ライフサイエンスコーパス: CoCl

1 in (S = 3/2) three-coordinate complex ((Tr)L)CoCl.

2 de complexes ((Ar)PDI)CoCl(2) and ((iPr)BPDI)CoCl(2) ((Ar)PDI = 2,6-(2,6-R(2)-C(6)H(3)N=CMe)(2)C(5)H(

3 S,S)-2,4-bis-diphenylphosphinopentane (BDPP)]CoCl(2) (0.05 equiv) and methylaluminoxane.

4 duced by hypoxia ( approximately 1% O(2)) or CoCl(2) (hypoxia mimic), similarly to that for TGF-beta-

5 n EC exposed to CoCl(2) , P. gingivalis, and CoCl(2) + P. gingivalis (p < 0.05).

6 sed to CoCl(2), P. gingivalis (MOI 100), and CoCl(2) + P. gingivalis was evaluated through hypoxia de

7 mononuclear cells incubation with NiSO(4) , CoCl(2) , and PdCl(2) increased frequencies of CD154 + C

8 IF-1alpha, and MMP-9 levels in EC exposed to CoCl(2) , P. gingivalis, and CoCl(2) + P. gingivalis (p

9 In CoCl(2) -injured retinas, blockade of endogenous extrace

10 receptor damage caused by a specific dose of CoCl(2) .

11 th and progenitor proliferation induced with CoCl(2) .

12 ut not in control slices that were bathed in CoCl(2) alone, nor in slices that were bathed with the n

13 )pyridine cobalt dihalide complexes ((Ar)PDI)CoCl(2) and ((iPr)BPDI)CoCl(2) ((Ar)PDI = 2,6-(2,6-R(2)-

14 ta showed that pharmacological HIF inducers, CoCl(2) and DFO, did not affect Ang2 expression.

15 and chemicals known to stabilise HIF-1alpha (CoCl(2) and DMOG) on bone formation.

16 Interestingly, both hypoxia mimetics (CoCl(2) and DMOG) partly restored hyperglycaemia inhibit

17 bit sorption capacities, Q = 1.33 mmol/g for CoCl(2) and Q = 0.66 mmol/g for Co(NO(3))(2), as inferre

18 identifies the rich category of polarons in CoCl(2) and their feasibility of precise control unprece

19 Both CoCl(2) and X/XO induced neurite outgrowth in PC12 cells

20 ce of cobalt(II)-salts like Co(ClO(4))(2) or CoCl(2) bind the second Co(II)-ion; further internal ele

21 A heat-driven catch-and-release strategy for CoCl(2) capture is described.

22 ith catalytic amounts of bidentate phosphine-CoCl(2) complexes {[P~P](CoCl(2))} and Me(3)Al in an atm

23 and DeltaS degrees = 85.0 J/K.mol for PS-L + CoCl(2) in 95% ethanol.

24 parameter changes due to the hypoxia mimetic CoCl(2) in the p53 mutated SKNBE2(c) human neuroblastoma

25 Sodium amalgam reduction of CoCl(2) in the presence of CNAr(Mes2) provides the salt

26 Metalation of ((Tr)L)Li with CoCl(2) in THF afforded a high-spin (S = 3/2) three-coor

27 RL/MpJ MDSPCs with dimethyloxalylglycine and CoCl(2) increased the expression of HIF-1alpha and targe

28 spin states and metallization in compressed CoCl(2) is investigated by combining diffraction, resist

29 Cultured retinal cells were treated with CoCl(2) or 2% O(2) to induce hypoxia.

30 In normal PASMCs, HIF-1alpha activation by CoCl(2) or desferrioxamine causes DRP1-mediated fission.

31 iffraction analysis of a single crystal of L.CoCl(2) revealed an ion-pair complex comprising a hexaco

32 In Ka13 cells, CoCl(2) stimulated expression of a luciferase reporter g

33 The device was used to enrich CoCl(2) treated MDA-MB 231 breast cancer cells from an u

34 an hepatoma cells and repressed threefold by CoCl(2) treatment in rabbit corneal stromal and epitheli

35 in normoxic condition in vitro, hypoxia and CoCl(2) treatment increased Epo secretion.

36 -1alpha translation was potently elevated by CoCl(2) treatment, as determined by de novo translation

37 nd the production of extracellular S1P after CoCl(2) treatment, whereas HIF-1alpha small interfering

38 ated in its translational upregulation after CoCl(2) treatment.

