ライフサイエンスコーパス: Cal

1 Cal PA-XFS expressed significantly less PA-X than Cal wi

2 Cal WT, but not Cal PA-XFS, induced degradation of host

3 Cal- modulin was found to interact strongly with the cyt

4 the Iron/Roman period ( approximately 2,000 Cal y B.P.), with no subsequent directional change.

5 in the Neolithic ( approximately 4,000-7,000 Cal y B.P.) and continues through the Iron/Roman period

6 PA from the pH1N1 virus A/California/04/09 (Cal) strongly enhances activity of an otherwise avian po

7 ly different Ca2+ indicators, such as OGB-1, Cal-590 can be readily used for simultaneous multicolor

8 se component or NS1 of A/California/04/2009 (Cal) and found that PA has a significant impact on the e

9 ex of the pH1N1 strain A/California/04/2009 (Cal) is highly active in mammalian 293T cells, despite t

10 nd after receiving the A/California/04/2009 (Cal/09) vaccine between October 2009 and January 2010.

11 demic influenza virus, A/California/04/2009 (Cal/09).

12 t of neurons that stain for calbindin D-28K (Cal), a calcium-binding protein involved in regulating n

13 roximately 11,550 yBP ( approximately 13,390 Cal years) at "El Fin del Mundo," an archaeological site

14 DB age range for this event of 12,835-12,735 Cal B.P. at 95% probability.

15 e onset of the YD climatic episode at 12,800 Cal B.P.

16 at the Younger Dryas boundary (YDB) (12,800 Cal B.P.).

17 used by pandemic virus A/California/04/09 (A/Cal; H1N1).

18 by DI virus, ferrets formed high levels of A/Cal-specific serum haemagglutination-inhibiting antibodi

19 d in nasal washes following infection with A/Cal, consistent with its amelioration of clinical diseas

20 nd were solidly immune to rechallenge with A/Cal.

21 sed BSO+AUR-induced cell killing in FaDu and Cal-27 cells, while catalase and selenium supplementatio

22 In both Cal and WSN viruses, PA-X showed a stronger effect than

23 ion falls within the K pathway as defined by Cal content.

24 y 13,300 to approximately 12,800 calibrated (Cal) years] made distinctive "Clovis" artifacts.

25 A recombinant WSN containing Cal PA showed enhanced host protein synthesis shutoff an

26 V683T/A684S, which are involved in enhanced Cal polymerase activity at low temperature.

27 vival compared to either drug alone in FaDu, Cal-27 and SCC-25 HNSCC cells in vitro and in vivo in Ca

28 BSO+AUR also significantly sensitized FaDu, Cal-27, SCC-25 and SQ20B cells to cell killing induced b

29 n the dLGN that were also immunoreactive for Cal varied from less than 40% to over 80%, indicating th

30 elial cell monolayers with supernatants from Cal-stimulated mast cells resulted in upregulation of th

31 frameshift motif in the polymerase PA gene (Cal PA-XFS).

32 Sera derived from SAM(H1-Cal)-immunized animals were not cross-reactive with the

33 nstrated considerable susceptibility to H1N1 Cal/04/09 infection, whereas FluMist-vaccinated mice had

34 cificity shared with the 2009 pandemic H1N1 (Cal/04) hemagglutinin.

35 ween the pandemic A/California/04/09 (H1N1) (Cal/09) virus and another H1N1 strain, A/Puerto Rico/8/3

36 influenza A virus, A/California/04/09 (H1N1, Cal), containing mutations at the frameshift motif in th

37 PB2, is a major contributing factor to high Cal polymerase activity in 293T cells.

38 tis serovars D (UW-3/Cx), E (Bour), or F (IC-Cal-3) or Chlamydia muridarum strain Nigg II using CpG-1

39 and neutralizing antibodies were produced in Cal PA-XFS-infected mice than in Cal WT-infected mice, d

40 ing the presence of unidentified residues in Cal PB2 that are required for efficient growth at low te

41 produced in Cal PA-XFS-infected mice than in Cal WT-infected mice, despite the lower level of virus r

42 d SCC-25 HNSCC cells in vitro and in vivo in Cal-27 xenografts.

43 d the red-shifted fluorescent Ca2+ indicator Cal-590 for deep tissue experiments in the mouse cortex

44 conclude that the red-shifted Ca2+ indicator Cal-590 is well suited for in vivo two-photon Ca2+ imagi

45 The p110delta-specific inhibitor, Cal-101, and small interfering RNA-mediated knockdown of

46 In this animal, large, intensely Cal-immunoreactive neurons were found scattered througho

47 Around 10.7-10.2 ka Cal BP (early Pre-Pottery Neolithic B), the predominant

48 nd late Pre-Pottery Neolithic B (10.2-8.3 ka Cal BP).

