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1 C. africana was rapidly and reliably identified by micro
2 C. sativa threshing residues were biorefined by consecut
3 absorbed radiation dose from whole-body (11)C-nicotine PET imaging of 11 healthy (5 male and 6 femal
4 uction in mGluR5 availability (that is, [(11)C]ABP688 binding) in both MDD and control subjects (aver
5 centration leading to a 50% reduction of (11)C-BMT-136088 specific binding were 73 +/- 30 nmol/kg and
6 udy assessed the in vivo distribution of (11)C-nicotine and the absorbed radiation dose from whole-bo
10 we investigate whether changes of (13)C/(12)C, (2)H/(1)H, and (15)N/(14)N ratios of NDMA give rise t
12 g pairs exhibited significantly greater (13) C transfer to recipient roots in two of four Douglas-fir
15 ydroqui noline is reported, the (1)H and (13)C NMR data of which are in excellent agreement with thos
17 f CO2 in air of known but differing delta(13)C and delta(18)O isotopic composition allows standard un
19 o reassessment of the role that the delta(13)C record plays in reconstructing the oxygenation of eart
20 mits, the carbonate carbon isotope (delta(13)C) record becomes insensitive to changes in organic carb
21 ch (LambdaC-H = Deltadelta(2)H/Deltadelta(13)C approximately epsilonbulk(H)/epsilonbulk(C), where Del
22 k(C), where Deltadelta(2)H and Deltadelta(13)C are changes in isotope ratios during degradation) resu
23 n enhancement using (13)C-diazomethane" ((13)C-TrEnDi), which results in the methyl esterification of
25 y differentiated from those arising from (13)C-labeled tracers, thereby allowing the enrichment of a
29 This work establishes hyperpolarized [(13)C]-Glyc as a novel agent for clinically relevant (13)C M
30 olved oxygen, high pH, and enrichment of (13)C in CO2) indicate that upwelling of cold, nutrient-rich
31 Here, we investigate whether changes of (13)C/(12)C, (2)H/(1)H, and (15)N/(14)N ratios of NDMA give
33 as a novel agent for clinically relevant (13)C MRS studies of energy metabolism and further provides
34 to as "trimethylation enhancement using (13)C-diazomethane" ((13)C-TrEnDi), which results in the met
36 ific capacity of about 130 mA h g(-1) at 35 C (fully charged within 100 s) and sustain more than 10
37 insight into the mechanistic details of hm(5)C function to be obtained, the availability of RNAs cont
40 construct triaryl(heteroaryl)methanes via a C-H functionalization in good to excellent yield, and re
41 entially lost over monovalent cations upon A.C protonation, providing experimental indication of the
43 have been engineered to catalyze abiological C-H bond amination reactions, but the yields of these re
45 riction mimetics are mainly effective across C. elegans strains, indicating species and strain-specif
46 um-magnesium and lithium-zinc amides affords C-2 or C-8 functionalized derivatives in a regioselectiv
50 erved sortase A-dependent cell wall-anchored C terminus, whereas the surface-exposed N terminus is hi
51 .9 nA/mug mL(-1), T = 1.4 nA/mug mL(-1), and C = 15.1 9 nA/mug mL(-1)), low limit of detection (G, A
52 viral replicative capacity of subtypes A and C may paradoxically contribute to their more efficient s
54 roup at day 10, the SAAs of both Adelta- and C-fibers at the "ascending" phase of microcontractions w
57 5)-10(-6)), whereas C-->G, U-->A, G-->C, and C-->A errors from purine-purine and pyrimidine-pyrimidin
60 ationships between the functional groups and C-H bonds of a substrate has been exploited to achieve m
62 proteins to test whether DAT and SERT N and C termini contribute to transporter substrate and inhibi
64 f respiratory yeasts such as P. pastoris and C. albicans, and it may have novel moonlighting function
65 ng Drosophila eye, we found that partial APC/C inactivation severely inhibits retinal differentiation
67 adult patients with AML, the response to Ara-C-containing therapy was inversely correlated with SAMHD
68 lective ortho-specific nitration of aromatic C(sp(2))-H bonds using chelation-assisted removable vici
72 s on the formation of hydrogen bonds between C-terminal residues of lentil peptides and residues of t
