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1 modelled by confined injection of adenoviral Cre recombinase.
2 ression are activated only after exposure to Cre recombinase.
3 27-bp cten promoter drives the expression of Cre recombinase.
4 h cell or tissue type-specific expression of Cre recombinase.
5 which Notch activation is induced in HSCs by Cre recombinase.
6 NIP isoform conditionally in the presence of Cre recombinase.
7 .4 kb promoter, and followed cell fates with Cre recombinase.
8 Rev3L could be conditionally inactivated by Cre recombinase.
9 blocker (loxTB), but could be reactivated by Cre recombinase.
10 cardiac-specific activation of the MerCreMer Cre recombinase.
11 AND We engineered a Hand1 allele expressing Cre recombinase.
12 interrupting reporter cassette is excised by Cre recombinase.
13 al allele of Lig3 that could be deleted with Cre recombinase.
14 optical voltage sensor under the control of Cre recombinase.
15 targeted to the early DCT using a DCT-driven Cre recombinase.
16 tantly, can be conditionally expressed using Cre recombinase.
17 disrupted in 2 different strains of mice via cre recombinase.
18 se line with sebocyte-specific expression of Cre recombinase.
19 essing (VIP+) GABAergic interneurons express Cre recombinase.
20 atty acid binding protein 4) promoter-driven Cre-recombinase.
21 tion of an adeno-associated virus expressing Cre recombinase (AAV-Cre) into the midbrain/pons of mice
23 ter fragment or by targeted integration of a Cre recombinase-activatable expression cassette driven b
24 isynaptic circuit, we constructed a panel of Cre recombinase-activated pseudorabies viruses (PRVs) th
25 ion of these lineages was only observed with Cre recombinase activation during early lung development
27 variably diminished (likely due to variable Cre-recombinase activity), but an overabundance of branc
31 serum albumin gene promoter/enhancer-driven Cre recombinase (albCre) transgene was used to investiga
32 approach also mediated efficient delivery of Cre recombinase and Cas9:sgRNA complexes into the mouse
33 l in mice by introducing a fusion protein of Cre recombinase and estrogen receptor (CreER) into the c
34 ated viral vectors containing genes encoding Cre recombinase and green fluorescent protein were micro
35 synthetic sequence through the action of the Cre recombinase and no competition from homologous recom
36 one oncogene (KRAS), achieved by delivering Cre recombinase and sgRNAs, which caused rapid lung tumo
38 hod RecWay assembly, as it makes use of both Cre recombinase and the commercially available Gateway c
39 t (KO) mouse lines, with viral expression of Cre-recombinase and a light-activated ion channel for op
40 , such as various fluorescent protein, Gal4, Cre-recombinase and dominant-negative receptor construct
42 ockdown, GRK2 gene deletion (GRK2(flox/flox)/cre recombinase) and overexpression of GRK2 and its regu
43 be labeled and manipulated, by expression of Cre recombinase, and demonstrated that Hes1(+) CACs do n
44 nsfected cells) can be achieved when Flp and Cre recombinases are expressed as Flp-2A-Cre and Flp-IRE
45 c markers (Sox2 and T) and tamoxifen-induced Cre recombinase-based lineage tracing to locate putative
48 bryonic endothelium stage (using VE-cadherin-Cre recombinase), but not from embryonic hematopoietic c
52 pha) mouse line and a gene construct driving Cre recombinase (Cre) expression in NSP cells, led to in
