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1 DES for percutaneous coronary intervention appears to be
2 DES outcomes in the Liberal era were significantly bette
3 DES showed a good solubility of phenolic compounds with
4 DES treatment outcomes in patients with versus without D
5 DES use varied, from 56% in the Transitional era to 85%
6 DES were associated with a lower incidence of myocardial
7 DES, compared with BMS, were associated with a significa
8 DES-PCI showed similar survival to SA-CABG except for a
9 DESs are green solvents characterized by high availabili
10 analysis by dividing the study period into 3 DES eras: Transitional (April 23, 2003, to June 30, 2004
11 ational Patient Register, we evaluated 4,303 DES-PCI-treated patients with a surgical procedure and c
12 207 BMS-PCI (age 66.6 +/- 11.9 years); 2,381 DES-PCI (age 65.9 +/- 11.7 years); 2,289 SA-CABG (age 69
19 bjects in the prospective, multicenter ADAPT-DES study (Assessment of Dual Antiplatelet Therapy With
20 lar observational studies (PROMETHEUS, ADAPT-DES [the Assessment of Dual AntiPlatelet Therapy with Dr
22 elet Therapy With Drug-Eluting Stents (ADAPT-DES) registry, which included 8582 patients undergoing p
23 elet Therapy With Drug-Eluting Stents (ADAPT-DES) study was a prospective, multicenter registry study
24 elet Therapy With Drug-Eluting Stents (ADAPT-DES) was a multicenter, prospective study in patients un
25 ternal validation was performed in the ADAPT-DES (Assessment of Dual Antiplatelet Therapy With Drug-E
26 compared 8448 patients enrolled in the ADAPT-DES study (Assessment of Dual Antiplatelet Therapy With
27 derwent successful PCI with DES in the ADAPT-DES study, PDB occurred in 535 of 8,577 hospital survivo
30 hat tested different durations of DAPT after DES implantation: shorter dual antiplatelet therapy (S-D
31 as only present within the first month after DES-PCI, suggesting that surgery might be undertaken ear
32 nts requiring surgery within 12 months after DES-PCI had an increased risk of MI and cardiac death co
34 ear provides ischemic event protection after DES, ischemic event risk is perceived to be less after B
36 ogrel therapy from 6 months to 6 weeks after DES implantation was associated with a superior net clin
37 ssel revascularization were reduced with all DES compared with BMS, with cobalt-chromium EES, platinu
40 hed cohort, no significant association among DES (vs BMS) use and outcomes was observed at 1 and 2 ye
44 all 11,648 randomized patients (both BMS and DES), stent thrombosis rates were 0.41% vs 1.32% (n = 23
46 l no significant differences between BRS and DES (hazard ratio, 1.54; 95% confidence interval, 0.69-3
49 duals receiving multilesion PCI with BVS and DES and follow-up angiography at 6 to 8 months were stud
50 s the intraindividual performance of BVS and DES in patients receiving multilesion PCI and follow-up
53 ith 3-vessel or left main CAD, both CABG and DES-PCI were associated with substantial and sustained q
55 and unplanned reintervention for BMS-PCI and DES-PCI to respective propensity-matched SA-CABG and MA-
57 paring BP-BES versus currently U.S.-approved DES or BMS were searched through MEDLINE, EMBASE, and Co
59 ion was performed and choline chloride-based DES containing oxalic acid as a hydrogen bond donor with
60 safety and efficacy of durable polymer-based DES, bioabsorbable polymer-based biolimus-eluting stents
62 randomly assigned to biolimus-A9-eluting BP-DES, second-generation everolimus-eluting DP-DES, or thi
64 iodegradable-polymer drug-eluting stents (BP-DES) were developed to be as effective as second-generat
68 isk was defined by a prior MI rather than by DES implantation, the primary analysis provides moderate
70 ed, patient-blinded, randomized, comparative DES trial that enrolled patients from June 18, 2008, to
72 probability of treatment weighting to create DES- and BMS-treated groups whose observed baseline char
74 tion [CMR], 38 no rejection in desensitized [DES] and non-DES control groups) for reverse transcripti
77 of prenatal exposure to diethylstilbestrol (DES), a potent endocrine disruptor, with incidence of ut
78 pionate (TP), estrogen - Diethystilbesterol (DES) and glucocorticoid - Dexamethasone (DEX)), only and
80 DES, second-generation everolimus-eluting DP-DES, or thin-strut silicon-carbide-coated BMS in 8 Europ
82 tion durable-polymer drug-eluting stents (DP-DES) and as safe >1 year as bare-metal stents (BMS).