73 omeostasis (PHO) to TORC1 may differ between C. albicans and S. cerevisiae The converse direction of
74 us flow protocol has been developed for bond C-H activation which promotes the alpha-cyanation of sec
77 liable estimates of the total forest carbon (C) pool are lacking due to insufficient information on d
80 an emission line of singly ionized carbon ([C ii] at a wavelength of 158 micrometres) in four galaxi
81 in, we report a silver-free Pd(II)-catalyzed C(sp(3))-H arylation of saturated bicyclic and tricyclic
82 dditionally, many transition-metal-catalyzed C-H bond additions to polarized pi bonds occur within ca
83 summarizes the advancements in Pd-catalyzed C(sp(3))-H activation via various redox manifolds, inclu
84 ces of this challenge, we have characterized C. neoformans GMP synthase, the second enzyme in the gua
85 he benchmark Pt/C catalyst, the optimized Co@C-800 (carbonized at 800 degrees C) exhibited high oxyge
86 of diphenyl sulfide also showed competitive C-S bond cleavage giving phenyl sulfinic acid and ioniza
92 s compared to 0-47% degradation at 0 degrees C (1000 m), where the aromatic hydrocarbons fluoranthene
93 y exposed to cold treatment (40 d, 0 degrees C) and an additional group of CH fruits were pre-conditi
94 nd 8.5% (95% CI, 1.5%-15.0%) for a 1 degrees C increase in monthly MIT at <15, 15-64, and >/=65 years
95 The reaction in chloroform at 100 degrees C under Rh2(OAc)4 catalysis provides 4-aminopyrrole-3-ca
96 In the sediment heated up to 100 degrees C, we found unexpectedly low DOC concentrations in the p
97 PCB from phycocyanin and gave at 120 degrees C the same yield within 30min compared to 16h by the con
102 ed on a time scale of minutes at -15 degrees C in the presence of (0.4 mM) NaBAr(F)4 as compared with
103 brio infections at a threshold of 16 degrees C revealed a relative risk (RR)=1.14 (95% CI: 1.02, 1.27
104 -fried up to recommended limits (175 degrees C, 8h/day, 28h) in extra-virgin olive oil (EVOO), peanut
107 uits were pre-conditioned 48 h at 20 degrees C prior to low-temperature exposure (pre-conditioning, P
113 p process has been achieved at 1,300 degrees C/900 degrees C by using yttrium-based rare earth mangan
115 e enzyme had optimum temperaturet 35 degrees C and was relatively stable at 77 degrees C, with 59.93%
116 osition temperature of 320.16+/-0.35 degrees C, which indicated that there was good thermal stability
121 rocarbon degradation was faster at 5 degrees C (500 m) with 65-89% of each component degraded after 5
122 ing of CO2-from 1.5 degrees C to 4.5 degrees C or greater -remains largely unscathed by the onslaught
123 sponse to a doubling of CO2-from 1.5 degrees C to 4.5 degrees C or greater -remains largely unscathed
124 ce temperatures (14.5 degrees C-17.5 degrees C) and high chlorophyll-a ( approximately 11 mg m(-3)).
125 f low sea surface temperatures (14.5 degrees C-17.5 degrees C) and high chlorophyll-a ( approximately
130 on in a temperature control mode (60 degrees C/50 W) until there was approximately 80% EGM amplitude
132 reaching its highest activity at 65 degrees C and that Tfu-FNO is likely to act in vivo as an F420 r
133 d were at column temperature of 61.7 degrees C using tri-distilled water without salt, adjusted pH of
134 with lithium diisopropylamide at -70 degrees C is easy to achieve, whereas reaction with lithium-magn
136 hloromethane and acetonitrile at -78 degrees C in the presence of primary, secondary and tertiary alc
137 ptimized Co@C-800 (carbonized at 800 degrees C) exhibited high oxygen reduction reaction activity wit
142 ology parameters, color changes (h degrees , C *, DeltaE) microstructure (optical microscopy), and as
143 n vitro antifungal exposure failed to detect C. glabrata isolates with echinocandin resistance-associ
144 iSiCN nanocomposite films with the different C and Si contents are synthesized by the reactive-magnet
146 g GTPase domain, an intrinsically disordered C-terminal linker (CTL), and a C-terminal conserved pept
147 ed uptake of tau species, whereas the distal C-terminal-specific antibody (Tau46) had little effect.
