ライフサイエンスコーパス: CR

1 CR also worsened with increasing choroidal thickness, bu

2 CR cells can be used for various applications, including

3 CR expands the period of maximal SNF1 activation beyond

4 CR may relate to executive functioning and semantic know

5 CR was similar across various causes of retinal fluid, b

6 CR was tolerated well.

7 CR-Kp are isolated from patients with ever greater frequ

8 CRs against hookworm infection were 57% (moxidectin) and

9 relapsed/refractory CLL, 56% (n = 55) with 1 CR; peripheral TCL, 50% (n = 16) with 3 CR; and cutaneou

10 ) and role-functioning scores (86.3 vs 74.1, CR medium, P < 0.001).

11 ed 21-51 y who were randomly assigned to 25% CR (CR, n = 143) or ad libitum control (AL, n = 75) in a

12 ndex (in kg/m(2)): 22-28] men and women (25% CR: n = 24; control: n = 15) 12 and 24 mo after they com

13 (50%) responded to bendamustine-rituximab (3 CR and 4 PR).

14 th 1 CR; peripheral TCL, 50% (n = 16) with 3 CR; and cutaneous TCL, 32% (n = 19).

15 Of the 38 CR patients, 16 received a consolidative stem cell trans

16 +/- SDs.The CR group achieved 11.9% +/- 0.7% CR over 2-y and had significant decreases in weight (-7.

17 emonstrated higher global QOL (78.7 vs 69.7, CR small, P < 0.001), physical (86.7 vs 77.9, CR small,

18 ing criteria 4 weeks after infusion was 74% (CR, 4/19, 21%; PR, 10/19, 53%), and 15/17 patients (88%)

19 R small, P < 0.001), physical (86.7 vs 77.9, CR small, P < 0.001) and role-functioning scores (86.3 v

20 Of 2 patients with ALCL, 1 had a CR that persisted 9 months after the fourth infusion of

21 Here, a CR-C knockout mouse was established to determine its rol

22 We observed a CR of 93.7% (59/63) for moxidectin compared to 95.2% (59

23 maintenance for 24 months after obtaining a CR or PR to R-CHOP significantly prolonged PFS in elderl

24 et (CD), a 16 week high-fat diet (HFD), or a CR diet to compare and contrast the effects of these die

25 Mice were randomized to receive a CR, overweight-inducing, or diet-induced obesity regimen

26 f 655 treated patients, 105 (16.0%) achieved CR after median follow-up of 43 months.

27 ients, 16 (36%; 95% CI, 22% to 51%) achieved CR/CRh during the first two cycles, including four of 10

28 An additional 7 patients achieved CR by day 56.

29 ay be more effective than cTACE in achieving CR.

30 inuria </=0.3, 0.4-3.4, and >/=3.5 g/d after CR or PR, respectively.

31 on after pembrolizumab discontinuation after CR.

32 atients who discontinued pembrolizumab after CR for observation.

33 Although CR-PIT can induce tumor killing deep within body, it is

34 For this analysis, CR was defined per investigator assessment, immune-relat

35 nding locations for these factors in HFD and CR livers.

36 ge prevalence was uncommon (2-3%) in IHO and CR adults.

37 consistent developmental modular marker, and CR label separate, nonoverlapping LCIC compartments.

38 n-dependent axonal/synaptic organization and CR expression when transplanted heterotopically.

39 This study validates and quantifies PR and CR as surrogates for long-term outcome in MGN.

40 Separate analyses for PR and CR yielded similar results.

41 ologous expression systems, both the TMD and CR of PCDH15 have been shown to interact with members of

42 prevalence was similar among IHO workers and CR adults (12% vs. 8%; aPR: 1.14; 95% CI: 0.56, 2.29).

43 AAC eyes into four subgroups: crowded-angle (CR), lens subluxation (LS) pupillary block (PB), and pla

44 th sex differences, urge caution in applying CR to improve skeletal muscle function across the lifesp

45 ggests that lifelong bilingualism may act as CR delaying the onset of dementia by approximately 4.5 y

46 .001) and in studies specifically looking at CR patients (HR, 0.44; 95% CI, 0.34-0.56; P < .001).

47 However, because CR+ interneurons are relatively scarce in rodent striatu

48 Differences between CRs were estimated as -1.5% percentage points (95% CI, -

49 We found that both CR and HFD induce extensive transcriptional changes, in

50 he phosphatidylinositol-4 kinase Stt4, build CRs that can slide away from the cell middle during anap

51 The fact that changes induced by CR do not persist with time and the dissimilarities betw

52 derived from skeletal muscle was reduced by CR at various stages.

