ライフサイエンスコーパス: CXC chemokine receptor 4

1 growth factor receptor and G-protein-coupled CXC chemokine receptor 4.

2 ceptor 5 (CCR5), whereas 84%-99% coexpressed CXC chemokine receptor 4.

3 nterleukin-10-induced apoptosis, all through CXC chemokine receptor-4.

4 We coinfected rhesus macaques with CXC chemokine receptor 4- and CC chemokine receptor 5-sp

5 a promising protein therapeutic and implies CXC chemokine receptor 4 as a drug target after polytrau

6 receptor LESTR, which we therefore designate CXC-chemokine receptor-4 (CXCR-4).

7 ow that extracellular ubiquitin is a natural CXC chemokine receptor 4 (CXCR4 and CD184) agonist.

8 demonstrates cell surface expression of both CXC chemokine receptor 4 (CXCR4) and CC chemokine recept

9 The CXC chemokine receptor 4 (CXCR4) and its ligand, stromal

10 CCR5 and CXC chemokine receptor 4 (CXCR4) are coreceptors for CD4

11 ll-derived factor-1 (SDF-1) and its receptor CXC chemokine receptor 4 (CXCR4) are important regulator

12 We identify CXC chemokine receptor 4 (CXCR4) as a receptor used by a

13 The CXC chemokine receptor 4 (CXCR4) contributes to the meta

14 romal cell-derived factor 1 and its receptor CXC chemokine receptor 4 (CXCR4) critically mediate the

15 The CXC chemokine receptor 4 (CXCR4) for the chemokine (C-X-

16 Activation of the CXC chemokine receptor 4 (CXCR4) in Cajal-Retzius cells

17 terferes with the expression and function of CXC chemokine receptor 4 (CXCR4) in CD4+ T lymphocytes.

18 have investigated the expression of surface CXC chemokine receptor 4 (CXCR4) in enriched populations

19 east cancer, GnRH in ovarian carcinomas, and CXC chemokine receptor 4 (CXCR4) in multiple malignancie

20 CXC chemokine receptor 4 (CXCR4) is a cell surface recep

21 CXC chemokine receptor 4 (CXCR4) is a co-receptor for hu

22 CXC chemokine receptor 4 (CXCR4) is a G protein-coupled

23 The human CXC chemokine receptor 4 (CXCR4) is a receptor for the c

24 38+ cells in the blood, higher leukemic cell CXC chemokine receptor 4 (CXCR4) levels, and increased r

25 al use of CC chemokine receptor 5 (CCR5) and CXC chemokine receptor 4 (CXCR4) may be intimately invol

26 Enhancement of CXC chemokine receptor 4 (CXCR4) mRNA expression was obs

27 CXC chemokine receptor 4 (CXCR4) plays a role in the dev

28 crophage-tropic coreceptor for HIV-1 whereas CXC chemokine receptor 4 (CXCR4) serves the counterpart

29 The stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor 4 (CXCR4) signaling axis appears

30 lls expressed elevated levels of CD95, CD25, CXC chemokine receptor 4 (CXCR4), and CC chemokine recep

31 CXC chemokine receptor 4 (CXCR4), initially linked with

32 The chemokine receptor, CXC chemokine receptor 4 (CXCR4), is selective for CXC c

33 NSCs express CXC chemokine receptor 4 (CXCR4), the cognate receptor f

34 The receptor for SDF-1, CXC chemokine receptor 4 (CXCR4), was found to be expres

35 gous to the V3 loop of HIV-1, which binds to CXC chemokine receptor 4 (CXCR4), we hypothesized that B

36 ations covering all 352 residues of the GPCR CXC chemokine receptor 4 (CXCR4), we identified 41 amino

37 , indicating that PTEN was not requisite for CXC chemokine receptor 4 (CXCR4)-mediated chemotaxis of

38 erived factor-1 alpha (CXCL12/SDF-1) via the CXC chemokine receptor 4 (CXCR4).

39 cluding integrin beta1, integrin alpha4, and CXC chemokine receptor 4 (CXCR4).

40 hereas 26%-73% of cells coexpressed CCR5 and CXC chemokine receptor 4 (CXCR4).

