1 manipulated by Mycobacteria, Leishmania, and
Coxiella.
2 Coxiella actively regulates multiple events during infec
3 es were found to associate with ribosomes of
Coxiella and E. coli.
4 ystems found in the pathogens Legionella and
Coxiella and the conjugative apparatus of IncI plasmids.
5 teria of the genera Brucella, Rickettsia and
Coxiella,
and corona-, calici- and lyssaviruses and viru
6 Legionella and
Coxiella are intracellular pathogens that use the virule
7 Inhalation of low doses of
Coxiella bacteria can result in infection of the host al
8 Recombinant
Coxiella BCP (rBCP) was generated, and its DNA binding w
9 Taken as a whole, the results show that
Coxiella BCP binds DNA and likely serves to detoxify end
10 Functional expression of
Coxiella bcp was demonstrated by trans-complementation o
11 Coxiella BCP was initially identified as a potential DNA
12 acteria with classical peptidoglycan such as
Coxiella,
Buchnera and members of the Rickettsia genus.
13 used by the obligate intracellular bacterium
Coxiella burnetii and can manifest as a flu-like illness
14 Coxiella burnetii and Chlamydia trachomatis are bacteria
15 For instance, mammalian pathogens such as
Coxiella burnetii and Francisella tularensis, as well as
16 s conserved in two other vacuolar pathogens,
Coxiella burnetii and Francisella tularensis.
17 Coxiella burnetii and Legionella pneumophila are evoluti
18 mber plasmids and encoded on plasmid QpH1 of
Coxiella burnetii and the F plasmid of Escherichia coli,
19 s of the primary adaptive immune response to
Coxiella burnetii are not well known.
20 Legionella pneumophila and
Coxiella burnetii are phylogenetically related intracell
21 Despite
Coxiella burnetii being an obligate intracellular bacter
22 o DNA-binding proteins have been detected in
Coxiella burnetii by southwestern (DNA-protein) blotting
23 Infection with
Coxiella burnetii can lead to acute and chronic Q fever.
24 Coxiella burnetii causes acute Q fever in humans and occ
25 Coxiella burnetii causes human Q fever, a zoonotic disea
26 enome of the obligate intracellular pathogen
Coxiella burnetii contains a large number of selfish gen
27 bited C. trachomatis but not T4SS-expressing
Coxiella burnetii development in a dose-dependent manner
28 The intracellular bacterial pathogen
Coxiella burnetii directs biogenesis of a parasitophorou
29 The intracellular bacterial pathogen
Coxiella burnetii directs biogenesis of a phagolysosome-
30 The obligate intracellular pathogen
Coxiella burnetii displays antiapoptotic activity which
31 The human pathogen
Coxiella burnetii encodes a type IV secretion system cal
32 Coxiella burnetii endocarditis is considered to be a lat
33 gh embyronated eggs, the Nine Mile strain of
Coxiella burnetii exhibits antigenic variation, a loss o
34 artonella quintana, Bartonella henselae, and
Coxiella burnetii from surgical heart valve tissue speci
35 , on replication of obligately intracellular
Coxiella burnetii in murine L-929 cells.
36 opting host Rho GTPases for establishment of
Coxiella burnetii infection and virulence in mammalian c
37 vaccine-induced protective immunity against
Coxiella burnetii infection, we compared the protective
38 antibody assay, weakly positive for phase II
Coxiella burnetii infection.
39 raphy for evidence of Bartonella species and
Coxiella burnetii infection.