53 ls derived from these muscles was reduced by CR.

54 Igf-1 expression is regulated by CR and by the circadian clock, we found that rhythms in

55 genes previously reported to be regulated by CR: Fmo3, Mup4, Serpina12 and Cyp4a12, while the express

56 Conserved region C (CR-C), a promoter proximal cis-regulatory element that i

57 D), cytochrome oxidase (CO), and calretinin (CR).

58 y, a subclass of h-ChCs exhibits calretinin (CR) expression, which is not found in nc-ChCs.

59 kers including parvalbumin (PV), calretinin (CR), SMI-32, and GAD65/67 .

60 trolled-release carbamazepine (carbamazepine-CR) twice daily.

61 g/day lacosamide or 200 mg/day carbamazepine-CR, uptitration to the first target level of 200 mg/day

62 ide and 800 or 1200 mg/day for carbamazepine-CR) over 2 weeks with a 1-week stabilisation period, and

63 samide and 332 (75%) receiving carbamazepine-CR.

64 king lacosamide and 91% taking carbamazepine-CR (absolute treatment-difference: -1.3%, 95% CI -5.5 to

65 lacosamide and 43 (10%) taking carbamazepine-CR had serious treatment-emergent adverse events, and 47

66 king lacosamide and 442 taking carbamazepine-CR were included in the full analysis set (took at least

67 ide group and 308 (70%) in the carbamazepine-CR group completed 6 months of treatment without seizure

68 ty criteria when compared with carbamazepine-CR.

69 f actin and myosin II within the animal cell CR remains an unanswered question.

70 /47% with R-ACVBP and 41%/39% with R-CHOP14 (CR 95% confidence interval [CI], 38%-67% and 28%-54%, re

71 ant lymphopenia (Brincidofovir vs cidofovir; CR = 13 (80%) vs 8 (35%); median lymphocyte count = 320/

72 and at least two treatments beyond confirmed CR could discontinue therapy.

73 In contrast, CR patterns appear complementary, preferentially stainin

74 1-51 y who were randomly assigned to 25% CR (CR, n = 143) or ad libitum control (AL, n = 75) in a 2:1

75 Patients with complete response (CR)/CR with incomplete count recovery had higher levels of C

76 CRIPTO (CR-1, TDGF1) is a cell surface/secreted oncoprotein acti

77 Cys (CP) and, if present, the resolving Cys (CR).

78 ngs demonstrate that the TMD and cytoplasmic CR domains are required for the in vivo function of Pcdh

79 aRT was associated with decreased CR rate in patients with two or more risk factors (10-ye

80 The Efr3-dependent CR-anchoring mechanism is distinct from previously repor

81 lated to evaluate performance in determining CR from pre- and post-CRT ADCs and ADC change.

82 n also identified a topographically distinct CR+ interneuron population with a rostral bias similar t

83 The mechanisms underlying durable CR require further investigation.

84 intake, predicted preservation of FFM during CR (P < 0.01).

85 g-term follow-up in patients who experienced CR with pembrolizumab in the KEYNOTE-001 study.

86 Calretinin-expressing (CR+) interneurons are the most common type of striatal i

87 These extraordinary CRs in fungi generate substantial genome plasticity comp

88 ith median follow-up of 30 months from first CR.

89 e of clinically relevant pancreatic fistula (CR-POPF) compared with OPD.

90 s of clinically relevant pancreatic fistula (CR-POPF)-the most common and morbid complication after P

91 PD - clinically relevant pancreatic fistula (CR-POPF).

92 Following CR and superior IC lesions, the dispersed pathway distri

93 ormity in the track diameter is observed for CR-39 with thickness matching with the stopping range of

94 g RPD was associated with a reduced risk for CR-POPF incidence (OR, 0.4 [95% CI, 0.2-0.7]; P = .002)

95 These data implicate a critical role for CR-C in governing PD-1 expression, and a subsequent role

96 Of the four CR-KP isolates, two had no evidence of enhanced pathogen

97 transcription factors are required for full CR-induced CLS extension, implicating an alternative car

98 At data cutoff, 92 patients (87.6%) had CR, with median follow-up of 30 months from first CR.

99 B-cell lymphoma were 60 to 80 years old, had CR or PR after six or eight cycles of R-CHOP, and were r

100 ines of therapy, with a previous hematologic CR in only 5 patients.