53 mouse strains have been developed, in which Cre recombinase (Cre) expression is driven by an RPE-spe
57 Here, we generated knock-in mice expressing Cre recombinase (Cre) under the control of the endogenou
58 in the lung by nasal delivery of adenoviral Cre recombinase (Cre), here we show that KRAS(G12D) expr
61 m by injecting an adenoviral vector encoding Cre recombinase (Cre)-regulated farnesylated green fluor
62 breeding these mice with lines that express Cre-recombinase (Cre) in early embryogenesis (EIIa-Cre)
63 pulse-labeled using the tamoxifen-dependent Cre recombinase, CreER(T2), expressed from the endogenou
65 describe a technique based on a destabilized Cre recombinase (DD-Cre) whose activity is controlled by
66 (+) .Foxo1 (L/L) mice with lineage-specific Cre recombinase deletion of floxed FOXO1 and compared th
67 hod that exploits GFP for gene manipulation, Cre recombinase dependent on GFP (CRE-DOG), a split comp
69 onal band of Broca cholinergic neurons using Cre recombinase-dependent adeno-associated virally media
71 ng of SOM-expressing neurons in s. oriens, a Cre recombinase-dependent construct for channelrhodopsin
73 s nicotine reward behaviors, we engineered a Cre recombinase-dependent gene expression system to sele
74 ermine MN-enriched miRNA expression, we used Cre recombinase-dependent miRNA tagging and affinity pur
76 a genetically tagged mouse model carrying a Cre-recombinase-dependent conditional allele of constitu
78 le gene deletion system based on a dimerised Cre recombinase (diCre) to target CRK3 and elucidate its
79 PR/Cas9 to facilitate use of the dimerisable Cre-recombinase (DiCre) that is frequently used to media
82 ingly, cells targeted by tamoxifen-inducible cre recombinase driven by nestin enhancer (Nes-creER) in
83 ngineered mouse model in which expression of Cre recombinase driven by the C-type lectin domain famil
84 constitutive activation of betacatenin using cre recombinase driven by the DEAD (Asp-Glu-Ala-Asp) box
85 ating alpha7nAChR(flox) with mice expressing Cre recombinase driven by the glial acidic fibrillary pr
86 generated the Mchr1-cre mouse that expresses cre recombinase driven by the MCHR1 promoter and crossed
87 s mouse strain to transgenic mice expressing Cre recombinase driven by the megakaryocyte (MK)-specifi
93 diated by KOR on DA terminals, we utilized a Cre recombinase-driven mouse line lacking KOR in DA neur
96 used two different mature RPE cell-specific Cre recombinase drivers to inactivate either Dicer1 or D
97 oral activation by tamoxifen (TAM)-inducible Cre recombinase Ela-CreERT in the submandibular gland (S
100 n the ROSA26R reporter mouse model utilizing Cre recombinase-encoding recombinant viruses harboring d
101 olerant mice; and (3) Tag-activation through Cre recombinase-encoding viruses in the liver and HCC de
103 pocytes prior to cold exposure, using Pdgfra-Cre recombinase estrogen receptor T2 fusion protein (Cre
104 ng growth factor-beta (TGF-beta) mediated by Cre recombinase expressed early in T cell development le
105 expressing a tamoxifen-inducible variant of Cre recombinase expressed under control of the Npr2-prom
106 ory neurons of the postnatal forebrain using Cre recombinase expressed under the control of the alpha
107 ed mouse, and then crossed this mouse with a Cre recombinase expressing mouse driven by the human gli
108 oblasts with 2 different tamoxifen-inducible Cre recombinase-expressing gene-targeted mouse lines.
