ライフサイエンスコーパス: DNA probe

1 rescence emission of the fluorescein-labeled DNA probe.

2 ition sites placed at the middle of a 300 bp DNA probe.

3 (95%) were determined to be S. pneumoniae by DNA probe.

4 s simultaneously determined using a specific DNA probe.

5 netic beads binding to a chromosome-specific DNA probe.

6 to a digoxigenin-labeled telomere antisense DNA probe.

7 (MB)-modified oligo-adenine (A)-guanine (G) DNA probe.

8 BH3 shows preference for the single-stranded DNA probe.

9 specific 16S ribosomal RNA probe and genomic DNA probe.

10 osition of the part RNA complementary to the DNA probe.

11 n - and their incorporation onto a stem loop DNA probe.

12 nded DNA molecule with tandem repeats of the DNA probe.

13 the PNA probes were higher than those of the DNA probes.

14 A probes, in comparison to the corresponding DNA probes.

15 h excess fluorescently labeled complementary DNA probes.

16 ybridization of oligonucleotide sequences to DNA probes.

17 ase and were enzymatically incorporated into DNA probes.

18 complete desorption of noncovalently linked DNA probes.

19 lized TFs with fluorescently labeled cognate DNA probes.

20 yses combined with fluorescent detection via DNA probes.

21 vities that span reported values for PNA and DNA probes.

22 ucleic acids ("targets") in solution and the DNA probes.

23 icrog/mL (1.25 fM) by adopting well-designed DNA probes.

24 hen used in comparison to unmodified labeled DNA probes.

25 of fluorescence emission from Cy5 labeled on DNA probes.

26 ility shift assays with cAMP-CRP and several DNA probes.

27 e protein-DNA complex (A complex) with short DNA probes.

28 n of small-molecule binding to surface-bound DNA probes.

29 discrimination in comparison with unmodified DNA probes.

30 ed more frequently in early periodontitis by DNA probes.

31 he species level by use of whole-chromosomal DNA probes.

32 isolates identified using whole-chromosomal DNA probes.

33 unmodified miRNAs hybridized to immobilized DNA probes.

34 NA targets is a significant barrier to short DNA probes.

35 nces between the transcripts and the arrayed DNA probes.

36 ng region of mRNA to be targeted by multiple DNA probes.

37 hylene blue label on the surface-immobilized DNA probes.

38 beacons (MBs) and two single-stranded helper DNA probes.

39 DC/NHS chemistry for covalent conjugation of DNA probes.

40 NT surface and amine groups on the detection DNA probes.

41 s were coated with the first target-specific DNA probe 1 (1pDNA) and bio-barcode DNA, which acted as

42 The primary DNA probe (1(0)P, which was of two different sequences w

43 were coated with the second target-specific DNA probe 2 (2pDNA) that was able to recognize the other

44 using fluorescently labeled single-stranded DNA probes, a wide-field epifluorescence microscope and

45 omic hybridization with purified MIC and MAC DNA probes against a whole genome oligonucleotide microa

46 staining, cross-species chromosome painting, DNA probe analyses, and scanning electron microscopy to

47 sis of ganglioside mimics were identified by DNA probe analyses.

48 DNA probe analysis (Gen-Probe, San Diego, CA), the bile

49 was evaluated by a colony-forming assay and DNA probe analysis at different time points.

50 DNA probe analysis for 40 bacteria was used to evaluate

51 , and bacterial populations were measured by DNA probe analysis.

52 r the presence of 40 periodontal bacteria by DNA probe analysis.

53 ccupancies of the corresponding factors on a DNA probe and determining probe recovery by quantitative

54 Immobilized DNA probe and hybridized target densities on these surfa

55 The Au NP is conjugated to a DNA probe and is allowed to hybridize with the DNA targe

56 cation of anodic poles of the array with the DNA probe and its hybridization with the targets, genoty

57 Only a 4-6 bp overlap between a DNA probe and miRNA was required for efficient ligation

58 rtant for evolutional biology as well as for DNA probe and PCR technologies.

