ライフサイエンスコーパス: Cinchona alkaloid

1 model involves nucleophilic catalysis by the cinchona alkaloid.

2 echanistic studies of reactions catalyzed by cinchona alkaloids.

3 insight into the conformational behavior of cinchona alkaloids.

4 laced from the surface by any of those other cinchona alkaloids.

5 gs (X-ray) were obtained via modification of Cinchona alkaloids.

6 ities comparable with those reported for the Cinchona alkaloid ammonium salts derivatives (83-96% ee)

7 The zwitterionic adduct between a cinchona alkaloid and ketone is adsorbed on Pt through t

8 Cinchona alkaloids and their derivatives are widely used

9 mperature adsorption of four closely related cinchona alkaloids and three reference quinoline-based c

10 ia include glycoprotein IIb/IIIa inhibitors, cinchona alkaloids, antibiotics, anticonvulsants, and he

11 In particular, sulfonamide derivatives of cinchona alkaloids are highly enantioselective desymmetr

12 ide, using a catalytic amount of a silylated cinchona alkaloid as a source of chirality.

13 rt the discovery of novel N,N'-disubstituted cinchona alkaloids as efficient phase-transfer catalysts

14 In comparison to traditional cinchona-alkaloid-based phase-transfer catalysts, these

15 discovery that, upon proper modification, a cinchona alkaloid bearing a thiourea functionality at 6'

16 is demonstrated for noncovalent complexes of cinchona alkaloid carbamate chiral selectors with N-dini

17 ogen bonding transition state (TS) model for cinchona alkaloid catalysis that we recently showed to b

18 The cinchona alkaloid catalyst benzoylquinine (BQ) mediates

19 and hydroperoxides and an easily accessible cinchona alkaloid catalyst, this novel reaction will ope

20 The reaction requires 10 mol % of the cinchona alkaloid catalyst, which serves as a general ba

21 reported by MacMillan, which uses a modified cinchona alkaloid catalyst.

22 oles with imines catalyzed by a bifunctional cinchona alkaloid catalyst.

23 C-9 arylated cinchona alkaloid catalysts have been found to be consid

24 ic anhydrides (AMMA) catalyzed by a class of cinchona alkaloid catalysts involves an oxyanion hole co

25 Predicted enantioselectivities of three cinchona alkaloid catalysts, namely DHQD-PHN, DHQD-MEQ,

26 n of the reactivity of acid chlorides, using cinchona alkaloid catalysts, results in chiral alpha,bet

27 Wynberg's report from 1977 that natural cinchona alkaloids catalyze the asymmetric conjugate add

28 First, our kinetic studies indicate that the cinchona alkaloid-catalyzed alcoholysis proceeds by a ge

29 dioxolanediones was realized via a modified cinchona alkaloid-catalyzed alcoholytic opening of the d

30 antioenriched dihydropyrimidone core was the Cinchona alkaloid-catalyzed Mannich reaction of beta-ket

31 The highly enantioselective cinchona alkaloid-catalyzed Mannich reaction of dicarbon

32 Cinchona alkaloid-catalyzed reaction of ethyl glyoxylate

33 kyl-9-BBN derivatives in the presence of the Cinchona alkaloid, cinchonidine, and base.

34 performance achieved by the use of a proline cinchona alkaloid conjugate designed in a de novo fashio

35 imal catalytic system was determined to be a cinchona alkaloid derivative (TMS-quinine or Me-quinidin

36 conformation studies with a designed, rigid cinchona alkaloid derivative as a probe.

37 The reaction is simply catalyzed by cinchona alkaloid derivatives affording the final alkyla

38 alcohol dichlorination catalyzed by dimeric cinchona alkaloid derivatives and employing aryl iododic

39 e, commercially available acid halides using cinchona alkaloid derivatives as catalysts and polychlor

40 Chiral cinchona alkaloid derivatives work best when paired with

41 The reactions herein are catalyzed by cinchona alkaloid derivatives, with the best performance

42 self-assembled in situ from amino acids and cinchona alkaloid derivatives.

43 of Lewis acids were screened in tandem with cinchona alkaloid derivatives; surprisingly, trans-(Ph(3

44 The Cinchona alkaloid derived chiral ammonium salt developed

45 ic induction in aldol reactions catalyzed by cinchona alkaloid-derived amines, and chiral vicinal dia

46 t matching effect between the chirality of a cinchona alkaloid-derived aminophosphine ligand for the

47 ed heterocycles can also be prepared using a Cinchona alkaloid-derived bifunctional organocatalyst fo

48 Furthermore, the active conformer of the cinchona alkaloid-derived catalyst DHQD-PHN was clarifie

49 terization of the active conformation of the cinchona alkaloid-derived catalyst for a desymmetrizatio

50 greater than that of a widely used thiourea cinchona alkaloid-derived catalyst.

51 A series of Cinchona alkaloid-derived dimers were obtained in high y

52 Cinchona alkaloid-derived organocatalysts as Bronsted ba

53 ines and enones under the catalysis of a new cinchona alkaloid-derived phase-transfer catalyst.

54 s reaction, disclosed by List et al. using a cinchona alkaloid-derived primary amine (cinchona amine)

55 Using cinchona alkaloid-derived primary amines as catalysts an

56 -fluorination of cyclic ketones catalyzed by cinchona alkaloid-derived primary amines is determined w

57 th phenylglyoxal hydrates were realized with cinchona alkaloid-derived thiourea catalysts.

58 The cinchona alkaloid-derived urea-catalyzed asymmetric conj

59 A cinchona-alkaloid-derived chiral primary-amine-catalyzed

60 es have been enantioselectively catalyzed by Cinchona alkaloids functionalized with a hydrogen bond d

61 The 9-amino(9-deoxy)epi cinchona alkaloids have expanded the synthetic potential

62 f solvent-induced conformational behavior of cinchona alkaloids in their reactivity.

63 modification the conformational behavior of cinchona alkaloids in various solvents can be convenient

64 The series of Cinchona alkaloids includes known C6' (thio)urea and sul

65 Reaction of dimethylsulfonium methylide with Cinchona alkaloid ketones proceeds with complete diaster

66 vities of reductions of activated ketones on cinchona alkaloid modified platinum is proposed and is s

67 ration of supercoiled plasmid topoisomers on cinchona-alkaloid modified silica-based stationary phase

68 The first cinchona-alkaloid-organocatalyzed enantioselective synth

69 alysis via a complex of silver acetate and a cinchona alkaloid, particularly hydroquinine, with compl

70 and quaternary ammonium bromide derived from cinchona alkaloids, provided nonracemic allene derivativ

71 We also demonstrate that the cinchona alkaloids quinidine and quinine give rise to pr

72 onformational interconversion barrier of the cinchona alkaloid scaffold.

73 lfa-Michael addition reaction catalyzed by a cinchona alkaloid-squaramide bifunctional organocatalyst

74 sembled from both enantiomers of proline and cinchona alkaloid thiourea derivatives.

75 Os) that are self-assembled from proline and cinchona alkaloid thioureas (such as a quinidine-derived

76 Bifunctional Cinchona alkaloid thioureas efficiently catalyze asymmet

77 nitroolefins in the presence of 1-6 mol % of cinchona alkaloid urea derivatives, and provided access

78 nding model, which works for cinchonidine or cinchona alkaloid-urea catalyzed sulfa-Michael addition

79 his dynamic kinetic resolution, the modified cinchona alkaloid was found to serve dual catalytic role

80 The reactions are catalyzed by a modified cinchona alkaloid, which can function as a bifunctional,