40 Host control of
Coxiella burnetii infections is believed to be mediated
41 Coxiella burnetii infects mononuclear phagocytes, where
42 A 5.8-kb chromosomal fragment isolated from
Coxiella burnetii initiates plasmid replication in Esche
43 Coxiella burnetii is a Gram-negative bacterium that caus
44 Coxiella burnetii is a gram-negative obligate intracellu
45 Coxiella burnetii is a Gram-negative, obligate intracell
46 Coxiella burnetii is a highly infectious bacterium that
47 Coxiella burnetii is a highly infectious obligate intrac
48 Coxiella burnetii is a widespread zoonotic bacterial pat
49 Coxiella burnetii is an intracellular bacterial pathogen
50 Coxiella burnetii is an intracellular Gram-negative bact
51 Coxiella burnetii is an obligate intracellular bacterial
52 Coxiella burnetii is an obligate intracellular bacterial
53 Coxiella burnetii is an obligate intracellular bacterium
54 Coxiella burnetii is an obligate intracellular bacterium
55 Coxiella burnetii is an obligate intracellular bacterium
56 Coxiella burnetii is an obligate intracellular bacterium
57 Coxiella burnetii is an obligate intracellular bacterium
58 Coxiella burnetii is an obligate intracellular Gram-nega
59 Coxiella burnetii is an obligate intracellular pathogen
60 Coxiella burnetii is the bacterial agent of human Q feve
61 Coxiella burnetii is the causative agent of Q fever, a z
62 Coxiella burnetii load was high on-farm (2009), and lowe
63 Our recent study demonstrated that virulent
Coxiella burnetii Nine Mile phase I (NMI) is capable of
64 stand the mechanisms of formalin-inactivated
Coxiella burnetii phase I (PI) vaccine (PIV)-induced pro
65 line, he continued to have markedly elevated
Coxiella burnetii phase I antibody titers for 10 years a
66 on an extremely high antibody titer against
Coxiella burnetii phase I antigen.
67 The partition region qsopAB of the
Coxiella burnetii plasmid QpH1 was analyzed.
68 We present the first published case of
Coxiella burnetii prosthetic joint infection.
69 Coxiella burnetii replicates as distinct morphological f
70 The Q fever bacterium
Coxiella burnetii replicates inside host cells within a
71 Coxiella burnetii replicates within permissive host cell
72 We hypothesized that
Coxiella burnetii requires iron and employs an iron-regu
73 noculation with viable, but not inactivated,
Coxiella burnetii resulted in the increased expression o
74 Coxiella burnetii undergoes a poorly defined development
75 Coxiella burnetii undergoes a poorly defined development
76 ellular pathogens Legionella pneumophila and
Coxiella burnetii use a type IV secretion system to deli
77 Serodiagnosis for
Coxiella burnetii was performed for all patients.
78 The presence of
Coxiella burnetii was tested using immunofluorescence an
79 experimental infection with various doses of
Coxiella burnetii were tested by immunoblotting.
80 revious study demonstrated that treatment of
Coxiella burnetii with the phase I lipopolysaccharide (P
81 Q fever is caused by
Coxiella burnetii, a bacterium that persists in M2-polar
82 detect the obligate intracellular bacterium
Coxiella burnetii, a category B bioterrorism agent.
83 Coxiella burnetii, a Gram-negative obligate intracellula
84 Coxiella burnetii, a gram-negative obligate intracellula
85 Q fever is a zoonosis caused by
Coxiella burnetii, a unique bacterium that is widespread
86 and macrophage resistance to infection with
Coxiella burnetii, an obligate intracellular bacterium a
87 enic bacteria such as Enterococcus faecalis,
Coxiella burnetii, and Clostridium difficile.
