-terminal tail residues T336 and S338.

258 mutant family where mutations in the S100A9 C-terminal tail (residues 96-114) are employed to evalua

259 nding domain, residues 1-177, and a flexible C-terminal "tail", residues 178-261.

260 , located in the Cx43 intracellular loop and C-terminal tail, respectively, act as SUMO conjugation s

261 Removing the C-terminal tail resulted in a protein that bent DNA to a

262 tween apo-CaM and the Kv7.4 tail involve two C-terminal tail segments, known as the A and B segments,

263 Truncation of most of the Drs2p C-terminal tail sequence activates its ATPase activity b

264 ow the enzyme binds the functionally crucial C-terminal tail sequence of alpha-tubulin and how this i

265 We propose a model in which the HMGB1 C-terminal tail serves as an intramolecular damper that

266 er/Thr residues (amino acids 380-385) on the C-terminal tail serves to alter the conformational state

267 utive internalization that is driven by PAR1 C-terminal tail sorting motifs and is a process that enh

268 e N-terminal 75% of apoA-I, and its flexible C-terminal tail suggest the propagation of structural pe

269 mulated the nuclear translocation of the PC1 C-terminal tail/TAZ (PC1-CTT/TAZ) complex, leading to in

270 ike JAZ8, however, JAZ13 contains a Ser-rich C-terminal tail that is a site for phosphorylation.

271 0 is specific and determined by the receptor C-terminal tail that is both necessary and sufficient fo

272 esses a unique, structurally uncharacterized C-terminal tail that plays an important role in autophos

273 o unique features as follows: the first is a C-terminal tail that stabilizes the ultimate four HEAT r

274 of the 5-HT3A subunit, but not on the P2X2R C-terminal tail that triggers the functional cross-inhib

275 dentify activities for the highly basic Rrp6 C-terminal tail that we term the 'lasso' because it bind

276 XRCC4 and XLF both include disordered C-terminal tails that are functionally dispensable in is

277 ,8-dihydroneopterin aldolase (Mt-FolB), have C-terminal tails that could also interact with Mt-Enc.

278 that Cingulin directly binds to microtubule C-terminal tails through electrostatic interactions.

279 flexible hinge that enables movement of the C-terminal tail, thus permitting proper positioning and

280 g region (EF) or two Arg residues within the C-terminal tail (TL).

281 Piasy interacts with the PITX2 C-terminal tail to attenuate its transcriptional activit

282 In contrast, Pias1 interacts with the PITX2 C-terminal tail to increase PITX2 transcriptional activi

283 osphorylation disrupts H-bonds that link the C-terminal tail to the autoinhibitory region (AIR) and t

284 FGF19 and FGF21 use their respective C-terminal tails to bind to a common binding site on bet

285 ic states and Ca(2+)-binding profiles in the C-terminal tail using biophysical approaches.

286 Evaluation of defined SmpB C-terminal tail variants highlighted the importance of e

287 ket on the RNR small subunit (RRM2) near the C-terminal tail was proposed by computer modeling and ve

288 protein, in which the tmRNA ORF or the SmpB C-terminal tail was substituted with the equivalent but

289 rther insights into the function of the SmpB C-terminal tail, we examined the tagging activity of hyb

290 vivo effects of missense mutation of DISC1's C-terminal tail, we tested mice carrying mutation D453G

291 minus to the II-III and III-IV loops and the C-terminal tail were significantly lower, thus suggestin

292 distinct structural feature, the protruding C-terminal tail, which appears in both the mutant and wi

293 lippase is subject to auto-inhibition by its C-terminal tail, which can be relieved by a phosphoinosi

294 ight polymers of FtsZ constructs lacking the C-terminal tail, which is known to provide a flexible te

295 Less is known about the Ku70 C-terminal tail, which lies outside the ring.

296 domain binds to the CK2-phosphorylated XRCC4 C-terminal tail, while LigIV uses its tandem BRCT repeat

297 erves a peptide-in-groove interaction of the C-terminal tail with an adjacent beta-sandwich, thereby

298 ith G protein and through its phosphorylated C-terminal tail with beta-arrestin.

299 ocalization required interactions of the LHR C-terminal tail with the PDZ protein GAIP-interacting pr

300 ggesting an interaction of exon 7-associated C-terminal tails with beta-arrestin 2 in morphine-induce