ライフサイエンスコーパス: CD4-positive

1 lation stimulated by these Dsg3 peptides was CD4 positive.

2 One-third of infiltrating T cells were CD4 positive.

3 ase-line percentage of lymphocytes that were CD4-positive, a higher weight for age, a higher height f

4 ry infiltrate, cluster of differentiation 4 (CD4)-positive and CD8(+) T-lymphocyte levels, and viral

5 tudying the entry of three SIV isolates into CD4-positive and CD4-negative cells expressing different

6 Both CD4-positive and CD4-negative peripheral blood dendritic

7 ytes, Kupffer cells, hepatic stellate cells, CD4-positive and CD8-positive lymphocytes, and cholangio

8 e, CCR5-positive cells, but the infection of CD4-positive, CCR5-positive cells was inhibited.

9 Virus bound to both CD4-positive (CD4(+)) and CD4-negative (CD4(-)) cells, i

10 tional ability to stimulate antigen-specific CD4-positive (CD4(+)) and CD8(+) T-cell responses.

11 phoid tissues and of IL-4-producing Th2-type CD4-positive (CD4(+)) T cells than did controls.

12 OVA-specific Ab and CD4-positive (CD4(+)) T-cell responses were determined.

13 CD4-positive (CD4+) T cells isolated from mucosal compar

14 Our laboratory discovered that CD4-positive (CD4+) T cells of the immune system convey

15 s mucosal adjuvant requires IL-4 and induces CD4-positive (CD4+) Th2-type responses, while nLT up-reg

16 of PSCA-vaccinated mice were infiltrated by CD4-positive, CD8-positive, CD11b-positive, and CD11c-po

17 infection of a CD4-positive precursor cell (CD4 positive/CD8 positive) with subsequent differentiati

18 B) was defined similarly, using the dates of CD4-positive cell counts or HIV-1 RNA measurements.

19 e of T-tropic HIV viruses is associated with CD4-positive cell decline and progression to AIDS, sugge

20 n immunodeficiency virus-type 1 (HIV-1) on a CD4-positive cell line expressing CCR3 and to a lesser e

21 eath related to HIV-1 infection of the human CD4-positive cell line H9, requires an ICE-like protease

22 hich this antibody blocks HIV-1 entry into a CD4-positive cell.

23 wly and inefficiently adsorbed onto cultured CD4-positive cells at 37 degrees C, and the gradual decl

24 Infection of CD4-positive cells by human immunodeficiency virus type

25 To determine whether specific infection of CD4-positive cells could be demonstrated for these recom

26 Finally, adoptive transfer of CD4-positive cells from GF, but not SPF mice induces sev

27 organs, and in the presentation of virus to CD4-positive cells in multiple locations including lymph

28 HIV-1 is able to infect cultured susceptible CD4-positive cells in standard assay conditions casts do

29 ayed increased numbers of CD25-, FoxP3-, and CD4-positive cells in the CNS.

30 ulovirus powerfully induces proliferation of CD4-positive cells originating from several different sp

31 line produces virions capable of transducing CD4-positive cells with high efficiency (up to 10(5) cel

32 Extensive fusion of CD4-positive cells with the chimeric protein containing

33 lecules were found on the plasma membrane in CD4-positive cells, 43.9 +/- 8.5% were found in CD4-nega

34 e, psi 422, psi 422 cells form syncytia with CD4-positive cells, correctly express HIV-1 structural p

35 nes in stimulating HIV-1 replication in high CD4-positive cells, including primary lymphocytes, but n

36 nalization of CXCR4 in both CD4-negative and CD4-positive cells, suggesting that gp120 is a high affi

37 kine receptors CCR5 and CXCR4 for entry into CD4-positive cells.

38 ins and can transmit bound virus to adjacent CD4-positive cells.

39 ated cell-cell fusion and virus infection of CD4-positive cells.