41 or, either CC chemokine receptor 5 (CCR5) or CXC chemokine receptor 4 (CXCR4).

42 1alpha (SDF-1alpha) binding to its receptor, CXC chemokine receptor 4 (CXCR4).

43 al derived factor-1alpha, the ligand for the CXC chemokine receptor 4 (CXCR4).

44 gp120 with CC chemokine receptor 5 (CCR5) or CXC chemokine receptor 4 (CXCR4).

45 we reported that human RMS cells express the CXC chemokine receptor-4 (CXCR4) and postulated a role f

46 howed that inducible knockdown of endogenous CXC chemokine receptor-4 (CXCR4) gene expression in brea

47 romal cell-derived factor-1 and its receptor CXC chemokine receptor-4 (CXCR4) have received considera

48 tic parental cells (686LN-Ps), we found that CXC chemokine receptor-4 (CXCR4) mRNA levels were signif

49 the bone marrow via cross talk with the SDF-CXC chemokine receptor-4 (CXCR4) signaling axis.

50 Most importantly, BDNF reduced the levels of CXC chemokine receptor-4 (CXCR4), a receptor that mediat

51 d, these cells expressed substantial surface CXC chemokine receptor-4 (CXCR4), and CXCL12 stimulation

52 We hypothesized that the CXC chemokine receptor-4 (CXCR4)-stromal-derived factor-

53 A chimeric protein consisting of CXC-chemokine receptor 4 (CXCR4) and the green fluoresce

54 CXC-chemokine receptor 4 (CXCR4) is a G protein-coupled

55 CXC-chemokine receptor 4 (CXCR4) regulates the retention

56 The antagonism of CXC-chemokine receptor 4 (CXCR4) with AMD3100 improves c

57 iae lacking FimCDE fail to interact with the CXC-chemokine receptor 4 (CXCR4), and bacteria expressin

58 , up-regulates the surface expression of the CXC-chemokine receptor 4 (CXCR4), but not of the CC-chem

59 -derived factor (SDF)-1alpha (the ligand for CXC chemokine receptor 4 [CXCR4]) did not affect T(GFP)

60 nfection, which was associated with CCR5 and CXC chemokine receptor 4 down-regulation.

61 ells with 12G5, an antibody specific for the CXC chemokine receptor-4, eliminates this response indic

62 ral differentiation, we observed that CXCR4 (CXC chemokine receptor-4) expressing central nervous sys

63 oreceptor, whereas T cell-tropic strains use CXC chemokine receptor-4 for entry.

64 e the infectivity of HIV-1 isolates that use CXC-chemokine receptor 4 for entry.

65 cell-derived factor 1alpha and its receptor CXC chemokine receptor 4 in beta-selection.

66 le describes the transient expression of the CXC chemokine receptor-4 in Xenopus laevis melanophores

67 Disrupting homing dynamics with a CXC chemokine receptor 4 inhibitor reduced the formation

68 These results indicate that SDF-1 and CXC chemokine receptor-4 interactions not only play a ro

69 Plasma levels of the cognate CXC chemokine receptor 4 ligand stromal cell-derived fac

70 a-mediated costimulation was blocked by anti-CXC chemokine receptor-4 mAb.

71 vels and corresponding surface expression of CXC chemokine receptor 4 on clonal PCs, suggesting that

72 eramide but not for CC-chemokine receptor 5, CXC-chemokine receptor 4, or CD4.

73 s, such as protease-activated receptor 1 and CXC chemokine receptor 4, RGS4 disrupted Rac1-dependent

74 bone marrow; in particular, the role of the CXC chemokine receptor 4/stromal-derived factor 1 axis,

75 Because the CXC chemokine receptor-4/stromal derived factor-1 (CXCR4

76 The HIV envelope glycoprotein interacts with CXC chemokine receptor 4 to activate the lysosomal degra

77 gp120 coupled CXCR4 (CXC chemokine receptor 4) to induce NADPH oxidase-mediat

78 upregulated in tissues infected ex vivo with CXC chemokine receptor 4-tropic but not CCR5-tropic HIV-

79 stem cell mobilizer or its receptor, CXCR4 (CXC chemokine receptor 4), would attenuate and reverse h