ライフサイエンスコーパス: C-type lectin

1 ave recently been shown to express Langerin (c-type lectin).

2 ized protein belonging to the superfamily of C-type lectins.

3 divalent cations, suggesting involvement of C-type lectins.

4 king mannose-dependent target cell entry via C-type lectins.

5 cium-dependent carbohydrate binding in other C-type lectins.

6 ) cells expressing macrophage galactose-type C-type lectin 1 (MGL-1), a marker of alternatively activ

7 erentially express macrophage galactose-type C-type lectin 1 (MGL1/CD301), a marker of alternatively

8 se-1 (TIMP-1), and macrophage galactose-type C-type lectin-1.

9 The human C-type lectin 18 (clec18) gene cluster, which contains t

10 with the glycoprotein VI collagen receptor, C-type lectin 2, the receptor for podoplanin, and Fc rec

11 tant, named Rosetteless, maps to a predicted C-type lectin, a class of signaling and adhesion genes r

12 demonstrated in the mouse that mAbs against C-type lectins administered intradermally are taken up b

13 ) adjacent to its ligand, activation-induced C-type lectin (AICL).

14 jacent to its ligand, ie, activation-induced C-type lectin (AICL).

15 bined DC activation via Macrophage-inducible C-type lectin and TLR7/8 representing a novel approach t

16 ysfunction causes deficiencies in intestinal C-type lectins and antimicrobial peptides, which leads t

17 that DC-SIGN microdomains may contain other C-type lectins and that the DC-SIGN cytoplasmic region i

18 ace receptors (mannose receptor-1 (MRC1) and C-type lectins), and subsequent upregulation of cytokine

19 histocompatibility complex class I (MHC-I), C-type lectins, and the mouse mammary tumor virus and he

20 Our findings identify C-type lectins as mediators of membrane attack in the mu

21 ct coregulation with different cis-regulated C-type lectins, C3 was regulated in a coexpression netwo

22 We found that the expression of the C-type lectin, CD209, known to be expressed on tissue ma

23 (-) LSCs are generally highly quiescent, the C-type lectin CD93 is expressed on a subset of actively

24 The C-type lectin chondrolectin (chodl) represents one of th

25 erved that gut DCs express mRNA encoding for C-type lectin (CLEC) 7A, CLEC9A, CLEC12A, and CLEC4N.

26 ins, cathepsins, and the natural killer (NK)/C-type lectin (CLEC) complex [6-12].

27 ry ligand binding by novel means through the C-type lectin (CLec) fold.

28 We report that the C-type lectin CLEC14A is a novel TEM.

29 We show that the group 14 C-type lectins CLEC14A, CD93 and CD248 directly bind to

30 e have described how the recently discovered C-type lectin collectin-11 (CL-11, also known as CL-K1 a

31 The detection of an EhV86-encoded C-type lectin-containing protein confirmed that infectio

32 Mvarphi, whereas blockade of CLEC5A/MDL-1, a C-type lectin critical for dengue hemorrhagic fever and

33 Dendritic cells express DC-SIGN, a C-type lectin (CTL) that binds a variety of pathogens an

34 ed an enrichment for sequences homologous to C-type lectins (CTLs), an evolutionarily ancient family

35 suppresses RIG-I and Mda5 by activating the C-type lectin DC-SIGN and inducing signaling that preven

36 The C-type lectin DC-SIGN expressed on dendritic cells (DCs)

37 The C-type lectin DC-SIGNR (dendritic cell-specific ICAM-3-g

38 Furthermore, CV-N competed with the C-type lectins DC-SIGN and mannose receptor for ligand b

39 MBL and SARS-S blocked viral binding to the C-type lectin, DC-SIGN.

40 ound DCs and colocalized specifically to the C-type lectin DCIR.

