ライフサイエンスコーパス: Citrobacter

1 almonella clade (which includes Shigella and Citrobacter).

2 t was distinct from, Citrobacter farmeri and Citrobacter amalonaticus.

3 rs of the genera Vibrio , Enterobacter , and Citrobacter and by Bacillus stratosphericus was confirme

4 Propionibacterineae, Citrobacter, and Anaerococcus were the taxa found only i

5 Pseudomonas, Serratia, Hafnia, Enterobacter, Citrobacter, and Lactobacillus.

6 ignificantly inhibited autophagic killing of Citrobacter, attesting to the functional importance of t

7 (CYP176A1) is a bacterial P450 isolated from Citrobacter braakii that catalyzes the hydroxylation of

8 s of C. rodentium (named colonization factor Citrobacter, CFC).

9 Interestingly, Citrobacter colonization and clearance were unaffected i

10 nts and established that mouse mortality and Citrobacter colonization were reduced in mice infected w

11 more resistant to intestinal colonization by Citrobacter, developed lower levels of serum Citrobacter

12 ther strains of Salmonella as well as within Citrobacter, Erwinia, Escherichia, Photorhabdus, and Yer

13 ed most closely with, but was distinct from, Citrobacter farmeri and Citrobacter amalonaticus.

14 sinia intermedia, Kluyvera cryocrescens, and Citrobacter farmeri but identification scores were low a

15 studies on infant rats have documented many Citrobacter-filled macrophages within the ventricles and

16 bilis (4.0%), Klebsiella oxytoca (2.7%), and Citrobacter freundii (2.0%).

17 , Pseudomonas aeruginosa (40% identity), and Citrobacter freundii (38% identity).

18 ll-free supernatants from Proteus mirabilis, Citrobacter freundii and Enterobacter agglomerans [cyclo

19 detected in carbapenem-resistant isolates of Citrobacter freundii and Klebsiella oxytoca recovered fr

20 yme B12-dependent glycerol dehydratases from Citrobacter freundii and Klebsiella pneumoniae.

21 alyze transcription from the tpl promoter of Citrobacter freundii ATCC 29063 (C. braakii).

22 Citrobacter rodentium (formerly Citrobacter freundii biotype 4280 and Citrobacter genomo

23 Citrobacter rodentium (formally Citrobacter freundii biotype 4280) is a highly infectiou

24 We have previously shown that the Citrobacter freundii BMC associated with 1,2-propanediol

25 Neither the class C Citrobacter freundii CMY-2 AmpC beta-lactamase nor the c

26 The tpl gene of Citrobacter freundii encodes an enzyme that catalyzes th

27 e (WT) forms, such as the E. cloacae P99 and Citrobacter freundii enzymes, the ES GC1 beta-lactamase

28 iae, Klebsiella oxytoca, Citrobacter koseri, Citrobacter freundii group, Enterobacter spp., and Serra

29 rosine with tyrosine phenol-lyase (TPL) from Citrobacter freundii have been examined.

30 similar species such as Escherichia coli and Citrobacter freundii in real-time PCR assays.

31 Tyrosine phenol-lyase (TPL) from Citrobacter freundii is a pyridoxal 5'-phosphate (PLP)-d

32 Tyrosine phenol-lyase (TPL) from Citrobacter freundii is activated about 30-fold by monov

33 Tyrosine phenol-lyase (TPL) from Citrobacter freundii is dependent on monovalent cations,

34 lle and propanediol utilization enzymes from Citrobacter freundii is fully functional when cloned in

35 lococcus aureus, Pseudomonas aeruginosa, and Citrobacter freundii to ensure the species specificity o

36 ophan indole-lyase and to wild type and Y71F Citrobacter freundii tyrosine phenol-lyase was investiga

37 he molecular interactions between AmpR (from Citrobacter freundii), its DNA operator, and repressor U

38 tatively for Gram-negative Escherichia coli, Citrobacter freundii, and Enterobacter aerogenes, as wel

39 with colonization of the intestinal tract by Citrobacter freundii, Clostridium species, Enterobacter

40 c inhibition was also observed in strains of Citrobacter freundii, Klebsiella pneumoniae, Enterobacte

41 ve selectivity of these ligands for E. coli, Citrobacter freundii, Staphylococcus epidermidis were 10

42 lococcus aureus, Pseudomonas aeruginosa, and Citrobacter freundii, to ensure the species-specificity

43 five enterobacteria (Salmonella typhimurium, Citrobacter freundii, Yersinia enterocolitica, Serratia

44 robacter aerogenes, Morganella morganii, and Citrobacter freundii.

