ライフサイエンスコーパス: C. botulinum

1 C. botulinum A(B) strains were identified in California

2 C. botulinum C3 exoenzyme, a pharmacologic agent that sp

3 C. botulinum type B PFGE patterns from the infant and fr

4 C. botulinum was present up to 15000 MPN per gram dried

5 A collection of 174 C. botulinum strains was examined by amplified fragment

6 s Spo0A response regulator domain fused to a C. botulinum DNA-binding domain was capable of restoring

7 Type A C. botulinum secretes the neurotoxin along with 5 other

8 cific binding domain and replacing it with a C. botulinum neurotoxin binding domain.

9 , the inflamed small bowel was resected, and C. botulinum disappeared from the stool.

10 forming microorganisms such as B. anthracis, C. botulinum, and B. cereus, which can to be used for me

11 to neutralize the toxicity of known bivalent C. botulinum strains Ab, Ba, Af, and Bf also failed to n

12 /g dried algae) showed that Cladophora-borne C. botulinum were toxin-producing species (BoNT/E).

13 for the isolation and identification of both C. botulinum and C. tetani demonstrates a sensitivity an

14 Partial inactivation by C. botulinum toxin of the small GTP-binding protein Rho

15 xins, BoNT/A2, /F4, and /F5, are produced by C. botulinum Af84.

16 relative to Bacillus subtilis but the cloned C. botulinum Spo0A was unable to complement a spo0A muta

17 These clades constituted an endemic C. botulinum population that produced the entire clinica

18 IBCA10-7060 is the first C. botulinum type Bh strain to be identified.

19 unction with previously described assays for C. botulinum neurotoxin types A, B, and E (BoNTA, -B, an

20 icate that Cladophora provides a habitat for C. botulinum, warranting additional studies to better un

21 s previously described in the literature for C. botulinum Group I type A1 into a population dynamics

22 n orphan nine-gene cluster was identified in C. botulinum and the related foodborne pathogen Clostrid

23 cheme for modelling neurotoxin production in C. botulinum Group I type A1, based on the integration o

24 med using a variety of techniques, including C. botulinum culture phenotypic properties, neurotoxin c

25 infant botulism identified the fourth known C. botulinum strain that produces both type B and type F

26 Moreover, C. botulinum was present as vegetative cells rather than

27 es seven antigenically distinct neurotoxins [C. botulinum neurotoxins (BoNTs) A-G] sharing a signific

28 o proteolytic strains assigned to group 1 of C. botulinum.

29 The abundance of C. botulinum in algal mats was quantified and the type o

30 warnings to the industry about the danger of C. botulinum and the importance of compliance with canne

31 t of Cladophora containing high densities of C. botulinum (>1000 MPN/g dried algae) showed that Clado

32 novel insights into the genetic diversity of C. botulinum and the clinical spectrum, occurrence, and

33 firm that the function of the H(C) domain of C. botulinum neurotoxin type A is limited to binding to

34 crystal structure of the catalytic domain of C. botulinum neurotoxin type E has been determined to 2.

35 Co-expression of C. botulinum C3 toxin and a COOH-terminal fragment of Ga

36 L.) is a potential habitat for the growth of C. botulinum.

37 An orphan sensor histidine kinase of C. botulinum appeared to normally phosphorylate C. botul

38 Currently, mathematical models of C. botulinum growth and toxigenesis are largely aimed at

39 is was lethal, suggesting phosphorylation of C. botulinum Spo0A repressed essential growth genes as a

40 h conservation of the amino acid sequence of C. botulinum Spo0A, some of these interactions have been

41 This revealed that 47% of a set of C. botulinum proteins were evolutionary related with Hom

42 is study were to characterize the strains of C. botulinum associated with the botulism case.

43 or different wild type and mutant strains of C. botulinum Group I type A1.

44 Strains of C. botulinum were isolated from the baby's feces and fro

45 botulinum appeared to normally phosphorylate C. botulinum Spo0A and expression of this kinase in comb

46 Our findings further establish that C. botulinum IBCA10-7060 produces novel BoNT/H.

47 in size and protein content depending on the C. botulinum strain.

48 une response with neutralizing antibodies to C. botulinum at week 19 was positive; these antibodies r

49 irst reported case of infant botulism due to C. botulinum type Af worldwide.

50 report the first infant botulism case due to C. botulinum type E worldwide.

51 xpression of this kinase in combination with C. botulinum Spo0A in B. subtilis was lethal, suggesting

52 using to filter the implicated pruno yielded C. botulinum type A.