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1 DALY risk factors varied by age, with child and maternal
2 DALYs differed by age groups and regions, but not by gen
3 DALYs due to oral conditions increased 20.8% between 199
4 DALYs for the various device/voltage combinations were l
5 DALYs from non-communicable diseases--especially ischaem
6 DALYs were calculated for 291 causes, 20 age groups, bot
9 on) and foodborne toxoplasmosis with 825,000 DALYs (95% UI 561,000-1.26 million) resulted in the high
11 ost [51 d (-0.14 DALYs; 95% CI: -0.21, -0.08 DALYs) and 58 d (-0.16 DALYs; 95% CI: -0.23, -0.09 DALYs
14 er healthy life years were lost [51 d (-0.14 DALYs; 95% CI: -0.21, -0.08 DALYs) and 58 d (-0.16 DALYs
16 /=500 cells/microL ranged from $237 to $1691/DALY compared to 2010 guidelines; in Zambia, expanded el
18 tes for ischaemic stroke fell by 14% (9-19), DALYs lost by 17% (-11 to 21%), and mortality-to-inciden
19 s) with percentage of total 2010 DALYs, 2010 DALY rank, and DALY percentage change from 1990 to 2010
20 and protocols) with percentage of total 2010 DALYs, 2010 DALY rank, and DALY percentage change from 1
22 IV-positive persons ranged from $131 to $241/DALY and in Vietnam eligibility for CD4 </=500 cells/mic
23 mortality rates reduced by 23% (-18 to 25%), DALYs lost by 25% (-21 to 28), and mortality-to-incidenc
26 d congenital heart anomaly burden (1629/3049 DALYs per 100 000) was attributed to behavioral or metab
27 13% (95% CI 6-18), mortality by 37% (19-39), DALYs lost by 34% (16-36), and mortality-to-incidence ra
28 Tp-SP3+ to 1000 pregnant women averted 113.4 DALYs at an incremental cost of $825.67 producing an inc
30 burden of disease might be reduced by 56,400 DALYs, and life expectancy might increase by 0.15 y for
33 tly by 19% (1-15), mortality by 38% (32-43), DALYs lost by 39% (32-44), and mortality-to-incidence ra
40 burdens for outdoor air pollution (1,448,612 DALYs) and malaria (725,000 DALYs) in these countries.
42 and that these exposures resulted in 828,722 DALYs, with a range of 814,934-1,557,121 DALYs, dependin
45 ALYs globally (1.9% of all YLDs; 0.6% of all DALYs), implying an average health loss of 224 years per
47 age of total 2010 DALYs, 2010 DALY rank, and DALY percentage change from 1990 to 2010 for 15 skin con
49 (0.45-0.89) to 0.87 million (0.61-1.18); and DALYs from 31.7 million (30.2-33.3) to 42.5 million (39.
53 with estimates of cause-specific deaths and DALYs from the Global Burden of Disease Study 2010, to c
54 ally, and the number with related deaths and DALYs lost, is increasing, with most of the burden in lo
58 ietary patterns (per SD change in score) and DALYs were estimated by using a 2-part model and adjuste
59 the UK's rank for age-standardised YLLs and DALYs for their leading causes compared with EU15+ in 19
62 We compared funding with disease burden (DALYs and mortality) to show low levels of investment re
71 ath, disability-adjusted life years (DALYs), DALY-attributable risk factors, years of life lived with
74 ively compared with the potential downstream DALY benefits, as lives saved, during the use phase.
77 cohol misuse was the highest risk factor for DALYs (7.0% overall, 10.5% for males, and 2.7% for femal
78 ood pressure was the leading risk factor for DALYs in 2013, with an increase of 83.3% since 1990.
88 Nine countries had significantly greater DALYs from cutaneous leishmaniasis than the mean: Afghan
89 .3), and east Asia (56.5), with the greatest DALY burdens in children, adolescents, and the elderly.