45 using primers specific for the ampC gene of Citrobacter freundii.

46 lass C enzymes from Enterobacter cloacae and Citrobacter freundii.

47 e, Escherichia coli, Klebsiella oxytoca, and Citrobacter freundii.

48 Additional strains of Citrobacter genomospecies 10 and Citrobacter genomospeci

49 strains of Citrobacter genomospecies 10 and Citrobacter genomospecies 11 were identified, allowing t

50 rmerly Citrobacter freundii biotype 4280 and Citrobacter genomospecies 9) was described on the basis

51 lowing these species to be formally named as Citrobacter gillenii sp. nov. and Citrobacter murliniae

52 species and two unnamed genomospecies within Citrobacter has enlarged the genus to 11 species.

53 infection, and had significantly attenuated Citrobacter-induced colitis.

54 To directly test whether RELMalpha promoted Citrobacter-induced intestinal inflammation via IL-17A,

55 Citrobacter-infected RELMalpha(-/-) mice exhibited reduc

56 RELMalpha treatment of Citrobacter-infected WT mice exacerbated intestinal infl

57 s previously inaccessible information on how Citrobacter infection and clearance reshapes the gut mic

58 e stimulatory effects of RELMalpha following Citrobacter infection were pathologic rather than host-p

59 significantly worsens the in vivo course of Citrobacter infection.

60 ia coli strain UTI89 and by enteric bacteria Citrobacter koseri and Salmonella enterica serovar typhi

61 S rDNA sequence was 97.8% similar to that of Citrobacter koseri but 97.0% similar to that of Enteroba

62 Gut-associated Citrobacter koseri genomes harbored 47 polymorphic sites

63 Citrobacter koseri is a Gram-negative bacterium that can

64 A unique feature of Citrobacter koseri is the extremely high propensity to i

65 These lesions were caused by Citrobacter koseri septicaemia, identified by transfonta

66 richia coli, Salmonella typhimurium LT2, and Citrobacter koseri were able to cross-seed in vitro.

67 , Klebsiella pneumoniae, Klebsiella oxytoca, Citrobacter koseri, Citrobacter freundii group, Enteroba

68 terization of a novel bacterial homolog from Citrobacter koseri, CLC-ck2, has yielded surprising disc

69 te Nus factor regulation of one such gene in Citrobacter koseri.

70 arithmic growth of Escherichia coli K1/r and Citrobacter koseri.

71 nine species, including the first isolate of Citrobacter koserii and Morganella morganii known to har

72 the coinfected mice was correlated with high Citrobacter loads in the gut, translocation of the bacte

73 The genera Citrobacter (log2 fold change -3.41, P=.03), Oscillospir

74 losely related genomes, such as S.bongori or Citrobacter, may help in this regard.

75 y named as Citrobacter gillenii sp. nov. and Citrobacter murliniae sp. nov., respectively.

76 logous genes in Escherichia, Salmonella, and Citrobacter, or E. coli, E. fergusonii, and E. albertii.

77 usly unidentified TonB homologs in Shigella, Citrobacter, Proteus, and Kluyvera species.

78 In response to Citrobacter, RELMalpha expression was induced in intesti

79 (EPEC), enterohemorrhagic E. coli (EHEC) and Citrobacter rodentium (CR) infections, are dependent on

80 Citrobacter rodentium (CR) promotes crypt hyperplasia an

81 Utilizing the Citrobacter rodentium (CR)-induced transmissible murine

82 an infection model, using the mouse pathogen Citrobacter rodentium (CR).

83 Citrobacter rodentium (formally Citrobacter freundii bio

84 a coli (EPEC)-mediated disease in humans and Citrobacter rodentium (formerly C. freundii biotype 4280

85 Citrobacter rodentium (formerly Citrobacter freundii bio

86 cute colitis induced by the enteric pathogen Citrobacter rodentium Adoptive transfer of macrophage-ri

87 killing of the extracellular enteropathogen Citrobacter rodentium after phagocytosis.