41 that targeting nanoparticles to pDCs via the C-type lectins DEC-205, DC immunoreceptor, blood DC Ag-2

42 A monoclonal antibody against the C-type lectin DEC205 (alphaDEC205) is an effective vehic

43 The C-type lectin Dectin-1 binds to yeasts and signals eithe

44 We show that another C-type lectin, Dectin-2, also signals via Syk and CARD9,

45 Here, we report that C-type lectin dendritic cell (DC) immunoreceptor (DCIR),

46 the glycosylated WNV envelope protein to the C-type lectin dendritic cell-specific intercellular adhe

47 We showed previously that the C-type lectins, dendritic cell-specific intercellular ad

48 ovel mucin-like glycoprotein that contains a C-type lectin domain (CTLD) and has orthologs in C. homi

49 active epitopes in the cysteine-rich (CysR), C-type lectin domain 1 (CTLD1), and C-type lectin domain

50 (CysR), C-type lectin domain 1 (CTLD1), and C-type lectin domain 7 (CTLD7) domains and confirmed the

51 ndent on a predicted long-loop region in the C-type lectin domain and is abrogated by mutation within

52 The C-type lectin domain containing group 14 family members

53 d exposure; p=2.3x10-7) and was annotated to C-Type Lectin Domain Family 11, Member A (CLEC11A), whic

54 C-type lectin domain family 3 member A (CLEC3A) is a poo

55 Genetic variation in or near the C-type lectin domain family 4 member M (CLEC4M) has been

56 miR-125a reduced expression of C-type lectin domain family 5, member a (Clec5a), which

57 given soluble beta-glucans, which antagonize C-type lectin domain family 7 member A (CLEC7A or DECTIN

58 ll receptor delta chain) and Clec7a (encodes C-type lectin domain family 7 member a, also known as DE

59 expression of Cre recombinase driven by the C-type lectin domain family 9, member a (Clec9a) locus c

60 t stem cell growth factor (SCGF; also called C-type lectin domain family member 11A [CLEC11A]), a hem

61 or the FcRgamma chain, and we found that the C-type lectin domain of CLECSF8 was responsible for its

62 tes, and hypertrophic chondrocytes secrete a C-type lectin domain protein, Clec11a, which promotes os

63 nces the conformational binding loops of the C-type lectin domain that mediate interactions with tena

64 f a family of secreted proteins containing a C-type lectin domain, is expressed in various organs and

65 characterized a novel Cryptosporidium parvum C-type lectin domain-containing mucin-like glycoprotein,

66 ricin, fibronectin type II, first and second C-type lectin domains (CTLD).

67 scavenger receptor cysteine-rich (SRCR) and C-type lectin domains, which function in ligand binding

68 Collectin-11, a soluble C-type lectin expressed in renal tissue, has been implic

69 n the present study, we show that DC-SIGN, a C-type lectin expressed on DCs, binds directly to C1q, a

70 we have demonstrated that mice deficient in C-type lectin family 14 member A (CLEC14A) display enhan

71 angiogenesis is regulated by shedding of the C-type lectin family 14, member A (CLEC14A) ectodomain,

72 C-type lectin family 14, member A (CLEC14A), is a single

73 RegIIIbeta is a member of the C-type lectin family called RegIII.

74 rofile was obtained by stimulating Dectin-1 (C-type lectin family member) on Rictor(-/-) DC.

75 s X, a ligand specific for DC-SIGN among the C-type lectin family.

76 ope glycoprotein E2 is a novel ligand of pDC C-type lectin immunoreceptors (CLRs), blood DC antigen 2

77 gainst a critical role for mannose-dependent C-type lectin interactions during the initial stages of

78 ith the cognate CTLR keratinocyte-associated C-type lectin (KACL) selectively expressed by human kera

79 s NKC-encoded ligand keratinocyte-associated C-type lectin (KACL).

80 e infectious synapse or the interplay of the C-type lectins, Langerin on Langerhans cells (LCs), and

81 e receptors include members of the NKRP1 and C-type lectin-like 2 (CLEC2) gene families, which consti

82 re was a preferential expansion of licensed, C-type lectin-like activating receptor Ly49H+ NK cells w

83 immunoglobulin-like receptors (KIRs) and the C-type lectin-like CD94:NKG2 receptors.

84 reas KACL forms a homodimer resembling other C-type lectin-like dimers, NKp65 is monomeric.

