ライフサイエンスコーパス: CNP

1 CNP (C-type natriuretic peptide) inhibits myofibrogenesi

2 CNP also exhibited modest survival-promoting effects for

3 CNP and (Cys18)-atrial natriuretic factor (4-23) amide (

4 CNP and cANF(4-23) reduced infarct size after 25 minutes

5 CNP binds to the structural protein Gag and blocks HIV-1

6 CNP has previously been implicated in the regulation of

7 CNP is also widespread in the Plasmodium falciparum geno

8 CNP's outstanding properties in biosensors which go from

9 CNP-cre:TNFR2(fl/fl) mice with TNFR2 ablation in oligode

10 CNP-induced sensitization of TRPV1 activity was attenuat

11 CNP-Sox17 mice showed increased Gli2 protein levels and

12 CNP/dnIRF-1 mice exhibited no phenotypic abnormalities b

13 CNPs are defined by the cognitive function they extract,

14 CNPs can be used as a whole sensor or a part of recognit

15 CNPs of various size are designed by tweaking size (2-25

16 CNPs that exhibit mostly or exclusively PL arising from

17 CNPs upstream of the urate transporter SLC2A9 on chromos

18 On average, individuals differed by 11 CNPs, and the average length of a CNP interval was 465 k

19 o successfully obtain CNP genotypes for 1495 CNPs from 487 human DNA samples of diverse ethnic backgr

20 ion range 8.5x10(-6) to 1.9x10(-9)molL(-1) 2-CNP with a correlation coefficient of (0.999) and a dete

21 ex at 457nm by the 2-chloro-4-nitrophenol (2-CNP) which produced from the reaction of the enzyme with

22 el matrix by various concentrations of the 2-CNP was successfully used as an optical sensor for the a

23 ered by 11 CNPs, and the average length of a CNP interval was 465 kilobases.

24 Pyrolysis at 180 degrees C leads to a CNP molecular precursor with a strongly intense photolum

25 rential charging (zeta-potential) of the AC, CNPs, and SWNTs that comes about during the chemical pro

26 pharmacological activity of a 39 amino acid CNP analog (BMN 111) with an extended plasma half-life d

27 While lacking renal actions, CNP is less hypotensive than the cardiac peptides atrial

28 corresponding to known and novel additional CNPs were also observed.

29 alpha-carboxy nucleoside phosphonate (alpha-CNP), was designed that is recognized by a variety of po

30 particular, the carboxyl oxygen of the alpha-CNP acts as the potential equivalent of the alpha-phosph

31 xygens of the phosphonate group of the alpha-CNP chelate Mg(2+), mimicking the chelation by the beta-

32 alpha-CNPs (i) do not require metabolic activation (phosphoryl

33 alpha-CNPs represent an entirely novel and broad technological

34 the kinetic interaction of the acyclic alpha-CNPs against the herpetic DNA polymerases differs from t

35 In addition, alpha-CNPs were also found to selectively interact with regula

36 kinetic interaction of the cyclopentyl alpha-CNPs against HIV RT.

37 for the synthesis of a series of novel alpha-CNPs, including a Rh(II)-catalyzed O-H insertion that co

38 Alpha-carboxynucleoside phosphonates (alpha-CNPs) are novel viral DNA polymerase inhibitors that do

39 alpha-carboxy nucleoside phosphonates (alpha-CNPs).

40 he cyclopentyl moiety in the prototype alpha-CNPs by a more flexible entity results in a selectivity

41 -1 reverse transcriptase revealed that alpha-CNPs mimic the dNTP binding through a carboxylate oxygen

42 Here we propose a novel method to analyse CNP using spatial statistical modelling.

43 he stimulation of NPR-A and NPR-B by ANP and CNP, respectively.

44 IDE rapidly cleaves ANP and CNP, thus inactivating their ability to raise intracellu

45 genes that participate in PTHrP-IHH, BMP and CNP signaling, and many genes that have not previously b

46 nd NPR-B to the stimulation of ANP, BNP, and CNP in cultured cells.

