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1 CLA and CNA significantly reduced body weight and fat ma
2 CLA and CNA significantly reduced serum leptin and tumou
3 CLA and OCS act non-additively to activate atNHE1, indic
4 CLA attenuated the increase in BMI (0.5 +/- 0.8) compare
5 CLA exerts its anti-carcinogenic effect by reducing VEGF
6 CLA expressed on CD43 was found exclusively on the high-
7 CLA has a wide range of biological effects, including bo
8 CLA significantly increased bone markers without major c
9 CLA supplementation for 7 +/- 0.5 mo decreased body fatn
10 CLA supplementation significantly prevented ovariectomy-
11 CLA treatment increased serum parathyroid hormone (PTH)
12 CLA was microencapsulated by spray drying in ten varied
13 CLA(+) is expressed on the surface of circulating CD45RO
14 CLA(+) TH2 T cells were markedly expanded in both childr
15 CLA+ and alpha4beta7+ memory T cells were isolated and c
16 CLA+ CD43 purified from human T cells supported tetherin
17 CLA-rich eggs and soy control eggs were produced by addi
18 CLA-yolk mayonnaise was more viscous, had greater storag
19 CLA/ESL mediates adhesion of T cells to inflamed vascula
20 CLA:M:PPC (1:1:3) microparticles demonstrated better mor
21 CLA:M:PPC (1:1:3) showed the most promising results, thu
22 had increased CLA(+) /CLA(-) Th2 (P < .007), CLA(+) Tc2 (P = .04), and CLA(+) Th22 (P < .05) frequenc
24 e members of the SR-B family, namely, CLA-1, CLA-2, and CD36, mediate recognition of bacteria not onl
27 soy control eggs were produced by adding 10% CLA-rich soy oil or 10% of control unmodified soy oil to
28 from mountain areas showed average c-9, t-11 CLA content higher than those from prairie districts.
29 ilk yogurts showed lower values of c-9, t-11 CLA content on lipid basis compared to full-fat yogurts.
30 roducts naturally enriched in cis-9,trans-11 CLA (and trans-11 18:1) on the blood lipid profile, the
31 dairy products enriched with cis-9,trans-11 CLA and trans-11 18:1 did not significantly affect body
32 ducts naturally enriched with cis-9,trans-11 CLA and trans-11 18:1 do not appear to have a significan
33 erse association between the cis-9, trans-11 CLA in adipose tissue and diabetes risk is consistent wi
39 The cis-9, trans-11 and trans-10, cis-12 CLA isomers in adipose tissue and 48 other fatty acids w
40 nflammatory proteins were increased by 10,12-CLA compared with bovine serum albumin vehicle in the ad
41 ns-10,cis-12-conjugated linoleic acid (10,12-CLA) activate the inflammatory signaling that promotes i
47 mory cell markers, CHO-131(+) and CHO-131(-) CLA(+) T cells have an overlapping skin-tropic and memor
48 inding capacity of CHO-131(+) and CHO-131(-) CLA(+) T cells revealed a significantly greater P-select
49 te supplementation in rodents elevates NO(2)-CLA levels in plasma, urine, and tissues, which in turn
50 erexpression abrogated cell surface HECA-452/CLA expression, reduced the number of rolling leukocytes
52 re randomly assigned to receive 3 g/d of 80% CLA (50:50 cis-9,trans-11 and trans-10,cis-12 isomers) o
53 with the phosphatase inhibitor calyculin-A (CLA) increase Na(+) transport capacity without affecting
55 imental studies on conjugated linoleic acid (CLA) and insulin regulation suggested that CLA could be
56 of 2 dietary oils, conjugated linoleic acid (CLA) and safflower oil (SAF), on body weight and composi
57 ch in trans, trans conjugated linoleic acid (CLA) are significantly more viscous, have more phospholi
60 n for the elderly; conjugated linoleic acid (CLA) has been shown to improve overall bone mass when ca
62 tes the effects of conjugated linoleic acid (CLA) in preventing bone loss, using an ovariectomised mo
63 Many studies with conjugated linoleic acid (CLA) indicate that it has a protective effect against ma
68 GC-FID), including conjugated linoleic acid (CLA) isomeric profile (Ag(+)-HPLC), and nutritional valu
69 identification of conjugated linoleic acid (CLA) isomers has been developed in which silver ion liqu
70 e development of a conjugated linoleic acid (CLA) oil-in-water beverage emulsion containing acacia gu
71 n the synthesis of conjugated linoleic acid (CLA) partial glycerides, which presented nutraceutical p
72 sity is to consume conjugated linoleic acid (CLA) supplements containing isomers cis-9, trans-11 and
74 ty acids including conjugated linoleic acid (CLA), polyunsaturated fatty acids C18:2(n-6) and C18:3(n
76 the main source of conjugated linoleic acid (CLA; 18:2n-7t), which is produced by the ruminal biohydr
80 ho were receiving either 4 g/d of 78% active CLA isomers (3.2 g/d: 39.2% cis-9,trans-11 and 38.5% tra
83 ed to as cutaneous lymphocyte-associated Ag (CLA) T cells) correlates with E-selectin binding, yet wh
87 uencies, which were highly significant among CLA(-) cells (IL-22: 3.7 vs 1.7 [P < .001] and IL-17: 1.
