ライフサイエンスコーパス: CRPS

1 CRPS symptoms likely reflect combined effects of axonal

2 ent (phenylephrine) in 4 patients with acute CRPS I and 3 patients with resolved CRPS I with that in

3 in the affected limb of patients with acute CRPS I compared to their unaffected limb (p = 0.03), to

4 the abnormal response in patients with acute CRPS I is most likely mediated by an axon reflex and tha

5 ctivation similar to those reported in adult CRPS; (ii) in the CRPS(+) state, stimuli that evoked mec

6 respiratory sinus arrhythmia, do not affect CRPS.

7 Compared with controls, CBP and CRPS, but not OA, had significantly less bilateral hippo

8 were perceived as equivalent in CRPS(+) and CRPS(-) states, the same stimulus produced different pat

9 within-group analysis for CRPS(+) state and CRPS(-) state for brush and cold for the affected and un

10 all-fiber-predominant polyneuropathies cause CRPS-like abnormalities, and pathological studies of ner

11 pathological studies of nerves from chronic CRPS-I patients confirm small-fiber-predominant patholog

12 roke and raises the possibility that chronic CRPS involves a type of spatial neglect.

13 Compared to controls, CRPS patients particularly showed a significant prolonga

14 n the clinical findings required to diagnose CRPS.

15 ng finger tapping of the affected extremity, CRPS patients showed a significant reorganization of cen

16 For CRPS patients, pain (measured on a 100-mm visual analog

17 ere performed: (i) within-group analysis for CRPS(+) state and CRPS(-) state for brush and cold for t

18 h fields suggest novel treatment options for CRPS: from targeting autoimmunity to correcting abnormal

19 the NOS substrate l-arginine in plasma from CRPS patients, suggesting reduced miR-939 levels may con

20 -edematous agents in patients suffering from CRPS, and interestingly these therapeutic effects appear

21 esults do not apply to patients who have had CRPS for less than 1 year or more than 5 years and do no

22 ng a 6-week period in adult patients who had CRPS from 1 to 5 years.

23 However, CRPS is associated with symptoms that appear similar to

24 with complex regional pain syndrome type I (CRPS I).

25 ; now complex regional pain syndrome type I [CRPS-I]).

26 the complex regional pain syndrome type II (CRPS II or causalgia) in man.

27 genes and that downregulation of miR-939 in CRPS patients may increase expression of these genes, re

28 r morphometry and white matter anisotropy in CRPS patients and matched controls.

29 Our results show that the difference in CRPS between sleep stages exceeds the difference between

30 sought to characterize motor dysfunction in CRPS patients using kinematic analysis and functional im

31 ffected limb were perceived as equivalent in CRPS(+) and CRPS(-) states, the same stimulus produced d

32 ivations in affected and unaffected limbs in CRPS or post-CRPS states.

33 obe may explain some CNS-related symptoms in CRPS, including movement disorders and hemineglect/inatt

34 s system may contribute to motor symptoms in CRPS.

35 Abnormalities in the immune system in CRPS have also been demonstrated.

36 p-stage stratification pattern we uncover in CRPS does not break down with advanced age, and surprisi

37 t sympatho-vagal balance strongly influences CRPS.

38 tal nerve injuries in rodents reproduce many CRPS features, further supporting this hypothesis.

39 Most CRPS features-spreading pain and skin hypersensitivity,

40 For non-CRPS patients, pain increased by 1.4 +/- 4.1 mm and swel

41 ome (CRPS) were compared with those with non-CRPS pain.

42 We find that the degree of CRPS in healthy subjects dramatically changes with sleep

43 subjects, we find that the overall degree of CRPS is reduced by approximately 40%, which has importan

44 ings on diagnostic imaging, the diagnosis of CRPS was made.

45 of favorable outcomes following diagnosis of CRPS.

46 the affected limb is an important feature of CRPS I, we investigated whether this supersensitivity al

47 avasation observed in the edematous hands of CRPS patients.