110 allowed the identification of synapses from Cre recombinase-expressing or GAL4-expressing neurons in
111 neurons chemogenetically using a retrograde Cre-recombinase-expressing canine adenovirus-2 in combin
112 ic Cre strain for RPE gene function studies, Cre recombinase expression alone leads to RPE dysfunctio
113 te-tracing model based on timed and specific Cre recombinase expression and marker gene activation in
114 x/flox) embryos and rendered pikfyve-null by Cre recombinase expression displayed severely reduced DN
115 lidation of a transgenic mouse line in which Cre recombinase expression has been targeted to cells ex
116 ion of floxed KOR or floxed p38alpha MAPK by Cre recombinase expression in dopaminergic neurons block
118 system largely depends on the specificity of Cre recombinase expression in targeted stem or progenito
121 ducible membrane-bound reporter and targeted Cre recombinase expression to a subset of glial progenit
122 bone osteocytes, no differences in Mbtps1 or cre recombinase expression were observed in cKO SOL, exp
126 hat were crossed with DAT-Cre mice, in which Cre- recombinase expression is under dopamine transporte
130 Fig4 and crossed it with mice expressing the Cre recombinase from the neuron-specific synapsin promot
131 regions, we used transgenic mice expressing Cre recombinase from the Nkx2.1 promoter to ablate loxP-
132 ed cMyBP-C alleles and a tamoxifen-inducible Cre-recombinase fused to 2 mutated estrogen receptors to
135 stem to excise the selectable marker and the cre recombinase genes from transgenic banana cv. 'Grande
136 enic lines expressing a controllable form of Cre recombinase have become valuable tools for manipulat
138 ouse lines, Wnt1-Cre and P0-Cre that express Cre recombinase in a NC-specific manner, in combination
140 l La allele and used it in mice that express Cre recombinase in either B cell progenitors or the fore
141 system, in conjunction with mice expressing Cre recombinase in either parvalbumin-positive, somatost
143 validated a transgenic mouse line expressing cre recombinase in histidine decarboxylase-expressing ne
144 is used to specifically and inducibly drive Cre recombinase in ICC as a strategy to study GIST patho
146 fluorescent protein following activation by Cre recombinase in mice that express Cre recombinase in
150 o-associated viral (AAV) vector carrying the Cre recombinase in the hippocampus of mTORf/f mice recap
152 Z mice with transgenic mice that express the Cre recombinase in the pancreas, under control of the Pd
153 ntly translated into full-length, functional Cre recombinase in the presence of nonsense suppressors
154 porter showed that recombination mediated by cre recombinase in the Wt1(creEGFP) line occurs randomly
156 ggered by intravenous adenoviral delivery of Cre recombinase in transgenic mice expressing the hepato
157 line was assessed on interneurons expressing Cre recombinase in vasoactive intestinal peptide (VIP) o
158 ediated delivery of functional pDNA encoding Cre recombinase in vivo to tissues in transgenic Cre-lox
159 ocalized infusions of adeno-associated virus Cre-recombinase in adult, targeted knock-in mice with lo
161 roligins by stereotactic viral expression of Cre-recombinase in hippocampal CA1 region pyramidal neur
162 tamoxifen-inducible collagen type 2a1-driven Cre recombinase increased proliferation and beta-catenin
163 development of a transgenic mouse line where Cre-recombinase-induced expression of a mutant methionyl
164 e (MAPK) was selectively inactivated by AAV1-Cre-recombinase infection in specific brain regions or b
165 t two-hybrid method, CrY2H-seq, which uses a Cre recombinase interaction reporter to intracellularly
167 oinflammation in the DR by viral delivery of Cre recombinase into interleukin (IL)-1beta(XAT) transge
168 rom lentiviral delivery of shRNAs along with Cre recombinase into lungs of Loxp-stop-Loxp-KRas mice.
169 letion of Pbx1 by retroviral transduction of Cre recombinase into Pbx2-deficient SVZ stem and progeni
172 transgenic Cre line, in which expression of Cre recombinase is controlled by a previously identified
173 of numerous transgenic mouse lines in which Cre recombinase is expressed under the control of organ-
174 ne targeting using the bacteriophage-derived Cre recombinase is widely applied for functional gene st
175 ell adhesion in vivo, we utilized keratin-14 cre-recombinase (K14-cre) to inactivate Flcn in the mous
177 itional En mutants with floxed alleles and a cre recombinase line that becomes active in postmitotic
179 n-inducible disruption of Trpm7 and multiple Cre recombinase lines, we show that Trpm7 deletion befor
182 tes in a cultured pre-B cell line as well as Cre recombinase-mediated Bcl11a(lox/lox) deletion in exp
185 events in preclinical mouse models requires Cre recombinase-mediated conditional gene expression in
186 n of Panx1 (Panx1 (-/-) Apoe (-/-) ) or with Cre recombinase-mediated deletion of Panx1 in endothelia
190 ducible lineage tracing to fate map, through Cre recombinase-mediated fluorescent reporter gene activ
193 Previous studies have demonstrated that Cre recombinase-mediated recombination can lead to combi
194 ic recombination system based on dimerizable Cre recombinase-mediated recombination in the apicomplex
195 nger needed after integration was excised by Cre recombinase-mediated recombination of lox sites.
