ライフサイエンスコーパス: CTP

1 CTP class B (HR 16.5; 95% CI 3.4-68.2; P < 0.0001) and p

2 CTP images were analyzed quantitatively for the presence

3 CTP not only allows early detection of cerebral ischemia

4 CTP originates from two sources: a salvage pathway and a

5 CTP synthase activity is a potentially important step fo

6 CTP synthase filaments are evolutionarily conserved and

7 CTP synthase is an ideal model system for addressing thi

8 CTP Synthetase (CtpS) is a universally conserved and ess

9 CTP was a better predictor of myocardial ischemia, with

10 CTP was assessed using the visual perfusion assessment.

11 CTP was performed and K(trans) maps were used to assess

12 CTP:phosphocholine cytidylyltransferase (CCT) catalyzes

13 CTP:phosphocholine cytidylyltransferase (CCT) interconve

14 CTP:phosphocholine cytidylyltransferase (CCT) is a key r

15 CTP:phosphocholine cytidylyltransferase (CCT), an amphit

16 CTP:phosphoethanolamine cytidylyltransferase (Pcyt2) is

17 CTPs were developed for nine cationic metals (Cd, Cr(III

18 is of the X-ray structures revealed that (1) CTP and dCTP bind in a very similar fashion, (2) UTP, in

19 vation of RNR with a mixture of [1'-(3)H]F(2)CTP and [1'-(2)H]F(2)CTP followed by reduction with NaBH

20 sociated with alkylation by the sugar of F(2)CTP and the second with AdoCbl destruction.

21 mixture of [1'-(3)H]F(2)CTP and [1'-(2)H]F(2)CTP followed by reduction with NaBH(4), alkylation with

22 High-field ENDOR studies with [1'-(2)H]F(2)CTP from the reaction quenched at 30 s revealed a radica

23 To determine the fate of [1'-(3)H]F(2)CTP in the latter pathway, the reaction mixture at 2 min

24 of a mechanism of inactivation of RNR by F(2)CTP involving multiple reaction pathways.

25 [1'-(3)H]- and [5-(3)H]F(2)CTP were synthesized and used independently to inactivat

26 Incubation of [1'-(3)H]F(2)CTP with C119S-RNR resulted in 0.3 equiv of sugar being

27 fluoro-2'-deoxycytidine 5'-triphosphate (F(2)CTP) in <2 min.

28 fluoro-2'-deoxycytidine 5'-triphosphate (F(2)CTP).

29 ranone species derived from the sugar of F(2)CTP.

30 enes (PCTA) from their 2-chlorothiophenol (2-CTP) precursor.

31 to predict yields of these pollutants from 2-CTP up to approximately 1200 K, that is, prior to the em

32 (24 weeks treatment); 19 (95%, 78-100) of 20 CTP-B patients (12 weeks treatment); 20 (100%, 86-100) o

33 12 weeks treatment); 20 (100%, 86-100) of 20 CTP-B patients (24 weeks treatment); one (50%, 3-98) of

34 24 weeks of treatment; 17 (85%, 66-96) of 20 CTP-C patients (12 weeks treatment); and 18 (78%, 60-91)

35 was achieved by 20 (87%, 90% CI 70-96) of 23 CTP-B patients with 12 weeks of treatment; 22 (96%, 81-1

36 2 weeks of treatment; 22 (96%, 81-100) of 23 CTP-B patients with 24 weeks of treatment; 17 (85%, 66-9

37 weeks treatment); and 18 (78%, 60-91) of 23 CTP-C patients (24 weeks treatment).

