1 on a specific and direct interaction between
DNA polymerases iota and eta with ubiquitin (Ub).
2 t the first nanomolar inhibitors of Y-family
DNA polymerases iota and eta.
3 ogether these kinetic data indicate that the
DNA polymerase iota catalyzed reaction is well suited fo
4 Comparing structures of
DNA polymerase iota complexed with N2-ethyl-Gua and Gua
5 e found that the Pol iota gene, encoding the
DNA polymerase iota,
contains 25 nucleotide polymorphism
6 The efficiency of a truncated, catalytic
DNA polymerase iota core enzyme was determined for nucle
7 te the adduct providing direct evidence that
DNA polymerase iota efficiently replicates past a minor
8 We have measured mRNA expression of
DNA polymerases iota,
eta, and zeta by using cultured Bu
9 DNA polymerase iota extends from the N2-ethyl-Gua:Cyt 3'
10 Of the four human Y-family members, human
DNA polymerase iota (
hpol iota) is the most error-prone.
11 Human
DNA polymerase iota (
hPoliota) promotes translesion synt
12 Human
DNA polymerase-iota (
hPoliota), a member of the Y family
13 DNA polymerase iota incorporates dCMP opposite N2-ethyl-
14 Human
DNA polymerase iota is a lesion bypass polymerase of the
15 Human
DNA polymerase iota is a low-fidelity template copier th
16 rase iota was measured and structures of the
DNA polymerase iota-
N2-ethyl-Gua complex with incoming n
17 the fidelity of nucleotide incorporation by
DNA polymerase iota opposite N2-ethyl-Gua and Gua using
18 Efficiency and fidelity of
DNA polymerase iota opposite N2-ethyl-Gua was determined
19 Human
DNA polymerase iota (
Pol iota) differs from other DNA po
20 The recently discovered human enzyme
DNA polymerase iota (
pol iota) has been shown to have an
21 DNA polymerase iota (
pol iota) is a conserved Y family e
22 Human
DNA polymerase iota (
pol iota) is a member of the Y-fami
23 DNA polymerase iota (
Pol iota) is an attractive candidat
24 DNA polymerase iota (
pol iota) is one of several recentl
25 However, human
DNA polymerase iota (
Pol iota), a member of the Y family
26 Of interest is human
DNA polymerase iota (
pol iota), which has been implicate
27 Mg(2+) on the enzymatic properties of human
DNA polymerase iota (
pol iota).
28 Human
DNA polymerase iota (
pol(iota)) is a recently discovered
29 eport here that an interaction between human
DNA polymerase iota (
poliota) and the proliferating cell
30 suggest that DNA polymerase eta (poleta) and
DNA polymerase iota (
poliota) are involved in somatic hy
31 The X-ray crystal structure of human
DNA polymerase iota (
Poliota) has shown that it differs
32 Human
DNA polymerase iota (
poliota) is a bypass polymerase of
33 DNA polymerase iota (
poliota) is a distributive error-pr
34 DNA polymerase iota (
Poliota) is a member of the Y famil
35 Human
DNA polymerase iota (
Poliota) is a member of the Y famil
36 Human
DNA polymerase iota (
poliota) is a Y-family polymerase w
37 A hallmark of human
DNA polymerase iota (
poliota) is the asymmetric fidelity
38 Here, we show that
DNA polymerase iota (
poliota), like poleta, associates w
39 Here, we show that
DNA polymerase iota (
poliota), like poleta, associates w
40 Here we determine how human
DNA polymerase-iota (
Poliota) promotes error-free replic
41 at the active site suggests movements in the
DNA polymerase iota polymerase-associated domain to acco
42 ate kinetic measurements revealed that human
DNA polymerase iota preferentially inserts the correct n
43 ation and extension opposite N2-ethyl-Gua by
DNA polymerase iota was measured and structures of the D
44 The structure of
DNA polymerase iota with N2-ethyl-Gua at the active site