197 y" activated AR transgene expression through Cre recombinase-mediated removal of the LSL cassette.
198 eage tracings using cyclization recombinase (Cre) recombinase-mediated cell labeling represent the go
199 ion of Steroidogenic Factor-1 (SF1) to drive Cre-recombinase-mediated deletion of the brain muscle ar
200 centrosome amplification can be induced by a Cre-recombinase-mediated increase in expression of Polo-
203 h various neurone selective, promoter-driven Cre recombinase mice resulted in GCaMP3 expression in de
207 ty in mice and develop a new tissue specific Cre recombinase mouse model, we have established pCTEN-C
211 anterograde tracing using mice that express Cre recombinase only in neurons producing acetylcholine,
213 d nanoparticles with negatively supercharged Cre recombinase or anionic Cas9:single-guide (sg)RNA com
214 lleles are revertible in somatic tissues via Cre recombinase or splice-site-blocking morpholinos and
216 nanoparticles (MSNs) as carriers to deliver Cre recombinase protein into maize (Zea mays) cells.
217 ify mutations in the dimerization surface of Cre recombinase (R32V, R32M and 303GVSdup) that improve
218 tegrase system in place of the bidirectional Cre recombinase reaction; and (iii) gel extraction by DN
219 o achieve constitutive HH signaling) using a Cre recombinase regulated by the lysozyme M promoter.
221 These mice were crossed with mice expressing Cre recombinase, regulated by the villin or CD11c promot
222 in postnatal testis, and a dual fluorescent Cre recombinase reporter to label FLC and ALC in vivo.
226 d disruptive sequence that can be deleted by Cre recombinase, resulting in restored IL-1R1 gene expre
227 ated Vps34(f/f) mice, in which expression of Cre recombinase results in a deletion of exon 4 of Vps34
228 trogradely transported AAV vector expressing Cre recombinase (Retro-Cre-GFP) into the BLA (Experiment
229 developed a recombinant JHMV that expresses Cre recombinase (rJ-Cre) and infected mice that universa
230 eceptor (Lepr) was selectively ablated using Cre-recombinase selectively expressed in the hindbrain u
231 cells using smooth muscle protein 22-driven Cre recombinase (SMGRKO mice) and compared them with mic
234 s with mouse lines that ubiquitously express Cre recombinase starting early in development (e.g. MeuC
238 h PPARgamma was depleted using an adenovirus-Cre-recombinase system and in which adiponectin was also
239 combined with a split-intein-mediated split-Cre-recombinase system in mice to isolate, characterize,
240 the potent delivery of nM concentrations of Cre recombinase, TALE- and Cas9-based transcription acti
241 mary sarcomas generated with CRISPR-Cas9 and Cre recombinase technology had similar histology, growth
242 1(CreER) mice expressing tamoxifen-inducible Cre recombinase that allow for specific manipulation of
243 nic mouse under the control of both Flp- and Cre-recombinases that is an effective tool for circuit m
245 ce were crossed with mice transgenic for Pf4-Cre-recombinase (thrombopoietic deletion) or Cd11b-Cre-r
246 cinar cell-specific expression of knocked-in Cre recombinase through control of aquaporin 5 (Aqp5) pr
247 tability was mimicked with viral delivery of Cre recombinase to astrocytes in the LHA and rescued by
248 mbens with adeno-associated virus expressing Cre recombinase to create focal, homozygous Hdac3 deleti
249 lpha subunit and cell-specific expression of Cre recombinase to deplete PV(+) or SST(+) interneurons
251 itutively active ROSA26 locus in response to Cre recombinase to study the role of these phosphorylati
252 nd Probasin(Cre) alleles drive expression of Cre recombinase to the prostate epithelium and periepith
253 l recombinase technology using both FlpO and Cre recombinases to generate primary sarcomas in mice wi