88 fense against acute bacterial infection with Citrobacter rodentium and Clostridium difficile.

89 Citrobacter rodentium and Escherichia coli O157 triggere

90 P3 activators LPS and ATP, Escherichia coli, Citrobacter rodentium and transfection of LPS, AIM2 acti

91 erichia coli, enterohemorrhagic E. coli, and Citrobacter rodentium are classified as attaching and ef

92 erichia coli, enterohemorrhagic E. coli, and Citrobacter rodentium are classified as attaching and ef

93 In this study, we employed Citrobacter rodentium as a physiologic model of pathogen

94 98 in IECs (hCD98 Tg mice) and infected with Citrobacter rodentium as an in vivo model.

95 The attaching and effacing mouse pathogen Citrobacter rodentium associates intimately with the int

96 Citrobacter rodentium causes a similar colitis in mice a

97 Citrobacter rodentium causes an attaching and effacing i

98 Citrobacter rodentium causes epithelial hyperplasia and

99 Dextran sodium sulfate (DSS) and Citrobacter rodentium colitis (CC) was induced in adult

100 Citrobacter rodentium colonizes the mouse colon in a sim

101 es after exposure to the intestinal pathogen Citrobacter rodentium Correspondingly, AQP3(-/-) mice sh

102 enteropathogenic Escherichia coli (EPEC) and Citrobacter rodentium during mammalian infections.

103 Lymphocyte inhibitory factor A (lifA) in Citrobacter rodentium encodes the large toxin lymphostat

104 also required for clearance of the bacterium Citrobacter rodentium from the gastrointestinal tract.

105 In mice, susceptibility to Citrobacter rodentium has been shown to be dependent on

106 the control of mouse colonic infection with Citrobacter rodentium in the presence of T cells.

107 onses to the attaching and effacing pathogen Citrobacter rodentium in these.

108 ry response to the colitis-inducing pathogen Citrobacter rodentium in vitro by inhibiting NF-kappaB a

109 n of the TLR7 agonist R848 or infection with Citrobacter rodentium in vivo.

110 activated by the colitis-inducing bacterium Citrobacter rodentium increased NO without affecting iNO

111 ride (LPS) and infection with mouse pathogen Citrobacter rodentium induce translocation of the nuclea

112 We found that the enteric pathogen Citrobacter rodentium induced sequential waves of IL-22-

113 Citrobacter rodentium induces transmissible murine colon

114 Citrobacter rodentium induces transmissible murine colon

115 milarly opposing phenotypes were observed in Citrobacter rodentium infection and allergic asthma.

116 22 receptor IL-22RA1 protects against lethal Citrobacter rodentium infection and chemical-induced col

117 sease, whereas expansion of these cells upon Citrobacter rodentium infection exacerbated pathology.

118 lsion, caused by a deficit in ILC2s, whereas Citrobacter rodentium infection is cleared efficiently.

119 Citrobacter rodentium infection of mice induces cell-med

120 ization following microbiome disruption with Citrobacter rodentium infection or antibiotic treatment,

121 nt mice are less able to eradicate a mucosal Citrobacter rodentium infection than wild-type C57BL/6 m

122 The pathogenesis of a Citrobacter rodentium infection was evaluated in mice fe

123 ency increased morbidity and mortality after Citrobacter rodentium infection with decreased secretion

124 During intestinal Citrobacter rodentium infection, a mouse model for enter

125 provides that link for the investigation of Citrobacter rodentium infection, a mouse model for enter

126 testinal epithelial cells after T. gondii or Citrobacter rodentium infection, but also maintained the

127 KKbeta(DeltaIEC) mice efficiently controlled Citrobacter rodentium infection, IKKalpha(DeltaIEC) mice

128 Using mouse model of Citrobacter rodentium infection, we investigated the rol

129 Ahr-deficient mice succumbed to Citrobacter rodentium infection, whereas ectopic express

130 nate inflammatory RelA/NF-kappaB response to Citrobacter rodentium infection, while Nfkb2(-/-) mice s

131 duced by dextran sodium sulfate treatment or Citrobacter rodentium infection.

132 ole of epithelial derived ILK in response to Citrobacter rodentium infection.

133 ed responses capable of protecting mice from Citrobacter rodentium infection.

134 tivation during both Helicobacter pylori and Citrobacter rodentium infection.