47 Three distinct NPs (ANP, BNP, and CNP) can selectively activate natriuretic peptide recept

48 eactivity for all NP hormones (ANP, BNP, and CNP), in contrast to other NPRs, which are more restrict

49 Phosphorylated p38MAPK was found in CC1- and CNP-expressing differentiated oligodendrocytes of the ad

50 Both NO and CNP stimulate the synthesis of cGMP and thus the activat

51 primate lentiviruses are CNP-sensitive, and CNP sensitivity/resistance is determined by a single, na

52 NP regression models and the phasing SNP and CNP haplotypes (chi2df2=3190,p=7.23x10-08).

53 ported SNPs in SLC2A9 as assessed by SNP and CNP regression models and the phasing SNP and CNP haplot

54 y was downregulated in Npr2(+/-) valves, and CNP triggered synthesis of cGMP and activation of cGK1 (

55 Several primate lentiviruses are CNP-sensitive, and CNP sensitivity/resistance is determi

56 PEGylated CNPs is compared to those of bare CNPs, and the differences are outlined.

57 A negatively charged uncoated, "bare" CNP with high luminescence loses its PL when positively

58 Although biallelic CNPs show a strong correlation of copy number with flank

59 nique regions (p = 0.015) and that biallelic CNPs show greater stratification when compared to freque

60 (CNP, 100%, versus MHT, 98%; P = 0.08), but CNP was more specific (100% versus 80%; P < 0.0001) and

61 V1 as a novel signaling cascade recruited by CNP in mouse DRG neurons that can lead to enhanced nocic

62 ctive oxygen species (ROS) were generated by CNPs.

63 e assessed the global alterations induced by CNPs in A549 lung cells using biospectroscopy techniques

64 es, with the previous structure of the NPR-C/CNP complex, reveals that NPR-C uses a conformationally

65 rst-order, microbial implicit approach (CASA-CNP), and two recently developed microbially explicit mo

66 n cultured porcine valve interstitial cells, CNP inhibited pathological differentiation via the guany

67 This is the first study to characterize CNPs in ARIC and the first genome-wide analysis of CNPs

68 Similarly, negatively charged CNPs with hydroxyl and carboxylic functionalities did no

69 arable to those caused by positively charged CNPs.

70 cal needs are high-resolution maps of common CNPs and techniques that accurately determine the alleli

71 ween pairs of individuals were due to common CNPs with an allele frequency >5%, and more than 99% der

72 Sensitivities were comparable (CNP, 100%, versus MHT, 98%; P = 0.08), but CNP was more

73 This microarray contained CNPs in segmental duplication-rich regions and insertion

74 is study is to determine whether a deficient CNP signaling axis in mice causes accelerated progressio

75 to examine the valvular effects of deficient CNP/NPR2 signaling in vivo, in the context of both moder

76 Endothelium-derived CNP is involved in the regulation of the coronary circul

77 The high quantum yield of derived CNPs made them suitable for patterning and staining (flu

78 l of biospectroscopy techniques to determine CNP-induced alterations in target mammalian cells at ppb

79 Most common, diallelic CNPs were in strong linkage disequilibrium with SNPs, an

80 we have studied the effect of five different CNPs on a model relevant aquatic microorganism.

81 the feasibility of imputing newly discovered CNPs and SNPs.

82 Herein, DOX-encapsulated CNPs (DOX-CNPs) or Bcl-2 siRNA-encapsulated CNPs (siRNA-CNPs) exhi

83 iomarkers of cell alteration induced by each CNP type were identified.

