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1 ing behavior of the smooth dogfish (Mustelus canis).
2 s, Epidermophyton floccosum, and Microsporum canis.
3 y 10% are conserved in the more divergent T. canis.
4 nant major outer membrane P30 proteins of E. canis.
5 ocalized mainly on the morula membrane of E. canis.
6 eeks in dogs experimentally infected with E. canis.
7 ly in the periplasm of E. chaffeensis and E. canis.
8 the isolates are most closely related to S. canis.
9 16 with a Bartonella species, and 7 with B. canis.
10 ntracellular bacterium closely related to E. canis.
11 specimens strongly recognized the rP30 of E. canis.
12 ontained a partial 30-kDa protein gene of E. canis.
13 tions of Ehrlichia chaffeensis and Ehrlichia canis.
14 f E. chaffeensis, and a 30-kDa protein of E. canis.
15 and the parasitic nematode of dogs, Toxocara canis.
16 s and the complete TR (24 amino acids) in E. canis.
17 m types were observed, including one from S. canis.
18 samples were positive for a new strain of E. canis.
19 philum, Ehrlichia chaffeensis, and Ehrlichia canis.
20 the 22 samples that were IFA positive for E. canis, 100% reacted with rP43, 96% reacted with rP28, an
21 rlichia chaffeensis (1,644 bp) and Ehrlichia canis (2,064 bp) encode proteins of 548 to 688 amino aci
23 re divided into four clusters and the two E. canis 30-kDa proteins are closely related but that the t
24 22 persons), C. meleagridis (17 persons), C. canis (6 persons), C. felis (6 persons), and C. suis (1
25 esults, 15 dogs were infected with Ehrlichia canis, 9 with Ehrlichia chaffeensis, 8 with Ehrlichia ew
26 e proteins in E. chaffeensis (75-kDa) and E. canis (95-kD) whole-cell lysates and supernatants were i
31 ion identified the isolates as Streptococcus canis, an organism normally associated with animal hosts
33 associated with C. hominis and C. parvum; C. canis and C. felis are responsible for only a small numb
39 ence of a single copy of the mmpA gene in E. canis and Ehrlichia chaffeensis but not in the human gra
40 the cytoplasm of the reticulate forms of E. canis and Ehrlichia chaffeensis but was notably found on
42 Da major immunoreactive protein (gp19) of E. canis and identified the corresponding TR-containing ort
43 he major immunoreactive 36-kDa protein of E. canis and the corresponding ortholog of E. chaffeensis (
44 experimentally or naturally infected with E. canis and were previously demonstrated to contain antibo
45 skate Raja erinacea and the dogfish Mustelus canis), and a jawless fish (the lamprey Petromyzon marin
46 affeensis, < or =67.3% identity to P30 of E. canis, and < or =63.1% identity to MAP1 of C. ruminantiu
47 oreactive to an Ehrlichia sp., 16 to Babesia canis, and 25 to Bartonella vinsonii, and 22 seroconvert
48 pe), B. canis subsp. vogeli, B. canis subsp. canis, and B. canis subsp. rossi DNA in blood samples fr
49 pe), B. canis subsp. vogeli, B. canis subsp. canis, and B. canis subsp. rossi DNA in canine blood sam
51 marine mammal isolates (no species name), B. canis, and B. suis, confirmed that all but the latter tw
53 pathogens, Ehrlichia chaffeensis, Ehrlichia canis, and Cowdria ruminantium, that have multiple hyper
54 tested (Anaplasma phagocytophilum, Ehrlichia canis, and Rickettsia rickettsii), but the sample was hi
55 mans: Ehrlichia chaffeensis, E. sennetsu, E. canis, and the agent of human granulocytic ehrlichiosis.
56 acter bilis, one clustered with Helicobacter canis, and the remaining pattern was closely related to
57 genes from Neosartorya fischeri, Microsporum canis, and Trichophyton tonsurans were shown to be able
59 tions between rP30 and the whole purified E. canis antigen were compared in the dot immunoblot assay.