40 Env cells only upon exposure to soluble CD4, CD4-positive, coreceptor-negative cells, or stromal cell

41 In single-round infections using CD4-positive HeLa cells, the EnvY712A mutation impaired

42 munodeficiency virus (FIV) targets activated CD4-positive helper T cells preferentially, inducing an

43 CD4-positive human CEM-SS T-cell lines were generated wh

44 at IC(90)s, IC(99)s, or IC(> or = 99)s in a CD4-positive human lymphoblastoid cell line (H9 cells) a

45 locked cell fusion and infection with normal CD4-positive human target cells.

46 h leads to the expression of the CD4 gene in CD4-positive hybridoma cells and double-positive thymocy

47 rtantly, TIM-1 inhibits HIV-1 replication in CD4-positive Jurkat cells, despite its capability of up-

48 ion with intracellular localization in human CD4-positive Jurkat T cells.

49 s variants that grow to different extents in CD4-positive leukemic cell lines and that differ only at

50 creased IL-18BP production is a reduction in CD4-positive lymphocyte activation in response to IL-18

51 ral therapy was provided if participants had CD4-positive lymphocyte counts of fewer than 200 cells p

52 ty to cause syncytium formation or fusion in CD4-positive lymphocyte cultures.

53 contribution of these properties to in vivo CD4-positive lymphocyte depletion.

54 deficiency virus type 1 (HIV-1) infection of CD4-positive lymphocytes is accompanied by acute cytopat

55 V-1 isolates resulted in the lysis of single CD4-positive lymphocytes.

56 lation and the enhancement of replication in CD4-positive lymphocytes.

57 mal ciliated respiratory epithelia and a CD8/CD4-positive lymphocytic infiltrate that peaked at 21 da

58 numbers of immune cells, including T cells (CD4-positive), macrophages, and mast cells, at all time

59 CD4-positive membrane vesicles (MV) were isolated under

60 s were developed and were shown to express a CD4 positive memory T cell phenotype.

61 These Dsg1-reactive FS T cells exhibited a CD4-positive memory T-cell phenotype and produced a T he

62 ence the development and selection of, e.g., CD4-positive, MHC class II-specific T cells.

63 th IL-15 for 1 week normalizes their hepatic CD4-positive natural killer cell content.

64 these Kupffer cell factors promotes hepatic CD4-positive natural killer cell depletion in ob/ob live

65 vers to lipopolysaccharide, why such hepatic CD4-positive natural killer cell depletion occurs is unc

66 in [IL]-12) or enhance (e.g., IL-15) hepatic CD4-positive natural killer cell viability.

67 tokine production and the hepatic content of CD4-positive natural killer cells were compared in ob/ob

68 The livers of ob/ob mice are depleted of CD4-positive natural killer cells, components of the inn

69 mice and partially replenishes their hepatic CD4-positive natural killer cells.

70 Rather, infection of a CD4-positive precursor cell (CD4 positive/CD8 positive)

71 and replication in several cell lines and in CD4-positive primary lymphocytes.

72 ts of CD4 and replicate more aggressively in CD4-positive primary lymphocytes.

73 Tumor-reactive CD4-positive T cell clones were isolated from TIL and te

74 s were highly specific and restricted to the CD4-positive T cell population.

75 In the absence of GILT, CD4-positive T cell responses to Der p 1 are significant

76 ith a reduction in the number of circulating CD4-positive T cells (P=0.01), and reduced expression of

77 Activated CD4-positive T cells are essential in the early stages o

78 Since activated CD4-positive T cells are involved in pathogenesis of var

79 l populations, as well as the percentages of CD4-positive T cells expressing IFN-gamma and of NKp46/C

80 phoid organs, with preferential expansion of CD4-positive T cells in the recipient spleens.

81 and the cytopathicity of virus for infected CD4-positive T cells in this animal model of HIV-1 infec

82 The number of CD4-positive T cells increased by 2.8-fold in MHC I-defi

83 s II and ICAM-1 (ProAd-ICAM) can drive naive CD4-positive T cells into cell cycle, but these T cells

84 to activate Ag-specific Th1 clones and naive CD4-positive T cells isolated from TCR transgenic mice.

