ライフサイエンスコーパス: CD

1 CD had significantly lower DeltaBPND in the striatum (P=

2 CD is a non-IgE hypersensitivity to certain cereal prote

3 CD spectroscopy indicated that wild-type AQP2 and the ph

4 CD stayed inpatient for 5-7 days prior to the scans to s

5 CD studies demonstrated the specificity of A-ZIP53 as it

6 ic and 1421 non-TG2-specific gut PCs from 10 CD patients.

7 nion-like structure, noted [P2W18O62]@2gamma-CD@{Mo154} has been characterized by single-crystal X-ra

8 abolites in stool of 183 subjects (82 UC, 50 CD, and 51 healthy controls) were determined.

9 fects of the HttQ111 allele on the C57BL/6J, CD-1, FVB/NCr1, and 129S2/SvPasCrl genetic backgrounds,

10 s to date outside of blood banks, we found a CD prevalence of 1.24%.

11 Attempts to obtain a CD-MOF containing only Li(+) ions resulted in nonporous

12 ndomized (1:1 ratio) to home-based HT with a CD (CD group) or iHT performed by qualified therapists (

13 g-term effectiveness of home-based HT with a CD is noninferior to iHT performed by therapists in pedi

14 ight absorption compared to amorphous CDs (a-CD) yet undoped g-CD display limited photosensitizer abi

15 indings support a GED-0301 benefit in active CD.

16 0) protects the cochlear basal turn of adult CD-1Cx30(A88V/A88V) mice from degeneration and rescues h

17 ts, CD/UC 84/28, male/female 50/62, mean age CD/UC: 36/35 years) were enrolled in this consecutive co

18 Neither alpha- nor HP-alpha-CDs formed inclusion complexes, while beta-, HP-beta- an

19 anced light absorption compared to amorphous CDs (a-CD) yet undoped g-CD display limited photosensiti

20 e to severe PS, 10 subjects with both AD and CD, and 10 HC with no history of skin disease was analys

21 Islet autoimmunity and CD autoimmunity were defined as being positive for islet

22 orescence imaging of a single carbon dot and CD aggregate was simply achieved using filter-free dark-

23 change was validated by 3D fluorescence and CD spectrum.

24 and increased FENO , EOS, PAI-1, FXIII, and CD in patients with asthma compared with controls.

25 Techniques such as SEC, MS, and CD, traditionally used in the physicochemical characteri

26 ures in serum from subjects with AD, PS, and CD compared with healthy controls (HC).

27 ciated with an increased risk of both UC and CD (OR: 2.91; 95% CI: 1.49, 5.68 and OR: 3.00; 95% CI: 1

28 UC and CD were genetically more similar to each other (rG = 0.5

29 The method relies on fast UV and CD measurements, which provide accurate stereochemical i

30 complex formed between anti-CA125, CA125 and CDs-Aptamer and decreasing of fluorescence response sign

31 segmental distribution along the nephron and CDs.

32 rbon dots (CDs) functionalized with aptamer (CD-aptamer) used as detection probe and PAMAM-Dendrimers

33 Mucosal healing was defined as CD Endoscopic Index of Severity of 0 in CD or Mayo endos

34 cluding many important glycoproteins such as CD molecules.

35 The best CD in this respect was MbetaCD (KF=606.65+/-30.18M(-1)),

36 nd in several alterations in the cy3glc-beta-CD DSC thermogram.

37 with solid amorphous beta-cyclodextrin (beta-CD) was investigated.

38 Here we report a beta-cyclodextrin (beta-CD)-based polymer network with higher affinity for PFOA

39 he surface of N, S codoped carbon dots (beta-CD-CDs).

40 using 17% MC included 99.63mg of TTO/g beta-CD.

41 c profile and bioavailability of the HP-beta-CD agent.