88 ae, to an outer membrane protein (Com1) from
Coxiella burnetii, and to thioredoxin and thioredoxin-li
89 ella pneumoniae, Legionella longbeachae, and
Coxiella burnetii, as well as the plant pathogen Ralston
90 pathogens Brucella spp., Toxoplasma gondii,
Coxiella burnetii, Francisella tularensis, and Neospora
91 racellular bacterial agent of human Q fever,
Coxiella burnetii, has a remarkable ability to persist i
92 of Q fever, an infectious disease caused by
Coxiella burnetii, is associated with granuloma formatio
93 8 bacteria (Bartonella spp., Brucella spp.,
Coxiella burnetii, Leptospira spp., Rickettsia spp., Sal
94 The 1,995,275-bp genome of
Coxiella burnetii, Nine Mile phase I RSA493, a highly vi
95 oup I intron present in the 23S rRNA gene of
Coxiella burnetii, possesses a unique 3'-terminal adenin
96 fever, caused by the intracellular pathogen
Coxiella burnetii, relies mainly on serology and, in pre
97 t cell colonization by the Q fever pathogen,
Coxiella burnetii, requires translocation of effector pr
98 Reactivity to the HGE agent and to either
Coxiella burnetii, Rickettsia rickettsii, or Rickettsia
99 The 23S rRNA gene of
Coxiella burnetii, the agent of Q fever in humans, conta
100 Growth of
Coxiella burnetii, the agent of Q fever, is strictly lim
101 Coxiella burnetii, the causative agent of human Q (Query
102 For over seven decades,
Coxiella burnetii, the causative agent of human Q fever,
103 s considered fundamental to the virulence of
Coxiella burnetii, the causative agent of human Q fever.
104 Infections due to
Coxiella burnetii, the causative agent of Q fever, are u
105 Coxiella burnetii, the causative agent of Q fever, estab
106 Coxiella burnetii, the causative agent of Q fever, is a
107 Coxiella burnetii, the causative agent of Q fever, is a
108 Coxiella burnetii, the causative agent of Q fever, is an
109 Genetically distinct isolates of
Coxiella burnetii, the cause of human Q fever, display d
110 Coxiella burnetii, the cause of human Q fever, is an aer
111 Successful macrophage colonization by
Coxiella burnetii, the cause of human Q fever, requires
112 In contrast to mycobacteria,
Coxiella burnetii, the etiologic agent of Q fever, inhab
113 Coxiella burnetii, the etiological agent of acute and ch
114 Coxiella burnetii, the etiological agent of human Q feve
115 Coxiella burnetii, the etiological agent of Q fever in h
116 Coxiella burnetii, the etiological agent of Q fever, has
117 Coxiella burnetii, the etiological agent of Q fever, is
118 Coxiella burnetii, the etiological agent of Q fever, is
119 Coxiella burnetii, the etiological agent of Q fever, is
120 -Higashi syndrome and in cells infected with
Coxiella burnetii, the rickettsial organism that causes
121 he intracellular bacterial agent of Q fever,
Coxiella burnetii, translocates effector proteins into i
122 iffers in male and female mice infected with
Coxiella burnetii, we hypothesized that circadian genes
123 Da outer membrane protein similar to Com1 of
Coxiella burnetii, which we designate as dsbA2.
124 South Limburg, the Netherlands, reported 220
Coxiella burnetii-related abortions in 450 pregnant goat
125 used by the obligate intracellular bacterium
Coxiella burnetii.
126 group I introns in the sole 23S rRNA gene of
Coxiella burnetii.
127 canis, Ehrlichia ewingii, B. burgdorferi, or
Coxiella burnetii.
128 equence in a cloned IS1111a gene fragment of
Coxiella burnetii.
129 Q fever is an infection caused by
Coxiella burnetii.
130 lla pneumophila, Legionella longbeachae, and
Coxiella burnetii.
131 Q fever is a worldwide zoonosis caused by
Coxiella burnetii.
132 ave placentitis caused by a unique strain of
Coxiella burnetii.
133 Bacillus anthracis; Francisella tularensis;
Coxiella burnetii; and Ebola, Marburg, and Lassa fever v
134 Antibodies against
Coxiella burnetti, Francisella tularensis, and Rickettsi
135 chia chaffeensis, Rickettsia rickettsii, and
Coxiella burnetti, no significant cross-reactivity could
136 ion in the mean number of gold particles per
Coxiella call was observed at 12 h post-infection when c
137 this BSL2 model to investigate both host and
Coxiella components implicated in infection.