84 Herein, DOX-encapsulated CNPs (DOX-CNPs) or Bcl-2 siRNA-encapsulated CNPs (siRNA-

85 CNPs (DOX-CNPs) or Bcl-2 siRNA-encapsulated CNPs (siRNA-CNPs) exhibited similar physicochemical prop

86 Our data establish CNP/NPR2 signaling as a novel regulator of aortic valve

87 Almost without exception, CNPs were not confined to a single population, suggestin

88 eurial arterioles express CNP, and exogenous CNP causes a concentration-dependent vascular relaxation

89 Epineurial arterioles express CNP, and exogenous CNP causes a concentration-dependent

90 ion, 2) GC-B phosphorylation is required for CNP-dependent activation by the A488P mutation, 3) the R

91 l cortical signals and their application for CNPs, including intention, motor imagery, decision makin

92 ical cohorts, the use of SNPs as markers for CNPs and statistical challenges in testing CNVs for asso

93 ogen peroxide and demonstrate an enzyme-free CNP-based biosensor capable of ultra-low (limit of quant

94 t, the R655C mutation converted GC-B-7A from CNP-unresponsive to CNP-responsive.

95 Furthermore, CNP injection into mouse hindpaw led to the development

96 f-function allele of a myelin-specific gene (CNP rs2070106-AA) associated with catatonia in 2 indepen

97 l study of CNVs, the challenge of genotyping CNPs in clinical cohorts, the use of SNPs as markers for

98 Neurofibroma number increased in homozygous CNP-hEGFR mice versus heterozygous littermates, and neur

99 amino acid difference in murine versus human CNP determines Gag binding and antiviral activity.

100 In CNP-Cre;Cdk5(fl/fl) conditional knock-out mouse (Cdk5 cK

101 In CNP-EGFP-positive (CNP-EGFP+) cells, Sox17 mRNA and prot

102 functional remyelination were accelerated in CNP-hEGFR mice compared with wild-type mice.

103 Sox17 overexpression in CNP-Sox17 mice sequentially promoted postnatal oligodend

104 supports the origin of photoluminescence in CNP as a surface phenomenon correlated a function of cha

105 improved by the solTNF inhibitor XPro1595 in CNP-cre:TNFR2(fl/fl) mice, indicating that for tmTNF to

106 Mice encode an inactive CNP variant and a single amino acid difference in murine

107 These include CNPs that are likely to be under positive selection, mos

108 We inferred a total of 2658 independent CNPs, 56% of which overlap genes.

109 study, we generated a transgenic mouse line (CNP/dnIRF-1) that overexpresses the dominant-negative fo

110 ntify a biological characteristic of macular CNP in malaria that had previously only been described s

111 igodendrocytes that expressed myelin markers CNP and Tmem10/Opalin.

112 Sox10), and mature oligodendrocyte markers (CNP, MBP) were quantified.

113 operties of MF-CNPs (smooth surfaces) and MF-CNP aggregations were characterized (RLCA aggregation of

114 xtraction and visualization of individual MF-CNPs that are mainly composed of high melting triacylgly

115 on of milk fat-crystalline nanoplatelets (MF-CNPs).

116 er-Porod models, structural properties of MF-CNPs (smooth surfaces) and MF-CNP aggregations were char

117 Elucidation of MF-CNPs provides a new dimension of analysis for describing

118 s were characterized (RLCA aggregation of MF-CNPs to form larger structures that present diffused sur

119 y image analysis, the length and width of MF-CNPs were measured (600 nm x 200 nm-900 nm x 300 nm).

120 stalline domain size, (i.e., thickness of MF-CNPs), was determined (27 nm (d001)).

121 Moreover, CNP, alone and in combination with sonic hedgehog (Shh),

122 ing SNP genotypes, the majority of multicopy CNPs do not (40% with r > 0.8).

123 Cerium oxide nanoparticles (nanoceria; CNPs) have been found to have both pro-oxidant and anti-

124 toluminescence (PL) of carbon nanoparticles (CNP) can be achieved with counterionic macromolecular ca

125 fective in sedimenting carbon nanoparticles (CNP), while leaving the SWNTs suspended in aqueous media

126 any manufactured carbon-based nanoparticles (CNPs) into our environment, generating a debate into the

127 t, glycol chitosan (GC)-based nanoparticles (CNPs) serve as an effective platform vehicle that can en

128 stem, especially carbon-based nanoparticles (CNPs).