135 cus-degrading bacteria and susceptibility to Citrobacter rodentium infection.

136 critical inducers of the innate response to Citrobacter rodentium infection.

137 infection, repeated exposure to ketamine and Citrobacter rodentium infection.

138 conferred enhanced mucosal immunity against Citrobacter rodentium infection.

139 cells (DCs) and coexpressed with IL-23 after Citrobacter rodentium infection.

140 ons that T-helper cell, type 17 responses in Citrobacter rodentium infections are driven by concomita

141 herpes simplex virus, Toxoplasma gondii, and Citrobacter rodentium infections.

142 Infection with Citrobacter rodentium initially was controlled by ILC3,

143 Citrobacter rodentium is a natural mouse pathogen relate

144 Infection of mice with Citrobacter rodentium is a robust model to study bacteri

145 Citrobacter rodentium is an attaching and effacing mouse

146 Citrobacter rodentium is an enteric bacterial pathogen o

147 Citrobacter rodentium is an enteric pathogen which attac

148 Infection with the bacterium Citrobacter rodentium is known to increase epithelial ce

149 Citrobacter rodentium is the causative agent of transmis

150 Citrobacter rodentium is the causative agent of transmis

151 Citrobacter rodentium is the rodent equivalent of entero

152 Citrobacter rodentium is used as an in vivo model system

153 The Citrobacter rodentium model mimics the pathogenesis of i

154 in a CD4-specific knockout of NLRX1 within a Citrobacter rodentium model of colitis.

155 nvestigated the role of these enzymes in the Citrobacter rodentium model of colitis.

156 hage activation and disease phenotype in the Citrobacter rodentium model of murine infectious colitis

157 that in both the dextran sodium sulfate and Citrobacter rodentium models of colitis, significantly i

158 (EHEC), enteropathogenic E. coli (EPEC), and Citrobacter rodentium Moreover, Salmonella enterica stra

159 he involvement of Map in diarrhoea using the Citrobacter rodentium mouse model of EPEC.

160 ing infection by the murine enteric pathogen Citrobacter rodentium of the family Enterobacteriacea.

161 ute colitis was induced by administration of Citrobacter rodentium or dextran sulfate sodium (DSS) to

162 macrophages infected with Escherichia coli, Citrobacter rodentium or Vibrio cholerae.

163 with EPEC, using the mouse-specific pathogen Citrobacter rodentium Our murine infant model is similar

164 infection with Anaplasma phagocytophilum and Citrobacter rodentium respectively, were used.

165 mice with the intestinal bacterial pathogen Citrobacter rodentium results in colonic mucosal hyperpl

166 We also identified an lpf gene cluster in Citrobacter rodentium strain ICC168 (lpf(cr)).

167 We characterized Citrobacter rodentium strains bearing deletions in indiv

168 ies have found the murine bacterial pathogen Citrobacter rodentium to provide a robust, relevant in-v

169 Citrobacter rodentium uses a type III secretion system (

170 Citrobacter rodentium uses virulence factors similar to

171 Citrobacter rodentium was used as a Th17-inducing infect

172 Citrobacter rodentium was used to model human Escherichi

173 artonella spp., Lawsonia intracellularis and Citrobacter rodentium) can induce cellular proliferation

174 e against an epithelium-associated pathogen (Citrobacter rodentium).

175 In mice infected with Citrobacter rodentium, a model for enteropathogenic Esch

176 at germ-free animals are unable to eradicate Citrobacter rodentium, a model for human infections with

177 reover, mice lacking TACI were able to clear Citrobacter rodentium, a model pathogen for severe human

178 C, we constructed an Stx-producing strain of Citrobacter rodentium, a murine AE pathogen that otherwi

179 s derived from these mice were infected with Citrobacter rodentium, a murine attaching and effacing p

180 Using Citrobacter rodentium, a murine model of attaching and e

181 Citrobacter rodentium, a murine model pathogen for human

182 Citrobacter rodentium, a murine model pathogen that shar

183 C57BL/6 mice were orally gavaged with Citrobacter rodentium, a murine pathogen related to huma

184 Probiotics prevent disease induced by Citrobacter rodentium, a murine-specific enteric pathoge

185 Infection with Citrobacter rodentium, a natural mouse pathogen homologo

186 Citrobacter rodentium, a natural mouse pathogen, has rec

187 the murine gut microbiome to infection with Citrobacter rodentium, an attaching-and-effacing bacteri