101 High CR was associated with semantic tasks in patients with b

102 High CR was significantly associated with performance on the

103 High CR was significantly associated with performance on the

104 Intergrader ICC (CR) was 0.95 (74.1 mum) and 0.96 (63.9 mum) for subfovea

105 R, 0.57; 95% CI, 0.46-0.71; P < .001) and in CR patients (HR, 0.47; 95% CI, 0.33-0.67; P < .001).

106 vents included two relapses and one death in CR in the ATRA-ATO arm and two instances of molecular re

107 nsolidation, 15 relapses, and five deaths in CR in the ATRA-CHT arm.

108 ated alleles of recurrently mutated genes in CR marrows of AML patients at levels as low as 0.002% va

109 Most gene mutations persisted in CR, albeit at highly variable and gene-dependent levels.

110 , antiandrogens modify androgen signaling in CR-VCaP xenografts at multiple levels.

111 The lens position in PL was greater than in CR and LS (p < 0.05 and <0.01, respectively).

112 uniquely characterize the particle tracks in CR-39, enabling comparative description of the track cha

113 nfidence interval (CI) of the differences in CRs not exceed 7 percentage points.

114 ction, given that only slight differences in CRs were observed.

115 ponse rate to daratumumab was 76%, including CR in 36% and very good partial response in 24%.

116 Indeed, CR increased acetyl-CoA levels during the diauxic shift,

117 es of progression occurring after an initial CR, of which 10 (24%) were classified as target progress

118 dance of certain foods.After a 2-y intensive CR intervention, approximately 50% of CR-induced weight

119 Risk for ISGPF CR-POPF was determined intraoperatively using the Fistul

120 oaches such as KNN based on correlation (KNN-CR) and KNN based on Euclidean distance (KNN-EU).

121 es of the different datasets compared to KNN-CR and KNN-EU when there is missingness due to missing a

122 he Southwest (n = 95 Upper CR, n = 130 Lower CR) were highest in lowland mainstem rivers impacted by

123 O) phagocytes, and this was rescued in Mertk(CR) mice.

124 More notably, Mertk(CR) mice, which are resistant to cleavage, showed signif

125 novel multivariate curve resolution method (CR), principal component analysis (PCA) and linear discr

126 month) and longer term (8.5 and 18.5 months) CR on skeletal muscle in male and female C57Bl/6 and DBA

127 Moreover, CR+ interneurons are often treated in models as a single

128 and overall survival (OS) compared with near-CR or partial response (median PFS, 27, 27, and 29 month

129 the arginine glycosyltransferase NleB1 (NleB(CR) in C. rodentium) that modifies conserved arginine re

130 with type 2 diabetes with abdominal obesity, CR ameliorates glomerular hyperfiltration, insulin sensi

131 We observed CRs ranging from 92.7% to 95.5% and ERRs >99.5% for all

132 ensive CR intervention, approximately 50% of CR-induced weight loss was maintained 2 y later, which w

133 10 patients with the T315I mutation; 88% of CR/CRh responders achieved a complete minimal residual d

134 primates, in which the relative abundance of CR+ interneurons suggests that they play a critical role

135 r these data confirm that health benefits of CR are conserved in monkeys and suggest that CR mechanis

136 Deletion of CR-C decreased PD-1 expression on CD4 T cells and Ag-spe

137 iameter, the energy resolution (deltaE/E) of CR-39 for few MeV protons and Carbon ion is found to be

138 es were initiated to determine the effect of CR in rhesus monkeys.

139 iods (Per1, Per2 and Per3) and the effect of CR on the expression of these genes were sex independent

140 models were used to determine the effects of CR (years of education) on cognitive performance after c

141 Many physiological effects of CR differ between males and females; here we investigate

142 e the metabolic and psychological effects of CR in nonobese humans.We conducted a 2-y follow-up study

143 The expression and the effects of CR were sex-specific for several genes previously report

144 lls, we evaluated the therapeutic effects of CR-PIT in vitro and in vivo using bioluminescence imagin

145 report species specificity in the impact of CR in terms of optimal onset and diet.

146 ment with our predictions and with models of CR, cerebral hypometabolism was more severe in the group

147 The power of CR-FS and SVM classification is further demonstrated by

148 r score > 0.6 were independent predictors of CR (all P < .01).