138 to CCVs for optimal homotypic fusion of the
Coxiella-
containing compartments.
139 ogen that directs the formation of an acidic
Coxiella-
containing vacuole (CCV) derived from the host
140 replicates inside host cells within a large
Coxiella-
containing vacuole (CCV) whose biogenesis relie
141 osome-derived intracellular niche termed the
Coxiella-
containing vacuole (CCV).
142 (T4SS) is critical for the formation of the
Coxiella-
containing vacuole and establishment of infecti
143 Dot/Icm system required acidification of the
Coxiella-
containing vacuole.
144 ytose virulent C. burnetii bacteria and form
Coxiella-
containing vacuoles (CCVs) and that C. burnetii
145 ative and epitope-tagged CBU0077 produced by
Coxiella displayed specific punctate localization at hos
146 In vivo,
Coxiella displays a tropism for mononuclear phagocytes w
147 urrently refractory to genetic manipulation,
Coxiella Dot/Icm substrates have been identified using b
148 the CCV and the intracellular replication of
Coxiella Effector proteins, translocated into the host c
149 nvestigated the role of CBU0077, a conserved
Coxiella effector that had previously been observed to l
150 that mitochondria are a bona fide target of
Coxiella effectors and MceA is a complex-forming effecto
151 s will dramatically aid our ability to model
Coxiella-
host cell interactions.
152 ensable for the intracellular replication of
Coxiella in HeLa and THP-1 cells and did not appear to p
153 system and Mycobacterium, Sphingomonas, and
Coxiella in the full-scale system.
154 Although minimal detection of
Coxiella in TLR2(-/-) mouse spleens was observed, greate
155 The
Coxiella-
infected cell thus provides a unique model for
156 tor (TNF) superfamily homolog in Drosophila,
Coxiella-
infected flies exhibit reduced mortality from i
157 r at the mitochondrial outer membrane during
Coxiella infection.
158 The marked stability of the
Coxiella intron RNAs is presumably conferred by their as
159 netii and Francisella tularensis, as well as
Coxiella-
like and Francisella-like endosymbionts (CLEs a
160 ira halophila) that are distantly related to
Coxiella,
making it difficult to determine whether the i
161 a citrate buffer-based medium termed complex
Coxiella medium (CCM) that contains a mixture of three c
162 atients, 3 had nonpyogenic microorganism IE (
Coxiella or Candida).
163 f Mycobacterium, Toxoplasma, Leishmania, and
Coxiella pathogenesis, a detailed description of the mec
164 ly enhanced in the presence of a recombinant
Coxiella RNA DEAD-box helicase (CBU_0670) relative to th
165 ter understand the role that introns play in
Coxiella'
s biology, we determined the intrinsic stabilit
166 that the ribozymes have a negative effect on
Coxiella'
s growth.
167 oxify endogenous hydroperoxide byproducts of
Coxiella'
s metabolism during intracellular replication.
168 genetic diversity and virulence potential of
Coxiella species.
169 hat the Drosophila TNF homolog Eiger and the
Coxiella T4SS are implicated in the pathogenesis of C. b
170 Protein substrates of the
Coxiella T4SS are predicted to facilitate the biogenesis
171 Engineering
Coxiella to express either MceA tagged with 3xFLAG or Mc
172 We also demonstrate that the
Coxiella type 4 secretion system (T4SS) is critical for
173 ntains elements homologous to the Legionella/
Coxiella Type IV secretion apparatus.
174 uolar-type (H+) ATPase (V-ATPase) within the
Coxiella vacuolar membrane was demonstrated by indirect
175 burnetii type 4B secretion system substrate
Coxiella vacuolar protein A (CvpA).
176 show that the C. burnetii secreted effector
Coxiella vacuolar protein B (CvpB) binds PI(3)P and phos
177 Four of the Dot/Icm substrates, termed
Coxiella vacuolar protein B (CvpB), CvpC, CvpD, and CvpE