ライフサイエンスコーパス: Claisen rearrangement

1 ngle ambimodal transition state, and a retro-Claisen rearrangement.

2 ether 23 by Petasis olefination, followed by Claisen rearrangement.

3 ond cleavage and C1---C9 bond formation in a Claisen rearrangement.

4 a Chan-Lam-type allyloxylation followed by a Claisen rearrangement.

5 thways followed by either tautomerization or Claisen rearrangement.

6 eterocyclic carbene catalyzed variant of the Claisen rearrangement.

7 tive conformation to spontaneously undergo a Claisen rearrangement.

8 t was combined with an Ireland ester enolate Claisen rearrangement.

9 -catalyzed tandem Diels-Alder reaction/retro-Claisen rearrangement.

10 ain, and the other to prephenate by a facile Claisen rearrangement.

11 lic isomerizations, allylic alkylations, and Claisen rearrangements.

12 tive [2,3]-Wittig-oxy-Cope and isomerization-Claisen rearrangements.

13 cumulenes are more reactive toward 1,3-diaza-Claisen rearrangements.

14 diastereoselective examples of archetypical Claisen rearrangements.

15 roups, by a novel tandem double condensation/Claisen rearrangement, a gold(I)-catalyzed alkyne hydroa

16 For the thiono-Claisen rearrangement, a notable structure-reactivity re

17 In the competing Claisen rearrangement, a very large 18O isotope effect a

18 The tandem, sequential use of the Ireland-Claisen rearrangement also proved suitable for chirality

19 The latter, when heated, undergo a Claisen rearrangement and form gamma,delta-unsaturated a

20 y crossover observed between the Eschenmoser-Claisen rearrangement and the thio-Claisen rearrangement

21 er-accelerated catalytic carboalumination, a Claisen rearrangement, and a nucleophilic carbonyl addit

22 nclude a Ru-catalyzed [5+2] cycloaddition, a Claisen rearrangement, and a ring expansion to construct

23 anic reactions, namely Diels-Alder reaction, Claisen rearrangement, and Cope-type hydroamination.

24 ion, substrate-directed epoxidation, Ireland-Claisen rearrangement, and diastereotopic group selectiv

25 anion formation strategy for asymmetric thio-Claisen rearrangement are documented.

26 ction and chirality transfer through Ireland-Claisen rearrangement as key steps.

27 Using an aza-Claisen rearrangement as the key step, 7-prenylindole ha

28 activation parameters are consistent with a Claisen rearrangement as the rate-limiting step.

29 d, and together they enhance the rate of the Claisen rearrangement by a factor of 58 over the backgro

30 ic end product via the (SAM-dependent) retro-Claisen rearrangement catalysed by LepI.

31 This Ireland-Claisen rearrangement delivered approximate 1:1 mixtures

32 rearrangement sequence, wherein the Ireland Claisen rearrangement effects ring contraction to a stra

33 ction with styryl bromide via O-styrylation, Claisen rearrangement, ene reaction, and O-alkylation oc

34 d via two efficient through processes: (1) a Claisen rearrangement followed by a Ru(VIII)-catalyzed o

35 etone 16 has been prepared by using an oxaza-Claisen rearrangement, followed by nitrogen deprotection

36 mary of our most recent study using the thio-Claisen rearrangement for the synthesis of anti-beta-fun

37 d acid catalyzed enantioselective indole aza-Claisen rearrangement for the synthesis of chiral 3-amin

38 de, and diisopropylamine, via an ortho ester-Claisen rearrangement from a propargylic alcohol, or via

39 a link to the indole core is introduced by a Claisen rearrangement from the allylated phenol moiety o

40 Formal Claisen rearrangement gives alpha-benzoyloxyazo compound

41 s to allyl fumarates with subsequent Ireland-Claisen rearrangement has been accomplished yielding sub

42 lytic, enantioselective Meerwein-Eschenmoser Claisen rearrangement has been achieved.

43 The carbanion-accelerated Claisen rearrangement has been extended to include phosp

44 effects on the stereochemical outcome of the Claisen rearrangements have been examined.

45 other methods for catalytic enantioselective Claisen rearrangements have not provided a satisfactory

46 r Diels-Alder reaction, and the Cope and the Claisen rearrangements) have been characterized.

47 o the intramolecular delivery of ring E (via Claisen rearrangement, Heck-type cyclization, or radical

48 readily obtained using olefin isomerization-Claisen rearrangement (ICR) reactions to prepare the key

49 iversity available from olefin isomerization-Claisen rearrangement (ICR) reactions.

50 Benzothiazole formation and Claisen rearrangement involve the cleavage of S-S and C-

51 [Chemical reaction: see text] A Claisen rearrangement/iodolactamization sequence startin

52 Although the aromatic aza-Claisen rearrangement is a general strategy for accessin

53 The propargyl Claisen rearrangement is a known protocol to gain access

54 The Ireland-Claisen rearrangement is effectively utilized to establi

55 New insight into solvent effects for the Claisen rearrangement is presented herein, and a QM/MM a

56 chenmoser-Claisen rearrangement and the thio-Claisen rearrangement is proposed.

57 The Ireland-Claisen rearrangement is the central step in the synthes

58 atalysts have been designed for the aromatic Claisen rearrangement of a 1,1-dimethylallyl coumarin.