59 MC/Au) nanocomposite as tracing tag to label DNA probe and polythiophene (PT) as immobilization platf

60 ogy (CPT), which utilizes a chimeric DNA-RNA-DNA probe and RNase H, is a rapid, isothermal probe ampl

61 -AC with 25 nt, Cy5 labeled DNA target and a DNA probe and study the spatiotemporal dynamics using ep

62 The hybridization between ss DNA probe and target ss DNA was detected by reduction in

63 optimized to excite a fluorophore-conjugated DNA probe and tested using real meat samples to obtain a

64 Salmonella nucleic acid (mRNA) using magneto-DNA probes and a miniaturized nuclear magnetic resonance

65 Thiolated DNA probes and alkanethiols were stably immobilised on t

66 ng pediatricians' offices were assayed by 74 DNA probes and by PCR to Streptococcus mutans.

67 ation module to perform the hybridization of DNA probes and cells/tissue samples.

68 Using a protocol based on biotinylated DNA probes and streptavidin coated magnetic beads we wer

69 Herein, interaction between DNA probes and target molecule are also investigated and

70 ctionalized with two sets of single-stranded DNA probes and then used as optical probes for DNA detec

71 y affected by the presence of guanine in the DNA probes and whether DNA is present in its single-stra

72 immobilization of the single strand DNA (ss-DNA) probe and hybridization with the target miRNA seque

73 he MWCNTs concentration, the amount of MWCNT-DNA probe, and the volume of the test probe) that govern

74 rface, (2) steric hindrance between tethered DNA probes, and (3) nonspecific adsorption of the attach

75 rter molecule, functionalized with thiolated DNA probes, and stabilized and protected by low molecula

76 e demonstrate that conditionally fluorescent DNA probes are capable of distinguishing variations of a

77 Novel fluorogenic DNA probes are described.

78 Beads coated with single-stranded DNA probes are linked to surfaces coated with single tar

79 yeast proteome microarray was screened with DNA probes; Arg5,6, a well-characterized mitochondrial e

80 rbon electrode, and also applying a specific DNA probe as well as hematoxylin for electrochemical ind

81 tification and target adequacy controls in a DNA probe assay to identify isolates as Staphylococcus a

82 racterized amine-terminated, single-stranded DNA probes attached to amine-reactive commercial microar

83 Synthetic DNA probes attached to microarrays usually range in leng

84 ce was functionalized with the 24-nucleotide DNA probes based on the West Nile virus sequence (Kunjin

85 A DNA probe-based species identification system (PCR-enzym

86 roteins were used to cross-link to different DNA probes bearing thiol-tethered bases.

87 Adsorption of a fluorophore-labeled DNA probe by graphene oxide (GO) produces a sensor that

88 le enzymatic synthesis of oligonucleotide or DNA probes by polymerase-catalyzed primer extension.

89 ates that a specially designed multistranded DNA probe can differentiate point mutations in the range

90 Split G-rich DNA probes can assemble into active peroxidase-mimicking

91 reviously characterized; this indicates that DNA probes can be developed for rapid detection and surv

92 Here, we present novel magneto-DNA probes capable of rapid and specific profiling of pa

93 tion does not necessarily require the use of DNA probes centered on polymorphic nucleotides and may e

94 The study directly supports different DNA probe chemical and spatial microenvironments within

95 Sensor response to thiolated DNA probe chemisorption, hsa-let-7a hybridization, label

96 The control line exploits an immobilized DNA probe complementary to the labeled aptamer, forcing

97 ved using nine distinct approximately 23-mer DNA probes complementary to regions distributed along th

98 pulations of beads, each functionalized with DNA probes complementary to the target molecule.

99 An acetylene-terminated DNA probe, complementary to a specific "Hepatitis C" vir

100 DNA probes conjugated to AuNPs were used to detect a DNA

101 t purified YdcI protein specifically binds a DNA probe consisting of its own promoter sequence.

102 DNA probes consisting of amine-terminated oligonucleotid

103 g varied ratios of unlabeled and dye-labeled DNA probes contact-printed onto commercial arraying surf

104 hat the K protein binds to a single-stranded DNA probe containing the CT-rich element of R3, which is

105 VPA-induced binding of nuclear proteins to a DNA probe containing the relevant ARE sequence in the Ga

106 -DNA adducts in greater detail, biotinylated DNA probes containing a site-specific cisplatin 1,2-d(Gp

107 SH2-MSH6 (MutSalpha) dimer effectively bound DNA probes containing ascorbate-Cr-DNA and cysteine-Cr-D

108 sible non-covalent attachment of amphiphilic DNA probes containing hydrophobic units attached to the

109 nding experiments with circularly permutated DNA probes containing one ICP4 binding site revealed tha

110 We have developed fluorescent DNA probes containing quenched fluorophore-tetrazine and

111 Molecular beacon DNA probes, containing 1-4 pyrene monomers on the 5' end

112 Hybridization studies using a DNA probe corresponding to an 89-bp conserved region of

113 Mean total DNA probe counts were similar precleaning but were highe

114 Counts, percentages of DNA probe counts, and percentages of teeth colonized for

115 all case-patient isolates by tests with the DNA probe Cp3-13.