38 (12 weeks treatment); 27 (96%, 84-100) of 28 CTP-A patients (24 weeks treatment); 19 (95%, 78-100) of

39 24 weeks treatment); 30 (100%, 91-100) of 30 CTP-A patients (12 weeks treatment); 27 (96%, 84-100) of

40 (Child-Turcotte-Pugh [CTP] class A, n = 564; CTP class B/C, n = 175), 90% achieved sustained virologi

41 Dgk1p contains a CTP transferase domain that is present in the SEC59-enco

42 Cyclopentenyl cytosine (CPEC), a CTP synthase inhibitor that has been reported previously

43 iments with cyclopentenyl cytosine (CPEC), a CTP synthetase inhibitor and cytosine, suggest that the

44 Following occurrence of a CTP score>/=7, the rate of subsequent events increased t

45 Our recent identification of a CTP-dependent archaeal riboflavin kinase strongly indica

46 patients who had either no cirrhosis; CTP-A, CTP-B, or CTP-C cirrhosis; or fibrosing cholestatic hepa

47 a corresponding SPECT perfusion abnormality, CTP had a sensitivity of 93% and a specificity of 74%.

48 In addition, CTP, UTP and nearly all UDP-activated sugars that serve

49 yl-CTP, inhibit polymerase, whereas 2'-amino-CTP is incorporated.

50 was 16/843 (2%), significantly higher among CTP class B/C versus CTP class A patients (6.4% versus 0

51 CTA (area under the curve [AUC] = 0.844) and CTP + CTA (AUC = 0.845) had comparable per-vessel diagno

52 rates were observed between CTP class A and CTP class B/C patients (94% versus 78%, and 4% versus 14

53 noted that higher concentrations of ATP and CTP (at 2.5 mM or higher) promoted DNA religation by a P

54 Strong sensitivity to both ATP and CTP concentrations occurred in their physiological conce

55 c (sphinganine) lipids, nucleotides (ATP and CTP), N-ethylmaleimide, propranolol, phenylglyoxal, and

56 tive binding than that observed with ATP and CTP.

57 35,000 for misincorporation of UTP, ATP, and CTP opposite CMP in the template, respectively.

58 calcification or artefact, TAG320 + CTA and CTP + CTA provide comparable diagnostic accuracy for fun

59 CTA and CTP were performed in 91 consecutive patients with stent

60 row computed tomography (TAG320) + CTA, and CTP + TAG320 + CTA (multidetector computed tomography-in

61 a destabilization of the R state by CTP and CTP/UTP, consistent with the T and R state crystallograp

62 we demonstrate the excitation of dipolar and CTP resonant modes in metallic nanodimers bridged by pha

63 ing conserved prokaryotic choline kinase and CTP:phosphocholine cytidylyltransferase activities with

64 The DNA motifs and CTP-dependent riboflavin kinase activity of two RbkR pro

65 d apparent K m values for phosphocholine and CTP of 2.29 and 1.21 mM, respectively, in the presence o

66 the intracellular concentrations of UTP and CTP may precisely regulate hCTPS activity.

67 itant depletion of the intracellular UTP and CTP pools.

68 razofurin (inhibits the synthesis of UTP and CTP) were added to SVpzf-infected cells, the yield of vi

69 e, analog nucleotides including GTP, UTP and CTP, do not show serious interferences and this sensor r

70 It can hydrolyze ATP, GTP, UTP, and CTP.

71 S subunits and hydrolyzes ATP, GTP, UTP, and CTP.

72 Exogenously applied CTP caused elevations in [Ca(2+)](cyt) that displayed di

73 ytosine arabinoside (ara-C, cytarabine), ara-CTP, has been investigated and verified.

74 ically, dGTP-activated SAMHD1 hydrolyzes Ara-CTP, which results in a drastic reduction of Ara-CTP in

75 utically active triphosphate metabolite, Ara-CTP, which exerts antileukemic effects, primarily by inh

76 on) over a linear concentration range of ara-CTP (0.05-0.5 microM), and detection is independent of r

77 which results in a drastic reduction of Ara-CTP in leukemic cells.

78 of the NTP, including 2',3'-ddCTP, arabinose-CTP, and 2'-O-methyl-CTP, inhibit polymerase, whereas 2'

79 protein-protein interfaces of the assembled CTP complex.

