ライフサイエンスコーパス: CNTF receptor

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1 ents (gp130 and LIFR beta) of the tripartite CNTF receptor.

2 lpha) is the ligand-binding component of the CNTF receptor.

3 lf is not the only endogenous ligand for the CNTF receptor.

4 lly characterize cells containing functional CNTF receptors.

5 Unconditional disruption of the mouse CNTF receptor alpha (CNTFRalpha) gene leads to MN loss,

6 nd adult-onset conditional disruption of the CNTF receptor alpha (CNTFRalpha) gene to directly examin

7 ohistochemistry to analyze the expression of CNTF receptor alpha (CNTFRalpha) in mouse retina and opt

8 signaling in SVZ NSP cells, with a "floxed" CNTF receptor alpha (CNTFRalpha) mouse line and a gene c

9 ns and leads to behavioural recovery through CNTF receptor alpha (CNTFRalpha) on nigral dopamine neur

10 Expression of CNTF receptor alpha (CNTFRalpha), an essential CNTF rece

11 CNTF and CNTF receptor alpha subunit (CNTFRalpha) in CE cells and

12 ibody targeted to the gp130 component of the CNTF receptor) and AG490 (an inhibitor of the JAK/STAT p

13 We hypothesized that CNTF receptors are present on cardiomyocytes and their a

14 While indicating that CNTF receptors can promote adult MN survival, the data d

15 als, the ligand-binding alpha-subunit of the CNTF receptor (CNTFRalpha) is expressed in a variety of

16 w that the CNTF-binding alpha-subunit of the CNTF receptor (CNTFRalpha) is released from injured tiss

17 ther CNTF itself or the alpha-subunit of the CNTF receptor (CNTFRalpha) to assess whether CNTF and/or

18 The localization of CNTF receptors (CNTFRalpha) to the sarcolemma in C57BL/6

19 rate that the expression of two of the three CNTF receptor complex components, CNTFRalpha and LIFR, d

20 rt the idea that a ligand for the tripartite CNTF receptor complex plays a role in ENS development.

21 on fat cells, we examined the expression of CNTF receptor complex proteins (LIFR, gp130, and CNTFRal

22 omponent of the ciliary neurotrophic factor (CNTF) receptor complex upon stimulation with CNTF.

23 CNTF-receptor complex members, CNTFRalpha, LIFRbeta and

24 TF receptor alpha (CNTFRalpha), an essential CNTF receptor component, is greatly increased in skeleta

25 better understanding of the roles played by CNTF receptors in adult MNs.

26 amine the in vivo roles played by endogenous CNTF receptors in adult motor neuron survival and ChAT m

27 ervations suggest that signaling through the CNTF receptor is involved in sexually dimorphic developm

28 These data also suggest that CNTF receptors may promote adult MN survival and that ap

29 CNTF and CNTF receptor mRNA levels were highest at embryonic day

30 The developmental increase in atrial CNTF receptor mRNA was enhanced by stimulating muscarini

31 Levels of atrial CNTF receptor mRNA were fourfold greater at E13 than at

32 These results suggest that the CNTF receptor performs distinct developmental functions

33 at, although neither motor neuron nor muscle CNTF receptors play a significant, nonredundant role in

34 d motor neurons, indicating that these adult CNTF receptors play no essential survival role in this m

35 The data also indicate that in vivo CNTF receptors play very different roles in adult and em

36 Activation of the CNTF receptor promoted differentiation of cerebral corti

37 mouse retinal explants lacking a functional CNTF receptor, relative to wild-type littermates.

38 ion with our previous study, that endogenous CNTF receptor signaling can protect MNs against toxic in

39 Disruption of in vivo CNTF receptor signaling in SVZ NSP cells, with a "floxed

40 Together, the data suggest that endogenous CNTF receptor signaling in type B stem cells inhibits ad

41 strating a developmental role for endogenous CNTF receptor signaling.

42 that endogenous ciliary neurotrophic factor (CNTF) receptor signaling may inhibit neuronal differenti

43 sted that functional differences in the CNTF/CNTF receptor system between chicks and mammals exist.

44 tural features with CNTF and signals via the CNTF receptor tripartite complex comprised of CNTFRalpha

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