60 festations in dogs seroreactive to Ehrlichia canis antigens by indirect immunofluorescent antibody te
61 T-helper 1-type response was elicited to E. canis antigens consisting of immunoglobulin G2 antibodie
62 dies that reacted with E. chaffeensis and E. canis antigens in a pattern different from that of human
63 quantity identified major immunoreactive E. canis antigens recognized early in the infection as the
64 ecific primers, sick dogs seroreactive to E. canis antigens were determined to be infected with four
66 ion process, the structure of Bc28.1 from B. canis appears unrelated to the previously published stru
67 are needed to determine the importance of H. canis as a primary enteric pathogen in cats and the role
68 g and 16S rRNA gene sequencing identified S. canis associated with ulcer infections in dog owners.
69 choeri CCUG 48324(T), 97.9% similarity to S. canis ATCC 43496(T), and 97.8% similarity to S. ictaluri
71 k-transmitted pathogens, including Ehrlichia canis, Babesia canis, Babesia gibsonii, or spotted fever
72 athogens, including Ehrlichia canis, Babesia canis, Babesia gibsonii, or spotted fever group ricketts
78 ehrlichiosis cases that were positive for E. canis by immunofluorescent antibody test and in various
80 iated with diarrhea, only infections with C. canis, C. felis, and subtype family Id of C. hominis wer
82 Streptococcus dysgalactiae and Streptococcus canis cannot be distinguished when only Lancefield typin
86 on of the remaining paralogs was lower in E. canis cultivated in dog monocyte cell line DH82 at 25 de
87 lts were correct, except for one Microsporum canis culture containing two colony variants, which coul
88 rlichia chaffeensis and p30 gene locus of E. canis despite marked divergence between genera in the st
89 a's largest terrestrial predator, the dingo (Canis dingo), could be a driver of shrub encroachment in
93 cluding Anaplasma phagocytophilum, Ehrlichia canis, E. chaffeensis, E. ewingii, Rickettsia rickettsii
94 Coinfection with three Ehrlichia species (E. canis, E. ewingii, and E. equi) was documented for one d
96 hia phagocytophila but not against Ehrlichia canis, Ehrlichia ewingii, B. burgdorferi, or Coxiella bu
97 iptional activity of a five gene locus in E. canis encoding homologous, but non-identical, p28 genes.
98 ed MmpA was cloned by screening an Ehrlichia canis expression library with convalescent dog sera, whi
103 ously neglected species - domesticated dogs (Canis familiaris) - may allow researchers to do just tha
105 in bark frequency and context between dogs (Canis familiaris) and wolves (Canis lupus) has led some
106 in behavioural tendency in the domestic dog (Canis familiaris) are well established, the phenomenon w
109 traits and the skeleton of the domestic dog (Canis familiaris) is arguably the best system in which t
111 y draft genome sequence of the domestic dog (Canis familiaris), together with a dense map of single n
112 h is familiar and relevant to domestic dogs (Canis familiaris), who are known to perceive both segmen
114 acterized in recently available genomes from Canis familiaris, Macaca mulatta, P. troglodytes and Rat
115 iants (CNVs) in the modern domesticated dog, Canis familiaris, which exhibits considerable morphologi
116 , a disjunctive syllogism), task-naive dogs (Canis familiaris; n=19) and 4- to 6-year-old children (H
117 nvestigated by comparing Can f 1 (major dog [Canis familiaris] allergen) levels in hair and coat samp
118 predicted three-dimensional structure of E. canis Fbp demonstrated conservation of important Fbp fam
121 The identification of two isolates of S. canis from a relatively small sample set suggests that t
124 Carbohydrate profiles differentiated B. canis from the other three Brucella species due to the a
125 cleotide sequences from the unique Ehrlichia canis gene, p30, to facilitate studies that require moni
126 plete genome sequencing revealed that the E. canis genome consists of a single circular chromosome of
130 ssay is a highly discriminatory assay for B. canis genotyping, and can serve as a useful molecular ep
136 lated synthetic peptide repeat units from E. canis gp36 and E. chaffeensis gp47 were substantially le
138 t signals from eight other helicobacters (H. canis, H. cineadi, H. felis, H. mustelae, H. nemestrinae
139 humans, the other five being H. pullorum, H. canis, "H. rappini," H. fennelliae, and H. cinaedi.