88 group than in the PCV group (P = .014); and CLA was expressed more frequently in the pneumonia group
91 l adhesion and cytosolic invasion, CLA-1 and CLA-2 may play an important role in infection and sepsis
92 and replicate intracellularly in CLA-1- and CLA-2-overexpressing HeLa, but both L-37pA and D-37pA pr
97 tin and CD27 but strongly expressed CCR4 and CLA, a phenotype suggestive of skin resident effector me
99 aneous lymphocyte antigen (CLA)-positive and CLA(-) T-cell subsets in patients with AD and control su
100 Cutaneous lymphocyte-associated antigen (CLA(+) ) T cells are specialized for skin homing and rep
101 hat cutaneous lymphocyte-associated antigen (CLA), a functional E-selectin ligand (ESL), is selective
102 med cutaneous lymphocyte-associated antigen (CLA), a skin-homing receptor, than do circulating HSV-sp
105 oming markers, cutaneous lymphocyte antigen (CLA) and alpha4beta7 integrin, are used to determine whe
108 -selectin, and cutaneous lymphocyte antigen (CLA) on S. pneumoniae-specific plasmablasts was examined
109 s positive for cutaneous lymphocyte antigen (CLA) were increased fourfold in all CD4+ and CD8+ T cell
111 rities between cutaneous lymphocyte antigen (CLA)(+) polarized T-cell subsets in children versus adul
112 contained few cutaneous lymphocyte antigen (CLA)(+) T cells, the cell type thought to provide cutane
113 CXCR3, but not cutaneous lymphocyte antigen (CLA), on circulating T cell subsets was associated with
114 ubsets in both cutaneous lymphocyte antigen (CLA)-positive and CLA(-) T-cell subsets in patients with
115 mir1-mediated resistance to corn leaf aphid (CLA; Rhopalosiphum maidis), a phloem sap-sucking insect
117 ng small interfering NFkappaB p65 attenuated CLA suppression of glucose transporter 4 and peroxisome
119 ain emphasized the divergent effects of both CLA isomers on different pathways, but also revealed a l
126 PTDM (N = 24), the frequency of circulating CLA(+) (skin-homing) Tregs was decreased (1.53% vs 3.99%
127 e latest advancements reached on circulating CLA(+) in AD and the great potential they harbor in unde
128 Isomerization of cis,trans and trans,cis CLA to trans,trans isomers was observed mainly for the m
129 e significantly higher in the trans10, cis12-CLA group, whereas plasma triglyceride, NEFA, glucose, a
130 rast, the treatment effect of trans10, cis12-CLA was mainly explained by up-regulation of key enzymes
131 of CLA, cis9, trans11-CLA and trans10, cis12-CLA, affected lipid and glucose metabolism, as well as h
133 the analysis of CLA isomers in a commercial CLA supplement, milk fat, and the lipid extract from a L
135 due to inflammatory signaling and considers CLA's linkage with lipogenesis, lipolysis, thermogenesis
137 djustment to the median dose of 3.2 g CLA/d, CLA was effective and produced a reduction in fat mass f
142 intravital microscopy, we show that, during CLA-induced regression of pre-established atherosclerosi
145 nzymatic and cellular mechanisms account for CLA nitration, including reactions catalyzed by mitochon
147 esented describe a novel functional role for CLA in the regulation of monocyte adhesion, polarization
148 itioned medium (CM) model, CM collected from CLA-treated AD50 but not AD0 cultures induced IL-8 and I
149 After adjustment to the median dose of 3.2 g CLA/d, CLA was effective and produced a reduction in fat
158 roliferation predominates in the skin-homing CLA+ subset, whilst peanut-tolerant groups have a mixed
159 aimed to compare frequencies of skin homing (CLA(+) ) vs systemic (CLA(-) ) "polar" CD4(+) and CD8(+)
160 tion markers and frequencies of skin-homing (CLA(+)) versus systemic (CLA(-)) "polar" CD4 and CD8 T-c