48 Multiple mechanisms of CRPS have been suggested, and recent research has begun

49 of the choroid plexus in the pathogenesis of CRPS.

50 tical role in the global clinical picture of CRPS.

51 anisms underlying pain and other symptoms of CRPS.

52 Many of the advances in our understanding of CRPS have arisen from the development of collaborative r

53 sions: once during an active period of pain (CRPS(+)), and once after symptomatic recovery (CRPS(-)).

54 ffected and unaffected limbs in CRPS or post-CRPS states.

55 r dermatologists to understand and recognize CRPS as a neurological disorder with major dermatologic

56 PS(+)), and once after symptomatic recovery (CRPS(-)).

57 r unaffected limbs of patients with resolved CRPS I (p = 0.02), whose sweat response was not signific

58 th acute CRPS I and 3 patients with resolved CRPS I with that in 9 control subjects using the methodo

59 estoring the interest of neurologists in RSD/CRPS should improve patient care and broaden our knowled

60 We propose that persistent RSD/CRPS-I is a post-traumatic neuralgia associated with dis

61 ing the continuous ranked probability score (CRPS).

62 111 patients with moderate or severe CRPS of 1 to 5 years' duration.

63 ing pain in patients with moderate to severe CRPS of 1 to 5 years' duration.

64 how cardiorespiratory phase synchronization (CRPS) responds to changes in physiological states and co

65 ffering from complex regional pain syndrome (CRPS) compared with age- and gender-matched healthy subj

66 se course of complex regional pain syndrome (CRPS) has been unclear until recently.

67 Complex regional pain syndrome (CRPS) in paediatric patients is clinically distinct from

68 Complex regional pain syndrome (CRPS) is a chronic pain condition usually affecting the

69 Chronic complex regional pain syndrome (CRPS) is a debilitating pain condition accompanied by au

70 The complex regional pain syndrome (CRPS) is a disabling neuropathic pain condition that may

71 Complex regional pain syndrome (CRPS) occurs after stroke, but most cases develop after

72 atients with complex regional pain syndrome (CRPS) were compared with those with non-CRPS pain.

73 symptoms of complex regional pain syndrome (CRPS), a rare posttraumatic pain condition.

74 pain (CBP), complex regional pain syndrome (CRPS), and osteoarthritis patients (OA).

75 atients with complex regional pain syndrome (CRPS).

76 criteria for Complex Regional Pain Syndrome (CRPS).

77 Since a critical rate of protein synthesis (CRPS) is known to mediate passage through Start and dete

78 We demonstrate that CRPS and the traditionally studied respiratory sinus arr

79 These results show that CRPS is associated with a deficit in tactile processing

80 limb edema in both the animal model and the CRPS patient, and that the anti-edematous effects of MP

81 We found: (i) in the CRPS(+) state, stimuli that evoked mechanical or cold al

82 to those reported in adult CRPS; (ii) in the CRPS(+) state, stimuli that evoked mechanical or cold al

83 ers and hemineglect/inattention; (iv) in the CRPS(-) state, significant activation differences persis

84 activations during tapping movements of the CRPS-affected hand in 12 patients compared to healthy co

85 Similar to the CRPS clinical response to glucocorticoids, we now demons

86 ad sensory abnormalities, not limited to the CRPS limb, have been found suggesting that systemic chan

87 tion in the two states, suggesting that the 'CRPS brain' responds differently to normal stimuli appli

88 spontaneous neurogenic extravasation in this CRPS model contributed to the development and maintenanc

89 nic hindpaw edema in the sciatic transection CRPS model is reversed by a continuous infusion of MP (3

90 This supersensitivity is reversed when CRPS I resolves.

91 Ten participants (four males) with CRPS of one arm performed temporal order judgements of p

92 after a peripheral injury and overlaps with CRPS.

93 National registries of patients with CRPS have provided us with an invaluable insight into th

94 nt changes in CNS circuitry in patients with CRPS.

95 ion in paediatric patients (9-18 years) with CRPS affecting the lower extremity.