85 t on the formation of either mature CD8- and CD4-positive T cells or granulocytes or macrophages, but

86 om patient 888 indicated that they contained CD4-positive T cells that recognized the autologous tumo

87 Dose-dependent inhibition of activated CD4-positive T cells to HIV-1 infection with both bindin

88 ntended to engage and render gluten-specific CD4-positive T cells unresponsive to further antigenic s

89 Previous studies have shown that CD4-positive T cells vary in a predictable manner over 2

90 to HIV-1 infection by challenging activated CD4-positive T cells with CCR5-binding and CXCR4-binding

91 rate that was primarily composed of CD3- and CD4-positive T cells, CD20-expressing B cells, macrophag

92 immunodominant epitopes for gluten-specific CD4-positive T cells.

93 e 1 (HIV-1) infection is the gradual loss of CD4-positive T cells.

94 essed antigens to T cell receptors (TCRs) of CD4-positive T cells.

95 could not replicate in primary A. nancymaae CD4-positive T cells.

96 rment in the activation of these specialized CD4-positive T cells.

97 hey also had increased numbers of glomerular CD4-positive T cells.

98 as F4/80-positive macrophages/microglia and CD4-positive T cells.

99 ntigens from dying cells and present them to CD4-positive T cells.

100 marked decrease in the numbers of activated CD4-positive T cells.

101 C full-length cDNA are infectious in primary CD4-positive T cells.

102 quired for effective antigen presentation to CD4-positive T cells.

103 rogressive increase in their number of naive CD4-positive T cells.

104 s for antigen processing and presentation to CD4-positive T cells.

105 issues are enriched in macrophages (MOs) and CD4-positive T cells; however, T helper-type cytokines s

106 Flow cytometric analysis showed that CD4-positive T lymphocyte division was specifically supp

107 lecule (VCAM-1), and MHC class II as well as CD4-positive T lymphocyte infiltration was detected by i

108 The change in percentage of CD4-positive T lymphocytes (CD4%) was investigated in 10

109 essor or cytotoxic subset) predominated over CD4-positive T lymphocytes (helper cells) surrounding th

110 Infection of human CD4-positive T lymphocytes by human immunodeficiency vir

111 creased on mononuclear leukocytes, including CD4-positive T lymphocytes from HIV-positive patients, c

112 ex (MHC) class II-restricted presentation to CD4-positive T lymphocytes occurs after they are interna

113 ion aged 5.7-12.0 weeks with a percentage of CD4-positive T lymphocytes of at least 25% were randomly

114 acterial lipopeptides that are recognized by CD4-positive T lymphocytes of Mycobacterium tuberculosis

115 les, as well as the subsequent activation of CD4-positive T lymphocytes.

116 ass II (MHC II) molecules for recognition by CD4-positive T lymphocytes.

117 ion of nef led to a substantial reduction in CD4-positive T-cell depletion and delayed kinetics of pl

118 lly, relevant doses of Ze-NO induce a dermal CD4-positive T-cell infiltrate and IFN-gamma secretion.

119 detected by reverse transcription-PCR in the CD4-positive T-cell line C8166, but not in peripheral bl

120 , characterised by a T-helper 1 (Th1) biased CD4-positive T-cell response and granuloma formation, fo

121 and early CD8-positive cytotoxic T-cell and CD4-positive T-helper cell responses directed toward HIV

122 troviral therapy (HAART) on the evolution of CD4-positive T-lymphocyte (CD4 cell) count among human i

123 s evaluated population- and individual-level CD4-positive T-lymphocyte (CD4 cell) count trajectories

124 with 77 nonusers on age, race, and pre-HAART CD4-positive T-lymphocyte (CD4+ cell) count and viral lo

125 tested semiannually to identify their first CD4-positive T-lymphocyte cell count below 200/microl; t

126 equency of measurement of HIV RNA levels and CD4-positive T-lymphocyte cell counts introduce a possib

127 The annual CD4-positive T-lymphocyte cell decline was less in untre

128 e (p = 0.10), low hemoglobin (p = 0.11), and CD4-positive T-lymphocyte count (p = 0.04).

129 men and how this effect differs depending on CD4-positive T-lymphocyte count.

130 CD4-positive, T-cell-enriched PECs contained only a very

131 to protect against disorders with increased CD4-positive Th1 responses in animals.