163 those in control subjects, but decreases in CLA(+) TH1 T-cell numbers were greater in children with
164 ke in adults, no imbalances were detected in CLA(-) T cells from pediatric patients with AD nor were
167 to survive and replicate intracellularly in CLA-1- and CLA-2-overexpressing HeLa, but both L-37pA an
168 ming growth factor beta are each involved in CLA expression by memory HSV type 2 (HSV-2)-specific CD4
169 sn-1 mono and sn-1,3 diacylglycerols rich in CLA, with a ratio of sn-1,3/sn-1,2 regioisomers of 21.8,
171 ly, use of bifidobacteria slightly increased CLA relative content in the conventional fermented milks
172 g bacterial adhesion and cytosolic invasion, CLA-1 and CLA-2 may play an important role in infection
174 oxidative stability of conjugated linoleic (CLA) and linoleic (LA) acids in different chemical forms
175 g cis-9 trans-11, C18:2 conjugated linoleic (CLA-1.4 times), and alpha-linolenic acids (ALA-1.6 times
183 at three members of the SR-B family, namely, CLA-1, CLA-2, and CD36, mediate recognition of bacteria
185 y, human serum albumin was found to bind NO2-CLA both non-covalently and to form covalent adducts at
186 presence of two electrophilic centers in NO2-CLA located on the beta- and delta-carbons with respect
188 this work, we examined the reactions of NO2-CLA with low molecular weight thiols (glutathione, cyste
192 n (+/-SD) percentage of total fatty acids of CLA for the cis-9, trans-11 isomer in adipose tissue was
193 the study was to test whether the amount of CLA in adipose tissue is associated with risk of diabete
194 /O3-MS method was applied to the analysis of CLA isomers in a commercial CLA supplement, milk fat, an
196 tives were (1) compare the FA composition of CLA-rich yolk granules and plasma, relative to standard
199 sed for the direct and fast determination of CLA isomers at low concentrations and in complex lipid m
201 to demonstrate the anti-angiogenic effect of CLA in the brain, and suggests that CLA be explored as a
202 This comparison indicated that the effect of CLA was linear for up to 6 mo and then slowly approached
206 ing in the skin, and thus, the evaluation of CLA(+) T cells in the blood may eliminate the need for s
209 s develop strong and selective expression of CLA and E-selectin ligand while responding to HSV antige
215 in resident T cells expressed high levels of CLA, CCR4, and CCR6, and a subset expressed CCR8 and CXC
217 ation were measured before and after 6 mo of CLA supplementation by using whole-room indirect calorim
219 had higher Bet v 1-specific proliferation of CLA(+) and CCR4(+) T cells compared with patients with b
220 ility (CLA isomer profile, quantification of CLA and volatile compounds by SPME coupled with CG-MS) d
221 E-selectin on tumor vessels, recruitment of CLA(+) CD8(+) T cells, and histological evidence of tumo
222 ts are the most important dietary sources of CLA, we have investigated the CLA concentrations and add
224 did not influence the oxidative stability of CLA, however its presence improved physical-chemical cha
227 d, double-blind, placebo-controlled trial of CLA in 62 prepubertal children aged 6-10 y who were over
230 l women with type 2 diabetes received SAF or CLA (8 g oil/d) during two 16-wk diet periods separated
231 < .0001), and frequencies of IL-13-producing CLA(+) cells were also correlated with IgE levels and SC
233 ocytes and dendritic cells from PBMC reduces CLA expression by HSV-2-responsive CD4 lymphoblasts, whi
236 here were no differences in Bet v 1-specific CLA(+) and CCR4(+) proliferation and cytokine secretion
237 state of PA correlates with peanut-specific CLA responses, with tolerance associated with predominan