42 ngs, we sought to design a family of HP-beta-CD pro-drug delivery vehicles, known as polyrotaxanes (P

43 The HP-beta-CD samples showed generally higher activity against the

44 rocapsules were much greater: 19.9% (HP-beta-CD) and 22.7% (IN).

45 e 2-hydroxypropyl-beta-cyclodextrin (HP-beta-CD) has shown efficacy as a potential NPC therapeutic by

46 Hydroxypropyl-beta-cyclodextrin/ANE (HP-beta-CD/ANE) inclusion complexes were prepared and encapsulat

47 ater and demonstrate the versatility of beta-CD-based adsorbents.

48 The beta-CD polymer reduces PFOA concentrations from 1 mug L(-1)

49 intestinal digestion, complexation with beta-CD allowed anthocyanins degradation to be slowed down.

50 Complexation with beta-CD showed a thermal stabilization of cy3glc, resulting o

51 nance energy transfer (FRET) signals between CDs and AuNPs as nanoquenchers, the fluorescence signal

52 listic category learning performance in both CD and HC.

53 ficiently been obtained and characterized by CD spectra.

54 RNA 1 (ADAR1, hZalphaADAR1), as confirmed by CD, NMR, and microscale thermophoresis studies.

55 on but tends to form a helix as evidenced by CD and NMR studies.

56 at there are only two states identifiable by CD, one before and another after membrane binding; all o

57 alpha-helix propensities varied as shown by CD spectroscopy.

58 Solution studies by CD and NMR confirm left-handedness of the helical foldam

59 ized (1:1 ratio) to home-based HT with a CD (CD group) or iHT performed by qualified therapists (iHT

60 Sour cherries were dried by convectional (CD) at 50, 60, and 70 degrees C and by hybrid (HD; micro

61 NP through an azobenzene (Azo)-cyclodextrin (CD) host-guest interaction.

62 Readily available cyclodextrins (CDs) with an inherent hydrophobic internal cavity and hy

63 resolved by encapsulation in cyclodextrins (CDs).

64 ogical activity) and modified cyclodextrins (CDs) was studied.

65 Chemically defined (CD) and hydrolysate-supplemented media formulations were

66 .001) but not between children who developed CD and those who did not within the same country (P > 0.

67 By careful circular dichroism (CD) analyses of daptomycin with Ca(2+) and PG-containing

68 still functional; (iii) circular dichroism (CD) analysis confirmed the complexation of unmodified an

69 Circular dichroism (CD) and mass spectrometry studies with equimolar mixture

70 soldiers" approach using circular dichroism (CD) experiments, we are able to obtain detailed insights

71 Circular dichroism (CD) spectroscopy is extensively utilized for determining

72 was characterized by UV, circular dichroism (CD), and X-ray photoelectron spectroscopy (XPS).

73 A control diet (CD) and Western diet (WD), which contains high fat and c

74 Female mice were placed on control diet (CD) or folic acid-supplemented diet (FASD) throughout ma

75 ), lung-resident cluster of differentiation (CD) 11b(+) conventional DCs (cDCs) and monocyte-derived

76 ur cell-specific cluster of differentiation (CD) proteins used to count cells by flow cytometry, band

77 of inflammatory cluster of differentiation (CD)54+CD80 and proresolution markers CD163+CD206], and A

78 fferent neurons excites calyx and dimorphic (CD) afferents.

79 Wheat allergy (WA) and celiac disease (CD) are well-defined entities, but are becoming a fracti

80 antibiotic use and islet or celiac disease (CD) autoimmunity in genetically at-risk children prospec

81 is a severe complication of celiac disease (CD) characterized by the presence of an enlarged clonal

82 Celiac disease (CD) is an immune-mediated disorder characterized by an a

83 ssessed how the diagnosis of Celiac Disease (CD) is made and how the new ESPGHAN guidelines can be ap

84 ontrol and Prevention (CDC), Chagas disease (CD) may affect 1.31% of Latin American immigrants in the

85 ng ulcerative colitis (UC) or Crohn disease (CD) were elevated in carriers of the SLC2A14 SNP rs28895

86 Studies of Crohn disease (CD), a chronic inflammatory disease of the intestinal tr

87 312 patients diagnosed with Crohn's disease (CD) and 361 with ulcerative colitis (UC).