149 Data are limited on potential predictors of CR and patient disposition after pembrolizumab discontin

150 sponse criteria, and potential predictors of CR were evaluated using univariate and multivariate anal

151 The response of CR-39 to ions is studied based on the energy dependent g

152 ecessary adverse effects, and reduce risk of CR in the subset of patients (approximately 25% of all p

153 as used to establish the surface staining of CR-Kp strains.

154 In a subset of CR patients, mIDH2 allele burden was reduced and remaine

155 formation on the front and rear surfaces of CR-39 produced by laser-driven protons and carbon ions.

156 onth disease-free survival rate from time of CR was 90.9% in all 105 patients with CR and 89.9% in th

157 ive status surpasses the prognostic value of CR achievement for PFS and OS across the disease spectru

158 llow-up study of adults who underwent 2 y of CR or ad libitum (control) consumption and determined wh

159 001) than women in the CR group.Two years of CR had broadly favorable effects on both whole-body and

160 ary end point was complete remission (CR) or CR with partial hematologic recovery (CRh) during the fi

161 as similar in patients with lymph node PR or CR by IWCLL criteria.

162 ed with either undergoing robotic surgery or CR-POPF occurrence on logistic regression analysis.

163 Overall CR-POPF rates were significantly lower after protocol im

164 After matching, the overall CR rate (P = .94), TTP (P = .83), and overall survival (

165 synthase, OsCesA8, plant-conserved region (P-CR), one of two unique domains in the catalytic domain o

166 om the molecular docking models places the P-CR connector loop into a hydrophobic pocket of the catal

167 was fit into a molecular envelope for the P-CR domain derived from small-angle X-ray scattering data

168 The predicted position for the P-CR domain from the molecular docking models places the P

169 The P-CR structure and molecular envelope, combined with a hom

170 The P-CR structure was fit into a molecular envelope for the P

171 PET4(-)/CR rates were 53%/47% with R-ACVBP and 41%/39% with R-CH

172 carpabenem-resistant Klebsiella pneumoniae (CR-Kp) are especially problematic, with a 50 % average s

173 hat lifelong bilingualism acts as a powerful CR proxy in dementia and exerts neuroprotective effects

174 Application of the proposed CR method to VOO samples provided the two pure-component

175 4) motor regions through the corona radiata (CR), internal capsule (IC) and crus cerebri of the cereb

176 nse rate of 24% and a clinical benefit rate (CR/PR/SD > 6 months) of 44%, higher than previously repo

177 Cure rate (CR) against S. stercoralis was the primary outcome.

178 y resulting from chromosomal rearrangements (CRs) are widely documented in fungal genomes.

179 ing Decipher score) and clinical recurrence (CR), which were then used to develop a novel risk-strati

180 household pairs and 202 community referent (CR) adult-child household pairs completed a questionnair

181 verweight and diet-induced obesity regimens, CR decreased body weight, adiposity, and serum metabolic

182 a that contains the so-called common region (CR) at the cytoplasmic/membrane interface still has the

183 acellular domain known as the common region (CR).

184 The Cancer Register (CR) in Sweden has reported that the incidence of primary

185 Clinical relevance (CR) of differences was scored as small (5-10), moderate

186 molecular or hematologic complete remission (CR) after T-cell therapy, upon emergence of (p190)BCR-AB

187 are the RR group and the complete remission (CR) group (a total of 42 adult AML patients).

188 Results Achievement of complete remission (CR) in the absence of MRD negativity was not associated

189 of 136 patients achieved complete remission (CR) in the ATRA-ATO and ATRA-CHT arms, respectively ( P

190 he primary end point was complete remission (CR) or CR with partial hematologic recovery (CRh) during

191 Complete remission (CR) with persistence of mIDH2 and normalization of hemat

192 requently relapses after complete remission (CR), necessitating improved detection and phenotypic cha

193 We defined complete remission (CR), partial remission (PR), and relapse as proteinuria

194 rotocol describes conditional reprogramming (CR), which involves coculture of irradiated mouse fibrob

195 or cell cultures, conditional reprogramming (CR), with a rapid, reproducible and robust in-vivo zebra

196 Cognitive reserve (CR) is one factor that helps to maintain cognitive funct

197 Cognitive reserve (CR) prevents cognitive decline and delays neurodegenerat

198 ent (hvKP) strains and carbapenem-resistant (CR-KP) strains.