80 The CCA-adding enzyme [ATP(CTP):tRNA nucleotidyltransferase] adds CCA to the 3' end

81 CCA-adding enzymes [ATP(CTP):tRNA nucleotidyltransferases] add CCA onto the 3' e

82 o model the interactions of myosin with ATP, CTP, UTP, aza-ATP, ITP, and GTP (in decreasing order of

83 d patients with Child-Turcotte-Pugh class B (CTP-B) or CTP-C cirrhosis who had not undergone liver tr

84 Despite similar baseline CTP ischemic core volumes using the previously validated

85 On a per-vessel basis, CTP alone had a sensitivity of 79% and a specificity of

86 a(2+)](cyt) elevations were distinct between CTP and purine nucleotides.

87 VR12 and relapse rates were observed between CTP class A and CTP class B/C patients (94% versus 78%,

88 speed of the HMS operation could allow both CTP isolation and engraftment during a single surgical p

89 (Uridine probably acts by generating both CTP, which can be limiting in phosphatide synthesis, and

90 eceptor to become sensitive to activation by CTP and ADP.

91 pathway for PC biosynthesis was catalyzed by CTP:phosphocholine cytidylyltransferase.

92 The enzyme is inhibited by CTP and can be further inhibited by UTP, although UTP al

93 e transcarbamoylase is feedback inhibited by CTP and UTP in the presence of CTP.

94 ive ATCase regulation by ATP and negative by CTP, with the negative effects of CTP dominating the pos

95 ATP and a destabilization of the R state by CTP and CTP/UTP, consistent with the T and R state cryst

96 A binding activity of RbkR was stimulated by CTP and suppressed by FMN, a product of riboflavin kinas

97 herefore recommend the use of our calculated CTP.

98 We thus calculated CTP values for TiO2 nanoparticles for air, water, and so

99 oproteinases (MMPs) and cysteine cathepsins (CTPs) subsequent to application of a filler-free (Res.A)

100 tation patients who had either no cirrhosis; CTP-A, CTP-B, or CTP-C cirrhosis; or fibrosing cholestat

101 inally a cytidylyltransferase that condenses CTP to generate CMP-pseudaminic acid.

102 argue that the regulatory sites that control CTP synthase function, but not enzymatic activity per se

103 CTA, CTP, and TAG320 were assessed using 320-detector row MDC

104 Patients who underwent CTA, CTP, and FFR assessment on invasive coronary angiography

105 CTA/CTP (7.9 +/- 2.8 mSv) had a significantly lower effectiv

106 ocardial territory was read for combined CTA/CTP.

107 eiver-operating characteristic curve for CTA/CTP (0.82, 95% CI: 0.69 to 0.95) was superior to that fo

108 The per-patient diagnostic accuracy of CTA/CTP for stents (87%, 95% confidence interval [CI]: 78% t

109 udy, utilizing the overexpressed, single-Cys CTP-binding site variants that were functionally reconst

110 otentials (CTP) for nanoparticles and derive CTP values for TiO2 nanoparticles (TiO2-NP) for use in L

111 etween nanodisks and formation of a distinct CTP peak at longer wavelengths (lambda 1.85 mum) far fro

112 Each CTP-enriched cell product was tested using cell culture

113 remains an open question, and more effective CTPs are needed.

114 ed direct inhibition of the cytosolic enzyme CTP:phosphoethanolamine cytidylyltransferase (PCYT2).

115 375575), a specific inhibitor of the enzyme CTP synthetase, induces irreversible growth arrest and s

116 ally reconstituted in liposomes, we examined CTP specificity from both its external and internal surf

117 tem (PDE, adenylate kinase (AK) using excess CTP instead of ATP as substrate, pyruvate kinase (PK), a

118 wild-type CTPS1 or by addition of exogenous CTP or its nucleoside precursor, cytidine.

119 ks treatment); and four (80%, 34-99) of five CTP-C patients (24 weeks treatment).

120 ions to suppress kcat and elevate the Km for CTP.

121 is constants were 156, 17, and 86 microM for CTP, (R)-phosphopantothenate, and L-cysteine, respective

122 n an error-free manner, with specificity for CTP incorporation being essentially the same as for unda

123 Furthermore, CTP has never been validated against the invasive refere

124 amidation of known acceptor molecules (e.g. CTP synthesis).

125 t nucleotide substrates, including ATP, GTP, CTP, UTP, and NAD.

126 lower activity than ATP, PSTK utilizes GTP, CTP, UTP and dATP as phosphate-donors.