85 , several amino acid residues located in the C-type lectin-like domain (CTLD) and the sperm-coating p

86 It possesses a C-type lectin-like domain (CTLD) followed by a poorly ch

87 (CysR), fibronectin-like type II (FnII), and C-type lectin-like domain 1 (CTLD1) domains of PLA2R onl

88 ecently we solved a crystal structure of the C-type lectin-like domain of a homologous protein, NKR-P

89 and interpret the solution structure of the C-type lectin-like domain of NKR-P1C using chemical cros

90 The structure revealed C-type lectin-like domains (CTLDs) that occur as dimers

91 ectin II domains were folded back to contact C-type lectin-like domains 1-6, and a "tail" comprising

92 in-like domains 1-6, and a "tail" comprising C-type lectin-like domains 7-8.

93 d raises the possibility that a protein with C-type lectin-like domains regulated development in the

94 ar localization of AICL is determined by its C-type lectin-like ectodomain.

95 s (Nkrp1, NKRP1A, NKp80, NKp65) instead bind C-type lectin-like ligands to which they are genetically

96 ort the first characterization of the orphan C-type lectin-like molecule Clr-a encoded by the Clec2e

97 Human C-type lectin-like molecule-1 (CLL1) is a recently ident

98 onredundant function of these highly related C-type lectin-like molecules in the context of intestina

99 also involves NK gene complex (NKC)-encoded C-type lectin-like molecules such as NKG2D and Nkrp1 rec

100 Interactions between C-type lectin-like NK cell receptors and their protein l

101 Convulxin (CVX) is a C-type lectin-like protein from the venom of the South A

102 AM)-coupled receptors glycoprotein (GP)VI or C-type lectin-like receptor (CLEC)-2 is associated with

103 NKp65 is an activating human C-type lectin-like receptor (CTLR) triggering cellular c

104 The C-type lectin-like receptor 2 (CLEC-2) activates platele

105 C-type lectin-like receptor 2 (CLEC-2) is a platelet rec

106 C-type lectin-like receptor 2 (CLEC-2) is an essential p

107 Platelet C-type lectin-like receptor 2 (CLEC-2) is known to maint

108 ng mouse development, binding of Pdpn to the C-type lectin-like receptor 2 (CLEC-2) on platelets is c

109 ing with lymphatic endothelial cells through C-type lectin-like receptor 2 (CLEC-2) receptors.

110 eptor glycoprotein (GP)VI-FcRgamma chain and C-type lectin-like receptor 2 (CLEC-2)-mediated platelet

111 llagen receptor glycoprotein (GP) VI and the C-type lectin-like receptor 2 (CLEC-2).

112 nd proplatelet formation by interaction with C-type lectin-like receptor 2 (CLEC-2).

113 nctions as an activating ligand for platelet C-type lectin-like receptor 2 (CLEC-2, also known as CLE

114 ycoprotein VI (GPVI) and podoplanin receptor C-type lectin-like receptor 2 (CLEC2) are receptors impl

115 deficient for the platelet-specific receptor C-type lectin-like receptor 2 (CLEC2) as blood backfills

116 Glycoprotein VI and C-type lectin-like receptor 2 are essential platelet act

117 ost completely inhibited glycoprotein VI and C-type lectin-like receptor 2 signaling.

118 ompound specifically inhibited collagen- and C-type lectin-like receptor 2-induced human platelet agg

119 elective and essential role in collagen- and C-type lectin-like receptor 2-mediated platelet activati

120 he collagen receptor glycoprotein VI and the C-type lectin-like receptor 2.

121 n through the collagen receptor GPVI and the C-type lectin-like receptor 2.

122 CD141(+) DC in humanized mice express C-type lectin-like receptor 9A, XCR1, CADM1, and TLR3 bu

123 ng injection of Abs against human DEC-205 or C-type lectin-like receptor 9A.

