ライフサイエンスコーパス: DEET

1 DEET (N,N-diethyl-3-methylbenzamide) is a 6-decade-old s

2 DEET (N,N-diethyl-meta-toluamide) is the world's most wi

3 DEET acts on this complex to potentiate or inhibit odour

4 DEET inhibits behavioral attraction to food odors in Dro

5 DEET inhibits odor-evoked currents mediated by the insec

6 DEET is the most widely used insect repellent worldwide.

7 DEET permeation through human skin in vitro was measured

8 DEET seems to act both at close range as a contact chemo

9 DEET stimulated action potentials in GRNs that respond t

10 DEET was potent in suppressing feeding as <0.1% DEET eli

11 DEET-based products provided complete protection for the

12 Since 0.02% DEET elicited action potentials, we conclude that DEET d

13 T was potent in suppressing feeding as <0.1% DEET elicited aversive behavior.

14 as used to randomise 795 households to a 15% DEET lotion and the remainder were given a placebo lotio

15 noninfected mosquitoes was achieved with 5% DEET, which corresponds approximately to a 30% dose in t

16 nment-issued insect repellent containing 75% DEET (N,N-diethyl-m-toluamide) in ethanol applied during

17 With the exceptions of bisphenol A and DEET, all TOrCs that were detected in the DS were well r

18 insect odorant receptor to odour ligands and DEET.

19 We further show that 6-MH and DEET can bind simultaneously to OBPs with other ligands.

20 We show that 6-MH and DEET can compete for the binding of attractive odorants

21 many continue to have practices of applying DEET (N,N-diethyl-3-methylbenzamide) based repellents th

22 MH binds to OBP1 at exactly the same site as DEET.

23 [para-chlorobenzoic acid (p-CBA), atrazine, DEET, and ibuprofen] was not significantly inhibited in

24 ited a more robust and longer-lived aversive-DEET memory.

25 Both DEET and caffeine were rapidly degraded by UV/FC and SS/

26 bition by the odour ligand and modulation by DEET.

27 Insect repellents containing DEET (N,N-diethyl-meta-toluamide) are highly effective,

28 osquitoes use their sense of smell to detect DEET, but there are currently two hypotheses regarding i

29 ion by all tested mosquito repellents except DEET.

30 lecule that are proposed to be important for DEET binding are not involved in binding of 6-MH.

31 not an ionotropic receptor, is necessary for DEET reception and repellency in Culex mosquitoes.

32 , and single sensillum recordings identified DEET-sensitive sensilla that were nonresponders in the i

33 Here we identify DEET-sensitive neurons in a pit-like structure in the Dr

34 re are major impediments to finding improved DEET alternatives because the receptors causing olfactor

35 Formulation B led to a 30% reduction in DEET permeation versus control.

36 oses, we observed a significant reduction in DEET-elicited protection against ZIKV-infected yellow fe

37 er characterized insect repellents including DEET.

38 on decreases effective repellency since less DEET is available for evaporation.

39 ch chemicals, N,N-diethyl-3-methylbenzamide (DEET) and caffeine, by low pressure ultraviolet (UV) lig

40 N,N-diethyl-3-methylbenzamide (DEET) is popular insect repellent which is considered sa

41 N,N-diethyl-3-methylbenzamide (DEET) is the most effective, and best studied, insect re

42 e, now called N,N-diethyl-3-methylbenzamide (DEET); a repellent containing IR3535 (ethyl butylacetyla

43 The two microcapsule DEET formulations exhibited 36-40% higher cumulative eva

44 Currently available non-DEET repellents do not provide protection for durations

45 andidate molecular targets for the action of DEET may aid in the design of safer and more effective i

46 time passed after training, the behavior of DEET-sugar-trained flies reversed from conditioned odor

47 Higher concentrations of DEET provided longer-lasting protection.

48 Reaction rate constants of DEET and caffeine with the respective radical species we

49 The degradation of DEET followed pseudo-first-order kinetics, whereas the d

50 ix under UV/FC and SS/FC, the degradation of DEET was significantly inhibited, but the degradation of

51 and Cl. were responsible for degradation of DEET, whereas ClO. related reactive species (ClOrrs), ge

52 compensated by applying a 5x higher dose of DEET.