254 kout mouse model using progesterone receptor-Cre-recombinase to achieve Pten and Grp78 (cPten(f/f)Grp
255 ation with adeno-associated virus expressing Cre-recombinase to generate focal homozygous deletions o
256 ice with selective expression of tdTomato or cre recombinase together with optogenetics to investigat
257 ice with a retinoid acid receptor 2 promoter-Cre recombinase transgene (Rarb-cre) expressed in embryo
258 ock-out mice carrying an aP2 promoter-driven Cre recombinase transgene showed a blunted response to t
259 KD1 gene and heterozygous for an aquaporin-2-Cre recombinase transgene to achieve collecting duct-spe
261 kout (floxed) Ptpn11 allele (Ptpn11(fl)) and Cre recombinase transgenic mice to delete Ptpn11 specifi
265 artifacts associated with beta-cell-specific Cre-recombinase transgenic models, raising questions abo
266 using mice that express tamoxifen-inducible Cre recombinase under control of osteopontin regulatory
267 hemiparkinsonian transgenic mice expressing Cre recombinase under control of the choline acetyltrans
268 IF-1alpha floxed mice with mice that express Cre recombinase under control of the glial fibrillary ac
269 U.1) was conditionally deleted in B cells by Cre recombinase under control of the Mb1 gene in Spib (e
270 erated mice that express tamoxifen-inducible Cre recombinase under control of the Plp1 promoter and c
271 n-C null mice and transgenic mice expressing Cre recombinase under control of the S100A4 promoter cro
272 ite cells in mice, using tamoxifen-inducible Cre recombinase under control of the satellite cell-spec
274 neered the expression of tamoxifen-inducible Cre recombinase under the control of a kidney-specific p
276 xpression in specific cell types, expressing Cre recombinase under the control of large genomic regul
277 yn(flox/flox) animals with mice carrying the Cre recombinase under the control of the Cd79a promoter,
278 mice with CX3CR1(CreER) mice, which express Cre recombinase under the control of the CX3C chemokine
279 lele of Pak4 with transgenic mice expressing Cre recombinase under the control of the nestin promoter
280 th muscle in Brg1(flox/flox) mice expressing Cre recombinase under the control of the smooth muscle m
281 manipulated in knock-in mice expressing the Cre recombinase under the endogenous parvalbumin promote
282 he circadian clock gene Bmal1 and expressing Cre recombinase under the endogenous Renin promoter (Bma
283 ZW-X mouse line with a mouse that expresses Cre recombinase under the influence of the NPY promoter.
284 leles floxed at exon 1 to animals expressing Cre recombinase under the pre-proglucagon promoter.
286 allele using transgenic mice that expressed Cre-recombinase under control of the ubiquitous CAG prom
289 ection of a BAAV vector encoding a bacterial Cre recombinase via canalostomy in adult mice with floxe
290 IL-22-expressing cells, a sequence encoding Cre recombinase was cloned into the Il22 locus, and IL22
291 ible system in which an optimized variant of Cre recombinase was expressed under the control of the V
292 delity lineage tracing after confirming that Cre recombinase was mesothelial specific and faithfully
294 ssibility that the bovine K5 promoter-driven Cre-recombinase was active early in trophoblast-lineage
295 tor cells with adenovirus expressing GFP and Cre-recombinase was successful in GRP78 ablation, and th
296 us from cells, Tre, an engineered version of Cre recombinase, was designed to target a 34-bp sequence
298 an adeno-associated viral vector coding for Cre recombinase, we found that focal restoration of OX2R
299 intestinal immune cells using a CD11c-driven Cre recombinase, which decreased anti-inflammatory media
300 ing fluorescent parasite strains that inject Cre recombinase with their rhoptry proteins (Toxoplasma-
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