124 NKp80 is a C-type lectin-like receptor broadly expressed on human n

125 The C-type lectin-like receptor CD161, which has recently be

126 The C-type lectin-like receptor CLEC-2 mediates platelet act

127 Among these is the C-type lectin-like receptor NKp80 which is encoded in th

128 The mouse C-type lectin-like receptor Nkrp1g was previously shown

129 Ly49Q, a C-type lectin-like receptor specific for MHC-I, possesse

130 previously described the cloning of a novel C-type lectin-like receptor, KLRH1, encoded in the NK co

131 rs thrombosis within vessels via ligation of C-type lectin-like receptor-2 (CLEC-2) on platelets by p

132 he following receptors: glycoprotein (GP)VI, C-type lectin-like receptor-2 (CLEC-2)>GPIb>alpha6beta1,

133 Rhodocytin, an agonist of the C-type lectin-like receptor-2 (CLEC-2), elicits powerful

134 killer gene complex-encoded immunomodulatory C-type lectin-like receptors include members of the NKRP

135 ler (NK) gene complex (NKC) encodes numerous C-type lectin-like receptors that govern the activity of

136 us pathogen recognition receptors, including C-type lectin-like receptors, TLRs, and nucleotide oligo

137 itutive or platelet-specific deletion of the C-type-lectin-like receptor (CLEC-2) exhibit hemorrhagin

138 he podoplanin and collagen/fibrin receptors, C-type-lectin-like-2 (CLEC-2) and glycoprotein VI (GPVI)

139 The C-type lectin macrophage galactose-type lectin (MGL) exe

140 s were used that have high expression of the C-type lectin mannose receptor (MR; CD206).

141 uited interstitial macrophage galactose-type C-type lectin (MGL)1(+)/CD11c(-) and crown-like structur

142 Identification of the C-type lectin Mincle as one of the receptors underlying

143 We previously identified the C-type lectin Mincle as receptor for these glycolipids t

144 The role of macrophage-inducible C-type lectin Mincle in lung innate immunity against myc

145 reover, M. bovis BCG-induced upregulation of C-type lectin Mincle on professional phagocytes critical

146 C-type lectin receptors macrophage-inducible C-type lectin (Mincle) and Mcl to activate macrophages.

147 her, our results reveal a pathway by which a C-type lectin modulates the equilibrium between infectio

148 rfactant Protein D (SP-D) is an oligomerized C-type lectin molecule with immunomodulatory properties

149 , including genome-wide significance for the C-type lectin molecules CLEC4F-CD207 at 2p13.3 and CLEC4

150 We now show that an Aedes aegypti C-type lectin, mosGCTL-1, is induced by WNV, interacts w

151 at the gut microbiome in mosquitoes utilizes C-type lectins (mosGCTLs) to evade the bactericidal capa

152 ycystic kidney disease (PKD) domain, and the C-type lectin motif, while the larger one is the C-termi

153 pothesized that langerin, the distinguishing C-type lectin of Langerhans cells, would recognize the h

154 e we investigated whether sCD93, a group XIV c-type lectin of the endosialin family, plays a role in

155 Here, we have characterized a C-type lectin of the NK cell receptor group that we name

156 C-type lectins of the RegIII family are bactericidal pro

157 As in many other C-type lectins, oligomerization is required for high aff

158 Langerin, a C-type lectin on Langerhans cells, mediates carbohydrate

159 Dectin-2, a C-type lectin on macrophages and other cells of the inna

160 -based activation motifs (hemITAMs) found in C-type lectin pattern recognition receptors.

161 Selectins, a family of C-type lectins, play a key role in inflammatory diseases

162 Surfactant protein A (SP-A), a C-type lectin, plays an important role in innate lung ho

163 Langerin is a C-type lectin present on Langerhans cells that mediates

164 The discovery that proteins called c-type lectins promote bone growth could lead to new tre

165 ed N-glycans that support recognition by the C-type lectin receptor (CLR) DC-specific intercellular a

166 Members of the C-type lectin receptor (CLR) family stand out among the

167 acteria, trehalose dimycolate, activates the C-type lectin receptor (CLR) Mincle.