88 or patients with refractory Crohn's disease (CD) and fistulizing CD, respectively.

89 l diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are complex chronic inf

90 Pathogenesis of Crohn's disease (CD) involves immune and microbial dysregulation, induced

91 ic therapeutic responses in Crohn's disease (CD) patients induced by chimeric anti-TNF mAbs.

92 compared with patients with Crohn's disease (CD)-associated colitis or without inflammatory bowel dis

93 is a common complication of Crohn's disease (CD).

94 h outcomes of patients with Crohn's disease (CD).

95 ated in the pathogenesis of Crohn's disease (CD).

96 tive colitis [UC], 234 with Crohn's disease [CD]; 236 male), enrolled in Germany from August 2013 thr

97 to comorbid disorders (eg, conduct disorder [CD], oppositional defiant disorder [ODD], or learning di

98 ctivity, callousness) in conduct-disordered (CD) youth.

99 a relationship between circadian disruption (CD) and PD, whether this is secondary to the motor sympt

100 netical protein pairs, CRY2 linked to DNMT3A-CD or TET1-CD and CIB1 fused to a Transcription Activato

101 n is mediated by a conserved common docking (CD) domain within the carboxyl-terminal domains of ERK3

102 ine, ThreaDomEx, for both continuous domain (CD) and discontinuous domain (DCD) structure predictions

103 gnal amplification strategy the carbon dots (CDs) functionalized with aptamer (CD-aptamer) used as de

104 Somatic mutations in candidate driver (CD) genes are thought to be responsible for at least som

105 e of pigment-containing carotenoid droplets (CD).

106 s deletion of ILK in renal collecting ducts (CD) of Ilk(fl/fl) ;Pkhd1-Cre mice caused tubule dilation

107 beta specifically in renal collecting ducts (CDs).

108 cone-rod dystrophy (CRD) or cone dystrophy (CD) harboring potential pathogenic variants in the CDHR1

109 aCD, and HPgammaCD) were used to electrospin CD/linalool-IC-NFs.

110 Eleven CD and 12 healthy controls (HC) completed two positron e

111 nto blue-, green-, yellow-, and red-emitting CD aggregates by tuning the concentration of fatty acids

112 ructural studies have suggested the extended CD-loop and hydrogen-bonding interaction network within

113 anges in the spleen of adult male and female CD-1 mice exposed to 4 to 40,000 mug/kg/day BPA or 0.02

114 Finally, CDs as well-known "green" molecular hosts have also been

115 ractory Crohn's disease (CD) and fistulizing CD, respectively.

116 ur calculation of EE uses published data for CD of biomolecules and accepted magnitude for Archaean e

117 f genome-wide significance were detected for CD.

118 We performed 3 meta-analyses each for CD, UC, and IBD (CD and UC combined), comparing data for

119 istic models which gave the best fitting for CD and HD, respectively.

120 trointestinal infections may be relevant for CD development.

121 current smoking in relation to the risk for CD (frameshift variant fs1007insC; rs5743293).

122 d environmental factors that affect risk for CD.

123 ed to apply the usual diagnostic work-up for CD according to their diagnostic facilities.

124 is of carbohydrate metal-organic frameworks (CD-MOFs) in a combination of alkali-metal cations.

125 t-mediated slow excitation, we recorded from CD afferents innervating the turtle posterior crista dur

126 Furthermore, linalool release from CD/linalool-IC-NFs inhibited growth of model Gram-negati

127 nificantly enriched in baseline samples from CD patients achieving remission.

