ライフサイエンスコーパス: C2H2 zinc finger

1 ino acid sequence identified a novel type of C2H2 zinc finger.

2 , that encode proteins with highly conserved C2H2 zinc fingers.

3 a DNA binding domain with three consecutive C2H2 zinc fingers.

4 eceptors and proteins with three consecutive C2H2 zinc fingers.

5 itated by repeats of sequence motifs such as C2H2 zinc fingers.

6 dsRNA binding domain consisting of multiple C2H2 zinc fingers.

7 st three protein isoforms that contain 12-18 C2H2 zinc fingers.

8 odes several functional domains, including a C2H2 zinc finger, a leucine zipper, and a winged-helix/f

9 KS1 contains 10 C2H2 zinc fingers, a KRAB-A/B motif, and an ID sequence

10 was localized to an evolutionarily conserved C2H2 zinc finger and leucine zipper motif.

11 ferase bi-domain module with a RET1-specific C2H2 zinc finger and RNA recognition (RRM) domains.

12 des a large protein containing 12 widespread C2H2 zinc fingers and 3 motifs containing periodic proli

13 Characteristic motifs of C2H2 zinc fingers and leucine heptad repeats are present

14 aa, each having a DNA-binding domain (eight C2H2 zinc fingers) and a proline-rich transcription acti

15 C2H2 zinc fingers are found in several key transcription

16 C2H2 zinc finger bearing proteins are a large superfamil

17 The C2H2 zinc finger (C2H2-ZF) is the most numerous protein

18 These data show that single C2H2 zinc fingers can bind RNA specifically and suggest

19 The C2H2 zinc-finger-containing transcription factors encode

20 C2H2 zinc fingers define the largest transcription facto

21 gle DNA binding homeodomain but lacks both a C2H2 zinc finger DNA binding domain and an apparent Dig1

22 transcription factors that share a common 3 C2H2 zinc finger DNA binding domain and have broad activ

23 is the founding member of a small family of C2H2 zinc-finger DNA-binding proteins that carry out cri

24 t integrates crystallographic information of C2H2 zinc finger-DNA complexes with binding data from 11

25 We show that the conserved N-terminal C2H2 zinc finger domain is essential for direct DNA bind

26 ar domain structure, including an N-terminal C2H2 zinc finger domain, a central putative core transpo

27 ee different protein isoforms that contain a C2H2 zinc-finger domain.

28 Half of all human transcription factors use C2H2 zinc finger domains to specify site-specific DNA bi

29 the C-terminal 174 amino acids contains five C2H2 zinc finger domains, and the N terminus (residues 1

30 alternative splicing to one of four pairs of C2H2 zinc-finger domains (Z1, Z2, Z3, and Z4).

31 re, that combines two functionally essential C2H2 zinc-finger domains, which are probably involved in

32 We demonstrate that mutations of the C2H2 zinc fingers encoded by the him-8 (high incidence o

33 rotein 1) is one member of a small family of C2H2 zinc finger-encoding sequences previously character

34 We now find that the hunchback/Ikaros-like C2H2 zinc-finger factor ztf-16 is also required.

35 motifs for the nuclear hormone receptor and C2H2 zinc finger families and reveal unexpected diversit

36 ers indicates that ZBP-89 is a member of the C2H2 zinc finger family subclass typified by the Drosoph

37 C2H2 zinc-finger family members are key targets of DE mi

38 Here we provide evidence for a C2H2 zinc finger gene family with similarity to Ikaros a

39 A novel C2H2 zinc finger gene, ZNF277, has been localized to hum

40 ription factors and is found in more than 60 C2H2 zinc finger genes in the human genome, including th

41 ntrotus purpuratus genome, we identified the C2H2 zinc finger genes indicated in the sequence, and ex

42 We have isolated Kruppel-type (C2H2) zinc-finger genes, ZIM3 (zinc-finger gene 3 from i

43 Examples explored in this study include C2H2 zinc finger, homeodomain and bHLH DNA-binding motif

44 tobacco has a higher proportion of ERF/AP2, C2H2 zinc finger, homeodomain, GRF, TCP, zinc finger hom

45 , a class of zinc finger proteins containing C2H2 zinc fingers in tandem arrays of two or three is pr

46 The C2H2 zinc finger is one of the most abundant protein dom

47 The C2H2 zinc finger is the most commonly utilized framework

48 The C2H2 zinc finger is the most prevalent protein motif in

49 roteins that contain two atypical Cys2/His2 (C2H2) zinc finger-like domains that are evolutionarily w

50 ferentiation via an evolutionarily conserved C2H2 zinc finger motif.

51 milar DNA binding structure of four and five C2H2 zinc finger motifs (ZF), respectively.

52 ists of a basic N-terminal region with seven C2H2 zinc finger motifs and an acidic C-terminal region

53 Sequence analysis reveals eight C2H2 zinc finger motifs at the C-terminus of ZNF210 and

54 Members of one group include C2H2 zinc finger motifs.

55 ption factors characterized by seven to nine C2H2 zinc finger motifs.