188 e exhibited impaired intestinal clearance of Citrobacter rodentium, an enteric bacterium that models

189 The lifA/efa1 gene is also present in Citrobacter rodentium, an enteric pathogen that causes a

190 wnregulation of virulence gene expression in Citrobacter rodentium, an enteric pathogen that models h

191 ike toxin-producing E. coli, E. coli RDEC-1, Citrobacter rodentium, and an EPEC espB insertion mutant

192 hesins of enteropathogenic Escherichia coli, Citrobacter rodentium, and enterohemorrhagic E. coli (EH

193 tary intervention, mice were challenged with Citrobacter rodentium, and pathological responses were a

194 usceptible strain of the pathogenic bacteria Citrobacter rodentium, and we propose a general approach

195 e surrogate murine infection model for EHEC, Citrobacter rodentium, are all examples of microorganism

196 m the mouse attaching and effacing pathogen, Citrobacter rodentium, as a potential drug target.

197 We demonstrate that after infection with Citrobacter rodentium, CD4(+) LTi cells were a dominant

198 after infection with the intestinal pathogen Citrobacter rodentium, leading to impaired survival.

199 resistance against a murine enteropathogen, Citrobacter rodentium, leading to the death of the anima

200 in the context of intestinal infection with Citrobacter rodentium, resulting in preserved innate imm

201 ANR homologs of Vibrio cholerae, Citrobacter rodentium, Salmonella enterica and ETEC were

202 egative bacteria including Escherichia coli, Citrobacter rodentium, Salmonella typhimurium, and Shige

203 EPEC), as well as the related mouse pathogen Citrobacter rodentium, utilize a type III secretion syst

204 rine infection model with one such pathogen, Citrobacter rodentium, was used to elucidate the importa

205 ice with the attaching and effacing bacteria Citrobacter rodentium, we defined the mechanisms and con

206 Using a mouse A/E pathogen, Citrobacter rodentium, we show that interleukin-22 (IL-2

207 d inflammation by the enteric mouse pathogen Citrobacter rodentium, which causes disease similar to t

208 d the murine attaching and effacing pathogen Citrobacter rodentium, which colonizes primarily the sur

209 nse generated to the extracellular bacterium Citrobacter rodentium, which induces a mixed Th1 and Th1

210 activity against the murine enteric pathogen Citrobacter rodentium, which like the related clinically

211 testinal epithelium with the rodent pathogen Citrobacter rodentium, which models human infections wit

212 epithelial barrier function in vitro and on Citrobacter rodentium-induced colitis in mice.

213 in IL-22-dependent colitis was confirmed in Citrobacter rodentium-induced disease.

214 ucosa-associated microbiota, and exacerbates Citrobacter rodentium-induced inflammation, effects that

215 Utilizing the Citrobacter rodentium-induced transmissible murine colon

216 long with the anti-swarming activity against Citrobacter rodentium.

217 tion of mice by the EPEC-like mouse pathogen Citrobacter rodentium.

218 istration of dextran sulfate sodium (DSS) or Citrobacter rodentium.

219 ppled responses to intestinal infection with Citrobacter rodentium.

220 nce of the attaching/effacing mouse pathogen Citrobacter rodentium.

221 ir selective depletion during infection with Citrobacter rodentium.

222 itical for the clearance of the A/E pathogen Citrobacter rodentium.

223 ty against an intestinal bacterial pathogen, Citrobacter rodentium.

224 unity to the attaching-and-effacing pathogen Citrobacter rodentium.

225 zene sulfonic-acid (TNBS); or infection with Citrobacter rodentium.

226 ease induced by the model bacterial pathogen Citrobacter rodentium.

227 h the enteric pathogens Escherichia coli and Citrobacter rodentium.

228 uced colonization levels of the gut pathogen Citrobacter rodentium.

229 and ILFs in the colon during infection with Citrobacter rodentium.

230 nged orally with the enteric murine pathogen Citrobacter rodentium.

231 hanced resistance to the intestinal pathogen Citrobacter rodentium.

232 onization of the mouse colon by the bacteria Citrobacter rodentium.

233 the gram-negative enteric bacterial pathogen Citrobacter rodentium.