116 At the low DNA probe densities typically used in assays (<10(13)/cm

117 Immobilized DNA probe density and DNA target hybridization in these

118 We also quantified the DNA probe density on electrode surface by the chronocoul

119 cumvents issues resulting from the very high DNA probe density, allowing highly enhanced hybridizatio

120 We optimized the conditions for DNA probe deposition to allow accurate detection of a we

121 n immunoprecipitation assays, KLF15 binds to DNA probes derived from the core promoter and the surfac

122 uce a novel partially double-stranded linear DNA probe design.

123 zation in situ using C0T-1 (highly repeated) DNA probes detects surprisingly abundant euchromatin-ass

124 n Chile and southern Peru were tested with a DNA probe directed at a kinetoplast DNA segment of Trypa

125 vity of several targets with double-stranded DNA probes (dsProbes) of varying affinity.

126 Immobilization of DNA probes during pyrrole electropolymerization is a sim

127 By using a group of DNA probes, each containing a mismatched base pair or an

128 elf-assembly process and functionalized with DNA probes, enabled detection of target DNA molecules (1

129 surface chemistry influences on immobilized DNA probe environments that affect target capture effici

130 The MBI/FBI-labeled DNA probes exerted low fluorescence that was increased 2

131 assay method in which the pairs of unlabeled DNA probes firstly bind to HPV16 E6 and E7 RNAs to form

132 ntional cytogenetics and fluorescent-labeled DNA probes (fluorescence in situ hybridization [FISH]),

133 sing approaches involving aptamers, enzymes, DNA probes, fluorescent probes, interacting proteins and

134 A binary DNA probe fluorescently reports the presence of 0.5% of

135 V DNA is captured via magnetic bead-modified DNA probes, followed by an antidigoxigenin-peroxidase de

136 ontains a locked nucleic acid (LNA) modified DNA probe for improving hybridization efficiency, while

137 elogene (VEL) genomic assay is a qualitative DNA probe for vanA and vanB in enterococci.

138 nique that can use specifically circularized DNA probes for detection of target nucleic acids and pro

139 achieved by introducing two short unlabeled DNA probes for each specific DNA sequence and by perform

140 this study, we have used lanthanide-labeled DNA probes for the detection of miRNAs on membranes usin

141 ion elements such as antibodies/antigens and DNA probes for the proposition of immunosensors and geno

142 uorescence in situ hybridization with use of DNA probes for these sites demonstrates that 11q23 is cl

143 cess of target recycling that rapidly shears DNA probes from the particles, generating an AuNP aggreg

144 We report the DNA probe functionalized electrochemical genosensor for

145 rrays were prepared by randomly distributing DNA probe-functionalized microspheres (3.1-microm diamet

146 ltonics) to 16S rRNA/hsp65 sequencing and/or DNA probes (Gen-Probe) for mycobacterial identification.

147 e mismatches (SBMs) using ferrocene-modified DNA probe has been investigated in the present manuscrip

148 quantitatively against that of DNA probes or DNA probe/helper combinations directed against the same

149 DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) th

150 Consequently, neutral ethylated DNA probe hold a great promise for DNA sensing, especial

151 The rapid kinetics and ability to ligate DNA probes hybridized to RNA with short complementary se

152 Seventy of the 77 DNA probes hybridized with one or more of the nonamplifi

153 ngly being adopted as suitable platforms for DNA probe immobilization and signal transduction.

154 mined the optimal experimental condition for DNA probe immobilization and target interrogation.

155 A exhibited an optimum value at intermediate DNA probe immobilization densities.

156 It is demonstrated that using the E-DNA probe in the FET measurement could have a significan

157 oying universal, fungus-specific primers and DNA probes in an enzyme immunoassay format (PCR-EIA).