56 on factor that contains a BTB/POZ domain and C2H2 zinc finger motifs.

57 The predicted Tef protein contains three C2H2 zinc-finger motifs, one at the amino terminus and t

58 brid screen, encoded a protein containing 29 C2H2 zinc fingers of the TFIIIA type.

59 In animal systems the C2H2 zinc finger protein (ZFP) gene family is the larges

60 eotide primer, for the facile isolation of a C2H2 zinc finger protein cDNA (Pszf1) from pea petals.

61 The die-1 gene encodes a C2H2 zinc finger protein containing four fingers, which

62 C2H2 zinc finger protein genes encode nucleic acid-bindi

63 nine aminopeptidases (MetAPs), and Rei1 is a C2H2 zinc finger protein whose function in ribosome biog

64 Here, we report that ZFP3, a nuclear C2H2 zinc finger protein, acts as a negative regulator o

65 Roaz, a rat C2H2 zinc finger protein, plays a role in the regulation

66 e identification of a SCAN domain-containing C2H2 zinc finger protein, ZNF24, that represses the tran

67 e contains binding sites for a non-canonical C2H2 zinc finger protein.

68 ption of 5S rRNA genes and is the archetypal C2H2 zinc finger protein.

69 The C2H2 zinc-finger protein Pita binds to several BX-C boun

70 tlp-1 encodes a C2H2 zinc-finger protein that is a member of the Sp fami

71 him-8 encodes a C2H2 zinc-finger protein that is expressed during meiosi

72 We show that lin-48 encodes a C2H2 zinc-finger protein that is similar to the product

73 Mutants of pita, which encodes a C2H2 zinc-finger protein, are homozygous lethal and show

74 We cloned ehn-3, and found that it encodes a C2H2 zinc-finger protein.

75 ists of 11 exons and encodes a Kruppel-type (C2H2) zinc-finger protein with a conserved Kruppel-assoc

76 er gene 1), encoding a typical Kruppel-type (C2H2) zinc-finger protein, located within 30 kb of a kno

77 , KRIP-1 interacts with the KRAB-A region of C2H2 zinc finger proteins and may mediate or modulate KR

78 C2H2 zinc finger proteins that do not bind arsenic were

79 criptomic profiling of three mutants lacking C2H2 zinc finger proteins, ypr013cDelta,ypr015cDelta and

80 found near the N-terminus of a subfamily of C2H2 zinc finger proteins.

81 tal biological processes: DNA recognition by C2H2 zinc-finger proteins and homology-directed repair o

82 C2H2 zinc-finger proteins play important roles in plant

83 Here, we show that a family of four related C2H2 zinc-finger proteins plays a central role in these

84 ted Rox7, is shown here to be Mot3, a global C2H2 zinc finger regulator.

85 LA (SAP) genes and novel subfamilies of BES, C2H2 zinc finger, SAP, and NAC genes.

86 c-binding motifs in the form of two separate C2H2 zinc finger sequences.

87 xidase protein, AtSWP1, and a plant-specific C2H2 zinc finger-SET domain protein, AtCZS, interact wit

88 large and highly variable numbers of tandem C2H2 zinc finger (tandem ZF) transcription factor protei

89 that the ASE motif is a binding site for the C2H2 zinc finger TF CHE-1, which is essential for the co

90 yeast fbp1 gene, binding of Rst2 (a critical C2H2 zinc-finger TF) is mediated by a local loop structu

91 a physical interaction between UNC-3 and the C2H2 zinc finger transcription factor PAG-3, the mammali

92 Here, we describe lsy-2, a novel C2H2 zinc finger transcription factor that is required f

93 thought to occur only in eukaryotes, a novel C2H2 zinc finger transcription factor, Ros, which regula

94 e observed upon postembryonic removal of two C2H2 zinc finger transcription factors, die-1 and che-1,

95 nding profiles for a benchmark set of eleven C2H2 zinc finger transcription factors, five of known an

96 logenetically conserved binding site for the C2H2 zinc-finger transcription factor CHE-1, a previousl

97 logos for the DNA-binding preferences of the C2H2 zinc-finger transcription factor family members.

98 OVOL2 encodes ovo-like zinc finger 2, a C2H2 zinc-finger transcription factor that regulates mes

99 JAGGED (JAG), a gene that encodes a putative C2H2 zinc-finger transcription factor, as a key regulato

100 BCL11 proteins are related C2H2 zinc-finger transcription factors that act as trans

101 a nematode-specific, fast-evolving family of C2H2 zinc-finger transcription factors, lsy-27, is mutat

102 RABBIT EARS (RBE) encodes a C2H2 zinc finger transcriptional repressor and is requir

103 Here, we show that the C2H2 zinc finger transcriptional repressor encoded by RA

104 ction of two conserved DNA-binding motifs, a C2H2 zinc finger (ZF) and a Myb motif, located within th

105 hrough sequence-specific DNA binding via its C2H2 zinc finger (ZF) tandem array, which is highly poly