168 Fungal infection stimulates the canonical C-type lectin receptor (CLR) signaling pathway via activ

169 The interaction of C-type lectin receptor 2 (CLEC-2) on platelets with Podo

170 TLRA/C-type lectin receptor agonist combinations were screene

171 ited that distinct combinations of TLRAs and C-type lectin receptor agonists may enhance Th1 response

172 CD302 as the simplest, single domain, type I C-type lectin receptor and showed it was expressed mainl

173 eviously unrecognized link between a myeloid C-type lectin receptor and Th2 immunity.

174 The C-type lectin receptor blood dendritic cell Ag 2 (BDCA2)

175 display an 18-fold higher expression of the C-type lectin receptor CD209a, a murine homolog of human

176 Here, we show that the C-type lectin receptor CD69 controls tTreg cell developm

177 The C-type lectin receptor CLEC-2 activates platelets throug

178 The C-type lectin receptor CLEC-2 signals through a pathway

179 Among the genes most upregulated in pDC were C-type lectin receptor CLEC4E, IL-1Rs (IL-1R1 and -2), p

180 Here, we have identified the C-type lectin receptor CLECSF8 (CLEC4D, MCL) as a key mo

181 its 67-kDa Mfa1 (minor) fimbria, targets the C-type lectin receptor DC-SIGN for invasion and persiste

182 cells (DCs), including cells expressing the C-type lectin receptor DC-SIGN, persisted at sites of HS

183 dependent antibodies 2G12 and PGT123, or the C-type lectin receptor DC-SIGN.

184 uman dendritic cells (DCs) via targeting the C-type lectin receptor DC-specific intercellular adhesio

185 Here, we found that the FcRgamma-coupled C-type lectin receptor DCAR (dendritic cell immunoactiva

186 dendritic cells (DCs) and macrophages via a C-type lectin receptor dectin-1 pathway.

187 The Syk-coupled C-type lectin receptor Dectin-1 was the first non-Toll l

188 The myeloid C-type lectin receptor Dectin-2 directs the generation o

189 a-mannan (Mn), an Mn (sugar) polymer, by the C-type lectin receptor Dectin-2 on host macrophages lead

190 t of opsonization but appears to require the C-type lectin receptor Dectin-3, a receptor not previous

191 hesion molecule-3-grabbing nonintegrin) is a C-type lectin receptor expressed on macrophages and dend

192 DDCs; furthermore, common unique patterns of C-type lectin receptor expression were identified betwee

193 n monocytes, macrophages, and DC; determined C-type lectin receptor expression; and tested the contri

194 nt have been the parallel discoveries in the C-type lectin receptor family and the Th effector arms o

195 es are known to interact with members of the C-type lectin receptor family of pattern recognition pro

196 Many members of the C-type lectin receptor family serve as pattern recogniti

197 ses are primarily mediated by members of the C-type lectin receptor family.

198 cription profile of all KIR family genes and C-type lectin receptor genes using RNA sequencing on NKT

199 CLEC9A is a recently discovered C-type lectin receptor involved in sensing necrotic cell

200 rbohydrate recognition domain of Langerin, a C-type lectin receptor involved in the host defense agai

201 of the human and murine forms of the myeloid C-type lectin receptor langerin for simple and complex l

202 Langerhans cells (eLCs) uniquely express the C-type lectin receptor langerin in addition to the HIV e

203 d mucosal Langerhans cells (LCs) express the C-type lectin receptor langerin that functions as a patt

204 that neutrophils elicited in the presence of C-type lectin receptor ligands have an increased ability

205 cture Lewis(X) (Le(X)) re-directs OVA to the C-type lectin receptor MGL1.

206 ined a previously uninvestigated role of the C-type lectin receptor Mincle in pneumonic sepsis caused

207 id trehalose dimycolate (cord factor) by the C-type lectin receptor mincle partially explains this CA

208 selectively recognized by Mincle (Clec4e), a C-type lectin receptor of the innate immune system that

209 We sought to analyze C-type lectin receptor pathways as an alternative or a c

210 is report, we demonstrate that expression of C-type lectin receptor scavenger receptor-AI (SR-AI) is

211 results illustrate the complexity of myeloid C-type lectin receptor signaling, and how an activating

212 DNGR-1 is a C-type lectin receptor that binds F-actin exposed by dyi

213 Dectin-1 (Clec7a) is a paradigmatic C-type lectin receptor that binds Syk through a hemITAM

214 Mincle is a C-type lectin receptor that is critical in the immune re

215 ection occurs upon engagement of Dectin-1, a C-type lectin receptor that signals via spleen tyrosine

216 Thus, CLEC9A functions as a SYK-coupled C-type lectin receptor to mediate sensing of necrosis by

217 Clec9a (C-type lectin receptor) or DNGR-1 (dendritic cell NK lec

218 aration during development by activating the C-type lectin receptor, CLEC-2, on platelets.