234 on with the gram-negative bacterial pathogen Citrobacter rodentium.

235 more aggressive infectious colitis caused by Citrobacter rodentium.

236 ost protection against a bacterial pathogen, Citrobacter rodentium.

237 ted in the A/E-lesion-forming mouse pathogen Citrobacter rodentium.

238 enteropathogenic Escherichia coli (EPEC) and Citrobacter rodentium.

239 and lethal colitis by the mucosal pathogen, Citrobacter rodentium.

240 infection with the EPEC-like mouse pathogen Citrobacter rodentium.

241 impaired gut colonization resistance against Citrobacter rodentium.

242 onse to the attaching and effacing bacterium Citrobacter rodentium.

243 mpaired clearance of the intestinal pathogen Citrobacter rodentium.

244 of Runx3 in ILCs exacerbated infection with Citrobacter rodentium.

245 with LPS or infected with the enteropathogen Citrobacter rodentium.

246 ssential for the protective immunity against Citrobacter rodentium.

247 specially in the colon during infection with Citrobacter rodentium.

248 Salmonella enterica serovar Typhimurium and Citrobacter rodentium.

249 improves host tolerance of the mild pathogen Citrobacter rodentium.

250 evere colitis and death after infection with Citrobacter rodentium.

251 PEC and EHEC) and the natural mouse pathogen Citrobacter rodentium.

252 Citrobacter sedlakii was isolated from blood and cerebro

253 A nonpathogenic strain of Citrobacter sedlakii which expresses the Escherichia col

254 eruginosa, using a bioflocculant produced by Citrobacter sp.

255 as a substrate to grow a bioflocculant using Citrobacter sp.

256 A Citrobacter sp. accumulates uranyl ion (UO2(2+)) as crys

257 omass could be reutilized as a substrate for Citrobacter sp. AzoR-1 cultivation and bioflocculant pro

258 Bioflocculant synthesis by Citrobacter sp. AzoR-1 using microalga as a substrate, i

259 pediatric patient due to the newly described Citrobacter species C. farmeri is described.

260 d DNA-DNA hybridization data and is the only Citrobacter species known to possess virulence factors h

261 In addition, opportunistic infections with Citrobacter species or Klebsiella species occurred only

262 Only Citrobacter species were sensitive to all antibiotics te

263 istance against Clostridium, Salmonella, and Citrobacter species, researchers are now exploring mecha

264 14 strains (10%) were misidentified as other Citrobacter species.

265 two strains (2%) were misidentified as other Citrobacter species.

266 Citrobacter, developed lower levels of serum Citrobacter-specific IgM and IgG antibodies following or

267 Surviving mice develop robust Citrobacter-specific serum IgM responses during acute in

268 s growing Enterobacter spp, Serratia spp, or Citrobacter spp were evaluated using the cefotetan-boron

269 cter spp. (13), Enterobacter aerogenes (11), Citrobacter spp. (10), Pseudomonas spp. (non P. aerugino

270 the chromosomal enzymes of Enterobacter and Citrobacter spp. and also mediate resistance to extended

271 Citrobacter spp. cause neonatal meningitis but are uniqu

272 The pathogenesis of Citrobacter spp. causing meningitis and brain abscess is

273 an effort to understand the pathogenesis of Citrobacter spp. causing meningitis, we have used the in

274 s spp., 100%; Acinetobacter spp., 98.4%; and Citrobacter spp., 100%.

275 , P. aeruginosa, and S. marcescens, 5/6 with Citrobacter spp., 13/14 with Enterobacter spp., 23/24 wi

276 solates of Enterobacter spp., Serratia spp., Citrobacter spp., and Pseudomonas aeruginosa were evalua

277 9 genus/species targets (Acinetobacter spp., Citrobacter spp., Enterobacter spp., Escherichia coli/Sh

278 lmonella spp., Shigella spp., Yersinia spp., Citrobacter spp., enterotoxigenic (ETEC) and enteroaggre

279 Modeling of Citrobacter strain abundance suggests differences in gro

280 The relative abundance of two Citrobacter strains sharing ~99% nucleotide identity cha

281 Complementing DeltanleH with NleH1 restored Citrobacter virulence and colonization to wild-type leve

282 Moreover, autophagy of Citrobacter was inhibited by treating macrophages with I