53 We suggest that the effectiveness of DEET in pest control owes to its dual action in inducing

54 t olfactory- and contact-mediated effects of DEET are mechanistically distinct.

55 isms for the observed behavioural effects of DEET in the gas phase have been proposed: that DEET inte

56 planation for the broad-spectrum efficacy of DEET against multiple insect species.

57 acted to human hosts even in the presence of DEET, but are repelled upon contact, indicating that olf

58 acted by human odors despite the presence of DEET.

59 shown to have an efficacy similar to that of DEET-based repellents.

60 protection for durations similar to those of DEET-based repellents and cannot be relied on to provide

61 IR40a knockdown had no significant effect on DEET detection and repellency.

62 rosophila olfactory receptor neurons (ORNs), DEET is detected through a mechanism employing the olfac

63 exposure to low doses of GWIR chemicals PB, DEET, and permethrin induced depressive- and anxiety-lik

64 A formulation containing 23.8 percent DEET had a mean complete-protection time of 301.5 minute

65 g pyridostigmine bromide (PB) and pesticides DEET and permethrin during the war has been proposed as

66 including caffeine, meprobamate, primidone, DEET, carbamazepine, dilantin, naproxen, and triclosan.

67 The insect repellent DEET (N,N-diethyl-m-toluamide), which attenuates odor re

68 tion and sensitivity to the insect repellent DEET (N,N-diethyl-meta-toluamide).

69 l and susceptibility to the insect repellent DEET.

70 ontaminated with the common insect repellent DEET.

71 repellents are generally less effective than DEET-based products.

72 tem to block host odour recognition and that DEET actively repels insects by activating olfactory neu

73 elicited action potentials, we conclude that DEET directly activates of GRNs.

74 We conclude that DEET masks host odor by inhibiting subsets of heteromeri

75 Here, we demonstrate that DEET, picaridin, insect repellent 3535, and p-menthan-3,

76 urthermore, they support the hypothesis that DEET acts as a molecular 'confusant' that scrambles the

77 ET in the gas phase have been proposed: that DEET interferes with the olfactory system to block host

78 Here, we show that DEET blocks electrophysiological responses of olfactory

79 Here we show that DEET functions as a modulator of the odour-gated ion cha

80 Our measurements showed that DEET provided significantly higher protection than picar

81 Here, we showed that DEET suppressed feeding behavior in Drosophila, and this

82 Previously, it has been shown that DEET targets multiple components of the olfactory system

83 nstrate that flies independently process the DEET and sugar components to form parallel aversive and

84 controlled-release formulations in which the DEET active material was temporarily sequestered within

85 This DEET-aversive learning required the MB-MP1 dopaminergic

86 d or Ir40a is knocked down lose avoidance to DEET.

87 rsial as to whether ORNs respond directly to DEET or whether DEET blocks the response to attractive o

88 des aegypti females that were insensitive to DEET, and the selection of either sensitive or insensiti

89 dy suggests that behavioral insensitivity to DEET in A. aegypti is a genetically determined dominant

90 roantennography showed a reduced response to DEET in the selected insensitive line compared with the

91 crease in electroantennographic responses to DEET and a complete lack of repellency.

92 N,N-Diethyl-m-toluamide (DEET) is one of the most effective and commonly used mos

93 e times longer than N,N-diethyl-m-toluamide (DEET), the most widely used repellent throughout the wor

94 y used repellent N,N-diethyl-meta-toluamide (DEET), on the function of specific ORs of the African ma

95 s and to be effectively repelled by volatile DEET.

96 When DEET-based repellents are applied in combination with pe

97 her ORNs respond directly to DEET or whether DEET blocks the response to attractive odors.

98 We have investigated the extent to which DEET skin absorption can be reduced and evaporation sust

99 Moreover, differential conditioning with DEET versus shock suggests that formation of these disti