39 ot further induce translation in response to CoCl(2) treatment.

40 ep-a) was up-regulated upon both hypoxia and CoCl(2) treatments.

41 CoCl(2) upregulated Hsp27 in cultured retinal neurons.

42 Furthermore, CoCl(2) upregulated Hsp27 in the rat retina and protecte

43 del of retinal ischemia to determine whether CoCl(2) upregulates rHsp27 and protects the retina from

44 response to hypoxia and the hypoxia-mimetic CoCl(2) was similar to that observed in wild type (K1) c

45 e steady state generation of superoxide, and CoCl(2) was used as a representative transition metal re

46 CoCl(2) was used to test for Hsp27 expression after hypo

47 ha expression and translation in response to CoCl(2) were markedly elevated after HuR overexpression.

48 binding and release of cobalt(II) chloride (CoCl(2)) via a solvent polarity switch mechanism involvi

49 II) chloride (FeCl(2)), cobalt(II) chloride (CoCl(2)), copper(I) chloride (CuCl)] are effective catal

50 with ZnCl(2) (and to 74% by the addition of CoCl(2)).

51 bidentate phosphine-CoCl(2) complexes {[P~P](CoCl(2))} and Me(3)Al in an atmosphere of ethylene.

52 cells (MIO-M1) were treated with 100 microM CoCl(2), 1 microg/mL triamcinolone acetonide (TA), or bo

53 lutarate, and ascorbate and was inhibited by CoCl(2), 3,4-dihydroxybenzoate, and 3,4-dihydroxyphenyl

54 binding constants of K(LF) = 88.5 M(-1) for CoCl(2), 52.7 M(-1) for MnCl(2), and 49.7 M(-1) for NiCl

55 or embryos exposed to 10 mM cobalt chloride (CoCl(2), a chemical inducer of hypoxia-inducible factor

56 exposed to 1 mM glutamate in the presence of CoCl(2), a subset of spindle-shaped taste cells accumula

57 ol and DeltaS degrees = 56.0 J/K.mol for L + CoCl(2), and DeltaH degrees = 16.5 kJ/mol and DeltaS deg

58 with other oxidative stresses, including UV, CoCl(2), and H(2)O(2) treatments.

59 n when exposed to CdCl(2), ZnSO(4), NiCl(2), CoCl(2), CuCl(2), heat, UV-B and carbofuron showed incre

60 Normoxic inducers of HIF (CoCl(2), desferrioxamine, and l-mimosine) and 100 ng/ml

61 The complex, (dppp)CoCl(2), gives the best results (ratio of 1,2- to 1,4-ad

62 was established via applying hypoxia mimetic CoCl(2), iron chelator desferrioxamine, proteasome inhib

63 s, that can be simulated with treatment with CoCl(2), leads to an increase in glycolysis, and more da

64 sence of hypoxia-mimicking concentrations of CoCl(2), mitochondrial but not nuclear DNA damage is ind

65 a simulated ion mixture containing equimolar CoCl(2), MnCl(2), and NiCl(2), ICP-MS analyses served to

66 of flowering, and have enhanced tolerance to CoCl(2), molybdic acid, ZnSO(4), and MgCl(2).

67 tus in oral epithelial cells (EC) exposed to CoCl(2), P. gingivalis (MOI 100), and CoCl(2) + P. gingi

68 a mimetics such as deferoxamine mesylate and CoCl(2), regardless of their HIF-alpha protein expressio

69 manipulation of single polarons in monolayer CoCl(2), that are grown on HOPG substrate via molecular

70 In supplemented minimal media containing CoCl(2), the metabolically produced CoPPIX is directly i

71 k chorioallantoic membranes and treated with CoCl(2), to model hypoxia, demonstrate increased dissemi

72 By subjecting TE-tagged cells to CoCl(2), we found the TE integration provided the major

73 r glutamate (0.5 or 1 mM) in the presence of CoCl(2), which can pass into cells through the ligand-ga

74 iate stimulation by dioxin and repression by CoCl(2), which simulates hypoxia.

75 mTOR enhanced HIF-1 activation by hypoxia or CoCl(2), while expression of a rapamycin-resistant mTOR

76 e report an unprecedented microwave-assisted CoCl(2)-catalyzed acceptorless dehydrogenative coupling

77 veral HIF-1 binding sites were necessary for CoCl(2)-induced expression of the Hsp27 gene.