140 at units, and the 140-kDa protein gene of E. canis has 14 nearly identical, tandemly arranged 108-bp
142 it is not likely a primary neuropathogen, M. canis has the capacity to influence meningoencephalitis
145 major merozoite surface antigens of Babesia canis have been described as a 28-kDa membrane protein f
146 pp. were identified from three (Helicobacter canis, Helicobacter winghamensis, and MIT 99-5504).
149 ELISA format using 141 serum samples from E. canis immunofluorescent antibody (IFA)-positive and IFA-
157 study revealed transcription of p30-10 by E. canis in naturally infected ticks and sequence conservat
158 rom nondiarrheic cats, the causal role of H. canis in producing the diarrhea could not be proven.
161 whether dogs and ticks are infected with E. canis in Venezuela and, if so, whether this is the same
163 ified in Ehrlichia chaffeensis and Ehrlichia canis, including three molecularly and immunologically c
164 iptionally active in in-vitro cultures of E. canis incubated at the vertebrate host (37 degrees C) an
165 s were detected by Northern blotting from E. canis infected DH82 cells, indicating that the genes are
167 sb) proteins were recognized by sera from E. canis-infected dogs but not from E. chaffeensis-infected
169 t that dogs serve as a reservoir of human E. canis infection and that R. sanguineus, which occasional
176 rucella abortus, Brucella suis, and Brucella canis) is problematic for many clinical laboratories tha
177 uantitatively (P < 0.01) among strains of M. canis isolated from canine brain tissue or mucosal surfa
179 and attempted emm typing of 5 Streptococcus canis isolates from a recent population-based surveillan
182 sgalactiae subsp. equisimilis isolates, 4 S. canis isolates) to represent each emm type identified, i
191 wolves Canis lupus are known to kill coyotes Canis latrans, and coyotes, in turn, may kill foxes Vulp
192 mutation also causes melanism in the coyote, Canis latrans, and in Italian gray wolves, and hence our
193 s in cats and raises the possibility that H. canis, like H. hepaticus and H. bilis in mice, can cause
194 Ehrlichia and Cowdria spp.: p30 of Ehrlichia canis (< or =71.3%), p28 of E. chaffeensis (< or =68.3%)
195 me from regions outside the natural range of Canis lupus (the dog's wild ancestor) and where dogs wer
196 For example, in North America, grey wolves Canis lupus are known to kill coyotes Canis latrans, and
197 o primary species studied, the domestic dog (Canis lupus familiaris) and the Tasmanian devil (Sarcoph
200 in prey composition and kill rate for wolves Canis lupus living on the Northern Range (NR) of Yellows
201 postcranial skeletal morphologies of wolves (Canis lupus) and coyotes (C. latrans) from Pleistocene-a
202 between dogs (Canis familiaris) and wolves (Canis lupus) has led some researchers to conclude that b
203 itment and population growth of grey wolves (Canis lupus) in Denali National Park and Preserve, Alask
204 rs of data from a long-term study of wolves (Canis lupus) in Yellowstone National Park, USA, to evalu
207 or 732 moose (Alces alces) killed by wolves (Canis lupus) over a 50-year period in Isle Royale Nation
209 (NCEs) of an active predator, the grey wolf (Canis lupus), by simultaneously tracking wolves and the
210 xplored multiple linkages among grey wolves (Canis lupus), elk (Cervus elaphus), berry-producing shru
212 jackals aligned more closely to gray wolves (Canis lupus), which is surprising given the absence of g
216 se serum antibody responses to whole-cell E. canis lysates and recombinant p28, gp140, and gp200 were
219 well explored, although recent studies of VY Canis Majoris have resulted in the identification of HCO
221 rsity of Ehrlichia chaffeensis and Ehrlichia canis may involve independent or differential expression
223 d isolates (P. dagmatis [n = 2], Pasteurella canis [n = 2], and N. canis [n = 1]) are discussed.