128 mpared to amorphous CDs (a-CD) yet undoped g-CD display limited photosensitizer ability due to low ex

129 atalytic amount of gamma-cyclodextrin (gamma-CD) in water has been developed to give substituted isox

130 12(H2O)6](2+), and gamma-cyclodextrin (gamma-CD).

131 Thymol (THY)/gamma-Cyclodextrin(gamma-CD) inclusion complex (IC) encapsulated electrospun zein

132 toexcited D-/L-Trp enantiomers and rGO/gamma-CD giving rise to an enantioselective photoluminescence

133 ty of the inner and outer faces of the gamma-CD for the polyoxometalate surfaces.

134 s exhibit a common feature wherein the gamma-CD moiety interacts with the Dawson-type POMs through it

135 The formation of THY/gamma-CD-IC (1:1 and 2:1) was proved by experimental (X-ray di

136 s observed in TGA and stability of THY/gamma-CD-IC (2:1) was higher, as shown by a modelling study.

137 NF (2:1) than zein-THY-NF and zein-THY/gamma-CD-IC-NF (1:1).

138 It is worth mentioning that zein-THY/gamma-CD-IC-NF (2:1) preserved much more THY as observed in TG

139 ch more THY was released from zein-THY/gamma-CD-IC-NF (2:1) than zein-THY-NF and zein-THY/gamma-CD-IC

140 It was demonstrated that zein-THY/gamma-CD-IC-NF (2:1) was most effective in inhibiting the grow

141 rospun zein nanofibrous webs (zein-THY/gamma-CD-IC-NF) were fabricated as a food packaging material.

142 2+) ion is closely embedded within two gamma-CD units to give a supramolecular ditopic cation, suitab

143 ral enantiomers to form complexes with gamma-CD in different molecular orientations as demonstrated b

144 and HP-gamma-CDs provided AL type and gamma-CDs BS phase solubility diagrams.

145 omplexes, while beta-, HP-beta- and HP-gamma-CDs provided AL type and gamma-CDs BS phase solubility d

146 However, no gag and gp41-CD mutations definitively responsible for reduced PI sus

147 acid mutations developed in gag and in gp41-CD in both the PI- and NNRTI-treated groups.

148 the high absorption coefficient of graphitic CDs to be translated into high charge extraction for eff

149 All graphitized CDs show significantly enhanced light absorption compare

150 in spontaneous ileitis that resembled human CD in symptoms and histology.

151 ed 3 meta-analyses each for CD, UC, and IBD (CD and UC combined), comparing data for never vs ever sm

152 nly this population; we also replicated IBD, CD, and UC loci identified in European populations.

153 anial inoculation of 1-d-old immunocompetent CD-1 mice with 1 x 10(4) infectious focus units (IFU) of

154 More importantly, CDs-antibody hybrid was achieved in selective imaging of

155 d as CD Endoscopic Index of Severity of 0 in CD or Mayo endoscopic sub-score of 0-1 for patients with

156 l (NOAEL) of GS-AuNPs was >1000 mg kg(-1) in CD-1 mice.

157 ET2 disease risk variants were associated in CD patients with more complicated disease or resistance

158 activity in the right habenula decreased in CD in the abstinence/saline condition vs acute cocaine a

159 IBD patients were that they were elderly in CD and were on higher doses of steroids.

160 l stem cell and progenitor cell expansion in CD patients, human cells, and preclinical mouse models.

161 mmune response to in vivo gluten exposure in CD has not been systematically investigated yet.

162 Baseline GAP-43 expression was higher in CD animals compared to control non-CD rats.

163 m GAP-43 levels were significantly higher in CD rats that developed spontaneous seizures.

164 mucosal tissues and DNA hypermethylation in CD patients requiring surgical intervention.

165 e-dependent activity for losses increased in CD vs HC in the right inferior parietal lobe post-cocain

166 unctional status of mesenteric lymphatics in CD.

167 nated hepatic neutrophils and lymphocytes in CD-fed, but not WD-fed, FXR KO mice.