127 nt but as an essential nutrient and thus has CTPs of zero.

128 known mycothiazole and a novel heterocyclic, CTP-431 (1).

129 Across metals, the highest CTPs were observed for Cd, Pb, and Zn.

130 0-row computed tomography perfusion imaging (CTP) to detect atherosclerosis causing myocardial ischem

131 us adverse events (SAEs) were more common in CTP class B/C versus CTP class A patients (50% versus 12

132 yers; however, propagation was maintained in CTP-RXP-E-treated cells, although at a slower rate.

133 gesting that the filaments comprise inactive CTP synthase dimers.

134 actions for all parameters tested, including CTP prevalence (CTPs per 10(6) nucleated cells), prolife

135 ement of the alpha phosphate of the incoming CTP, which results from the interaction of C with argini

136 lite prodrug 3-deazauridine (3DUrd) inhibits CTP synthetase upon intracellular conversion to its trip

137 which selectively depletes the intracellular CTP pools.

138 t is near but not overlapping with the known CTP site.

139 ixed inhibitor of the reconstituted Cys-less CTP, with a strong competitive component [i.e., a compet

140 The median CTPs for Cu and Ni with 95% geographic variability inter

141 2',3'-ddCTP, arabinose-CTP, and 2'-O-methyl-CTP, inhibit polymerase, whereas 2'-amino-CTP is incorpo

142 and defining inhibitor of the mitochondrial CTP, is a mixed inhibitor of the reconstituted Cys-less

143 dings in the context of our homology-modeled CTP as it cycles between the outward-facing, occluded, a

144 Combined coronary CTA and myocardial CTP improves diagnosis of CAD and in-stent restenosis in

145 pectrometry and one- and two-dimensional NMR CTP:glucose-1-phosphate cytidylyltransferase, CDP-Glc 4,

146 CTPS) is the rate-limiting enzyme in de novo CTP synthesis and is required for the formation of RNA,

147 Bi Uni Uni Bi Ping-Pong, with the nucleotide CTP binding first and CMP released last.

148 intermediates of the pyrimidine nucleotide, CTP.

149 could now be elicited by other nucleotides (CTP and ADP) that are not normally effective as P2X rece

150 so significantly improved by the addition of CTP (p < 0.001).

151 complexes stall after successful addition of CTP opposite the phenanthriplatin-dG adduct in an error-

152 Addition of CTP or the combination of CTP/UTP to the substrates sign

153 The reversible association of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha)

154 he binding of UTP can enhance the binding of CTP and why UTP binds more tightly in the presence of CT

155 Addition of CTP or the combination of CTP/UTP to the substrates significantly decreased the ra

156 hereas correspondingly low concentrations of CTP or GTP had no negative effects on the magnitude of C

157 sis of G RNA at the lowest concentrations of CTP tested.

158 of these structures is related to control of CTP synthase activity.

159 e soil was introduced into the definition of CTP.

160 We have demonstrated that depletion of CTP induced by cyclopentenyl cytosine (CPEC; NSC 375575)

161 in pah1 pah2 is suppressed by disruption of CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE1 (CCT1), which e

162 egative by CTP, with the negative effects of CTP dominating the positive ones of ATP when both regula

163 Integration of CTP and CTA improves MDCT performance for the detection

164 TPS1-deficient cells had decreased levels of CTP.

165 rovide further insight into the mechanism of CTP-mediated chloroplastic localization, and more import

166 st reactions are observed in the presence of CTP followed by ATP, UTP, and GTP.

167 gistically inhibit ATCase in the presence of CTP, we determined a series of X-ray structures of ATCas

168 inhibited by CTP and UTP in the presence of CTP.

169 hy UTP binds more tightly in the presence of CTP.

170 hat it may be important for the provision of CTP, uridine, and cytidine nucleotides.

171 Recruitment of CTP synthase to filaments and foci can be modulated by m

172 -MB-231 cells were prevented by repletion of CTP through the cytidine salvage pathway.