83 (predefined margin, 3.80%) compared with DP-DES (absolute risk difference, 0.78%; -1.93% to 3.50%; P
84 appeared barely noninferior compared with DP-DES and more effective than thin-strut BMS, but without
87 rization for multivessel disease with either DES or isolated CABG (n=893 each group) were analyzed.
90 total of 11,026 operations (66.3%) followed DES placement, and 5608 (33.7%) followed bare metal sten
91 s that showed decreased expression following DES treatment, miR-18b and miR-23a were found to possess
96 red in this study will contribute to further DES implementation in extraction of biologically active
97 correlates included use of early generation DES (HR=1.75, P=0.02), no procedural intravascular ultra
98 ]) compared with the use of first-generation DES (OR: 3.94 [95% CI: 2.20 to 7.05]; p for interaction
99 comes compared with BMS and first-generation DES and similar rates of cardiac death/MI, MI, and TVR c
101 BMS) and indirect evidence (first-generation DES with BMS and second-generation DES) from the randomi
104 ng bare-metal stents (BMS), first-generation DES, and newer generation DES in a large unselected nati
107 ials comparing stent types (first-generation DES, second-generation DES or BMS) were considered for i
112 , first-generation DES, and newer generation DES in a large unselected national data set from the BCI
114 d efficacy of BP-BES versus newer-generation DES coated with more biocompatible DP have not been inve
115 DAPT after implantation of newer-generation DES entails a tradeoff between reductions in stent throm
116 who received predominantly newer-generation DES to answer: A1) Use of DAPT for 12 months, as compare
117 g stent (DES) platforms, previous generation DES, and bare-metal stents (BMS) for percutaneous corona
118 r in patients treated with second-generation DES (odds ratio, 0.51; 95% confidence interval, 0.38-0.6
119 attenuated with the use of second-generation DES (OR: 1.54 [95% CI: 0.96 to 2.47]) compared with the
121 Implantation of BRS versus second-generation DES in chronic total occlusion was associated with simil
123 pool direct (comparison of second-generation DES to BMS) and indirect evidence (first-generation DES
125 attenuated with the use of second-generation DES, although the analysis may have been limited by the
126 r in patients treated with second-generation DES, but not with first-generation DES, compared with th
130 ar safety and efficacy of 2 newer-generation DESs in randomized participants with non-ST-elevation ac
132 he determinations of D and k(0) in glyceline DES by voltammetric studies using the Nicholson approach
133 in disease or a SYNTAX score </=22, however, DES-PCI was economically dominant compared with CABG, al
137 pansion were more frequently demonstrated in DES than in BMS patients, whereas neoatherosclerosis was
138 frames with neoatherosclerosis was lower in DES than in BMS (15.56% [12.24-28.57] versus, 56.41% [40
139 cutive lipid neointima length was shorter in DES than in BMS (2.4 [1.2-3.6] and 5.3 [3.0-7.0] mm; P=0
141 tomography imaging demonstrated that VLST in DES and BMS had a wide variety of abnormal findings, suc
145 b ischemia caused by infrapopliteal lesions, DES provide better 6-month patency rates and less amputa
147 t and intense with the BVS than the metallic DES and could be determined by patient baseline characte
149 ) with new-generation drug-eluting stents (n-DES) compared with bare-metal stents (BMS) and old-gener
150 of early/late ST in patients treated with n-DES (hazard ratio [HR]: 0.65; 95% confidence interval [C
151 8 no rejection in desensitized [DES] and non-DES control groups) for reverse transcription into cDNA,
154 scribe clinically and functionally the novel DES-p.Glu401Asp mutation as a cause of inherited left ve
155 interval [CI]: 0.43 to 0.99; p = 0.04) and o-DES (HR: 0.60; 95% CI: 0.41 to 0.89; p = 0.01) compared
156 S) and old-generation drug-eluting stents (o-DES) enrolled in the SCAAR (Swedish Coronary Angiography
157 er 31, 2010, and examined the association of DES versus BMS with 1-year outcomes: death; death or MI;