224 The 28-kDa E. chaffeensis and 30-kDa E. canis native proteins were recognized by 25 IFA-positive
225 ith exposure to canine parvovirus, Ehrlichia canis, Neospora caninum and perhaps rabies virus, but no
231 with DNA extracted from E. chaffeensis-, E. canis-, or E. phagocytophila-infected samples, confirmin
234 The overall amino acid sequence of the E. canis p120 is 30% homologous to that of E. chaffeensis p
235 lotting demonstrated that the recombinant E. canis p120 reacted with convalescent sera from dogs with
236 16 bp), the 14-repeat region (78%) of the E. canis P140 gene (1,620 bp), and a 2-repeat region from t
238 previously demonstrated that recombinant E. canis p28 and the 140- and 200-kDa glycoproteins gp140 a
240 4), Ehrlichia chaffeensis p28-OMP, Ehrlichia canis p30, and Ehrlichia ruminantium MAP1, and has been
243 eous cell line, or consistent patterns of M. canis polyvalent antigen distribution in canine meningoe
244 of the 16S rRNA genes from six additional E. canis-positive dog blood specimens and from three pooled
246 nfection, additional major immunoreactive E. canis proteins were identified, including the 28-, 47-,
247 eported the cloning of two immunoreactive E. canis proteins, P28 and P140, that were applicable for s
249 te was detected on the E. chaffeensis and E. canis recombinant proteins, including the two-repeat pol
252 d group size/composition in Ethiopian wolves Canis simensis in the Bale Mountains, Ethiopia, using fi
257 e invasive disease, the genome of Mycoplasma canis strain PG14(T) from a dog's throat was compared to
260 (Asian genotype), B. canis subsp. vogeli, B. canis subsp. canis, and B. canis subsp. rossi DNA in blo
261 (Asian genotype), B. canis subsp. vogeli, B. canis subsp. canis, and B. canis subsp. rossi DNA in can
262 subsp. vogeli, B. canis subsp. canis, and B. canis subsp. rossi DNA in blood samples from infected do
264 (Asian genotype), B. canis subsp. vogeli, B. canis subsp. rossi, and B. canis subsp. canis but not ma
265 entiate Babesia gibsoni (Asian genotype), B. canis subsp. vogeli, B. canis subsp. canis, and B. canis
266 discriminate B. gibsoni (Asian genotype), B. canis subsp. vogeli, B. canis subsp. canis, and B. canis
267 A genes from B. gibsoni (Asian genotype), B. canis subsp. vogeli, B. canis subsp. rossi, and B. canis
268 sent study we cloned a new immunoreactive E. canis surface protein gene of 1,170 bp, which encodes a
271 Da major outer membrane protein of Ehrlichia canis, the agent of canine ehrlichiosis, is the major an
272 ously culture isolated a strain of Ehrlichia canis, the causative agent of canine ehrlichiosis, from
275 oduce a draft genome and transcriptome of T. canis to support future biological and biotechnological
276 f these gene products in pathogenesis and E. canis transmission as well as in designing a rational va
279 ates and comparison with sequences of the S. canis type strain and other related streptococci of anim
280 e S. halichoeri type strain, 84.6% to the S. canis type strain, and 83.8% to the S. ictaluri type str
281 sis were examined for infection of Ehrlichia canis using PCR, multiplex real-time PCR, and DNA sequen
285 erric ion-binding protein (Fbp) of Ehrlichia canis was identified and its iron-binding capability was
286 notypic, and 16S rRNA analyses, Helicobacter canis was isolated from Bengal cats with and without chr
287 ing Campylobacter helveticus, and because H. canis was isolated from nondiarrheic cats, the causal ro
292 rucella abortus, Brucella suis, and Brucella canis were extracted and distributed to participating la
294 teins of Ehrlichia chaffeensis and Ehrlichia canis were identified which restored DsbA activity in co
297 own genes, and secA in the omp cluster in E. canis were transcriptionally active in the monocyte cult
299 e 30-kDa major outer membrane proteins of E. canis will greatly facilitate understanding pathogenesis
300 We presented a small shark species, Mustelus canis, with carefully timed and measured odor pulses dir
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