150 , P = 0.07) was primarily driven by enhanced C uptake during spring (129%, P = 0.001) and fall (124%,
151 3)C approximately epsilonbulk(H)/epsilonbulk(C), where Deltadelta(2)H and Deltadelta(13)C are changes
152 ation, emphasizing the importance of the fac-C,N,S-iron(II) motif in promoting enzyme-like reactivity
153 nfecting ultraviolet [UV-C] light except for C difficile, for which bleach and UV-C were used); bleac
154 (quaternary ammonium disinfectant except for C difficile, for which bleach was used); UV (quaternary
159 on period to 48-70 h led to successive gamma-C(sp(3))-H arylation/intramolecular amidation and the co
161 Two common polymorphisms, the c. 1298A > C, of the methylene-tetrahydrofolate reductase (MTHFR) g
162 A with rates of approximately 10(-4) The A-->C, G-->A, A-->U, C-->U, G-->U, U-->C, and U-->G errors m
163 t (10(-5)-10(-6)), whereas C-->G, U-->A, G-->C, and C-->A errors from purine-purine and pyrimidine-py
164 ) The A-->C, G-->A, A-->U, C-->U, G-->U, U-->C, and U-->G errors mostly due to pyrimidine-purine mism
166 ], high-density lipoprotein cholesterol [HDL-C], low-density lipoprotein cholesterol [LDL-C], total c
169 events, particularly among HIV and hepatitis C infected people among whom cardiovascular disease risk
170 cially in individuals with chronic hepatitis C (HCV); however, the impact of nonheavy use is not clea
171 ins AP1 and AP2, are essential for hepatitis C virus (HCV) infection, but the underlying mechanism an
172 human immunodeficiency virus (HIV)/hepatitis C virus (HCV)-coinfected patients treated with interfero
174 viruses including human pathogens hepatitis C virus (HCV), Severe acute respiratory syndrome (SARS),
176 who are chronically infected with hepatitis C virus (HCV) and who do not have a sustained virologic
177 ng persons currently infected with hepatitis C virus lived >10 miles from a syringe services program.
178 pective study of 226 patients with hepatitis C virus-associated cirrhosis and CSPH who had SVR to int
179 ular basis of TAD formation, we performed Hi-C experiments on cells depleted for the Forkhead transcr
181 cells were able to sense alterations of HLA-C expression demonstrated by increased antiviral activit
183 regulated for LTA, LPS, Poly(dT), and Poly(I:C), and 12, 142, 249, and 16 genes were downregulated fo
184 regulated for LTA, LPS, Poly(dT), and Poly(I:C), respectively, with at least a 1-fold change relative
188 floral regulators that act nonredundantly in C. hirsuta, such that LFY has more obvious roles in flor
190 he maximal number of fucose substitutions in C. elegans, which in part may be due to different method
193 t and hydrophobic spacer peptide (SP) at its C-terminus early in the maturation process, which is pro
196 results suggest that S-palmitoylation of JAM-C can be potentially targeted to control cancer metastas
199 Y., Kazimirova, M., Roller, L., Jobichen, C., Swaminathan, K., Mizuguchi, J., Iwanaga, S., Nuttall
201 work, we identified the major protein kinase C substrate MARCKS (myristoylated alanine-rich C kinase
202 l cells transduced Gbetagamma-protein kinase C- and Gbetagamma-metalloproteinase/EGFR-dependent MAPK/
203 C], low-density lipoprotein cholesterol [LDL-C], total cholesterol [TC]) were studied as continuous v
205 llowed by the bronchi, endocrine glands-like C cells of the thyroid (medullary carcinoma), the parasy
207 the analogous complex with a pincer-type mer-C,N,S ligation, emphasizing the importance of the fac-C,
209 of the human and murine forms of the myeloid C-type lectin receptor langerin for simple and complex l
211 Casein kinase 2 (CK2) binds to the NHE3 C-terminus and constitutively phosphorylates a downstrea
213 eterocyclic carbene (NHC) chemistry, a novel C-N bond activation and ring-opening process is describe
214 ain associated with DSD activity and a novel C-terminal hydroxyphenylpyruvate dioxygenase-like domain
216 by low chemoselectivity for the amination of C-H bonds over competing reduction of the azide substrat
217 te tau toxicity, we screened a collection of C. elegans mutations in dopamine-related genes (n = 45)
219 due to Ndep has enhanced detrital inputs of C to soils, causing an average increase of 1.2 kgCm(-2)
220 ent and suggest that alternative splicing of C-Src in the developing vertebrate nervous system evolve
221 esium and lithium-zinc amides affords C-2 or C-8 functionalized derivatives in a regioselective fashi
225 important differences in how the Rb and p107 C-terminal domains (CTDs) associate with the coiled-coil
226 r, we propose a new approach to use Parylene C as a versatile template for patterning soft materials
227 agonist-induced activation of phospholipase C beta or with a rapamycin-inducible system in which var
229 n colocalize with VERNALIZATION1/PHYTOCHROME C and VERNALIZATION2, loci identified as flowering regul
231 no acid substitution mutations within a PMS2 C-terminal (721)QRLIAP motif attenuate or abolish human
232 ted that alpha-1 antitrypsin (AAT; Prolastin-C), a serine protease inhibitor used for the treatment o
233 glycoprotein called the prion protein or PrP(C) The current work tests a new hypothesis that sialylat
235 ty for the oxygen reduction reaction than Pt/C, and twice the mass activity of the hollow nanoframe.