238 cal characteristics and oxidative stability (CLA isomer profile, quantification of CLA and volatile c
240 cts of the addition of CPP on the structure, CLA, and cell transduction properties of alphaB-crystall
242 ies of skin-homing (CLA(+)) versus systemic (CLA(-)) "polar" CD4 and CD8 T-cell subsets in patients w
243 encies of skin homing (CLA(+) ) vs systemic (CLA(-) ) "polar" CD4(+) and CD8(+) and activated T-cell
245 and cell studies suggest that VA and c9,t11-CLA may be hypocholesterolemic and antiatherogenic, epid
247 We determined the effects of VA, c9,t11-CLA, and iTFA, in the context of highly controlled diets
248 , with the requirement of VA, but not c9,t11-CLA, to be listed under TFA on the Nutrition Facts Panel
252 tic-adhesion assay, we provide evidence that CLA prevents monocytes from binding to ICAM-1 and subseq
258 (CLA) and insulin regulation suggested that CLA could be associated with risk of diabetes, but epide
259 ffect of CLA in the brain, and suggests that CLA be explored as a therapeutic treatment for cancer an
262 in the change in fat utilization between the CLA (4 +/- 8 g) and placebo (-7 +/- 11 g) groups during
263 However, feeding regimens that enhance the CLA content of milk also increase concentrations of tran
264 and produced a reduction in fat mass for the CLA group alone (0.05 +/- 0.05 kg/wk; P<0.001) and for t
265 e (0.05 +/- 0.05 kg/wk; P<0.001) and for the CLA group compared with placebo (0.09 +/- 0.08 kg/wk; P<
266 al body weight was smaller (P = 0.02) in the CLA group (-0.09 +/- 0.9%) than in the placebo group (0.
267 bsorptiometry was smaller (P = 0.001) in the CLA group (-0.5 +/- 2.1%) than in the placebo group (1.3
268 creased significantly more (P = 0.05) in the CLA group (-5.1 +/- 7.3 mg/dL) than in the placebo group
269 ineral accretion was lower (P = 0.04) in the CLA group (0.05 +/- 0.03 kg) than in the placebo group (
270 from protein was reduced during sleep in the CLA group (CLA: -3.3 +/- 2.6%; placebo: 0.3 +/- 5.7%).
272 ary sources of CLA, we have investigated the CLA concentrations and additionally the fatty acid profi
273 skin-resident T cells, while maintaining the CLA(+)CCR4(+) skin-homing phenotype as well as a diverse
274 The physical-chemical properties of the CLA microparticles were characterised by core retention,
280 eters aphid settling)-mediated resistance to CLA compared with B73 and Tx601 maize susceptible inbred
285 plored how two isomers of CLA, cis9, trans11-CLA and trans10, cis12-CLA, affected lipid and glucose m
286 ere significantly lower in the cis9, trans11-CLA group, compared with control mice consuming linoleic
288 I analog 1, CLA-1, and its splicing variant, CLA-2 (SR-BI and SR-BII in rodents), are human high dens
289 ace method was used and 10% w/w AG, 3.5% w/w CLA and 0.3% w/w XG was introduced as the optimum formul
290 l properties are needed to establish whether CLA(+) memory subsets can be used as biomarkers and a su
292 ll characterized, it remains unknown whether CLA also affects vascular morphology in the central nerv
293 is a meta-analysis of human studies in which CLA was provided as a dietary supplement to test its eff
294 esulting search to identify studies in which CLA was provided to humans in randomized, double-blinded
296 Understanding the mechanisms through which CLA mediates its atheroprotective effect may help to ide
297 gical properties of mayonnaise prepared with CLA-rich eggs to control eggs and (3) compare the emulsi
300 aegypti mosquitoes infected with the wMelPop-CLA strain of Wolbachia and in Drosophila melanogaster a
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