ライフサイエンスコーパス: CCA-adding enzyme

1 RNAs and bona fide tRNAs is monitored by the CCA-adding enzyme.

2 pin down the unusual evolution of eukaryotic CCA-adding enzymes.

3 nd the eubacterial Escherichia coli class II CCA-adding enzymes.

4 as to be added post-transcriptionally by the CCA-adding enzyme, a specialized nucleotidyltransferase.

5 Intriguingly, with the CCA-adding enzyme acting as a molecular vise, the RNAs p

6 The tRNA CCA-adding enzyme adds CCA stepwise to immature transfer

7 The CCA-adding enzyme adds CCA to the 3'-end of tRNA one nuc

8 not encoded, but must be synthesized by the CCA-adding enzyme after 3' end cleavage.

9 ria and some bacteria and must be added by a CCA-adding enzyme after removal of the 3' end trailer.

10 The eubacterial, eukaryotic, and archaeal CCA-adding enzymes all share a single active-site signat

11 ses, TRF4/sigma-family polymerases, archaeal CCA-adding enzymes and uridilyltransferases from trypano

12 s distinct from the mRNA poly(A) polymerase, CCA-adding enzyme, and nonspecific terminal transferase.

13 llest efficient substrate for class I and II CCA-adding enzymes, and that CCA addition to U2 snRNA ma

14 Transfer RNA nucleotidyltransferases (CCA-adding enzymes) are responsible for the maturation o

15 olobus shibatae and Methanococcus jannaschii CCA-adding enzymes, are also capable of poly(C) synthesi

16 The CCA-adding enzyme ATP(CTP):tRNA nucleotidyltransferase b

17 s faithfully constructed and repaired by the CCA-adding enzyme (ATP(CTP):tRNA nucleotidyltransferase)

18 d, and sometimes constructed de novo, by the CCA-adding enzyme [ATP(CTP):tRNA nucleotidyltransferase]

19 The CCA-adding enzyme [ATP(CTP):tRNA nucleotidyltransferase]

20 The CCA-adding enzymes [ATP(CTP):tRNA nucleotidyl transferas

21 The CCA-adding enzymes [ATP(CTP):tRNA nucleotidyl transferas

22 CCA-adding enzymes [ATP(CTP):tRNA nucleotidyltransferase

23 CCA-adding enzymes build and repair the 3'-terminal CCA

24 The CCA-adding enzyme builds and repairs the 3' terminus of

25 U2 snRNAs were good substrates for the human CCA-adding enzyme but were inactive with the Escherichia

26 CCA-adding enzymes catalyze the addition of CCA onto the

27 logous and heterologous class I and class II CCA-adding enzymes could add 3'-terminal A, CA, or CCA t

28 idyl transferase superfamily, which includes CCA-adding enzymes, DNA polymerases and eukaryotic nucle

29 tor stem remains fixed on the surface of the CCA-adding enzyme during C and A addition.

30 ic mutations in TRNT1, the gene encoding the CCA-adding enzyme essential for maturation of both nucle

31 termined the crystal structures of a class I CCA-adding enzyme from Archeoglobus fulgidus (AfCCA) and

32 e 3.0 A resolution crystal structures of the CCA-adding enzyme from Bacillus stearothermophilus and i

33 Intriguingly, the CCA-adding enzyme from the archaeon Sulfolobus shibatae

34 Until recently, all CCA-adding enzymes from all three kingdoms appeared to b

35 All previously characterized CCA-adding enzymes from all three kingdoms are single po

36 ing CCA to the 3' ends of these transcripts, CCA-adding enzymes from all three kingdoms of life add C

37 Intriguingly, the Thermatoga maritima CCA-adding enzyme groups with the A-adding enzymes, sugg

38 e ancestral and the horizontally transferred CCA-adding enzymes have survived.

39 We were able to transform the CCA-adding enzyme into a (U,G)-adding enzyme that incorp

40 e also transformed the B. stearothermophilus CCA-adding enzyme into a dCdCdA-adding enzyme by mutatin

41 and we transformed the B. stearothermophilus CCA-adding enzyme into a poly(C,A) polymerase by mutatio

42 We show that the CCA-adding enzymes of animals originated from a horizont

43 of the class I archaeal Sulfolobus shibatae CCA-adding enzyme on eukaryotic poly(A) polymerase and m

44 We found that the CCA-adding enzyme plays a key role in tRNA quality contr

45 CCA-adding enzymes polymerize CCA onto the 3' terminus o

46 The CCA-adding enzyme repairs the 3'-terminal CCA sequence o

47 by the class II Bacillus stearothermophilus CCA-adding enzyme structure, we introduced mutations des

48 dies show that the class II Escherichia coli CCA-adding enzyme synthesizes poly(C) when incubated wit

49 The CCA-adding enzyme (tRNA nucleotidyltransferase) builds a

50 The CCA-adding enzyme (tRNA nucleotidyltransferase) synthesi

51 The CCA-adding enzyme, which builds and repairs the 3' termi