168 c changes in immune dysfunctions observed in CD and suggest the lymphatic system as new target for th

169 itudes of cochlear microphonic potentials in CD-1Cx30(A88V/A88V) and CBA/J mice are comparable.

170 sical electron transfer processes present in CD photocatalytic systems is outlined and various avenue

171 amount of linalool (45-89%) was preserved in CD/linalool-IC-NFs, due to enhancement in the thermal st

172 ential biomarker for epilepsy progression in CD.

173 de-related activity for gains was reduced in CD in the left cingulate gyrus post-cocaine and in the l

174 cochlear amplification is greatly reduced in CD-1Cx30(A88V/A88V) mice.

175 tly reduced seizure duration and severity in CD rats after acute seizures with subsequent reduction i

176 ed with inattention and negative symptoms in CD, and with poorer working memory and probabilistic cat

177 sion of miR-200c is nearly 70-fold higher in CDs compared with PTs.

178 early in life has been suggested to increase CD risk.The aim of this study was to evaluate this hypot

179 Increased CD levels, vasopermeability, and alteration in junctiona

180 iral induction upon mixing two independently CD-silent solutions of the achiral (soldier) and chiral

181 processing in cocaine-dependent individuals (CD) is not well understood, despite the relevance of suc

182 t the cytoplasmic domain subunit interfaces (CD-Is) of eukaryotic Kir channels control channel gating

183 The bare complex is CD-silent, but coordination of an enantioenriched substr

184 However, known CD mutations were evident in only a fraction of CH cases

185 =10 mg/dL differences between LDL-CF and LDL-CD compared with 25% and 20% of patients, respectively,

186 fferences >/=10 mg/dL between LDL-CF and LDL-CD, whereas only 2% and 3% of patients, respectively, ha

187 absolute and percent differences between LDL-CD and estimated LDL-C (LDL-CN or LDL-CF) was stratified

188 used to directly measure LDL-C content (LDL-CD).

189 ccuracy was defined as the percentage of LDL-CD falling within an estimated LDL-C (LDL-CN or LDL-CF)

190 Like CD, RCDII is strongly associated with HLA-DQ2, suggestin

191 infected in Los Angeles County alone, making CD an important public health concern.

192 RC) and macrophage-derived chemokine (MDC)), CD (10 proteins), and PS (kynureninase (KYNU)).

193 rresponding reductions from baseline in mean CD activity index scores were -124, -112, and -133 point

194 lve IBD patients (with 214 TDM measurements, CD/UC 84/28, male/female 50/62, mean age CD/UC: 36/35 ye

195 in kinase A (PKA) activation, which mediates CD dispersion in xanthophores, phosphorylates Plin6 on c

196 Among the natural and modified CDs analyzed HPbetaCD was the best for encapsulating RA.

197 The monodisperse CDs can self-assemble into blue-, green-, yellow-, and r

198 III)-induced aggregation of the monodisperse CDs.

199 The GC/N-CDs electrode shows higher electrocatalytic activity tow

200 The GC/N-CDs electrode shows the limit of detection of 13x10(-10)

201 ous strategies for the preparation of native CDs-modified inorganic nanomaterials such as metal, meta

202 oof of concept, its ability to enhance Neph1-CD and ZO-1 binding was tested.

203 higher in CD animals compared to control non-CD rats.

204 some CH cases could arise in the absence of CD mutations as a result of neutral drift acting on a sm

205 ials, family history of CD, and awareness of CD.

206 o further understand the structural basis of CD-I control of Kir channel gating, we examined the effe

207 lar membrane are enhanced in the cochleae of CD-1Cx30(A88V/A88V) compared to CBA/J mice with sensitiv

208 s confirmed by single value decomposition of CD and UV spectra.

209 Here, we have also examined the effect of CD on endothelial-pericyte interactions, as well as the

210 anonymous questionnaire surveyed families of CD patients treated with EEN over 1 year.