49 have implications for future satellite lidar Cal/Val efforts, because planned satellite lidars measur

50 Meaningful Cal/Val requires intercomparison data sets with small en

51 derable along-track averaging for meaningful Cal/Val.

52 mber of days subjects were eligible for Medi-Cal).

53 at least 5 years old, and had Medicaid (Medi-Cal in California), Medicare, private, or no insurance w

54 sociated with white race, and Medicaid (Medi-Cal) and private insurance.

55 d claims data from California Medicaid (Medi-Cal).

56 resent a Medicare card amounts based on Medi-Cal rates.

57 cipating in the state Medicaid program (Medi-Cal) to charge customers who present a Medicare card amo

58 Moreover, Cal WT inhibited beta interferon (IFN-beta) expression a

59 Cal WT, but not Cal PA-XFS, induced degradation of host beta-actin mRNA

60 that, despite the relatively low affinity of Cal-590 for Ca2+ (Kd=561 nM), single-action potential-ev

61 complexes containing various combinations of Cal and avian influenza virus A/chicken/Nanchang/3-120/0

62 also demonstrated that, while the growth of Cal PA-XFS was attenuated in the lungs of infected anima

63 An additional introduction of Cal PB2 enhanced activity at 34 degrees C, suggesting th

64 led neuron and the surrounding population of Cal-590-labeled cells were recorded simultaneously on tw

65 nea pig model to understand which segment of Cal/09 virus conferred transmissibility to the poorly tr

66 with the acetoxymethyl (AM) ester version of Cal-590, combined two-photon imaging and cell-attached r

67 In particular, Cal PA significantly activates the otherwise inactive Na

68 The growth of recombinant Cal containing PB2 with Nan residues 271T/661V/683V/684A

69 fferent viruses (recombinant wild-type [rWT] Cal/09 and the 66N and 66S viruses) did not result in si

70 a A virus A/California/7/2009 (H1N1) strain (Cal) were protected from a lethal challenge with the het

71 We present a dual-protein switch system, Cal-Light, that translates neuronal-activity-mediated ca

72 expression and replicated more rapidly than Cal PA-XFS in human respiratory cells.

73 ant induced a stronger humoral response than Cal WT.

74 A-XFS expressed significantly less PA-X than Cal wild type (WT).

75 We demonstrate that Cal-590 is also suited for multicolor functional imaging

76 (Nan) by reporter gene assay indicates that Cal PA, but not PB2, is a major contributing factor to h

77 tured neurons and brain slices, we show that Cal-Light drives expression of the reporter EGFP with hi

78 eterogeneous in nature and also suggest that Cal content may be a critical feature of the pathway by

79 d by the empirical relationship given by the Cal Tech group, but the strength of these should be redu

80 y demonstrates that PB1-F2 expression by the Cal/09 virus modulates the immune response to infection

81 336M contribute to enhanced activity of the Cal polymerase.

82 Delivery of the Cal-Light components to the motor cortex of mice by vira

83 The data showed that the M segment of the Cal/09 virus promoted aerosol transmissibility to recomb

84 tant swine virus, containing segments of the Cal/09 virus.

85 who received either the NJ/76 vaccine or the Cal/09 vaccine experienced a robust boost in HA stalk-re

86 ng site-directed mutagenesis showed that the Cal PA residues 85I, 186S, and 336M contribute to enhanc

87 To see whether the Cal-immunoreactive dLGN population might potentially pla

88 Thus, Cal-Light enables dissection of neural circuits underlyi

89 ical target may be systematically related to Cal content in the geniculo-extrastriate projection.

90 ve addressed this question by generating two Cal/09 viruses with productive PB1-F2 open reading frame

91 nces in symptoms of infection with wild-type Cal/09 versus the 66N or 66S virus variant.

92 By using Cal-Light to drive expression of the inhibitory receptor

93 Several Calibration/Validation (Cal/Val) studies for CALIOP conducted with ground-based

94 ouble-labeling techniques to examine whether Cal content characterizes all or a subset of neurons mak

95 Mice infected with Cal PA-XFS had significantly lower levels of viral growt

96 mRNA in their lungs than mice infected with Cal WT.

97 s been observed in individuals infected with Cal/09.

98 Paleolithic [11,000-33,000 calibrated years (Cal y) B.P.] through the 20th century.