199 sponders (NR = 13), and complete responders (CR = 14) to CRT, as defined by a tumor regression score,

200 concentration on the colorimetric response (CR) were examined.

201 ponded; 18 (40%) achieved complete response (CR) and 14 (31%) partial response (PR).

202 21 evaluable patients was complete response (CR) in 2 (9.5%) and stable disease in 7 (33.3%), yieldin

203 tatic melanoma, including complete response (CR) in about 15% of patients.

204 with DLBCL who achieved a complete response (CR) or partial response (PR) to R-CHOP induction.

205 ternational working group complete response (CR) rate after induction.

206 The overall complete response (CR) rate was 82.9% for RS and 82.5% for TACE MWA (odds r

207 The complete response (CR) rates by patient or by tumor were both 100%.

208 ents on the assessment of complete response (CR) to neoadjuvant combined chemotherapy and radiation t

209 is (AL) fail to achieve a complete response (CR) to standard light chain suppressive chemotherapy, an

210 Patients with a complete response (CR), as assessed by the investigator (38 of 58, 66%), co

211 Patients with complete response (CR)/CR with incomplete count recovery had higher levels

212 he overall response rate (complete response [CR] and/or partial response [PR]) by International Works

213 patients and resulted in complete responses (CR) despite significant lymphopenia (Brincidofovir vs ci

214 ed significantly less conditioned responses (CR) compared to controls with slower learning rates.

215 ate, 58% (n = 31) with 6 complete responses (CRs); relapsed/refractory CLL, 56% (n = 55) with 1 CR; p

216 cks to 6 months of a 25% calorie restricted (CR) or standard diet (SD).

217 etabolic diseases, while calorie-restricted (CR) diets can improve health and extend lifespan.

218 Importantly, caloric restriction (CR) extends lifespan in several organisms and rewires ci

219 Caloric restriction (CR) without malnutrition extends lifespan and delays the

220 ical life span (CLS) by caloric restriction (CR).

221 Calorie restriction (CR) increases the lifespan of C57Bl/6 mice, but not in t

222 Calorie restriction (CR) influences aging processes and extends average and m

223 ght maintenance through calorie restriction (CR) may limit risk of HER2-positive breast cancer.

224 success, weight loss by calorie restriction (CR) often fails because of rebound weight gain.

225 Calorie restriction (CR) retards aging and increases longevity in many animal

226 k genes are affected by calorie restriction (CR), a dietary paradigm known to increase lifespan.

227 ng animals living under calorie restriction (CR).

228 an actin- and myosin-based contractile ring (CR) that is physically linked to the plasma membrane (PM

229 spatial regulation of the contractile ring (CR), the precise ultrastructure of actin and myosin II w

230 ishes in the Upper and Lower Colorado River (CR), Alabama-Coosa-Tallapoosa (ACT), and Apalachicola-Ch

231 using cluster resolution feature selection (CR-FS) and support vector machine (SVM) classification.

232 rdize older non-spatial CR and newer spatial CR density estimates and examine trends for critically e

233 an approach to standardize older non-spatial CR and newer spatial CR density estimates and examine tr

234 homeobox protein 7 (Lhx7) separates striatal CR+ interneurons into three structurally and topographic

235 ogether, these results suggest that striatal CR+ interneurons comprise at least three molecularly, st

236 In the survival study, CR elicited a significant suppression in spontaneous mam

237 ho were in the follow-up study, 29 subjects (CR: n = 18; control: n = 11) completed all visits at fol

238 circulating acyl-ghrelin levels, suppressed CR-provoked ghrelin signaling, and restored central ghre

239 We found that short-term CR increased the satellite cell number and collagen VI c

240 thetase genes ACS1 and ACS2 We conclude that CR maximizes Snf1 activity throughout and beyond the dia

241 CR are conserved in monkeys and suggest that CR mechanisms are likely translatable to human health.

242 Recent reports, however, suggest that CR-KP strains are increasing in virulence.

243 The CR may underestimate the liver cancer incidence by 37%-4

244 The CR+/Scgn-/SP8-/Lhx7+ interneurons are relatively large-s

245 The CR, the Cause of Death Register, and the Patient Registe

246 The CR-FS algorithm improves class discrimination and indica

247 vestigated if the sex of animals affects the CR induced changes in the circadian rhythms.

248 plus bendamustine, the ORR was 100% and the CR rate was 88%.