173 These findings support a predominant role of CTP and ATP in ATCase regulation.

174 t is possible that the tricyclic skeleton of CTP-431 (1) is biosynthetically related to the macrolide

175 the synthesis and conformational studies of CTP mimics, having nonconstrained alpha(3)beta motif, th

176 Our structure-function studies of CTP synthase in Saccharomyces cerevisiae reveal that des

177 Level 1 data regarding the optimal timing of CTP in major colorectal surgery and the incidence of OP-

178 purified recombinant enzyme were its use of CTP as the phosphoryl donor and the absence of a require

179 geographic variability in the calculation of CTPs for terrestrial ecotoxicity of metals.

180 pping from peaks before the establishment of CTPs to nadirs a few years into trading.

181 uitable biomarker for magnetic separation of CTPs from bone marrow aspirates in a canine model.

182 tients with large baseline ischemic cores on CTP undergoing ET with the outcomes of matched controls

183 baseline ischemic core greater than 50 mL on CTP at a tertiary care center from May 1, 2011, through

184 ed for age, baseline ischemic core volume on CTP, and glucose levels.

185 Based on this inference, an optimized CTP, named RC2, was constructed.

186 I) was then undertaken to define the optimum CTP thresholds for the ischemic core.

187 r 100-fold GTP-specificity over GDP, ATP, or CTP and was used to develop a heterogeneous time-resolve

188 with Child-Turcotte-Pugh class B (CTP-B) or CTP-C cirrhosis who had not undergone liver transplantat

189 ho had either no cirrhosis; CTP-A, CTP-B, or CTP-C cirrhosis; or fibrosing cholestatic hepatitis.

190 (AUC = 0.91) was superior to TAG320 + CTA or CTP + CTA (p = 0.01).

191 fashion, (2) UTP, in the presence of dCTP or CTP, binds at a site that does not overlap the CTP/dCTP

192 e sensitive to high concentrations of UTP or CTP.

193 Mismatched ATP, UTP, or CTP could mediate excision of 3'-terminal CMP to generat

194 articipants who developed clinical outcomes [CTP > 7, ascites, encephalopathy, variceal bleeding, SBP

195 nated to a cytoplasmic transduction peptide (CTP) for cytoplasmic translocation (CTP-RXP-E).

196 Various chloroplast transit peptides (CTP) have been used to successfully target some foreign

197 the external and internal binding sites (per CTP monomer) before transport.

198 angiography (CTA) and stress-rest perfusion (CTP) with cardiac magnetic resonance myocardial perfusio

199 Computed tomographic perfusion (CTP) imaging may identify a subset of patients with larg

200 y of combined computed tomography perfusion (CTP) + computed tomography angiography (CTA), translumin

201 n rest/stress computed tomography perfusion (CTP) and SPECT-MPI, but the value of resting CTP (rCTP)

202 derived from computed tomography perfusion (CTP) imaging, can predict hemorrhagic transformation (HT

203 Computed Tomography Perfusion (CTP) is an additional method to the conventional Compute

204 same baseline computed tomography perfusion (CTP) ischemic core threshold to predict infarction as th

205 ng myocardial computed tomography perfusion (CTP) to computed tomography angiography (CTA) improves d

206 ages for CTA, computed tomography perfusion (CTP), and single-photon emission computed tomography (SP

207 fferent dipolar and charge transfer plasmon (CTP) resonances, respectively.

208 Preoperative and postoperative CTP are equally safe in protecting against VTE.

209 randomized to preoperative or postoperative CTP with 5000 units of subcutaneous heparin.

210 ference in preoperative versus postoperative CTP with respect to early postoperative DVT [3/184 (1.6%

211 factors or comparative toxicity potentials (CTP) for nanoparticles and derive CTP values for TiO2 na

212 Comparative toxicity potentials (CTP), in life cycle impact assessment also known as char

213 ated marine comparative toxicity potentials (CTPs) or ecotoxicity characterization factors for metals

214 arrangement of the S. pombe Ccq1-Tpz1-Poz1 (CTP) complex.