211 the prevalence of HP in a selected group of CD patients with quiescent disease, and to assess the in

212 Autoantibodies against TG2 are a hallmark of CD, and anti-TG2 IgA-producing gut PCs accumulate in pat

213 origin, housing materials, family history of CD, and awareness of CD.

214 CI = 2.8-13.5; P < .001), prior knowledge of CD (aOR = 2.4; 95% CI = 1.0-5.8; P = .047), and exposure

215 gical patterns linked to clinical outcome of CD, conserved among the genetically diverse infecting st

216 An overview of CD types, synthesis and properties is given along with a

217 ating the role of MCs in the pathogenesis of CD.

218 7 parameters), and clinical presentations of CD (2 parameters).

219 In the largest screening of CD in the United States to date outside of blood banks,

220 rine application enhanced the sensitivity of CD afferents to mechanical stimulation, suggesting that

221 here are believed to be multiple subtypes of CD, which contributes to its observed clinical heterogen

222 yzed its safety and efficacy in treatment of CD in a phase 2a study.

223 However, treatment of CD patients with etanercept, a decoy receptor that binds

224 Firstly, the effect of the type of CD on the encapsulation process was studied.

225 The association of a hydrophobic cavity of CDs with metal ions or various inorganic nanoparticles i

226 In experiments 1 and 2, we trained older CD-1 mice to lever press for opportunities to attack you

227 ed the impact of established risk factors on CD diagnosis, including sex, country of origin, housing

228 f dipeptidyl peptidase-4 (DPP4) inhibitor on CD in endothelial-pericyte interactions in vitro and in

229 of gluten consumed from age 10 mo onward on CD development.Mean daily gluten intakes from 10 mo onwa

230 ensing platforms such as lab-on-chip, lab-on-CD, lab-on-paper etc.

231 patients with UC from those with colon-only CD based on increased mucosal expression of genes that m

232 th UC compared with patients with colon-only CD.

233 h the development of autoimmunity for T1D or CD.

234 biotics in young children at risk for T1D or CD.

235 ely followed up for type 1 diabetes (T1D) or CD.

236 ; the pellets were reconstituted in water or CD solution and the dispersions were characterized for t

237 nd another after membrane binding; all other CD spectra are linear combinations of the two.

238 Utilizing BPA as a model exposure, pregnant CD-1 mice were administered 25mug/kg/day BPA via osmotic

239 Cocultured cells that were treated with pro-CD demonstrated a significant decrease in the expression

240 With pro-CD treatment, there was a significant increase in the ph

241 e treated with DPP4 inhibitor along with pro-CD.

242 ly approach to enable researchers to produce CD spectra from protein atomic coordinates.

243 -based approach to the generation of protein CD spectra from atomic coordinates.

244 VCE, suggesting it might be part of proximal CD.

245 e of HP infection in patients with quiescent CD is relatively low.

246 treatment with ustekinumab for a refractory CD and which ended in miscarriage.

247 tients receiving GED-0301 were in remission (CD activity index score <150); corresponding reductions

248 We also report CD and UV-Vis spectroscopy studies of adducted human Hb

249 rgic inflammation was not different in ROCK2(CD)(4Cre) vs. control mice.

250 convective drying at 60 degrees C and 2m/s, CD sample) on apple (var. Granny Smith) behavior during

251 potential biomarker for patients with severe CD.

252 mbination of molecular dynamics simulations, CD response calculations, and experiments on an AT-seque

253 Moreover, the presence of HP-ss-CD in the aqueous phase of CDL protected them during fre

254 Free-standing CD/linalool-IC-NFs facilitate maximum loading of linaloo

255 The as-synthesized CDs exhibited small particle size variation (2.7 +/- 0.2

256 Bonferroni correction) associated with T1D, CD, RA and T2D.

257 tein pairs, CRY2 linked to DNMT3A-CD or TET1-CD and CIB1 fused to a Transcription Activator-Like Elem

258 aken together, our findings demonstrate that CD by triggering a robust neuroinflammatory reaction and

259 to non-drug reward processing suggests that CD experience a general alteration of reward function an

260 after treatment, 46 children (36.8%) in the CD group and 62 (50.1%) in the iHT group were successful

261 imit was set at 50% treatment success in the CD group, with a maximum of 25% difference in treatment

262 at influences the shape and magnitude of the CD spectrum produced.