129 ation mechanism of carbogenic nanoparticles (CNPs), otherwise referred to as C-dots, by following the

130 atom-doped fluorescent carbon nanoparticles (CNPs) by a unique combination of sonochemical, microwave

131 ic processing of carbonaceous nanoparticles (CNPs) may play an important role in determining their fa

132 Ceria nanoparticles (CNPs) have been demonstrated to neutralize free radical

133 Cerium oxide nanoparticles (CNPs) contain several properties such as catalytic activ

134 ect synthesis of cerium oxide nanoparticles (CNPs) in polyethylene glycol (PEG) based solutions with

135 ity of carbon based spherical nanoparticles (CNPs) through defined chemistry and a vigilant choice of

136 nd, in the culture of embryonic DRG neurons, CNP stimulates branch formation, induces axon outgrowth,

137 On E14.5, new CNP signals were observed in the ventrolateral spinal co

138 escence-activated cell-sorting-purified NG2+/CNP-EGFP+ or NG2+/beta-actin-enhanced yellow fluorescent

139 knowledge of the roles and mechanisms of NO, CNP and cGKII signaling in cartilage and endochondral bo

140 Comparisons of coding and noncoding CNPs, however, reveal a strong effect of purifying selec

141 (21.6 disc areas) of capillary nonperfusion (CNP) who were followed for 18 months before the availabi

142 For FLAG-NPR-C, neither ANP, BNP, nor CNP increased its internalization in either cell line.

143 First, the C-type NP (CNP) is expressed in a restricted area of the dorsal spi

144 aqueous conditions, and glycol chitosan NPs (CNPs) have been extensively studied for the past few dec

145 sequencing read depth to successfully obtain CNP genotypes for 1495 CNPs from 487 human DNA samples o

146 t detected at 2h, LH decreases the amount of CNP available to bind to the receptor.

147 Application of CNP potentiated capsaicin- and proton-activated TRPV1 cu

148 The area of CNP increased significantly with higher levels of CVP an

149 best-corrected visual acuity (BCVA), area of CNP, retinal fluorescein transit time (FTT), and an eval

150 ence of rubeosis iridis, and larger areas of CNP that correlate with the degree of CVP elevation.

151 e of a maximally activating concentration of CNP.

152 Specifically, disruption of CNP leads to endothelial dysfunction, hypertension, athe

153 his review, we summarize the distribution of CNP, its evolutionary dynamics within populations, its f

154 addition, strong complementary expression of CNP was detected in the hindbrain at the entry zones of

155 Mechanistically, expression of CNP-hEGFR increased SCP/neurofibroma-initiating cell sel

156 ertension by demonstrating the importance of CNP/NPR-C signaling in preserving vascular homoeostasis.

157 Some cell types express high levels of CNP and we speculate that CNP evolved to restrict lentiv

158 f rat NPR-A due to the promiscuous nature of CNP in this species.

159 Most patterns of CNP in D. melanogaster suggest that negative selection a

160 mpares favourably with the raw percentage of CNP-pixels and also with manual grading.

161 This quantifies the percentage of CNP-pixels in each of 48 sectors and then characterises

162 ificantly enriched >4-fold within regions of CNP.

163 ilator acetylcholine elicited the release of CNP from the coronary endothelium.

164 ances, significant biases remain in terms of CNP discovery and genotyping.

165 , and superoxide dismutase (SOD) activity of CNPs synthesized in various concentration of PEG did not

166 n ARIC and the first genome-wide analysis of CNPs and uric acid.

167 In particular, a recent application of CNPs has shown great potential as an efficient theranost

168 es can increase the range of applications of CNPs.