249 as considerably higher than estimated by the CR, with a stable incidence over time; reporting needs t

250 When either the CR or TMD domain was deleted, the mutated proteins local

251 Finally, the CR/zebrafish model mirrors the PDX mouse model and ident

252 embrane-binding proteins were reduced in the CR and/or on the PM.

253 In the CR each pathway was segregated.

254 h the reduced body mass; although men in the CR group lost more FFM than the women did, the percentag

255 Men in the CR group lost significantly more trunk fat (P = 0.03) an

256 igher, and percentage of FM was lower in the CR group than in the AL.

257 did, the percentage of FFM in the men in the CR group was higher than at baseline.

258 of weight loss (P < 0.001) than women in the CR group.Two years of CR had broadly favorable effects o

259 nd dihydrotestosterone concentrations in the CR-VCaP tumors, indicating that the reduction in intratu

260 d cancer reports or misclassification in the CR.

261 ant to stabilize the central position of the CR and resist myosin V-based forces to promote the fidel

262 n AAV-NT mice, the signaling pathways of the CR mediators, AMP-activated protein kinase (AMPK) and si

263 Values are expressed as means +/- SDs.The CR group achieved 11.9% +/- 0.7% CR over 2-y and had sig

264 ring constriction, but also suggest that the CR may be derived from foci of myosin II filaments in a

265 These results demonstrate that the CR plays a key role in the mechanotransduction complex i

266 and assess the underreporting of PLC to the CR and to produce a more accurate estimate based on thre

267 ts show that 98% of the PLCs reported to the CR were histologically verified; 80% were hepatocellular

268 diagnostic method, should be reported to the CR, the PLC incidence may not reflect the true rate.

269 At follow-up, the CR group retained higher degrees of dietary restraint an

270 TEM showed that actin within the CR formed a dense and anisotropic array of elongate, ant

271 ination microscopy indicated that within the CR, actin and myosin II filaments were organized into ti

272 Cox models that included MRD (as opposed to CR) for response assessment.

273 hms in gene expression and their response to CR.

274 % could yield translucency values ( TIT, TP, CR) similar to those of the commercial high-translucency

275 s that a similar, C-terminally retracted (Ub-CR) conformation also exists at low population in wild-t

276 biquitin in the 'C-terminally retracted' (Ub-CR) conformation.

277 lises a lowly populated yet more suitable Ub-CR conformation of Ub for efficient phosphorylation.

278 The flexible Ser65 loop in the Ub-CR conformation contacts the activation segment, facilit

279 he two states, and we show that while the Ub-CR conformation is defective for conjugation, it demonst

280 nd neighbouring beta-strands shift the Ub/Ub-CR equilibrium.

281 Moreover, de novo oscillating genes under CR show an enrichment in SIRT1 targets in the liver.

282 extirpations in the Southwest (n = 95 Upper CR, n = 130 Lower CR) were highest in lowland mainstem r

283 ere, we demonstrate the feasibility of using CR generated by (18)F-FDG accumulated in tumors to induc

284 nger than 70 v >/= 70 years), response (PR v CR) after R-CHOP, and positron emission tomography statu

285 hotopically grown castration-resistant VCaP (CR-VCaP) xenografts express high levels of AR and retain

286 gnostic superiority of MRD negativity versus CR particularly evident in patients with high-risk cytog

287 The major outcome of interest was CR-POPF occurrence, which is the most common and morbid

288 However, it is unclear whether CR can be implemented in humans without adverse effects

289 n in acetylation is absent in old mice while CR robustly rescues global protein acetylation.

290 seline factors independently associated with CR by univariate analysis.

291 nce was higher among IHO (53%) compared with CR (31%) adults [adjusted prevalence ratio (aPR): 1.40;

292 ime of CR was 90.9% in all 105 patients with CR and 89.9% in the 67 patients who discontinued pembrol

293 response durations of the two patients with CR were 7.5 and 8.8 months.

294 indicate that combining BChE treatment with CR could be an effective approach in treating human obes

295 composition.We evaluated the effect of a 2-y CR regimen on body composition including the influence o

296 ients with two or more risk factors (10-year CR rate 10.1% in aRT v 42.1% in initial observation; P =

297 The 10-year CR rate was 4.9% vs. 17.4% in patients treated with aRT

298 deposits were significantly increased in ZDF-CR and ZDF-ND rats as compared to ZL controls, while UCP

299 er calorie restriction in diabetic rats (ZDF-CR).

300 (ZDF-ND) and a mild calorie restriction (ZDF-CR) group.