59 Metal-catalyzed, double Claisen rearrangement of a bis-allyloxyflavone has been

60 The catalytic asymmetric Claisen rearrangement of a Gosteli-type allyl vinyl ethe

61 the strategy is a tandem Claisen/Diels-Alder/Claisen rearrangement of a suitably substituted xanthone

62 Specifically, the unimolecular Claisen rearrangement of allyl p-nitrophenyl ether (ApNE

63 in highly enantioselective catalysts for the Claisen rearrangement of allyloxy- and propargyloxy-indo

64 zes on the highly diastereoselective Ireland-Claisen rearrangement of an acyclic alpha-branched allyl

65 by the chorismate mutase (CM) enzyme for the Claisen rearrangement of chorismate to prephenate has be

66 Solvent effects on the rate of the Claisen rearrangement of chorismate to prephenate have b

67 he transition state, were calculated for the Claisen rearrangement of chorismate to prephenate in six

68 key step of the first approach relies on the Claisen rearrangement of glucal 18 to provide ester 20a.

69 The N-heterocyclic carbene (NHC)-catalyzed Claisen rearrangement of hybrid Ireland-Coates structure

70 c ketone 33 was prepared by sequential Tebbe-Claisen rearrangement of lactones 29 and 30, which origi

71 ssentially constitutes a Pd(0)-catalyzed aza-Claisen rearrangement of N-allyl ynamides, which can als

72 ole-substituted guanidinium ions promote the Claisen rearrangement of O-allyl alpha-ketoesters and in

73 thetic sequence involving the use of Ireland-Claisen rearrangement of propargylic acetates to form th

74 Key steps include the O-allylation/Claisen rearrangement of spirolactone systems, which are

75 The Ireland-Claisen rearrangement of the bis-allylic esters occurred

76 -gamma-lactone derivatives using the thermal Claisen rearrangement of the corresponding 3-O- and 2-O-

77 onate 46, methylenation of 46 and subsequent Claisen rearrangement of the corresponding alkenyl-subst

78 tudies of the aldol condensation and Ireland-Claisen rearrangement of the resulting Et 3N-solvated en

79 The aromatic Claisen rearrangements of allyl p-R-phenyl ethers (R = C

80 ts were discovered as superior in catalyzing Claisen rearrangements of allyloxy- or proparyloxy-subst

81 The Claisen rearrangements of chorismate (CHOR) in water and

82 Highly enantioselective catalytic Claisen rearrangements of ester-substituted allyl vinyl

83 st energy pathway (cation-accelerated oxonia Claisen rearrangement) originates from the second most s

84 phosphorus-stabilized, carbanion-accelerated Claisen rearrangements proceed rapidly at room temperatu

85 The Ireland-Claisen rearrangement proceeds with high diastereoselect

86 A sequential allyl vinyl ether formation-Claisen rearrangement process catalyzed by a palladium(I

87 In the case of cyclodienes, the Ireland-Claisen rearrangement produced s-trans locked dienes whi

88 An initial Ireland-Claisen rearrangement produced the benzannulated enyne-a

89 allylic alkoxides gave products arising from Claisen rearrangement, providing access to keto-alkenes

90 An enantioselective alkoxylation/Claisen rearrangement reaction was achieved by a strateg

91 is stereochemically complementary to related Claisen rearrangement reactions--processes that typicall

92 d enantioselective variants of the venerable Claisen rearrangement remain relatively rare.

93 A one-pot difluorocyclopropenation/Ireland-Claisen rearrangement sequence applied to readily availa

94 assisted tandem oxyanionic 5-exo cyclization/Claisen rearrangement sequence.

95 significantly more reactive toward 1,3-diaza-Claisen rearrangements than isoquinuclidene 2.

96 logenation of a simple alkene, and a Johnson-Claisen rearrangement that generates a quaternary carbon

97 tion of cyclic carbonate 90 in tandem with a Claisen rearrangement that generates the octenalactone p

98 onyl shift was made when examining these aza-Claisen rearrangements thermally.

99 )-catalyzed olefin isomerization and in situ Claisen rearrangement to afford stereodefined beta-boryl

100 gent approach featuring (1) a double Ireland Claisen rearrangement to establish key core bonds with c

101 Both routes utilized an efficient aza-Claisen rearrangement to establish the absolute stereoch

102 ant allyl ethers were subjected to a thermal Claisen rearrangement to give the corresponding methyl 7

103 ic iridium(I) catalyst followed by a thermal Claisen rearrangement to provide the allylsilanes in exc

104 The key steps involve a Claisen rearrangement to set up a 4-substituted-3-methyl

105 was obtained by a similar strategy involving Claisen rearrangement to transfer an allyl group from th

106 erionic intermediates that undergo 1,3-diaza-Claisen rearrangements to afford highly substituted urea

107 addition transition state is followed by the Claisen rearrangement transition state.

108 Claisen rearrangement transition states are also highly

109 urface by shifting the cycloaddition and the Claisen rearrangement transition states in opposite dire

110 relative positions of the bis-pericyclic and Claisen rearrangement transition states may control peri

111 ported relying on a key efficient asymmetric Claisen rearrangement, triggered by electrophilic activa

112 This allylic alcohol is then utilized in a Claisen rearrangement under Johnson's conditions to intr

113 p, allylation of the 5-hydroxyl, followed by Claisen rearrangement under microwave conditions with co

114 e-tethered chromanone/coumarin scaffolds via Claisen rearrangement using a solid state melt reaction

115 2 decreases the reactivity toward 1,3-diaza-Claisen rearrangements, while the exodiastereomers 3b an

116 irst examples of asymmetric induction in the Claisen rearrangement with chiral, phosphorus, anion-sta

117 marked (20-fold) acceleration of the Ireland-Claisen rearrangement with evidence of autocatalysis.