158 f encoded microbeads and a high stability of DNA probes in cell-free extracts.

159 microarray demonstrated the ability to print DNA probes in less than 1 min and to detect 10-pM target

160 with sequence specific capture and labeling DNA probes in solution and then the complex is pulled do

161 Thus, we can report the development of DNA probes in the form of photon-controllable (thrombin)

162 ent to recruit LHP1 to GAGA motif-containing DNA probes in vitro.

163 Gel shift experiments with a CpG-methylated DNA probe indicate that recombinant MBD3L1 can supershif

164 s with nuclear extracts and a CpG-methylated DNA probe indicate that recombinant MBD3L2 can displace

165 r finding that a fluorophore inserted into a DNA probe instead of one of the internal nucleotides may

166 In this proposed strategy, a dumbbell-shaped DNA probe is designed to integrate target binding, magne

167 AMs has revealed that the surface density of DNA probes is highly dependent on the composition of the

168 clonal antibodies; FISH used PathVysion HER2 DNA Probe kit; PCR utilized differential PCR (D-PCR) met

169 This assay consists of a linear DNA probe labeled with a fluorophore in the middle.

170 ast, Saccharomyces cerevisiae using a single DNA probe labeled with a single fluorophore.

171 d with a capture DNA sequence and a reporter DNA probe labeled with the enzyme, both made to be highl

172 ins with the covalent conjugation of capture DNA probe labeled with thiol at its 3'terminal onto the

173 Single-stranded DNA probes labeled with fluorescein amidite (FAM-ssDNA),

174 robe, the size of Au-NP, the amount of Au-NP-DNA probe, lateral flow membranes, and the concentration

175 face capture produced by MCU addition to the DNA probe layer correlates with structural and conformat

176 bsequent signal amplification by a secondary DNA probe linked to AuNS.

177 We designed phosphorothioate-modified DNA probes linked to superparamagnetic iron oxide nanopa

178 Importantly, we have reproduced DNA probe microarray immobilization densities in macrosc

179 complex (B complex) formed by ICP4 with long DNA probes migrates just behind the A complex in the ele

180 pe hybridization reactions among GNP-labeled DNA probe, miRNA-215 and biotin-modified DNA probes were

181 s performed in a single tube with one set of DNA probe-modified gold nanoparticles (AuNPs), a single

182 ical methods and compared for morpholino and DNA probe monolayers.

183 idization events occurred among biotinylated DNA probes, mutant DNA, and complementary DNA, the resul

184 cases reflects an aggregate affinity for the DNA probes, not the affinity for binding to a single sit

185 The DNA probe of atxA gene efficiently hybridizes with diffe

186 target by using two different newly designed DNA probes of IS711 gene.

187 sensitivity approximately 4-fold compared to DNA probes of the same sequence.

188 bilized single stranded thiolated DNA (ss th-DNA) probe of N. meningitides onto the nanostructured Zn

189 t immobilization of purified single-stranded DNA probe oligomers on cleaned gold microelectrodes.

190 n is specific and selective for atxA gene by DNA probe on the electrode surface.

191 The method of non-covalent immobilization of DNA probes on an uncharged, non-reactive, hydrophilic su

192 rescence intensity results using end-labeled DNA probes on gold show little observable fluorescence o

193 In this work, the immobilization of DNA probes on nanostructured metal-dielectric/semiconduc

194 s was applied to check the immobilization of DNA probes on pretreated samples.

195 ty of different types of hybrids formed with DNA probes on surfaces is affected by probe spacing.

196 pad and the dispensing cycles of the capture DNA probes on the test-zone), the biosensor could detect

197 This assay uses a pair of specific DNA probes, one being covalently conjugated to an MNP fo

198 Target DNA serves as a template for two DNA probes, one of them covalently attached to upconvers

199 was compared quantitatively against that of DNA probes or DNA probe/helper combinations directed aga

200 sDNA density had a profound influence on the DNA probe orientation at the surface and subsequent targ

201 PCR were studied relative to an unamplified DNA probe (PACE2) and to an expanded, independent diagno

202 2 to efficiently join adjacent chimeric RNA-DNA probe pairs hybridized in situ on fixed RNA target s

203 Most reported fluorescent sensors relied on DNA probes physisorbed by GO, which may suffer from nons

204 , self-complementary, methylene blue-labeled DNA probe possessing a triple-stem structure.