158 ed the long-term quality-of-life benefits of DES-PCI versus CABG for patients with 3-vessel or left m
159 The spectrophotometric characteristics of DES extracts of 65 EVOO samples were related to the tota
161 ffect of parameters such as pH, mol ratio of DES composition, volume of DES, volume of tetrahydrofura
163 re, we undertook a phase I/II pilot study of DES using a novel drug (anti-IL-6 receptor (IL-6R),Tocil
165 pH, mol ratio of DES composition, volume of DES, volume of tetrahydrofuran (THF) and sample volume w
168 ularization, compared with either BMS-PCI or DES-PCI, resulted in substantially enhanced death and re
170 kidney transplant recipients undergoing PCI, DES was associated with better clinical outcomes beyond
171 ll persists with newer biodegradable polymer DES generations against second-generation permanent poly
178 enge (P = 0.0007) observed, whereas prenatal DES or DEX treatment had no effects upon insulin secreti
181 atients with noninsulin-treated DM receiving DES, prolonged clopidogrel treatment was associated with
182 y and correlates of ST in patients receiving DES, specifically examining the impact of risk factors m
188 raction (DLLME) using deep eutectic solvent (DES) as the extracting solvent has been developed and ap
191 rape skin phenolics, deep eutectic solvents (DES) as a green alternative to conventional solvents cou
193 green, biorenewable deep eutectic solvents (DESs) at room temperature and in the presence of air, es
194 The utilization of deep eutectic solvents (DESs) in electrochemical studies has grown in recent yea
195 ntion using contemporary drug-eluting stent (DES) compared with coronary artery bypass graft (CABG) s
196 b BVS or Xience metallic drug-eluting stent (DES) implantation (Abbott Vascular, Santa Clara, Califor
199 let therapy (DAPT) after drug-eluting stent (DES) implantation is unclear, and its risks and benefits
200 lation (OAC) who undergo drug-eluting stent (DES) implantation require additional dual antiplatelet t
201 eatment of patients with drug-eluting stent (DES) in-stent restenosis (ISR) is more challenging than
202 eatment of patients with drug-eluting stent (DES) in-stent restenosis (ISR) remains a major challenge
205 necessity of polymers on drug-eluting stent (DES) platforms is dictated by the need of an adequate am
206 mparison of contemporary drug-eluting stent (DES) platforms, previous generation DES, and bare-metal
207 atelet therapy (DAPT) in drug-eluting stent (DES) recipients is 12 months to reduce the risk of late
209 ld (BVS) versus drug-eluting metallic stent (DES) in the same individual receiving multilesion percut
210 rst-generation drug-eluting coronary stents (DES) were introduced in 2003 to 2004, and their use resu
211 us durable-polymer (DP)-drug-eluting stents (DES) and bare-metal stents (BMS) by means of a network m
212 s of different types of drug-eluting stents (DES) and bare-metal stents (BMS); however, most prior tr
213 ts and early-generation drug-eluting stents (DES) and have not systematically evaluated the role of i
216 ic efficacy of coronary drug-eluting stents (DES) compared with bare metal stents (BMS), the relative
217 erventional cardiology, drug-eluting stents (DES) have shown better patency rates and are standard pr
219 ary intervention (PCI), drug-eluting stents (DES) reduce repeat revascularizations compared with bare
221 intervention (PCI) with drug-eluting stents (DES) versus bare metal stents (BMS) has not been studied
222 ons similar to metallic drug-eluting stents (DES), followed by complete bioresorption in approximatel
223 intervention (PCI) with drug-eluting stents (DES), improvements driven mainly by differences in myoca
224 th insulin who received drug-eluting stents (DES), prolonged clopidogrel treatment was associated wit
229 raft (SVG) lesions with drug-eluting stents (DES; paclitaxel- or everolimus-eluting stents) for reduc
230 -used, newer-generation drug-eluting stents (DESs) in a broad patient population is of interest.