93 infections (top rank in 1990; 44% decline in DALYs), stroke (fifth in 1990; 19% increase), diarrhoeal
94 o fetal losses was included and decreases in DALYs when comprehensive CT prevention measures were con
99 5-92.2) of the stroke burden (as measured in DALYs) was attributable to the modifiable risk factors a
101 n), foodborne trematodosis with 2.02 million DALYs (95% UI 1.65-2.48 million) and foodborne toxoplasm
104 conditions combined accounted for 15 million DALYs globally (1.9% of all YLDs; 0.6% of all DALYs), im
108 by up to 32,000, and avert up to 2.6 million DALYs at an estimated annual direct medical cost of US$2
109 tiary treatment, which prevented 6.6 million DALYs at an incremental cost-effectiveness ratio of $224
110 rs were found in China and India (66 million DALYs), a number greater than all developed countries co
112 DU was estimated to cause 4.0% (2.82 million DALYs, 95% UI 2.4 million to 3.8 million) of DALYs due t
113 ling can also avoid the loss of 0.98 million DALYs, but this option incurs more costs than it saves c
119 of 4.1 million (1.6 million to 6.8 million) DALYs from chronic obstructive pulmonary disease in 2015
121 maldehyde accounted for the vast majority of DALY losses caused by IAPs considered in this analysis,
124 e to HIV, 1.1% (216 000, 101 000-338 000) of DALYs due to HBV, and 39.1% (7.05 million, 5.88 million
129 in the UK was tobacco (11.8% [10.5-13.3] of DALYs), followed by increased blood pressure (9.0 % [7.5
131 th other developing countries (around 50% of DALYs attributable to non-communicable disease), whereas
133 k factors accounted for 39.6% (37.7-41.7) of DALYs; leading behavioural risk factors were suboptimal
135 s highest in Qatar and accounted for 4.9% of DALYs, followed by 4.8% in the United Arab Emirates, whe
136 actors accounted for 34.5% (32.4 to 36.9) of DALYs; the two leading behavioural risk factors were unh
138 , childhood wasting was the leading cause of DALYs in Afghanistan, Somalia, and Yemen, whereas unsafe
139 cable risk factors were the leading cause of DALYs in high-income and middle-income countries in the
142 aemic heart disease was the leading cause of DALYs worldwide in 2010 (up from fourth rank in 1990, in
147 DALYs, 95% UI 2.4 million to 3.8 million) of DALYs due to HIV, 1.1% (216 000, 101 000-338 000) of DAL
148 prioritized children] reduces the number of DALYs by 9% (for the same budget) or alternatively incur
152 ons contributed to the highest proportion of DALYs overall (6.0%), and in female indivduals (6.1%), b
153 -adjusted life-years (DALYs) by quintiles of DALYs annual increase from 1990 to 2013 to show rates of
161 dian CERs of caesarean sections ($315.12 per DALY) and orthopaedic surgery ($381.15 per DALY) are mor
162 Y averted) and WHO guidelines (ICER $127 per DALY averted), and remained highly cost effective even i
164 per DALY), and ophthalmic surgery ($136 per DALY) were similar to that of the BCG vaccine ($51.86-22
165 r DALY) and orthopaedic surgery ($381.15 per DALY) are more favourable than those of medical treatmen
166 of only school-aged children (ICER $167 per DALY averted) and WHO guidelines (ICER $127 per DALY ave
167 ess ratio (ICER) of Xpert scale-up ($169 per DALY averted, 95% credible interval [CrI] 104-265) is be
172 mental cost-effectiveness ratio of $2241 per DALY averted, when compared with that of primary prevent
173 positive adults ranged from $131 to $241 per DALY averted, and in Vietnam extending eligibility to pa
174 r clinical case averted and $80 (44-279) per DALY averted for the three-dose schedule, and of $25 (16
177 47.74 per DALY), general surgery ($82.32 per DALY), hydrocephalus surgery ($108.74 per DALY), and oph
180 moderate risk of low birthweight, $19.4 per DALY averted for low risk, and $4.0 per DALY averted for
181 ost-effectiveness threshold above $1,400 per DALY, canine interventions are at least 95% likely to be
182 emental cost-effectiveness ratio of $469 per DALY averted when compared with the status quo of no cov
183 gross domestic product per capita ($487) per DALY averted, and remain robust over a wide range of epi
184 a cost effectiveness threshold of US$500 per DALY averted, and discounted DALYs and costs at 3% per y
185 ischaemic heart disease ($500.41-706.54 per DALY) and HIV treatment with multidrug antiretroviral th
186 cost-effectiveness ratio (ICER) of $540 per DALY averted, $645 per life-year saved, and $511 per QAL
189 sensitivity analyses, the ICER was $7.7 per DALY averted for moderate risk of low birthweight, $19.4
190 er DALY), hydrocephalus surgery ($108.74 per DALY), and ophthalmic surgery ($136 per DALY) were simil
191 Rs of cleft lip or palate repair ($47.74 per DALY), general surgery ($82.32 per DALY), hydrocephalus
193 t of standard vaccinations ($12.96-25.93 per DALY) and bednets for malaria prevention ($6.48-22.04 pe
194 ive, and calculated the incremental cost per DALY averted ($/DALY) to compare competing strategies.
196 e greatest impact at an incremental cost per DALY averted of $5588 when compared with coverage of pri
201 regarded very cost effective if the cost per DALY averted was less than the country's 2012 per-head g
202 m: $1407) and cost effective if the cost per DALY averted was less than three times the per-head GDP.
