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1 CN is performed in three of 10 patients with mRCC who ar
2 CN is the key mediator of cellular responses to Ca(2+) s
3 CN neuron progenitors are produced in the mutant but the
4 tivity relationships established that the 1'-CN group and C-linked nucleobase were critical for optim
6 ntioselectivity and differing results in (13)CN crossover experiments, initial rate kinetics, and nat
8 ss toxic heavy metal and the reagent [(13/14)CN]-NCTS is a stable, easy-to-handle crystalline solid t
10 Conversion of the complex to poly-Fe(vbpy)2(CN)2 followed by surface binding of salts of the cations
11 -)OTf (Stang's reagent) or 3,5-(CF3)2C6H3I(+)CN(-)OTf to afford naphthyl(aryl)iodonium triflates.
13 nprecedented f-block MIC complexes [M(N'')3 {CN(Me)C(Me)N(Me)CH}] (M=U, Y, La, Nd; N''=N(SiMe3 )2 ) a
14 "H-cluster"), which consists of a [Fe2(CO)3(CN)2(dithiomethylamine)] subcluster covalently attached
15 c radical that undergoes asymmetric C(sp(3))-CN bond formation upon reaction with a chiral copper cat
16 s(-1) and N-H BDE = 77.4 kcal mol(-1) for 3-CN,7-NO2-phenoxazine to kinh = 6.6 x 10(8) M(-1) s(-1) a
18 f the aryl substitution then identified a 4'-CN group that improved the human/rodent correlation in m
19 015) and 11,381 individuals (5,728 AD, 5,653 CN controls) from the Alzheimer's Disease Genetics Conso
25 rovement in vestibulomotor performance after CN-105 treatment, as quantified by increased Rotarod lat
27 a- and tetra-CNs (predominantly CN-52/60 and CN-42) dominated the PCN profile, the hexa-CNs (mainly C
28 sured for Z = OAc, NPhth, CO2Me, Cl, Br, and CN, indicative of alpha-CH2 deactivation with HAT that p
29 cysteine to a [2Fe] complex carrying CO and CN(-) ligands as well as a bridging aza-dithiolate ligan
30 for the synthesis of the hydrogenase CO and CN(-) ligands from tyrosine-derived dehydroglycine (DHG)
32 marked variations in F- and L- genotypes and CN among the various ethnic groups that may impact HV1-6
35 ms are functionally active for N2-to-NH3 and CN-to-CH4/NH3 conversion, respectively, when subjected t
39 coupling small nucleophiles (-OH, -NH2, and -CN) and multiple functional groups onto the boron-rich c
40 The 6-coordinate heme Fe(III)-OH(-) and -CN(-) complexes of AfGcHK are also active, but the 5-coo
41 y up to one order of magnitude for an apical CN(-) at the distal iron ion of the cofactor as opposed
48 gether, the results implicate the astrocytic CN/NFAT4 pathway as a key mechanism for disrupting synap
49 nd propose a bonding scheme consisting of Au-CN and Au-NC bound molecules that are oriented normal to
51 For example, dodecacyanododecaborate, B12 (CN)12 (2-) , created by substituting H by CN is found to
52 on-precise hexacyanodiborane(6) dianion, [B2(CN)6](2-), were obtained using (11)B double-quantum-filt
53 )B,(11)B) coupling constants for various [B2(CN)6](2-) salts were measured to range from 29.4 to 35.8
54 s demonstrated in the gas phase, with BeB11 (CN)12(3-) exhibiting colossal stability against electron
55 in situ trypsinolysis and elution of B beta-CN(f1-25)4P and WB beta-CN(f1-28)4P proteotypic peptides
57 occurring in the ERM as being due to WB beta-CN(f100-209), which is also formed after plasminolysis o
63 2 (CN)12 (2-) , created by substituting H by CN is found to be highly stable with the second electron
64 y aspects of the mechanism of Pd-catalyzed C-CN bond activation and intramolecular enantioselective a
65 e, we show that a highly active calcineurin (CN) phosphatase fragment and its substrate transcription
66 ysis of the protein phosphatase calcineurin (CN) and the elevated expression of the CN-dependent tran
67 sing evidence suggests that the calcineurin (CN)-dependent transcription factor NFAT (Nuclear Factor
68 (WPI), soy protein isolate (SPI) and casein (CN) and their binary mixtures, viz., WPI+SPI, WPI+CN and
69 ns, beta-lactoglobulin (beta-LG) and casein (CN) was greatly diminished with gastric simulation (0-60
70 ally important is the observation that CB11 (CN)12 (2-) , which contains one electron more than neede
73 The sluggish oxidants [Fe(IV) (O)(TMC)(CH3 CN)](2+) (TMC=1,4,8,11-tetramethyl-1,4,8,11-tetraazacycl
74 ocedure based on loading of B/WB milk/cheese CN extracts on a hydroxyapatite column, in situ trypsino