215 CTP (1%; p < 0.001; severe angina precluded CTP in 1 case).

216 -based analysis of coregistered pretreatment CTP and 24-hour diffusion-weighted imaging (DWI) was the

217 parameters tested, including CTP prevalence (CTPs per 10(6) nucleated cells), proliferation by colony

218 values for the substrate UTP and the product CTP, respectively, were close to their physiological con

219 ation inhibits activity, and CtpS's product, CTP, induces assembly.

220 Connective tissue progenitors (CTPs) are a promising therapeutic agent for bone repair.

221 tween innovation and cap-and-trade programs (CTPs)--the world's most prominent climate policy instrum

222 the carboxyl-terminal processing proteases (CTPs).

223 The mitochondrial citrate transport protein (CTP) is critical to energy metabolism in eukaryotic cell

224 ast mitochondrial citrate transport protein (CTP).

225 Child-Turcotte-Pugh (CTP) and Model for End-stage Liver Disease (MELD) scores

226 ith decompensation were Child-Turcotte-Pugh (CTP) class B versus A (hazard ratio [HR] 7.7; 95% CI 3.3

227 Child-Turcotte-Pugh (CTP) score>/=7 was the most common first outcome, follow

228 survival until day 60; Child-Turcotte-Pugh (CTP), Model for End-Stage Liver Disease (MELD), and Sequ

229 atients with cirrhosis (Child-Turcotte-Pugh [CTP] class A, n = 564; CTP class B/C, n = 175), 90% achi

230 Treatment with G-CSF also reduced CTP scores in group A by a median of 33.3% compared with

231 for 2 months; it also significantly reduces CTP, MELD, and SOFA scores and prevents the development

232 th and metabolic regulation without reducing CTP levels.

233 future market conditions under the relevant CTPs.

234 CTP) and SPECT-MPI, but the value of resting CTP (rCTP) in acute chest pain triage remains unclear.

235 oroplasts, but for other proteins these same CTPs have reduced localization efficiencies or fail comp

236 ry review, with a Child-Turcotte-Pugh score (CTP) of A or B, ECOG performance status of 0 to 2, no ex

237 beta-turn to gamma-turn structure in similar CTPs by inverting the chirality of beta(3) carbon in C-l

238 ine N-methyltransferase and hepatic-specific CTP:phosphocholine cytidylyltransferase alpha.

239 el CT techniques, including adenosine stress CTP and TAG320, may improve the diagnostic accuracy of C

240 l was nondiagnostic on CTA, adenosine stress CTP in the corresponding myocardial territory was read f

241 cluded 320-CTA, followed by adenosine stress CTP.

242 ugh empirical evidence drawn from successful CTPs for sulfur dioxide and nitrogen oxide control.

243 in the CDP-choline pathway for PC synthesis, CTP:phosphocholine cytidylyltransferase alpha (CCTalpha)

244 erged to establish the cyclic tetrapeptides (CTPs) as the primary determinant of both potency and sel

245 Designing cyclic tetrapeptides (CTPs), which fold into desired structures, is often a ch

246 ast 2 orders of magnitude more abundant than CTP in liver extracts.

247 with 2-fold higher catalytic efficiency than CTP and efficiently polymerizes additional NTPs onto the

248 of UTP stabilizes the T state even more than CTP alone.

249 We conclude that CTP depletion and the resulting nucleolar stress respons

250 Mechanistic studies revealed that CTP depletion induced a rapid translocation of nucleolar

251 Single turnover kinetic studies showed that CTP is incorporated with apparent K(d) and k(pol) values

252 The CTP score was A for 79.5% of patients and B for 15.7%; 4

253 l CT and MRI methods, can be acquired by the CTP method.

254 ognostic information to that provided by the CTP score.

255 k1 diacylglycerol (DAG) kinase catalyzes the CTP-dependent phosphorylation of DAG to form phosphatidi

256 -encoded diacylglycerol kinase catalyzes the CTP-dependent phosphorylation of diacylglycerol to form

257 sis pathway that depends on two enzymes, the CTP synthases (or synthetases) 1 and 2 (CTPS1 with CTPS2

258 ariability of 3.5 orders of magnitude in the CTP of Cu is mainly associated with the variability in s

259 variability of 3 orders of magnitude in the CTP of Ni can mainly be explained by differences in pore

260 glimpse into the architectural design of the CTP complex and reveals unique interactions that are imp

261 scription factor Gln3 or inactivation of the CTP synthetase Ura7 both resulted in the activation of t

262 he first purely competitive inhibitor of the CTP.