203 ty and mortality, but incurs a high cost per DALY averted, resulting in lost opportunities to generat
207 follow-on test to microscopy, would produce DALY gains at a higher incremental cost and therefore is
209 as a direct result of oral diseases is rare, DALY estimates were based on years lived with disability
215 world regions of east Asia (age-standardised DALYs 136.32), southeast Asia (134.57), Oceania (120.34)
216 bies burden were Indonesia (age-standardised DALYs 153.86), China (138.25), Timor-Leste (136.67), Van
217 gest standard deviations of age-standardised DALYs between the 20 age groups were observed in southea
218 In 2013, the global mean age-standardised DALYs for cutaneous leishmaniasis was 0.58 per 100 000 p
222 re considered 'very cost-effective' if the $/DALY was less than the country's per capita gross domest
229 f disease due to incident hip fracture using DALYs in prospective cohorts in the CHANCES consortium,
230 d YLLs reduced by 41.1% (38.3-43.6), whereas DALYs were reduced by 23.8% (20.9-27.1), and YLDs by 1.4
234 ntal cost per disability adjusted life year (DALY) averted compared against gross national income per
235 , US$166) per Disability Adjusted Life Year (DALY) averted, PMI-funded interventions are highly cost-
236 ncidence, and disability-adjusted life year (DALY) estimates of oral conditions for the period of 199
237 e developed a disability-adjusted life year (DALY)-based estimate of the disease burden attributable
239 of Avahan per disability-adjusted life-year (DALY) averted versus a no-Avahan counterfactual scenario
241 were cost per disability-adjusted life-year (DALY) averted; cost per life-year saved; and cost per qu
243 n ($13.78 per disability-adjusted life year [DALY]) was similar to that of standard vaccinations ($12
246 der of 0.2-9 disability-adjusted life years (DALY) per year of operation was estimated for the model
247 3.6 million disability-adjusted life-years (DALY) per annum at an incremental cost-effectiveness rat
250 he number of disability-adjusted life years (DALYs) averted by a hydrocelectomy and identified the co
254 eart anomaly disability-adjusted life years (DALYs) in the poorest countries, compared with 51% of DA
256 an number of disability-adjusted life years (DALYs) per child during 6-60 mo of age [which includes c
257 ome regions, disability-adjusted life years (DALYs) per head are 40% higher in low-income and middle-
258 e changes in Disability Adjusted Life Years (DALYs) resulting from changes in exposure to air polluti
260 to units of disability-adjusted life years (DALYs) using ReCiPe end point analysis method and quanti
263 es of death, disability-adjusted life years (DALYs), DALY-attributable risk factors, years of life li
264 deaths, and Disability Adjusted Life Years (DALYs), for all diseases with sufficient data to support
268 s 33 million Disability Adjusted Life Years (DALYs); children under five years old bore 40% of this b
269 1.10 million disability-adjusted life-years (DALYs) and 25% of expected new infections and would prob
270 We used disability-adjusted life-years (DALYs) and years lived with disability (YLDs) metrics to
272 roke-related disability-adjusted life-years (DALYs) associated with potentially modifiable environmen
273 losses, and disability-adjusted life-years (DALYs) attributable to physical inactivity were estimate
274 deaths, and disability-adjusted life-years (DALYs) averted were calculated over a 15 year time horiz
275 ost: 346 000 disability-adjusted life-years (DALYs) averted with an additional cost of US$36.9 millio
276 38-1.48) and disability-adjusted life-years (DALYs) by 27.0 million (25.8-29.1), an increase of 2.7%
277 quantiles of disability-adjusted life-years (DALYs) by quintiles of DALYs annual increase from 1990 t
278 deaths, and disability-adjusted life-years (DALYs) due to listeriosis, by synthesising information a
280 e calculated disability-adjusted life-years (DALYs) for low birthweight, severe to moderate anaemia,
281 d $4,746 per disability-adjusted life-years (DALYs) for very cost-effective and cost-effective strate
282 5.1 million) disability-adjusted life-years (DALYs) in 2015, representing 7.6% of total global deaths
283 (YLDs), and disability-adjusted life-years (DALYs) in England, the UK, and 18 other countries (the f
284 ve estimated disability-adjusted life-years (DALYs) lost due to hip fractures using real-life follow-
285 e ratio, and disability-adjusted life-years (DALYs) lost, by age group (aged <75 years, >/= 75 years,
286 h impact, in disability-adjusted life-years (DALYs) lost, due to inhalation of a subset of IAPs in U.
289 ing cause of disability-adjusted life-years (DALYs) was ischaemic heart disease for males and lower r
293 lity (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) in Mexico and
295 and 13.0% of disability-adjusted life-years (DALYs), instead of the earlier estimates suggesting 21.2
296 lity (YLDs), disability-adjusted life-years (DALYs), life expectancy, and healthy life expectancy (HA
297 2.19 million disability-adjusted life-years (DALYs), respectively, and save >51 and 23 billion euros
298 deaths, and disability-adjusted life-years (DALYs), with 95% uncertainty intervals (UIs) calculated
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