263 fted emission enables the development of the CD-based ratiometric sensor for Fe(III) ions and pyropho

264 N-glycan knockouts on the CD demonstrate that N-glycosylation has little impact on

265 These findings imply that the CD strength of the QD exciton transition(s) may be used

266 was seen to form a 1:1 complex with all the CDs tested.

267 ut the conjugation of the fluorophore to the CDs, the particle aggregation-induced red-shifted emissi

268 g time and increased drying rate compared to CD.

269 7) that interact with smoking in relation to CD risk.

270 associated with increased susceptibility to CD and UC (OR: 2.12; 95% CI: 1.33, 3.36 and OR: 1.61; 95

271 ios and 95% confidence intervals for time to CD diagnosis by infection exposure, adjusting for sex, c

272 is given along with a discussion of tuneable CD properties that can be optimised for applications in

273 e M-current candidates suggested that turtle CD afferents express KCNQ3, KCNQ4, and ERG1-3 potassium

274 re also functionalized with PEG (i.e., UCNP-(CD/Azo)-siRNA/PEG NPs), targeting ligands (i.e., EGFR-sp

275 de the most prominent examples of unmodified CDs' inclusion complexes with organometallic guests and

276 Here, using CD spectroscopy, isothermal titration calorimetry, and s

277 We thus developed an in vivo model using CD-1 mice with an intracerebroventricular injection of 1

278 biodistribution studies were performed using CD-1 nu/nu and LNCaP tumor-bearing CB-17 severe combined

279 luding heterocomplex pulldown assays, far-UV CD spectroscopy, the thioflavin T binding assay, transmi

280 tochemical and kinetic studies using UV/vis, CD, and (1)H NMR spectroscopy, it was established that t

281 meter and mean SR-mitochondrial distance vs. CD-WT hearts.

282 cantly augmented cardiac apoptosis in WT vs. CD-WT mice, which was prevented by co-treatment with the

283 ses of African Americans with IBD (1646 with CD, 583 with UC, and 116 inflammatory bowel disease uncl

284 ugh MCs have previously been associated with CD, functional studies have never been performed.

285 n did not show significant associations with CD development risk (HRs not significant).

286 iles allowed us to distinguish children with CD or UC from controls; profiles correlated with disease

287 In contrast, compared with CD/CU- and healthy control youths, CD/CU+ youths showed

288 performed and in all it was compatible with CD.

289 age, ECD was more inversely correlated with CD than with age (r = -0.61, P < .0001; r = -0.38, P = .

290 s with asthma, FR negatively correlated with CD, FXIII, PAI-1, FENO , and EOS and positively with FEV

291 miRNAs, we generated three mouse models with CD-specific inactivation of key miRNA pathway genes Dice

292 stinal epithelial tissues from patients with CD and embryonic fibroblasts from mice, along with enter

293 Distal ileum tissues from patients with CD had lower levels of VIL1 and GSN, increased phosphory

294 Patients with CD have extra-intestinal autoimmune comorbid conditions

295 Intestinal biopsy specimens of patients with CD were scored according to the Marsh classification and

296 Patients with CD who are eligible for HSCT have typically been failed

297 and mucosal healing (15.4% of patients with CD, 17.4% with UC).

298 with moderate to severe AD, 10 subjects with CD, 12 subjects with moderate to severe PS, 10 subjects

299 Remarkably, in the past few years CDs have appeared as attractive building units for the s

300 ared with CD/CU- and healthy control youths, CD/CU+ youths showed diminished CMA connectivity with ve