263 ransplantation, is high, especially once the CTP score reaches at least 7.

264 P, binds at a site that does not overlap the CTP/dCTP site, and (3) the triphosphates of the two nucl

265 idues comprising the more external site, the CTP becomes less selective for citrate with numerous ext

266 Previously, we showed that the CTP contains at least two substrate-binding sites.

267 The results showed that the CTP of a specific metal varies 3-4 orders of magnitude a

268 Deletion analysis showed that the CTP transferase domain was sufficient for diacylglycerol

269 and G184A) of conserved residues within the CTP transferase domain caused a loss of diacylglycerol k

270 mutants, thereby confirming that with these CTP variants, K(m) approximates the K(d) (for citrate) a

271 le shows that before trading began for these CTPs, analysts overestimated the value of allowances in

272 l %) and saturation kinetics with respect to CTP (apparent K(m) = 0.3 mm).

273 peptide (CTP) for cytoplasmic translocation (CTP-RXP-E).

274 The nucleotide cytidine 5' triphosphate (CTP) is a precursor required for the metabolism of DNA,

275 de specificity for cytidine 5'-triphosphate (CTP) analogous to that seen for bifunctional PPCS expres

276 e, l-cysteine, and cytidine-5'-triphosphate (CTP) and has been shown to be essential for growth and s

277 t incorporation of cytidine 5'-triphosphate (CTP) at position 76 arises from improper placement of th

278 phosphocholine and cytidine 5'-triphosphate (CTP) to CDP-choline for the eventual synthesis of phosph

279 se pyrophosphorylase, cytidine triphosphate (CTP) synthase, or subunits of the eIF2/2B translation fa

280 riphosphate (ATP) and Cytosine triphosphate (CTP) that are incorporated into the primer, pppACCA.

281 (24 weeks treatment); one (50%, 3-98) of two CTP-C patients (12 weeks treatment); and four (80%, 34-9

282 The P. aeruginosa genome encodes two CTPs annotated as PA3257/Prc and PA5134/CtpA in strain P

283 The enzyme represents a unique CTP-dependent family of kinases.

284 is a unique diacylglycerol kinase that uses CTP, instead of ATP, to generate phosphatidate.

285 ants, and animals, the yeast enzyme utilizes CTP, instead of ATP, as the phosphate donor in the react

286 iporter Npt2(Ct), which transports GTP, UTP, CTP, and ATP.

287 f SG RNA at the lowest concentrations of UTP/CTP and that the single SVcpc mutation enhances the synt

288 As the UTP/CTP concentrations were increased, the SVpzf system, in

289 viral RNA synthesis as a function of the UTP/CTP concentrations.

290 etal artifacts [75%] or motion [25%]) versus CTP (1%; p < 0.001; severe angina precluded CTP in 1 cas

291 Es) were more common in CTP class B/C versus CTP class A patients (50% versus 12%, respectively; P <

292 nificantly higher among CTP class B/C versus CTP class A patients (6.4% versus 0.9%; P < 0.001).

293 a acidophilum was determined in complex with CTP and its DNA operator revealing key residues for oper

294 o found to catalyze cytidylation of FMN with CTP, making the modified FAD, flavin cytidine dinucleoti

295 to the superfusate of monolayers loaded with CTP-RXP-E, action potential propagation was maintained,

296 , while large differences were observed with CTP values for TiO2 nanoparticles published in earlier s

297 e course of the PPCS-catalyzed reaction with CTP and L-cysteine, was monitored by (31)P NMR spectrosc

298 n of the Escherichia coli class III RNR with CTP (substrate) and ATP (allosteric effector) in the abs

299 nstead of GTP, and initiate transcripts with CTP.

300 s appeared plausible after benchmarking with CTPs for other nanoparticles and substances present in t

301 i.e., a negative cooperative effect of ATP x CTP).