205 Using an optimized process of DNA probe preparation to minimize the effect of contamin

206 bridization of the AIV H5 capture and target DNA probes produced a capacitance reduction of -13.2 +/-

207 The specificity of short synthetic DNA probes raises the hope of distinguishing small diffe

208 cence activation in which a phosphine on one DNA probe reduces an azide group in a linker on a second

209 identify proteins that interact with RNA and DNA, probe regions of DNA hypersensitivity, and measure

210 poration of the CF3-(Ph)ImdC analogue into a DNA probe resulted in 6-fold fluorescence quenching of t

211 of locked nucleic acid (LNA) residues in the DNA probes resulted in greater discrimination between ex

212 The hybridization of the DNA target with the DNA probes results in instantaneous aggregation of AuNPs

213 s used as a detection technique coupled with DNA probe sandwich assemblies and gold nanoparticles (GN

214 DNA probes separated by as little as 50 kb can be resolv

215 alent immobilization of the thiol-terminated DNA probe sequence (pDNA) using displacement reaction is

216 hybridization properties of a 15-nucleotide DNA probe sequence that has additional m adenine nucleot

217 ned and fabricated to covalently attach both DNA probing sequence and nonfluorescent Raman tags to th

218 ing polymer that is covalently modified with DNA probe sequences.

219 The population of immobilized DNA probe sites is quantified by counting individual DNA

220 e tuned by simply changing the length of the DNA probe (six (A6) or 12 (A12) adenines).

221 Using a B30.2-domain-encoding DNA probe so derived from the hematopoietic kidney (pron

222 sing high ionic strength, high-concentration DNA probe solutions to permit direct XPS surface analysi

223 sing two pairs of unique capture- and signal-DNA probes specific for each target.

224 e d-AuNPs were stabilized by single stranded DNA probe (ssDNAp).

225 Fluorescently labeled DNA-probe strands are immobilized on PEGylated gold nano

226 On surfaces, when immobilized MO or DNA "probe" strands hybridize with complementary DNA "ta

227 ybridization reactions among the FCN-labeled DNA probe, target DNA and capture DNA probe were perform

228 DNA probes targeting these antigens were designed and ev

229 DNA sensor based on the use of a clamp-like DNA probe that binds a complementary target sequence thr

230 We have designed a reversible fluorescent DNA probe that can be used to determine the concentratio

231 Here, we show a novel DNA probe that can transduce transient membrane encounte

232 A secondary DNA probe that contained 36 bases with alkaline phosphat

233 nsor involved the immobilization of a 17-mer DNA probe that is complementary to a specific gene seque

234 The surface consists of single-stranded DNA probes that are covalently anchored to a self-assemb

235 e enhanced local effective concentrations of DNA probes that are involved in PiDSD, and identified a

236 el mobility assays with use of 7 overlapping DNA probes that collectively span this entire region.

237 an be amplified to yield small (100-2000 bp) DNA probes that in aggregate will generate a single, str

238 e 3'-OH of target strands that hybridized to DNA probes that were printed on a surface.

239 nS) were synthesized and functionalized with DNA probes that were specific to each pathogen.

240 This resulted in adsorptively bound DNA-probes that were used to detect complementary, label

241 ated it to one terminus of a single-stranded DNA "probe" that was attached by its other terminus via

242 fect of contaminants in commercial thiolated DNA probe, the electrode surface was functionalized with

243 implicity of ELISA, and the specificities of DNA probes, this method rapidly detected and differentia

244 interface of the biosensor by surface-bound DNA probes through a hybridization process.

245 we have optimized the concentrations of the DNA probe to decrease the hybridization time to 10 min.

246 A single DNA probe to detect all seven of the most medically impo

247 r, no attempt has yet been made to conjugate DNA probe to Fe3O4/TMC/Au nanocomposite as electrochemic

248 his system uses quantum dots (QDs) linked to DNA probes to capture DNA targets.

249 ionalized gold nanoparticles and fluorescent DNA probes to capture target DNA in free solution, and w

250 rammable and specific binding of dye-labeled DNA probes to count integer numbers of targets.

