ライフサイエンスコーパス: D-amino-acid oxidase

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1 of five structurally distinct inhibitors of d-amino acid oxidase.

2 relatives of ThiO are sarcosine oxidase and d-amino acid oxidase.

3 ttached flavin analogue in recombinant human d-amino acid oxidase.

4 ctral changes similar to those observed with d-amino acid oxidase.

5 ed by exposure to H(2)O(2) or D-alanine plus D-amino acid oxidase (40 U/mL).

6 r genes, disrupted in schizophrenia (DISC1), D-amino acid oxidase activator (DAOA), regulator of G-pr

7 Studies to date have implicated the D-amino acid oxidase activator complex (also known as G7

8 renia 1 (DISC1), D-amino-acid oxidase (DAO), D-amino-acid oxidase activator (DAOA, formerly known as

9 We suggest that the perturbation of the D-amino acid oxidase active site is due to the nonpolar

10 as pharmacological inhibition of endogenous D-amino acid oxidase activity revealed that D-serine is

11 Selective degradation of D-serine by D-amino acid oxidase and pharmacologic inhibition of SR

12 ontrast to the case of CH(3)CCl=NO(2)(-) and D-amino acid oxidase) because, in the enzyme-substrate e

13 tein active site and acts efficiently during d-amino acid oxidase catalytic turnover.

14 Using D-amino acid oxidase coupled with catalase for the deami

15 with the glycine oxidase-N-acetylglycine and d-amino acid oxidase-d-alanine complexes demonstrate tha

16 The D-AA with the class enzyme D amino acid oxidase (DAAO) generates H2O2.

17 separation and the specific reaction between D-amino acid oxidase (DAAO) and each D-AA biomarker avoi

18 A comparison with d-amino acid oxidase (DAAO) demonstrates that both enzym

19 because of the difference in expression of a D-amino acid oxidase (DAAO) enzyme between Schwann cells

20 ntermediate that accumulates in reactions of D-amino acid oxidase (DAAO) with alanine.

21 We have investigated the interaction of d-amino acid oxidase (DAAO) with single-walled carbon na

22 erivatives were synthesized as inhibitors of D-amino acid oxidase (DAAO).

23 o be due to D-serine undergoing oxidation by D-amino-acid oxidase (DAAO) before it reaches the brain.

24 in the protein framework of the flavoprotein D-amino-acid oxidase (DAAO).

25 ing the rapid dispersion of the class-enzyme D-amino acid oxidase (DAO) and L-amino acid oxidase (LAO

26 ermore, the microbiota induces production of d-amino acid oxidase (DAO) by intestinal epithelial cell

27 yotrophic lateral sclerosis (ALS)-associated D-amino acid oxidase (DAO) that reduces D-serine metabol

28 One such susceptibility gene encoding D-amino acid oxidase (DAO), an enzyme that metabolizes t

29 und for the D-serine plasma-CSF ratio at the D-amino-acid oxidase (DAO) gene (beta=-0.28; P=9.08 x 10

30 genes, disrupted in schizophrenia 1 (DISC1), D-amino-acid oxidase (DAO), D-amino-acid oxidase activat

31 expression of the d-serine degrading enzyme d-amino acid oxidase (Dao1) in the hippocampus of cocain

32 anner attenuated by scavenging D-serine with D-amino acid oxidase, deleting the enzyme responsible fo

33 loning and expression of a dao gene encoding D-amino acid oxidase from Schizosaccharomyces pombe in t

34 that selective degradation of d-serine with D-amino acid oxidase greatly attenuates NMDA receptor-me

35 e by prolonged treatment with d-serine and a d-amino acid oxidase inhibitor.

36 In contrast, incubation of D-amino acid oxidase or nitroalkane oxidase with 2-oxo-3

37 of histidine 307 with leucine in pig kidney D-amino acid oxidase perturbs its active site conformati

38 nylenediamine (PPD) layer and an R. gracilis D-amino acid oxidase (RgDAAO) layer.

39 2)O(2)-producing enzyme Rhodotorula gracilis D-amino acid oxidase (rgDAAO) selectively in astrocytes.

40 erine peak was confirmed unambiguously using D-amino acid oxidase to selectively remove D-serine from

41 n the photoreduction of the non-photosensory d-amino acid oxidase to the anion radical.

42 Application of d-amino acid oxidase, which degrades d-serine, reduced t

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