219 Here, we identified functions of one C-type lectin receptor, CLEC12A, in facilitating DC bind

220 We investigated the role of the C-type lectin receptor, CLEC5A, in macrophage activation

221 study, we demonstrated that activation of a C-type lectin receptor, dectin-1, in MDSC differentially

222 This notably depends on the C-type lectin receptor, langerin or DC-SIGN, involved in

223 Dual activation of newborn DCs via the C-type lectin receptor, macrophage-inducible C-type lect

224 we examined the mechanism by which Mincle, a C-type lectin receptor, regulates NET formation.

225 We propose that a C-type lectin receptor, SIGNR-1 (also called Cd209b), he

226 nificantly higher induction of CD23, a novel C-type lectin receptor, through NFATc1-mediated regulati

227 Although C-type lectin receptor- and Toll-like receptor-induced s

228 but not spores and depends upon Dectin-1, a C-type lectin receptor.

229 C-type lectin receptors (CLRs) are essential in shaping

230 C-type lectin receptors (CLRs) comprise a heterogeneous

231 Several spleen tyrosine kinase-coupled C-type lectin receptors (CLRs) have emerged as important

232 However, the role of TRAF6 and TAK1 in C-type lectin receptors (CLRs) in response to fungal inf

233 C-type lectin receptors (CLRs) represent a family of pat

234 C-type lectin receptors (CLRs) such as Dectin-2 function

235 with pattern recognition receptors, such as C-type lectin receptors (CLRs), on dendritic cells (DCs)

236 C-type lectin receptors (CLRs), the carbohydrate-recogni

237 attern recognition receptors (PRRs) known as C-type lectin receptors (CLRs).

238 terial toll-like receptors (TLRs) and fungal C-type lectin receptors (e.g., dectin-1).

239 nents in the signaling cascade downstream of C-type lectin receptors and as critical mediators of the

240 on receptors, including Toll-like receptors, C-type lectin receptors and NOD-like receptors.

241 (+) DCs exhibited a restricted repertoire of C-type lectin receptors and relied on CD4 for uptake of

242 cterized member of the "Dectin-2 cluster" of C-type lectin receptors and was originally thought to be

243 In this context, endocytic C-type lectin receptors are attractive targeting molecul

244 CLEC-2 is a member of new family of C-type lectin receptors characterized by a cytosolic YXX

245 Conversely, signaling via other C-type lectin receptors did not alter disease course.

246 n of DNGR-1 is replaced by that of unrelated C-type lectin receptors fail to promote cross-presentati

247 eptor (PAR)-2, Toll-like receptor (TLR), and C-type lectin receptors have been suggested to be import

248 led receptors, receptor tyrosine kinase, and C-type lectin receptors in the context of recent progres

249 g Trehalose-6,6-dibehenate (TDB) bind to the C-type lectin receptors macrophage-inducible C-type lect

250 In rodents, the C-type lectin receptors Mincle and Mcl bind TDB/TDM and

251 We have previously shown that different C-type lectin receptors on DCs play a major role in alle

252 that stochastic activation of toll-like and c-type lectin receptors on macrophages causes neuroprote

253 C-type lectin receptors play important roles in immune c

254 C-type lectin receptors sense a diversity of endogenous

255 Therein, the endocytic C-type lectin receptors serve as pattern recognition rec

256 These findings place Dectin-2 among the C-type lectin receptors that activate arachidonic acid m

257 f a number of spleen tyrosine kinase-coupled C-type lectin receptors that have been implicated not ju