169 g at higher temperatures, the PL behavior of CNPs strongly depends on the conditions used for their s

170 The current challenges of CNPs to overcome in theranostics are also discussed, and

171 c approach for assessing the contribution of CNPs to heritable traits in large population-based studi

172 discuss the advantages and disadvantages of CNPs-based biosensors that function through various dete

173 deletions, as well as a 4-fold enrichment of CNPs within hotspot regions, compared with control BACs

174 The locations and frequencies of CNPs are strongly shaped by purifying selection, with de

175 e demonstrate that exome-based genotyping of CNPs strongly correlates with whole-genome data (median

176 a model, aimed to investigate the impact of CNPs on marine microgel formation, a critical shunt betw

177 s induced by real-world levels of a panel of CNPs.

178 Several preparations of CNPs with varying Ce(3+):Ce(4+) are produced and are ana

179 Among the various shapes of CNPs, the sea-urchin shape CNPs (SU-CNPs) shows the high

180 plex provides the tunable oxidation state of CNPs.

181 capacity of the active 3+ oxidation state of CNPs.

182 We selected a subset of CNPs for further characterization in 1876 additional sam

183 Synthesis of CNPs in PEG demonstrated a concentration dependent (of P

184 from solonaceae family for the synthesis of CNPs.

185 New methods demonstrate the ubiquity of CNPs in eukaryotes and their medical importance in human

186 tein (GFP) specifically in oligodendrocytes (CNP-GFP mice).

187 w that the DNP tail has a striking effect on CNP, converting it from a non-agonist to a partial agoni

188 is article, the overall research progress on CNPs is reviewed from early works.

189 ure patterns over the Central North Pacific (CNP) imparts a significant signature upon the seasonal-m

190 hift from the oceanic central North Pacific (CNP) to the neritic east Pacific region near the Baja Ca

191 n increase in ambient carbonaceous particle (CNP) levels has been found, potentially leading to signi

192 PEGylated CNPs acted as efficient radical scavengers, and superoxi

193 ability as well as SOD activity of PEGylated CNPs is compared to those of bare CNPs, and the differen

194 ents the fusion of the 22-amino acid peptide CNP together with the 15-amino acid linear C-terminus of

195 C-type natriuretic peptide (CNP) antagonizes FGFR3 downstream signaling by inhibitin

196 tide composed of C-type natriuretic peptide (CNP) fused to the C-terminal tail of Dendroaspis natriur

197 rial arterioles, C-type natriuretic peptide (CNP) has properties consistent with EDHF-like activity.

198 c oxide (NO) and C-type natriuretic peptide (CNP) in the regulation of cartilage development.

199 h Galpha(i), and C-type natriuretic peptide (CNP) treatment induced translocation of protein kinase C

200 c, which encodes C-type natriuretic peptide (CNP), and determined that this mediator is essential for

201 the receptor for C-type natriuretic peptide (CNP), guanylyl cyclase B (GC-B, also known as Npr2 or NP

202 ed of the ligand C-type natriuretic peptide (CNP), its receptor, the guanylyl cyclase natriuretic pep

203 oys an analog of C-type natriuretic peptide (CNP), which antagonizes the mitogen-activated-protein (M

204 e to the agonist C-type natriuretic peptide (CNP).

205 ve properties of C-type natriuretic peptide (CNP).

206 cellular ligand, C-type natriuretic peptide (CNP).

207 c peptide (BNP), type-C natriuretic peptide (CNP)] and their receptors (NPR-A, NPR-B, NPR-C) at sever

208 Capillary non-perfusion (CNP) lesions are central to the pathogenesis of major ca

209 '-3'-cyclic nucleotide 3'-phosphodiesterase (CNP) are associated with the schizophrenic symptom catat

210 ' 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) promoter are shown here to recapitulate features of

211 ',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) promoter-driven overexpression of human EGFR (hEGFR

212 ',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP), a membrane-associated protein with unknown functio

213 ',3'-cyclic nucleotide 3'-phosphodiesterase (CNP)-enhanced green fluorescent protein (EGFP) transgeni

214 ',3'-cyclic nucleotide 3'-phosphodiesterase (CNP)-enhanced green fluorescent protein (EGFP) transgeni

215 ',3'-cyclic nucleotide 3'-phosphodiesterase (CNP)-enhanced green fluorescent protein transgenic mouse

216 ',3'-cyclic nucleotide 3'-phosphodiesterase (CNP)-promoter driven enhanced green fluorescent protein

217 k gap and reach the charge neutrality point (CNP).