237 ), classifying only 3.7% as "frail." The RAI-C and RAI-A represent effective tools for measuring frai
238 e insulin receptor (IR) and mannose receptor C-type 1 (MR), which functions to clear endogenous manno
239 enic zebrafish that uses a mannose receptor, C type 1 (mrc1a) promoter to drive strong EGFP expressio
240 substrate MARCKS (myristoylated alanine-rich C kinase substrate) as a potential target molecule for k
242 05]; effect size, 0.21), mean (SD) total SAC-C score (boys, 23.9 [3.9] vs girls, 24.9 [3.5]; mean dif
243 has been exploited to achieve meta-selective C-H activation by using a covalently attached, U-shaped
244 istent with predictions of conventional soil C models and suggest that elevated CO2 might increase tu
247 By expressing the target protein with SpyTag C-terminal to the SrtA recognition motif, it can be cova
248 rmediary steps as well as direct, late stage C-7 hydroxylation provides both natural products in six
250 C-B downregulation function in HIV-1 subtype C and show that carriage of Nef variants with enhanced M
254 ute HCV in HIV-1 infected individuals (SWIFT-C) is an open-label, 2-cohort clinical trial in which th
255 immune reconstitution inflammatory syndrome (C-IRIS), upon initiation of antiretroviral therapy (ART)
256 imit of detection (G, A = 0.5 mug mL(-1); T, C = 1.0 mug mL(-1)), and high selectivity in the presenc
257 [from 10microM to 50nM] in comparison to ta-C thin film electrodes and (ii) the coating method signi
262 ns harvests lipids from macrophages, and the C. neoformans-macrophage interaction is modulated by exo
265 show that a unique, conserved domain at the C-terminus of Swc5, called Bucentaur (BCNT), is essentia
266 ecies, MAF1L and MAF1S, are regulated by the C-box YSY motif, which, when mutated, alters species sto
268 ) permits positively charged residues in the C-terminal helix to engage in DNA binding, triggering a
270 recognizes the C-2-amino group, but not the C-6-oxo group, N-1-hydrogen, or N-7-nitrogen, of GDP for
271 m both N-domain twisting and rotation of the C domain (up to 30 degrees ) at the end of the relativel
272 -Hartwig reactions involving cleavage of the C(acyl)-O bond of aryl esters that proceed under mild co
275 Experimental and theoretical studies of the C-H amination reaction mediated by the iron dipyrrinato
276 of Cp*RhCl to accelerate the cleavage of the C-H bond of N-pentafluorophenylbenzamides, providing a n
277 of ubiquitin, two interhelical loops of the C-terminal four-helix bundle appear to penetrate the mem
278 cid replacements on lipid association of the C-terminal peptide fully recapitulated their effects on
281 cated that the PRNTase domain recognizes the C-2-amino group, but not the C-6-oxo group, N-1-hydrogen
282 2' sugar modifications and revealed that the C-terminal region of FUS is sufficient to retain ASOs in
284 signalling events have been misattributed to C-Src because they cannot be distinguished by convention
285 adiation Facility to check whether the O- to C-state transition in fully activated fibers of fast ske
286 itive, 866 of 1447 (60%) contained toxigenic C. difficile, and fecal toxin was detected in 511 of 866
287 of 683 subjects were positive for toxigenic C. difficile by direct toxigenic culture, and 141 of 682
288 BB) in rodents and selectively binds to TrkB/C receptors in vivo, as evidenced by entrectinib blockin
289 e reagent, resulting in the formation of two C-C bonds at a single carbon center bearing a C(sp(3)) o
290 pproximately 10(-4) The A-->C, G-->A, A-->U, C-->U, G-->U, U-->C, and U-->G errors mostly due to pyri
291 We identify a conserved region in the Ulp2 C terminus that mediates its specificity for rDNA-associ
295 isinfectant and disinfecting ultraviolet [UV-C] light except for C difficile, for which bleach and UV
298 inct differences in anthocyanins and vitamin C contents, on human intestinal Caco-2 cells exposed to
300 relatively frequent (10(-5)-10(-6)), whereas C-->G, U-->A, G-->C, and C-->A errors from purine-purine
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