233 significantly different in the 2 groups (SVG-DES: 15.0%, SVG-MT: 20.0%; hazard ratio, 0.65; 95% confi
234 re randomized (1:1) to DES implantation (SVG-DES) or medical treatment (SVG-MT) of the target SVG les
235 n MACE related to the target SVG lesion (SVG-DES: 10.0%, SVG-MT: 16.9%; hazard ratio, 0.53; 95% confi
236 rval, 0.20-1.43; P=0.21) or global MACE (SVG-DES: 36.7%, SVG-MT: 44.6%; hazard ratio, 0.73; 95% confi
238 time horizon, CABG remained more costly than DES-PCI, but the incremental cost-effectiveness ratio wa
241 er analyses in the fetuses, we observed that DES-mediated changes in miR expression may regulate gene
244 his segregation becomes unfavorable, and the DES structure is disrupted; instead, water-water and DES
246 Of the 66 family members screened for the DES-p.Glu401Asp mutation, 23 of them were positive, 6 we
250 major amputation rate remained lower in the DES group until 2 years post-treatment, with a trend tow
257 icantly greater with the BVS compared to the DES (6.7 +/- 12.6% vs. 2.9 +/- 11.5%; p = 0.003); the re
258 and cultured from 2 family members with the DES mutation (1 with mild and 1 with severe symptomatolo
262 d, pregnant C57BL/6 mice who were exposed to DES and miR profiles in thymocytes of both the mother an
263 Risk was strongest for women exposed to DES in the first trimester, when exposure corresponds to
264 atory demonstrated that prenatal exposure to DES induces thymic atrophy and apoptosis in the thymus.
265 At 5-year follow-up, CABG was superior to DES-PCI on several SAQ domains including angina frequenc
266 o November 2013, 10 patients unresponsive to DES with IVIg + Rituximab were treated with IVIg + TCZ.
268 nrolled patients receiving OAC who underwent DES implantation at 3 European centers between September
269 ith percutaneous coronary intervention using DES in patients with chronic kidney disease undergoing i
270 her percutaneous coronary intervention using DES or CABG between October 1, 2008, and September 30, 2
272 0 patients were treated with either XIENCE V DES (n=51) or BMS postdilated with the SeQuent Please DE
276 tly have complex coronary disease warranting DES but have a higher risk of bleeding from prolonged du
277 omized trial was conducted to assess whether DES also improve patency and clinical outcome of infrapo
278 o evaluate the surgical risk associated with DES-PCI compared with that in nonstented patients withou
283 rgoing successful coronary intervention with DES in whom routine platelet reactivity testing was perf
284 intermediate nonobstructive SVG lesions with DES was safe but was not associated with a significant r
285 h-risk, inpatient surgery, and patients with DES may benefit most from delay from a 6-month delay aft
288 teristics were more adverse in patients with DES-ISR, although they presented later and more frequent
293 ll-comers" who underwent successful PCI with DES in the ADAPT-DES study, PDB occurred in 535 of 8,577
294 ischemic and bleeding events after PCI with DES, thereby facilitating clinical decisions surrounding
298 ss of the Tryton Side Branch Stent Used With DES in Treatment of de Novo Bifurcation Lesions in the M
299 ss of the Tryton Side Branch Stent Used With DES in Treatment of de Novo Bifurcation Lesions in the M
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