218 as well as genotype copy number polymorphic (CNP) loci with high sensitivity and specificity from exo

219 We characterize copy-number polymorphism (CNP) across genomic regions, and we contrast patterns to

220 nd implications of copy number polymorphism (CNP) have only recently become apparent in other organis

221 ied 119 regions of copy-number polymorphism (CNP), 73 of which were previously unreported.

222 several of these copy-number polymorphisms (CNPs) are associated with human diseases, including lupu

223 In addition, copy number polymorphisms (CNPs) are present at higher frequencies in the populatio

224 Whether copy number polymorphisms (CNPs) contribute to uric acid levels is unknown.

225 le genomic map of copy-number polymorphisms (CNPs) in Drosophila melanogaster.

226 ability and LD of copy-number polymorphisms (CNPs) in duplication-rich regions of the genome, we prof

227 Segmental copy-number polymorphisms (CNPs) represent a significant component of human genetic

228 notypes for 1,320 copy number polymorphisms (CNPs) that segregate at an allele frequency >1%.

229 regions of common copy number polymorphisms (CNPs), calls genotypes of SNPs, identifies rare CNVs via

230 including common copy-number polymorphisms (CNPs), in disease.

231 des both SNPs and copy number polymorphisms (CNPs).

232 In CNP-EGFP-positive (CNP-EGFP+) cells, Sox17 mRNA and protein levels transien

233 nt physiochemical and biological properties, CNPs have been investigated for multimodal imaging and t

234 The cognitive neural prosthetic (CNP) is a very versatile method for assisting paralyzed

235 expression of the structural myelin protein CNP is associated with catatonic signs in an age-depende

236 Like other antiretroviral proteins, CNP displays interspecies variation in antiviral activit

237 The copy-number quantitation (CNP phenotype) represents the total number of segmental

238 In streptozotocin-induced diabetic rats, CNP-mediated vascular relaxation in epineurial arteriole

239 of the JCI, Janova et al. show that reduced CNP levels correlate with catatonia and white matter inf

240 oof of concept that BMN 111, a NEP-resistant CNP analog, might benefit individuals with ACH and hypoc

241 tion affected maximum activity at saturating CNP concentrations.

242 various shapes of CNPs, the sea-urchin shape CNPs (SU-CNPs) shows the high product and quantum yield

243 Since CNP may be a regulator of vascular function, a vasopepti

244 NPs) or Bcl-2 siRNA-encapsulated CNPs (siRNA-CNPs) exhibited similar physicochemical properties, incl

245 Schwann cell differentiation markers (SOX10, CNP, PMP22, and NGFR) was down-regulated in MPNSTs where

246 hapes of CNPs, the sea-urchin shape CNPs (SU-CNPs) shows the high product and quantum yield with good

247 In addition, the synthesized SU-CNPs were employed for quantitative detection of a widel

248 first time, we have successfully used the SU-CNPs for live cell detection of ZnO nanoparticles.

249 compatibility study demonstrated that the SU-CNPs were not harmful to the cell up to a very high conc

250 In addition, the SU-CNPs were successfully utilized for the qualitative and

251 the first time that luminescence switchable CNPs can be synthesized for efficient intracellular trac

252 Bare and carboxyl-terminated CNPs did present some toxicity at the cellular level whi

253 l chromogenic rapid test--the Carba NP test (CNP)--and the modified Hodge test (MHT).

254 likely to be population differentiated than CNPs in unique regions (p = 0.015) and that biallelic CN

255 We tested the hypothesis that CNP/NPR-C signaling is a novel regulatory pathway govern

256 ess high levels of CNP and we speculate that CNP evolved to restrict lentivirus replication therein.