258 ens to specific compartments is regulated by C-type lectin receptors that recognize glycan structures

259 leukin [IL]-10, IL-1RA, CD163, scavenger and C-type lectin receptors) and collagen genes, whereas the

260 t of anti-fungal innate immune signaling via C-type lectin receptors, and several immune-related diso

261 ginase activity and parasite growth involved C-type lectin receptors, because mannose injection decre

262 by interactions with CD4 and mannose-binding C-type lectin receptors, but not with the chemokine rece

263 ora and damaged epithelium via expression of C-type lectin receptors, many of which signal through th

264 se in gene expression, particularly of TLRs, C-type lectin receptors, several complement components,

265 s related to DC surface receptors (including C-type lectin receptors, TLRs, and galectins).

266 ion, skin DCs bound and internalized Env via C-type lectin receptors, whereas blood DC subsets, inclu

267 se to C. albicans infection via signals from C-type lectin receptors, which signal through the adapto

268 f mannan and, thus, likely to be mediated by C-type lectin receptors.

269 specific expression pattern was observed for C-type lectin receptors.

270 The innate pattern recognition C-type-lectin receptors (CLRs), including mannose recept

271 Dectin-1, a C-type lectin recognizing fungal and mycobacterial patho

272 gene and protein expression of bactericidal c-type lectins Reg3b and Reg3g in the small intestine.

273 rresponded to an altered ileal expression of C-type lectins Reg3gamma and Reg3beta, and of interleuki

274 ithelial antimicrobial response, such as the C-type lectins Reg3gamma and Reg3beta.

275 s that include induction of the bactericidal C-type lectin RegIIIgamma.

276 ucture for the extracellular domain of mouse C-type lectin related (Clr) protein g, a ligand for the

277 l function upon interaction with its cognate C-type lectin-related ligand, Clr-b.

278 a2beta1 integrin-blocking members within the C-type lectin-related protein family is less strict than

279 receptor protein-1B (NKR-P1B) and its ligand C-type lectin-related-b (Clr-b).

280 Antibodies to DC-SIGN, a c-type lectin selectively expressed by macrophages but n

281 that these sialylated Fcs require a specific C-type lectin, SIGN-R1, (specific ICAM-3 grabbing non-in

282 For example, cross-talk of TLR and C-type lectin signaling effectively shapes distinct gene

283 NCK2187 and its purified SlpA bind to the C-type lectin SIGNR3 to exert regulatory signals that re

284 eceptor with a collagenous structure and the C-type lectin specific intracellular adhesion molecule-g

285 Langerin, a trimeric C-type lectin specifically expressed in Langerhans cells

286 ruses in several families can be mediated by C-type lectins such as DC-SIGN.

287 he vitamin D nuclear receptor (VDR); soluble C-type lectins, such as surfactant protein-A (SP-A), SP-

288 macrophage galactose-type lectin (MGL) is a C-type lectin that binds to glycoproteins expressing ter

289 Reg3gamma is an antimicrobial C-type lectin that is induced by STAT3 signaling in resp

290 es the expression of RegIIIgamma, a secreted C-type lectin that kills gram-positive bacteria, includi

291 egIIIgamma (also known as Reg3g), a secreted C-type lectin that kills Gram-positive bacteria, includi

292 hese results indicate that CpClec is a novel C-type lectin that mediates C. parvum attachment and inf

293 RegIII proteins are secreted C-type lectins that kill Gram-positive bacteria and play

294 ive peptidases, 9 peptidase inhibitors and 7 C-type lectins that may function in interactions with in

295 -dependent carbohydrate recognition in other C-type lectins, the unusual location and calcium-indepen

296 x glycans that enables it to bind to certain C-type lectins, thereby enhancing its attachment to targ

297 mannosylated surface structures and exploits C-type lectins to gain cell access.

298 o known as DNGR-1), a recently-characterized C-type lectin, to recognize a preformed signal that is e

299 C-type lectin receptor, macrophage-inducible C-type lectin (trehalose-6,6-dibehenate), and TLR7/8 (R8

300 eration of selected bacteria by culture, and C-type lectins were assessed in ileal tissues by reverse