75 the processing additives 1-chloronapthalene (CN), diphenylether (DPE), and 1,8-diiodooctane (DIO), re
77 direction, where elongation of the axial Co-CN bond and Co-NIm bond on a 110 fs time scale is follow
78 -selective isotope editing to monitor the CO/CN(-) stretching vibrations in [FeFe]-hydrogenase HYDA1
79 hat 20% of PC inputs to a full compartmental CN neuron model need to be rate-comodulated for transmis
80 ives rise to an unprecedented 16-coordinate (CN 16) Cs(+) cation in a likewise unprecedented tetracos
81 t in addition to other available covariates, CN patients had a lower risk of any death (hazard ratio,
84 s, but became markedly activated by cyanide (CN) or the known opener P1075 with a current density tha
85 and successfully applied to detect cyanide (CN(-)) based on a Michael-type nucleophilic addition rea
87 incorporated carbon-deuterium (C-D), cyano (CN), thiocyanate (SCN), and azide (N3) "transparent wind
88 The crystal structure of the [CYP121(cYY)CN] ternary complex showed a rearrangement of the substr
90 ime-resolved spectrometry, we have detected .CN radical and excited CO as the initially most abundant
91 mpared to the same plasmid DNA loaded in DNA-CN in two aggressive orthotopic brain tumor models in ra
95 NA-loaded conventional nanocomplexes, or DNA-CN), and transgene expression reached beyond the tumor e
96 ional and rotational cooling of an energetic CN radical can be observed directly using ultrafast tran
98 lls, the electron-transfer resistance of Fe (CN)6(3-/4-) redox couple increased considerably on the a
100 y signal of a redox probe ([Fe(CN)6](3-)/[Fe(CN)6](4-)) that is altered upon binding of PSMA with PSM
101 CH2OH, cationic Ru(NH3)6(3+), and anionic Fe(CN)6(4-)) in a phosphate buffer solution (PBS) containin
102 ng in presence of the negatively charged [Fe(CN)6](3-/4-) indicates the lowest DNA detection limit of
104 he electrochemical reaction impedance for Fe(CN)6(3-/4-) on oligonucleotide-modified electrodes showe
105 n a convection-enhanced rate constant for Fe(CN)6(4-) oxidation of 1.4 x 10(-4) m s(-1), which is the
106 ble voltammetric behavior is obtained for Fe(CN)6](3-/4-); after a CPT, this was attained even when t
107 latively positive formal potential (e.g., Fe(CN)6(3/4-)) were added to the solution and increased upo
110 reduction of a potassium ferrocyanide (K4[Fe(CN)6].3H2O) were measured and shown to compare favorably
111 um Prussian white analogue, (NH4 )1.47 Ni[Fe(CN)6 ]0.88 , as the cathode, an organic solid, 3,4,9,10-
112 ction process was based on the ability of Fe(CN)6(3-) to oxidize DHEThDP to glycolic acid along with
113 ectrochemical studies in the presence of [Fe(CN)6](3-/4-) indicate that the presence of both DOPE and
114 sed spectroelectrochemical modulation of [Fe(CN)6](3-/4-) was demonstrated, as well as the fluorescen
116 lse voltammetry signal of a redox probe ([Fe(CN)6](3-)/[Fe(CN)6](4-)) that is altered upon binding of
119 y doped BDD electrode, assessed with the [Fe(CN)6](3-/4-) and AA redox probes, and on the atomic bond
120 on transfer resistance (Ret) between the [Fe(CN)6](3-/4-) redox probe in the solution and the substra
121 For instance, on an HT-BDD electrode the [Fe(CN)6](3-/4-) redox system presents a reversible voltamme
122 d to assess outer-sphere charge transfer (Fe(CN)6(4-)) and organic compound oxidation through both di
124 from the direct protonation of Fe-N2 and Fe-CN species at the terminal N atom (e.g., Fe horizontal l
129 high) is an adverse prognostic biomarker for CN-AML, which may be attributed to the distinctive genom
132 ical signature regions distinguished AD from CN participants (area under the receiver operating chara
133 Sulfonation of graphitic carbon nitride (g-CN) affords a polar and strongly acidic catalyst, Sg-CN,
134 urrent than bulk graphitic carbon nitride (G-CN) photoanode, with a record photocurrent density of 10
137 turing two inequivalent Rb(+) cations having CN 10, one of which involves Rb(+)(eta(2)-Cl2CH2)2 coord
138 )2.2.5 H2O (copper nitrate hemipentahydrate, CN), an alternating Heisenberg antiferromagnetic chain m
141 O framework scaffold, [Fe(II)(bztrz)2(Pd(II)(CN)4)].n(guest) (bztrz = (E)-1-phenyl-N-(1,2,4-triazol-4
142 dimeric globin domains of the active Fe(III)-CN(-) and inactive 5-coordinate Fe(II) forms, revealing