251 technique, which uses fluorescently labeled DNA probes to detect chromosomal alterations in cells, o

252 All FISH studies were done using DNA probes to detect t(4;14)(p16;q32), t(11;14)(q13;q32)

253 idelines for designing non-perfectly matched DNA probes to target DNA sequences as desired throughout

254 ences via sandwich hybridization of specific DNA probes to the target sequence.

255 0 A chromosome pairs by FISH using the yeast DNA probe together with a karyotyping cocktail.

256 ontained nA and sU were able to hybridize to DNA probes under conditions where the unmodified hairpin

257 ning buffers, the concentration of detection DNA probe used in the preparation of FCN-DNA conjugates,

258 deletion and that the confusion is caused by DNA probes used in the experiment.

259 ic acid (MPA) for immobilization of specific DNA probe via avidin layer on the surface.

260 nvolves attachment of a biotinylated primary DNA probe via its 5'-amine-terminus to the streptavidin-

261 oelectrodes is exploited to bind the capture DNA probes via amide coupling with the carboxylic groups

262 The np-Au electrodes modified with 26-mer DNA probes (via thiol-gold chemistry) enabled sensitive

263 This DNA probe was characterized and used in photo-cross-link

264 A capture DNA probe was immobilized on the test zone of the latera

265 The DNA probe was initially designed to have a complementary

266 One DNA probe was tagged with fluorescein; the other was bio

267 endent binding of RcoM(Bx)-1 to a variety of DNA probes was demonstrated in vitro.

268 2-mul usage for FISH deoxyribonucleic acid (DNA) probe was used, which is five-fold reduction when c

269 R assay, using a FAM labeled double quenched DNA probe, was at least 40x more sensitive than the TaqM

270 Using a "U"-shaped DNA probe, we report that DNA bending by charged bZIP pe

271 f two nucleic acid amplification tests and a DNA probe were affected by swab order.

272 CN-labeled DNA probe, target DNA and capture DNA probe were performed on the lateral flow biosensor.

273 omplementary DNA target with the immobilized DNA probes were calculated by using kinetic evaluation s

274 Eighteen different 50-mer single-stranded DNA probes were covalently attached to 3.1-mum microsphe

275 DNA probes were covalently attached to the waveguide sur

276 Specific DNA probes were designed and used in real-time PCR assay

277 Eight 100-nucleotide single-stranded DNA probes were designed complementary to the E6-E7 gene

278 In MQDS, pathogen specific DNA probes were designed to form a hairpin structure and

279 Capture and detection DNA probes were designed.

280 terial in the biosensors and biochips field, DNA probes were electrografted, using diazonium chemistr

281 led DNA probe, miRNA-215 and biotin-modified DNA probes were performed on the lateral flow device.

282 Biotinylated capture DNA probes were then attached to the detection antibodie

283 Six near-identical DNA probes were used in this study; the main differences

284 In this approach, short DNA probes were utilized to first quantify the amount of

285 lternative strategy for surface tethering of DNA probes, where highly reactive glassy carbon (GC) sub

286 ily accessible to tiled 8-mer LNA and 15-mer DNA probes, whereas an unmodified version of the same DN

287 exing approach based on the fast exchange of DNA probes which enables efficient and rapid multiplexed

288 n using gold nanoparticles conjugated with a DNA probe, which is complementary to the 16S ribosomal R

289 15nm was used as a tag to label a detection DNA probe, which was complementary with the part of targ

290 ll line, a chromosome 15 centromere-specific DNA probe with a fluorescent tag attached was reacted wi

291 detect the hybridization of single stranded DNA probe with its complementary target strand.

292 ination efficacy and detection capacity of a DNA probe with two inserted UNA monomers (UNA2), and com

293 UNA monomers (UNA2), and compared it to the DNA probe with two purposefully inserted mutations (DNAM

294 TP-2Bzim, TP-3Bzim) are light-up fluorescent DNA probes with a long wavelength emission (>580 nm).

295 for enhancing the performance of oligomeric DNA probes with an RNA target.

296 uential liquid hybridization of biotinylated DNA probes with mutant DNA and complementary DNA, the re

297 The assembly of libraries containing DNA probes with specific modifications and the availabil

298 two dyes provides a simple method to prepare DNA probes with unique fluorescent signatures.

299 It can be used as a luminescent DNA probe, with emission switched on through DNA binding

300 ity is achieved with polynucleotide-extended DNA probes, with the unzipping of a miRNA-DNA duplex in