78 the effects of etoposide-induced DNA damage, CoCl(2)-induced hypoxia, and 5' cap inhibition with 4EGI

79 Here, we report that during CoCl(2)-induced hypoxic stress, HuR is significantly ove

80 eins were found to bind HIF-1alpha mRNA in a CoCl(2)-inducible manner as assessed by immunoprecipitat

81 Additionally, both CoCl(2)-mimicked hypoxia and suppression of endogenous S

82 tion of HTR-8 cell migration and invasion by CoCl(2)-mimicked hypoxia was through the SRC-3/AKT/mTOR

83 HIF-1alpha levels increased dramatically in CoCl(2)-treated cells, while HIF-1alpha mRNA levels were

84 is was also mimicked by exposure of cells to CoCl(2).

85 HeLa cells responding to the hypoxia mimetic CoCl(2).

86 gulate HIF-1alpha translation in response to CoCl(2).

87 d with hypoxia or the hypoxia mimetic agent, CoCl(2).

88 that was activated by addition of ZnCl(2) or CoCl(2).

89 ependent transcription induced by hypoxia or CoCl(2).

90 thway leading to HIF-1alpha stabilization by CoCl(2).

91 isms for ho-1 gene activation by hypoxia and CoCl(2).

92 etected with exposure of cells to 100 microM CoCl(2).

93 onolayer two-dimensional (2D) semiconductor, CoCl(2).

94 Ion chromatographic analysis of a mixed CoCl(2)/Co(NO(3))(2) solution revealed an increase in ch

95 A catalyst system comprising CoCl(2)/IAd.HBF(4) enables the Suzuki-Miyaura cross-coup

96 The system CoCl(2)/Pr(i)(3)P/(Me(3)Si)(2)S/THF assembles [Co(4)S(4)

97 isotope effect reveal the mechanism of this CoCl(2-)catalyzed reaction to be via ADC.

98 es shows that the structures containing the [CoCl 4] (2-) anion are contracted along the <101> vector

99 ing the [CoBr 4] (2-) anion for the smaller [CoCl 4] (2-) anion.

100 STEM/EDS analysis, we demonstrate that Li(2)CoCl(4) first reacts with one Li(+) following a displace

101 lammonium) chloride) changes the mobility of CoCl(4)(2-) by electrostatic stabilization, which tunes

102 ormation of anionic cobalt chloride complex (CoCl(4)(2-)), while maintaining nickel in the cationic f

103 similar anionic framework with pristine Li(2)CoCl(4), ensuring the topotactic insertion of Li(+) bala

104 bution function (PDF) analysis of Co(bba)(3)[CoCl(4)] [bba = N,N'-1,4-butylenebis(acetamide)], which

105 es from the high thermodynamic stability of [CoCl(4)](2-), which facilitates its outer-sphere coordin

106 [L.Co](2+) and a tetrachlorocobaltate anion [CoCl(4)](2-).

107 Excess-anion incorporation into Cs(3)CoCl(5)-type materials has not been previously reported,

108 These are the first examples of ternary Cs(3)CoCl(5)-type nitrides, and show that this (MN(4))NLa(3)

109 action is enabled by the formation of a Li(6)CoCl(8) intermediate, which shares a similar anionic fra

110 ough the formal cleavage and reassembly of C-COCl bonds, was developed and explored for a range of ac

111 These include a structure for Tp(t-Bu,Me)CoCl different from that previously reported.

112 tecting group followed by acylation with R(2)COCl introduced the second element of diversity.

113 The ubiquitary Co(I) complex CoCl(PPh3)3 was found to be a convenient catalyst for th

114 Complexes (R,R)-(salcy)CoCl, (R,R)-(salcy)CoBr, (R,R)-(salcy)CoOAc, and (R,R)-(

115 phosphine)iminium) with complex (R,R)-(salcy)CoCl, (R,R)-(salcy)CoBr, or (R,R)-(salcy)CoOBzF(5) resul

116 s then treated with Ac(2)O, BzCl, and PhCH(2)COCl to provide the corresponding meso diesters, 20-22.

117 Chemical reduction of ((Tr)L)CoCl with potassium graphite yielded the high-spin (S =