143 FRET sensors, we hypothesized that impaired CN regulation provides a direct link to abnormal signali
144 g parallel= 2.31, g perpendicular = 2.14 in CN, with which the magnetothermal properties have been f
147 estigated the magnetocaloric effect (MCE) in CN by calculating its isentropes and magnetic Gruneisen
150 reveal explicitly the spin chain scenario in CN by displaying the calculated electron density distrib
151 nts for the high coefficient of variation in CN spike trains, while the balance between excitation an
152 or of the membrane decreases with increasing CN(-) concentration, which can be easily observed with t
153 e to assign the IR signals of the individual CN(-) ligands of the (2FeH) site for different redox sta
156 KIF1Bbeta actuates recognition of all known CN substrates, implying a general mechanism for KIF1Bbet
158 in a lower second-order rate constant (kon (CN)) but a much more stable cyanide adduct with 3 orders
159 Here we propose a cyanoperovskite KxMnFe(CN)6 (0 </= x </= 2) as a potassium cathode: high-spin M
160 raphically characterized analog (Et4N)2[Co(L)CN], (Et4N)2[2], gives insight into the structure of [3]
162 nces between LDL-CD and estimated LDL-C (LDL-CN or LDL-CF) was stratified by LDL-C and triglyceride c
163 The novel method of LDL-C estimation (LDL-CN) uses a flexible approach to derive patient-specific
165 200 to 399 mg/dL in nonfasting patients, LDL-CN <70 mg/dL accuracy (82%) was superior to LDL-CF (37%;
167 togenetically normal acute myeloid leukemia (CN-AML) patients (aged <60 years) based on several micro
168 ryls to afford a bidentate chelating ligand (CN(tBu)Ar3NC) that is able to stabilize chromium in its
169 erical F(-) and Cl(-) anions, and the linear CN(-) (log Kass = 3.46, 3.50, and 4.02, respectively).
171 of Prussian blue analogues (C3 H5 N2 )2 K[M(CN)6 ], where C3 H5 N2 is the imidazolium ion and M=Fe,
173 inated the PCN profile, the hexa-CNs (mainly CN-66/67) accounted for the majority of the Sigma67TEQ-P
176 CVD associated with a 1-SD decrease in mtDNA-CN were 1.29 (95% CI, 1.24-1.33), 1.11 (95% CI, 1.06-1.1
180 n films of bacterial cellulose nanocrystals (CN) to provide a more sensitive and adapted interface fo
181 duced DOPA-melanin, Cryptococcus neoformans (CN); and the slow-growing environmental rock-inhabiting
185 in the long term (2100): the carbon neutral (CN) lever to achieve zero net emissions of CO2, the supe
186 posed of a large subunit that harbors a NiFe(CN)2CO metallo-center and a small subunit with three iro
187 included formation and insertion of the NiFe(CN)2CO cofactor into the large subunit, endoproteolytic
188 cy generation (VSFG) results of the nitrile (CN) stretch of 4-mercaptobenzonitrile (4-MBN) covalently
190 substantial proportion of clinically normal (CN) older individuals are classified as having suspected
191 59 participants who were cognitively normal (CN) (Clinical Dementia Rating [CDR] score, 0) or had AD
195 ut dementia, including a cognitively normal (CN) subsample of 144 adults, enrolled in the Ginkgo Eval
196 individuals (191 AD, 118 cognitively normal [CN] controls) from the San Francisco-based University of
197 , we develop a strategy termed cell-nuclear (CN) correlation to parameterize represented dynamic subc
198 cell-specific markers of cerebellar nuclear (CN) neurons and unipolar brush cells (UBCs), respectivel
199 l glutamatergic neurons [cerebellar nuclear (CN) neurons, granule cells, and unipolar brush cells (UB
200 he Purkinje cell (PC) to cerebellar nucleus (CN) pathway in a modeling study using a data set recorde
201 (ScNs) and mouse auditory cochlear nucleus (CN) neurons to understand whether ScNs of the peripheral
203 found that a high Au-S coordination number (CN) and a high surface coverage resulted in strong Au(I)
204 expression through promoter and copy number (CN) variations has not been reported, nor has whether IG
206 significant alterations in DNA copy numbers (CN), gene expression levels, and DNA methylation profile
210 to investigating the possible association of CN with insecticide resistance, three assays were compar
214 d CoOxH-GO probe for the visual detection of CN(-) by preparing a thin film of CoOxH-GO on a positive
217 ty and reusability of 1 for the detection of CN(-) ion was also tested for five cycles indicating the