257 It was found that CNPs exert marked effects in A549 cells and also contrib

258 We observe that CNPs in segmental duplications are more likely to be pop

259 nd typing the CNPs, and the possibility that CNPs in these regions have rearranged on multiple haplot

260 ase association and our results suggest that CNPs (especially those that cannot be imputed from SNP g

261 The CNP approach relies on scientific understanding of the n

262 The CNP conductance has a two-dimensional character on the o

263 The CNP records the cognitive state of the subject, rather t

264 The CNP-specific receptor (NPR-B) gene was expressed in cell

265 mune responses between the wild-type and the CNP/dnIRF-1 mice were identified throughout the experime

266 Here we use Cre-recombinase driven by the CNP promoter to generate a mouse line with oligodendrocy

267 pt similar receptor-bound conformations, the CNP structure diverges, yet shares sets of common recept

268 e its application through an analysis of the CNP located in gene CCL3L1 in 201 families with asthma.

269 was generated to clarify the pattern of the CNP receptor expression.

270 essure intrusions into the subtropics of the CNP, accompanied by the establishment of persistent, qua

271 The postnatal OB of the CNP-EGFP mouse contained EGFP+ interneurons and oligoden

272 ressure anomalies over high latitudes of the CNP.

273 Only the CNP analog has reached clinical trials.

274 We confirmed that the CNP platform applied to two different types of drugs res

275 The major finding of our study was that the CNP/dnIRF-1 mice, compared with the wild-type mice, were

276 Furthermore, these results suggest that the CNP/NPR-C pathway has potential as a disease-modifying t

277 in which the EGFR is overexpressed under the CNP promoter exhibited enhanced migratory capability.

278 d two different triplet sequences within the CNP ring to their corresponding residues in BNP.

279 an efficient theranostic system because the CNPs could be utilized for a disease-specific theranosti

280 micals could be simply encapsulated into the CNPs through hydrophobic or charge-charge interactions.

281 structure, nitric acid oxidation leaves the CNPs with a surface charge density lower than that of th

282 Some of the CNPs in duplication-rich regions showed strong LD with n

283 y lower than that of the SWNTs, and thus the CNPs do not form stable dispersions in aqueous media dur

284 egions, challenges in mapping and typing the CNPs, and the possibility that CNPs in these regions hav

285 For disease-specific theranostics, CNPs could be simply modified with imaging agents, and t

286 ulated kinases 1 and 2, confirming that this CNP analog inhibits fibroblast-growth-factor-mediated MA

287 in Fgfr3(Y367C/+) mice, treatment with this CNP analog led to a significant recovery of bone growth.

288 d Npr2(+/)(-) fibroblasts was insensitive to CNP treatment, whereas aged Npr2(+/)(-) and Npr2(+/)(-);

289 n converted GC-B-7A from CNP-unresponsive to CNP-responsive.

290 l DNA methylation levels in cells exposed to CNPs at 0.1 mg/L were determined using HPLC-MS and genet

291 cking surface Ce(3+) sites of the most toxic CNP, CNP1, with phosphate treatment reverted toxicity an

292 redox chemistry of the most and least toxic CNPs, CNP1 and CNP2, respectively, were modified by incu

293 ation (e.g., NDE1), myelination (e.g., UGT8, CNP) and oligodendrocyte proliferation (e.g., ENPP2, SEM

294 he cognate receptor that primarily underlies CNP-dependent vasoprotective functions and developed sma

295 hical model in which we infer the underlying CNP phenotype from the (single or replicate) quantitativ

296 the electrochemical response of multi-valent CNPs in presence of hydrogen peroxide and demonstrate an

297 neurofibroma number and size increased when CNP-hEGFR was crossed to Nf1(fl/fl);DhhCre mice.

298 However, it is unknown whether CNP signaling regulates aortic valve health in vivo.

299 rate guanylyl cyclase receptor compared with CNP.

300 umber variation of 70 different genes within CNP intervals, including genes involved in neurological