218 ogenous doping and anisotropic dispersion of CN nanospheres along the entire NB head nanotubes lead t
224 is seriously damaged due to the presence of CN(-) ions, which are released from the ferri/ferrocyani
226 o evaluate contemporary utilization rates of CN and to examine the survival benefit of CN compared wi
229 sed to facilitate the catalytic reduction of CN(-) , CO, and CO2 into hydrocarbons in the isolated st
231 Here we describe the crystal structure of CN in complex with its substrate NFATc1 and show that th
234 We concluded, therefore, that pentapeptide CN-105 improved short- and long-term neurobehavioral out
235 efore, we developed a 5-amino acid peptide - CN-105 - that mimics the polar face of the apoE helical
236 ed a small 5 amino acid apoE mimetic peptide(CN-105) that mimics the polar face of the apoE helical d
237 argylic or homopropargylic, react with PhI(+)CN(-)OTf (Stang's reagent) or 3,5-(CF3)2C6H3I(+)CN(-)OTf
238 ulted in the identification of 567 potential CN substrates; a small subset was experimentally confirm
239 ough the penta- and tetra-CNs (predominantly CN-52/60 and CN-42) dominated the PCN profile, the hexa-
241 econdary coordination sphere of the proximal CN(-) ligand (i.e., closest to the (4FeH) site) can affe
242 spin-crossover properties of the {Fe(pz)[Pt(CN)4]} metal-organic framework upon water adsorption.
243 the spin-crossover temperature of {Fe(pz)[Pt(CN)4]} upon water adsorption predicted by the simulation
245 ion, and 600 nm emission, whereas a low Au-S CN and a low surface coverage led to weak charge transfe
246 rds a polar and strongly acidic catalyst, Sg-CN, which displays unprecedented reactivity and selectiv
248 nary mixtures, viz., WPI+SPI, WPI+CN and SPI+CN, were produced using transglutaminase, and their in v
251 oOxH-GO/N(+)M operates on the principle that CN(-) inhibits the catalytic activity of CoOxH-GO toward
259 Images of iconic buildings, such as the CN Tower, instantly transport us to specific places, suc
260 for regioselective syn-addition of both the CN and OTf groups of aryl(cyano)iodonium triflates to al
261 rovides a powerful method for dissecting the CN interaction network and for elucidating the role of C
264 Based on the biophysical meaning of the CN correlation, we propose a cell migration potential in
265 l successfully explains the red-shift of the CN stretch as a function of the dielectric constant and
266 A blue shift to higher frequencies of the CN vibration to 2235 cm(-1) with respect to the as-adsor
267 ld be due to the more structural role of the CN(-) ligands tightly anchoring the (2FeH) unit to the p
268 urin (CN) and the elevated expression of the CN-dependent transcription factor nuclear factor of acti
270 ring during the catalytic cycle, whereas the CN(-) signals seem to be relatively inert to these effec
271 Bbeta affects mitochondrial dynamics through CN-dependent dephosphorylation of Dynamin-related protei
272 functional theory calculations show that Ti3 CN is metallic, in contrast to other 2D saturable absorb
275 The hydrogen atom transfers from the CH3 to CN along the CHN hydrogen bond, which produces an amino
277 dination sphere composed of three CO and two CN(-) ligands affecting its redox properties and providi
280 ve been developed; univariate analysis using CN emission band and multivariate calibration NN model o
281 evelop field-applicable diagnostics for Vgsc CN, and as a prelude to investigating the possible assoc
282 d-curve yielded similar predictions for Vgsc CN, indicating that the qPCR protocol developed here can
283 ostic assay, facilitating monitoring of Vgsc CN in wild populations and the elucidation of associatio
286 ed green fluorescent protein (EGFP), whereas CN neurons were from postnatal mouse primary cultures.
292 overall pattern in AML, those patients with CN-AML have a poorer survival rate when GFI1 expression
295 g the (1)p* state by an electron-withdrawing CN substituent at the ortho or para position could slow
296 with a wide range of whey protein:casein (WP:CN) ratios (with standardised casein concentrations) wer
297 nd their binary mixtures, viz., WPI+SPI, WPI+CN and SPI+CN, were produced using transglutaminase, and
300 ubstantially switch thermal expansion of YFe(CN)6 from negative (alphav =-33.67x10(-6) K(-1) ) to pos
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